Patents by Inventor Harry S. Courtney

Harry S. Courtney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Group A streptococcal M-related proteins and methods of use
    Patent number: 9650425
    Abstract: Immunogenic group A streptococcus M-related polypeptides and peptides and immunogenic compositions comprising these M-related polypeptides and peptides are provided herein that evoke cross-opsonic and cross-protective anti-GAS and anti-SDSE antibodies in animals. Also provided are preparations comprising immunogenic compositions that comprise M-related polypeptides, peptides, or fusion proteins and that further comprise at least one additional group A streptococcus immunogen, such as an M peptide or Spa peptide.
    Type: Grant
    Filed: February 11, 2014
    Date of Patent: May 16, 2017
    Assignee: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
    Inventors: James B. Dale, Harry S. Courtney
  • GROUP A STREPTOCOCCAL M-RELATED PROTEINS AND METHODS OF USE
    Publication number: 20140227313
    Abstract: Immunogenic group A streptococcus M-related polypeptides and peptides and immunogenic compositions comprising these M-related polypeptides and peptides are provided herein that evoke cross-opsonic and cross-protective anti-GAS and anti-SDSE antibodies in animals. Also provided are preparations comprising immunogenic compositions that comprise M-related polypeptides, peptides, or fusion proteins and that further comprise at least one additional group A streptococcus immunogen, such as an M peptide or Spa peptide.
    Type: Application
    Filed: February 11, 2014
    Publication date: August 14, 2014
    Inventors: James B. Dale, Harry S. Courtney
  • METHOD OF DELIPIDATION OF HDL USING SERUM OPACITY FACTOR TO PREVENT, INHIBIT, AND/OR REVERSE ATHEROSCLEROSIS
    Publication number: 20110118173
    Abstract: This invention relates to delivering a therapeutically active serum opacity factor or an anti-atherosclerotic therapeutic lipoprotein generated from interaction with serum opacity factor to an individual that has or is at risk for atherosclerosis. This can be accomplished by in vivo or ex vivo delivery methods.
    Type: Application
    Filed: August 22, 2008
    Publication date: May 19, 2011
    Inventors: Henry J. Pownall, Harry S. Courtney
  • Streptococcal serum opacity factors and fibronectin-binding proteins and peptides thereof for the treatment and detection of streptococcal infection
    Publication number: 20040151737
    Abstract: Provided herein are S. pyogenes serum opacity factor (SOF)- and S. dysgalactiae fibronectin-binding protein-based polypeptide, polynucleotide, and antibody compositions and methods. Compositions provided herein are effective in eliciting opsonic and/or protective antibodies specific for S. pyogenes and/or S. dysgalactiae and, consequently, are useful inter alia for the treatment, diagnosis, and monitoring of streptococcal infections, including S. pyogenes and S. dysgalactiae infections, and diseases associated with S. pyogenes and S. dysgalactiae infections ranging from, but not limited to, mild and generally self-limiting infections of the pharynx and skin to more severe and life-threatening infections, such as toxic shock syndrome and necrotizing fasciitis.
    Type: Application
    Filed: February 4, 2004
    Publication date: August 5, 2004
    Applicant: University of Tennessee
    Inventor: Harry S. Courtney