Abstract: Biologic information is obtained concerning a member of a population by obtaining a sample of placental tissue from the member, storing the sample without embedding it in an embedding medium, retrieving from storage the sample associated with the member and thereafter analyzing it for biologic information. Storage may be in a fixative such as formalin or a formalin substitute. When a tissue sample from more than one member is collected, a library is created that may be used for a variety of purposes, including reducing the incidence of medical malpractice claims, identification of members such as paternity testing or suspect identification, pharmaceutical development and epidemiological surveys and research.

Abstract: Biologic information is obtained concerning a member of a population by obtaining a tissue sample from the member, storing the sample without embedding it in an embedding medium, retrieving from storage the sample associated with the member and thereafter analyzing it for biologic information. The tissue sample may be all or part of the member's placenta. Storage may be in a fixative such as formalin or a formalin substitute. Storage may also be by other means of preserving such as freezing or the like. When a tissue sample from more than one member is collected, a library is created that may be used for a variety of purposes, including reducing the incidence of medical malpractice claims, identification of members such as paternity testing or suspect identification. The library may also be used for pharmaceutical development and epidemiological surveys and research.

Abstract: Methods of diagnosing an abnormality in endometrial glandular development in a woman suspected of being infertile are disclosed. Methods of predicting abnormal endometrial glandular development are also disclosed. In addition, methods of assessing the suitability of the endometrium for embryo implantation in a woman undergoing ovulation induction are disclosed. Further, methods of evaluating the effect of a hormonal protocol on endometrial glandular development in a woman undergoing a hormonal protocol to produce a mock cycle are disclosed. Methods of evaluating a hormone replacement therapy protocol in a woman undergoing hormone replacement therapy are disclosed. Further, methods of diagnosing endometrial glandular mitotic arrest in a woman suspected of having endometrial hyperplasia are disclosed.

Abstract: Methods of diagnosing an abnormality in endometrial glandular development in a woman suspected of being infertile are disclosed. Methods of predicting abnormal endometrial glandular development are also disclosed. In addition, methods of assessing the suitability of the endometrium for embryo implantation in a woman undergoing ovulation induction are disclosed. Further, methods of evaluating the effect of a hormonal protocol on endometrial glandular development in a woman undergoing a hormonal protocol to produce a mock cycle are disclosed. Methods of evaluating a hormone replacement therapy protocol in a woman undergoing hormone replacement therapy are disclosed. Further, methods of diagnosing endometrial glandular mitotic arrest in a woman suspected of having endometrial hyperplasia are disclosed.

Abstract: Therapeutic and diagnostic applications by the detection and manipulation of mouse ascites golgi factor produced by endometrium and present in other exocrine tissues and defined by an antibody found in mouse ascites are provided by this invention.

Abstract: Immunologic binding partners which specifically bind to oncofetal fibronectin but not normal adult fibronectin or blood plasma fibronectin and methods of diagnosing and treating oncogenesis and reproductive abnormalities employing the same.

Abstract: Therapeutic and diagnostic methods of use for the growth factor transforming growth factor .beta., are provided by this invention. In accordance with preferred embodiments, methods of determining and improving competence of a conceptus toward uterine implantation are provided as are methods for determining female infertility in mammals.

Abstract: Therapeutic and diagnostic applications by the manipulation of a unique protein produced by trophoblasts and defined by the monoclonal antibody FDC-6 are provided by this invention.