Abstract: An initial set of one or more data stores is selected for storing configuration data of a first client of a configuration discovery service. Configuration data for various items of the client's computing environment are stored at the initial set for a first time period. A configuration item, whose records were being stored at a first data store, is identified as a candidate for a data store change. Storing of at least some configuration data of the item at a different data store is initiated.

Abstract: In a provider network, a risk score for transferring computing resources between a source computing network and a provider network is determined based on an analysis of the computing resources. The analysis includes identifying configuration data associated with the computing resources and mapping the configuration data to scoring criteria to determine the risk score. A user interface is provided that is indicative of the risk score. The risk score is indicative of a predicted likelihood of success of the transfer.

Abstract: Cell deposition and staining apparatuses and methods are disclosed herein. In particular, the deposition and staining apparatuses disclosed herein provide low-volume, automated bench top systems for depositing and staining cellular samples on a cytological slide. An example deposition and staining apparatus includes a housing having an access door; a substrate processing holder located within the housing configured to hold one or more substrates and/or one or more substrate cartridges, wherein the substrate processing holder is accessible when the access door is in an open configuration; at least one opening located at least partially above at least a portion of the substrate processing holder; a spray nozzle configured to dispense a gaseous substance into the substrate processing area; a user interface configured receive an input from a user, and in response to receiving the input, cause execution of a pre-programmed protocol; and a waste and/or reagent holder element.

Abstract: A network-based discovery system and service are disclosed that provide client discovery services to a number of clients over a network. The network-based discovery system includes a database that stores discovery information of client network-based resource configurations. The discovery information may be obtained from client resources by client-side discovery components that are placed on client resources, obtain the discovery information and that send the information to the discovery system. The discovery system analyzes the discovery information to determine the client network-based resource configurations and generates client network-based resource configuration representations for the respective clients. The client network-based resource configuration representation may include a description of, and dependencies among, a plurality of computer-based resources.

Abstract: A surgical system includes a tubular shaft having a wall defining an outer surface and an inner surface disposed about an inner space, the tubular shaft having a proximal end and a distal end. The surgical system also includes at least one light emitter and at least one light sensor disposed at the distal end of the tubular shaft, and one or more leads or conductors electrically coupled to the at least one light emitter or the at least one light sensor. The one or more leads may be disposed in clearances defined by first and second jaws. Alternatively or in addition, the one or more conductors may be formed on a flexible substrate, and the flexible substrate may have a deformed state in which the substrate is disposed in the inner space.

Abstract: At a network-accessible service, a request is received from a client to enable access by a migration facilitator to a configuration record collection of the client. A response to a migration candidate identification query is generated using the configuration record collection and transmitted to the facilitator. An indication of a proposal associated with migrating at least a portion of the client's computing environment to a different computing environment with assistance from the facilitator is provided to the client.

Abstract: A surgical system includes at least one light emitter generating light at a first intensity and an array of light sensors including a least one row of light sensors, individual light sensors in the row of light sensors adapted to generate a signal including a non-pulsatile component. The system also includes a controller coupled to the array of light sensors, the controller including an analyzer to determine the magnitudes of the non-pulsatile components at the individual light sensors in the row of light sensors, to determine if the non-pulsatile component transitions from a higher magnitude to a lower magnitude and from a lower magnitude to a higher magnitude, and if so, to determine if the first intensity should be changed to a second intensity.

Abstract: A surgical system used to determine a size of a vessel within a region proximate to a working end of a surgical instrument includes at least one light emitter disposed at the working end of the surgical instrument, and at least one light sensor disposed at the working end of the surgical instrument opposite the at least one light emitter, the at least one light sensor adapted to generate a signal comprising a first pulsatile component and a second non-pulsatile component. The system also includes a controller coupled to the at least one light sensor, the controller comprising a splitter to separate the first pulsatile component from the second non-pulsatile component and an analyzer to quantify the size of the vessel within the region proximate to the working end of the surgical instrument based on the first pulsatile component.

Abstract: A surgical system used to detect tissue and/or determine tissue characteristics within a region proximate to a working end of a surgical instrument includes at least one light emitter disposed at the working end and configured to be activated to emit photons, and at least one light sensor disposed at the working end, facing in a common direction as the at least one light emitter, and configured to receive photons emitted from the at least one light emitter and exiting from the region, the at least one light sensor configured to receive photons over a limited time period. The system also includes a controller coupled to the at least one light sensor, the controller configured to operate the at least one light sensor to receive photons over the limited time period after a time delay from activation of the at least one light emitter.

Abstract: A surgical system used to determine if a vessel is within a region proximate to a working end of a surgical instrument includes at least one light emitter configured to emit light of two different wavelengths. The system also includes at least one light sensor disposed opposite the at least one light emitter, the at least one light sensor configured to detect light at the two different wavelengths and to provide a signal having a pulsatile and a non-pulsatile component for each wavelength. The system further includes a controller coupled to the at least one light sensor and configured to determine and indicate if the vessel is a ureter within the region proximate to the working end of the surgical instrument based on a ratio and a symmetry of a dip in the non-pulsatile component.

Abstract: Aspects of the present disclosure include methods, apparatuses, and computer readable media for receiving at least one TP packet, computing a current data rate or an end time of a low throughput phase, determining if TP is in the low throughput phase, aggregating the at least one received TP packet or an ACK relating to the at least one received TP packet in response to determining that the TP is not in the low throughput phase, and transmitting the ACK to a sending device.

Abstract: At a network-accessible service, a request is received from a client to enable access by a migration facilitator to a configuration record collection of the client. A response to a migration candidate identification query is generated using the configuration record collection and transmitted to the facilitator. An indication of a proposal associated with migrating at least a portion of the client's computing environment to a different computing environment with assistance from the facilitator is provided to the client.

Abstract: A surgical system includes at least one light emitter generating light at a first intensity and an array of light sensors including a least one row of light sensors, individual light sensors in the row of light sensors adapted to generate a signal including a non-pulsatile component. The system also includes a controller coupled to the array of light sensors, the controller including an analyzer to determine the magnitudes of the non-pulsatile components at the individual light sensors in the row of light sensors, to determine if the non-pulsatile component transitions from a higher magnitude to a lower magnitude and from a lower magnitude to a higher magnitude, and if so, to determine if the first intensity should be changed to a second intensity.

Abstract: The present invention relates to detection of cancer, or assessment of risk of development thereof. In particular, the present invention provides compositions and methods detection of field carcinogenesis by identification of ultrastructural and molecular markers in a subject.

Abstract: A sample collection apparatus or device, various abrasive devices or components, and methods for their use, are provided for collecting samples from within a mammalian body. Tissue collection and sample preparation is the gold standard in cytology. Many cell scrapers and abrasives and their respective methods of collection destroy cellular tissue, decreasing the quality of the sample. Devices for obtaining cell and tissue samples, can comprise a collection device which is inserted into a cavity, a finger worn collection device, a glove based collection device and respective abrasive instruments or components.

Abstract: The present invention provides systems, devices, and methods for cell collection and/or cell smearing (e.g., on a slide). In particular, provided herein is an cell collection device, a translating slide holder, systems comprising such devices, and methods of use thereof.

Abstract: Automated cell staining systems and methods are disclosed herein. In particular, the staining systems disclosed herein provide low-volume, automated bench top staining systems for staining biological samples contained on a cytological slide.

Abstract: A system and method for compensation of angular distortions in a system utilizing light emitters and light sensors disposed on non-parallel jaws may include determining a first point at a first side of a region of interest and a second point at a second side of the region of interest, determining a linear curve including the first and second points, and utilizing the linear curve to remove the angular distortion from the region of interest between the first and second points, A system and method for compensation of angular distortions may alternatively include modeling a non-pulsatile illumination pattern according to the intensities of individual emitters, comparing the pattern according to the model against a non-pulsatile illumination pattern detected using the light sensors, and varying the intensities of the individual emitters based on the comparison until angular distortion has been removed.

Abstract: A surgical system used to determine if a vessel is within a region proximate to a working end of a surgical instrument includes at least one light emitter disposed at the working end of the surgical instrument, the at least one light emitter adapted to emit light of at least two different wavelengths. The system also includes at least one light sensor disposed at the working end of the surgical instrument opposite the at least one light emitter, the at least one light sensor adapted to detect light at the at least two different wavelengths. The system further includes a controller coupled to the at least one light sensor and adapted to determine a ratio of the light absorbed at the least two different wavelengths, and to indicate if an artifact within a region proximate to the working end of the surgical instrument is a vessel based on the ratio.