Patents by Inventor Hassan Almoazen

Hassan Almoazen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190337886
    Abstract: The present invention relates to a pharmaceutical composition for the treatment of anaphylaxis formulated for rapid delivery, in one embodiment, the delivery vehicle is a rapidly dissolving film. The films contain an epinephrine or a novel epinephrine pro-drag for fee rapid treatment of anaphylaxis in a patient. This invention relates to pharmaceutical compositions made by modifying the physicochemical properties of epinephrine in order to enhance its permeability through biological membranes (sublingual and buccal membranes). Several prodrugs of epinephrine are shown by modifying the two hydroxyl (phenolic) groups in positions 3 and 4 on the benzene ring, by chemically reacting the two groups with several acid moieties to form an ester bond with different alkyl chains. The addition of an alkyl group will enhance the lipophilicity of epinephrine (increase log P) and will consequently increase its permeability through the biological membranes (sublingual and buccal tissues in the oral cavity).
    Type: Application
    Filed: November 9, 2017
    Publication date: November 7, 2019
    Applicant: lono Pharma, LLC
    Inventor: Hassan Almoazen
  • Patent number: 10314771
    Abstract: An oral composition is provided comprising crosslinked polyvinylpyrrolidone (PVP) and xylitol. The xylitol and the crosslinked PVP are in a ratio of about 5:1, and the oral composition is in the form of a lozenge or lollipop. Methods are also provided.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: June 11, 2019
    Assignee: University of Tennessee Research Foundation
    Inventors: Mojdeh Dehghan, Daranee Versluis, Hassan Almoazen
  • Publication number: 20180256746
    Abstract: This invention relates to a pharmaceutical composition made of a clindamycin salt complexed with strongly acidic non-spherical resin particles, wherein predominantly all of the resin particles are less than 75 microns in diameter, to form clindamycin-resin complex, wherein in the clindamycin-resin complex provides for immediate release of the clindamycin in a target environment and at least one non-ionic excipient. In one embodiment, the inventive subject matter is an oral liquid pharmaceutical formulation made of a complex of clindamycin hydrochloride, a fractionated resin and excipients to stabilize the complex. The pharmaceutical formulation remains stable in deionized water until the dosage form reaches an ion-rich environment (stomach or intestine), there which the active ingredient clindamycin hydrochloride is released.
    Type: Application
    Filed: March 3, 2018
    Publication date: September 13, 2018
    Applicant: Iono Pharma, LLC
    Inventors: Hassan Almoazen, Baher Daihom, Alaadin Alayoubi
  • Publication number: 20180092817
    Abstract: An oral composition is provided comprising crosslinked polyvinylpyrrolidone (PVP) and xylitol. The xylitol and the crosslinked PVP are in a ratio of about 5:1, and the oral composition is in the form of a lozenge or lollipop. Methods are also provided.
    Type: Application
    Filed: December 6, 2017
    Publication date: April 5, 2018
    Inventors: Mojdeh Dehghan, Daranee Versluis, Hassan Almoazen
  • Publication number: 20150010598
    Abstract: Embodiments of the presently-disclosed subject matter include compositions that include iodine or salts thereof as well as methods administering the same to subjects in need thereof. In some embodiments the compositions comprise an aqueous solution, a surfactant, a cosurfactant, an oil, and iodine or salts thereof. The composition can be an emulsion. Methods for administration include topical administration, and in some embodiments the compositions can be administered transdermally by applying the composition directly to the skin of a subject. In some embodiments the compositions are topically administered with a spray applicator that dispenses a predetermined amount of the composition upon being actuated.
    Type: Application
    Filed: September 15, 2014
    Publication date: January 8, 2015
    Inventors: Hassan Almoazen, Hao Lou, Richard Helms, Catherine Crill