Patents by Inventor Hedwich F. Kuipers

Hedwich F. Kuipers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200101042
    Abstract: Compositions for treating autoimmune, allergic, or atopic disease comprising a compound that inhibits hyaluronan synthesis and a pharmaceutically acceptable carrier are described. In some embodiments, the compound that inhibits hyaluronan synthesis is 4-methylumbelliferone or a metabolite of 4-methylumbelliferone. Methods for treating autoimmune diabetes, multiple sclerosis and/or autoimmune demyelination, including administering to the subject a composition having a compound in an amount effective to inhibit hyaluronan synthesis in a mammalian subject, are also described.
    Type: Application
    Filed: May 3, 2019
    Publication date: April 2, 2020
    Applicants: Benaroya Research Institute at Virginia Mason, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Paul L. Bollyky, Nadine Nagy, Thomas Wight, Hedwich F. Kuipers
  • Patent number: 10285976
    Abstract: Compositions for treating autoimmune, allergic, or atopic disease comprising a compound that inhibits hyaluronan synthesis and a pharmaceutically acceptable carrier are described. In some embodiments, the compound that inhibits hyaluronan synthesis is 4-methylumbelliferone or a metabolite of 4-methylumbelliferone. Methods for treating autoimmune diabetes, multiple sclerosis and/or autoimmune demyelination, including administering to the subject a composition having a compound in an amount effective to inhibit hyaluronan synthesis in a mammalian subject, are also described.
    Type: Grant
    Filed: August 12, 2014
    Date of Patent: May 14, 2019
    Assignees: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON
    Inventors: Paul L. Bollyky, Nadine Nagy, Thomas Wight, Hedwich F. Kuipers
  • Publication number: 20160184262
    Abstract: Compositions for treating autoimmune, allergic, or atopic disease comprising a compound that inhibits hyaluronan synthesis and a pharmaceutically acceptable carrier are described. In some embodiments, the compound that inhibits hyaluronan synthesis is 4-methylumbelliferone or a metabolite of 4-methylumbelliferone. Methods for treating autoimmune diabetes, multiple sclerosis and/or autoimmune demyelination, including administering to the subject a composition having a compound in an amount effective to inhibit hyaluronan synthesis in a mammalian subject, are also described.
    Type: Application
    Filed: August 12, 2014
    Publication date: June 30, 2016
    Applicants: Benaroya Research Institute at Virginia Mason, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Paul L. Bollyky, Nadine Nagy, Thomas Wight, Hedwich F. Kuipers