Patents by Inventor Heather R. Christofk

Heather R. Christofk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20240025895
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: September 1, 2023
    Publication date: January 25, 2024
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • Compositions and methods for modulating hair growth
    Patent number: 11787804
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Grant
    Filed: June 23, 2022
    Date of Patent: October 17, 2023
    Assignee: The Regents of the University of California
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • SMALL MOLECULE THERAPEUTICS FOR THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20230190736
    Abstract: This disclosure relates to methods of treating viral infections, such as influenza or coronavirus, with certain inhibitors, such as kinase inhibitors.
    Type: Application
    Filed: April 9, 2021
    Publication date: June 22, 2023
    Inventors: Vaithilingaraja Arumugaswami, Heather R. Christofk, Robert Damoiseaux, Gustavo Garcia, Peter Mullen, Brigitte N. Gomperts
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20230114220
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: June 23, 2022
    Publication date: April 13, 2023
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • Compositions and methods for modulating hair growth
    Patent number: 11472804
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Grant
    Filed: January 25, 2022
    Date of Patent: October 18, 2022
    Assignee: The Regents of the University of California
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20220153738
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: January 25, 2022
    Publication date: May 19, 2022
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • Compositions and methods for modulating hair growth
    Patent number: 11312714
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: April 26, 2022
    Assignee: The Regents of the University of California
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20220048908
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: December 30, 2019
    Publication date: February 17, 2022
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • Compositions and methods for promoting hair growth with Mpc1 inhibitors
    Patent number: 11213513
    Abstract: Provided herein are methods of accelerating, promoting, or restoring hair growth, comprising administering to a subject in need thereof an effective amount of a compound of formula (I). Also provided are compositions comprising the compound of formula (I).
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: January 4, 2022
    Assignee: The Regents of the University of California
    Inventors: William E. Lowry, Heather R. Christofk, Aimee Flores
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20200253917
    Abstract: The present disclosure relates to pharmaceutical compositions containing electron transport chain (ETC) inhibitors, which are capable of promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: September 28, 2018
    Publication date: August 13, 2020
    Inventors: William E. Lowry, Heather R. Christofk, Matilde Miranda, Aimee Flores
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20200157093
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: June 29, 2018
    Publication date: May 21, 2020
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu
  • COMPOSITIONS AND METHODS FOR PROMOTING HAIR GROWTH WITH MPC1 INHIBITORS
    Publication number: 20200030289
    Abstract: Provided herein are methods of accelerating, promoting, or restoring hair growth, comprising administering to a subject in need thereof an effective amount of a compound of formula (I). Also provided are compositions comprising the compound of formula (I).
    Type: Application
    Filed: August 25, 2017
    Publication date: January 30, 2020
    Inventors: William E. Lowry, Heather R. Christofk
  • Inhibitors of pyruvate kinase and methods of treating disease
    Patent number: 8877791
    Abstract: The invention provides pharmaceutical compositions, kits, and methods of treating cancer, diabetes, obesity, autoimmune disease, and benign prostatic hyperplasia using compounds that selectively inhibit pyruvate kinase M2 and an assay measuring chemical modulation of pyruvate kinase activity.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: November 4, 2014
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Lewis Cantley, Matthew G. Vander Heiden, Heather R. Christofk
  • Activators of pyruvate kinase M2 and methods of treating disease
    Patent number: 8552050
    Abstract: The invention described herein features methods, compositions, and kits for the use of activators of PKM2 for the treatment, prevention, or amelioration of diseases related to PKM2 function, including, e.g., cancer, diabetes, atherosclerosis, restenosis, obesity, autoimmune disorders, and proliferative disorders.
    Type: Grant
    Filed: August 18, 2008
    Date of Patent: October 8, 2013
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: Lewis C. Cantley, Matthew G. Vander Heiden, Heather R. Christofk
  • ACTIVATORS OF PYRUVATE KINASE M2 AND METHODS OF TREATING DISEASE
    Publication number: 20110046083
    Abstract: The invention described herein features methods, compositions, and kits for the use of activators of PKM2 for the treatment, prevention, or amelioration of diseases related to PKM2 function, including, e.g., cancer, diabetes, atherosclerosis, restenosis, obesity, autoimmune disorders, and proliferative disorders.
    Type: Application
    Filed: August 18, 2008
    Publication date: February 24, 2011
    Applicant: Beth Israel Deaconess Medical Center
    Inventors: Lewis C. Cantley, Matthew G. Vander Heiden, Heather R. Christofk
  • INHIBITORS OF PYRUVATE KINASE AND METHODS OF TREATING DISEASE
    Publication number: 20100099726
    Abstract: The invention provides pharmaceutical compositions, kits, and methods of treating cancer, diabetes, obesity, autoimmune disease, and benign prostatic hyperplasia using compounds that selectively inhibit pyruvate kinase M2 and an assay measuring chemical modulation of pyruvate kinase activity.
    Type: Application
    Filed: August 6, 2007
    Publication date: April 22, 2010
    Inventors: Lewis Cantley, Matthew Vander Heiden, Heather R. Christofk