Patents by Inventor Heidi Lopez de Diego

Heidi Lopez de Diego has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9315459
    Abstract: Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine and salts thereof are provided, e.g., for the treatment of neuropathic pain.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: April 19, 2016
    Assignee: H. Lundbeck A/S
    Inventors: Benny Bang-Andersen, Andre Faldt, Tine Bryan Stensbol, Silke Miller, Heidi Lopez De Diego
  • Publication number: 20160083359
    Abstract: 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.
    Type: Application
    Filed: November 23, 2015
    Publication date: March 24, 2016
    Inventors: Benny Bang-Andersen, André Faldt, Arne Mørk, Heidi Lopez De Diego, René Holm, Tine Bryan Stensbøl, Lone Munch Ringgard, Michael J. Mealy, Michael Harold Rock, Jørgen Brodersen, Morten Jørgensen, Nicholas Moore
  • Patent number: 9227946
    Abstract: 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: January 5, 2016
    Assignee: H. Lundbeck A/S
    Inventors: Andre Faldt, Rene Holm, Heidi Lopez de Diego
  • Patent number: 9125909
    Abstract: This disclosure relates to 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine or a pharmaceutically acceptable salt thereof in a crystalline form.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: September 8, 2015
    Assignee: H. Lundbeck A/S
    Inventors: Benny Bang-Andersen, Andre Faldt, Arne Mork, Heidi Lopez de Diego, Rene Holm, Tine Bryan Stensbol
  • Patent number: 9125908
    Abstract: 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: September 8, 2015
    Assignee: H. Lundbeck A/S
    Inventors: Benny Bang-Andersen, Arne Mork, Tine Bryan Stensbol, Andre Faldt, Rene Holm, Heidi Lopez de Diego
  • Publication number: 20150094316
    Abstract: Liquid formulations of lactic acid addition salts of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine are provided
    Type: Application
    Filed: December 11, 2014
    Publication date: April 2, 2015
    Inventors: Svend Treppendahl, Heidi Lopez De Diego
  • Publication number: 20150073018
    Abstract: Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine and salts thereof are provided, e.g., for the treatment of neuropathic pain.
    Type: Application
    Filed: November 14, 2014
    Publication date: March 12, 2015
    Inventors: Benny Bang-Andersen, Andre Faldt, Tine Bryan Stensbol, Silke Miller, Heidi Lopez De Diego
  • Patent number: 8969355
    Abstract: This disclosure relates to a method of treating a disease selected from the group consisting of affective disorders, depression, major depressive disorder, anxiety, general anxiety disorder, social anxiety disorder, obsessive compulsive disorder, panic disorder, and panic attacks. The method includes administering a therapeutically effective amount of Compound I or a pharmaceutically acceptable salt thereof to a patient in need thereof, in which Compound I is 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine.
    Type: Grant
    Filed: September 9, 2014
    Date of Patent: March 3, 2015
    Assignee: H. Lundbeck A/S
    Inventors: Benny Bang-Andersen, Andre Faldt, Rene Holm, Heidi Lopez de Diego
  • Patent number: 8940746
    Abstract: Liquid formulations of lactic acid addition salts of 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piper-azine are provided.
    Type: Grant
    Filed: April 16, 2010
    Date of Patent: January 27, 2015
    Assignee: H. Lundbeck A/S
    Inventors: Svend Treppendahl, Heidi Lopez De Diego
  • Publication number: 20140315921
    Abstract: This disclosure relates to 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine or a pharmaceutically acceptable salt thereof in a crystalline form.
    Type: Application
    Filed: July 9, 2014
    Publication date: October 23, 2014
    Inventors: Benny Bang-Andersen, Andre Faldt, Arne Mork, Heidi Lopez de Diego, Rene Holm, Tine Bryan Stensbol, Nicholas Moore
  • Patent number: 8754217
    Abstract: The present invention relates to the Nalmefene hydrochloride dihydrate, methods of manufacturing Nalmefene hydrochloride dihydrate, a pharmaceutical composition comprising Nalmefene hydrochloride dihydrate and a method of treatment comprising administering Nalmefene hydrochloride dihydrate.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: June 17, 2014
    Assignee: H. Lundbeck A/S
    Inventors: Heidi Lopez de Diego, Carla De Faveri, Florian Anton Martin Huber
  • Patent number: 8729065
    Abstract: Described are crystalline forms of the pharmaceutical compound “[9S-(9?,10?,12?)]-5,16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3?,2?,1?-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester”, as well as methods for their use and preparation.
    Type: Grant
    Filed: January 3, 2011
    Date of Patent: May 20, 2014
    Assignee: Cephalon, Inc.
    Inventors: Michael Harold Rock, Heidi Lopez De Diego, Kim Lasse Christensen, Ole Nielsen, Anders Buur, Mark Howells
  • Patent number: 8722684
    Abstract: 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.
    Type: Grant
    Filed: June 15, 2007
    Date of Patent: May 13, 2014
    Assignee: H. Lundbeck A/S
    Inventors: Benny Bang-Andersen, Andre Faldt, Arne Mork, Heidi Lopez de Diego, Rene Holm, Tine Bryan Stensbol, Nicholas Moore
  • Publication number: 20130338365
    Abstract: The present invention relates to the Nalmefene hydrochloride dihydrate, methods of manufacturing Nalmefene hydrochloride dihydrate, a pharmaceutical composition comprising Nalmefene hydrochloride dihydrate and a method of treatment comprising administering Nalmefene hydrochloride dehydrate.
    Type: Application
    Filed: June 25, 2013
    Publication date: December 19, 2013
    Inventors: Heidi Lopez de DIEGO, Carla de FAVERI, Florian Anton Martin HUBER
  • Patent number: 8598348
    Abstract: The present invention concerns a process for the manufacture of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: December 3, 2013
    Assignee: H. Lundbeck A/S
    Inventors: Henrik Vigan Nicolajsen, Heidi Lopez de Diego, Michael Harold Rock
  • Patent number: 8530495
    Abstract: The present invention relates to the Nalmefene hydrochloride dihydrate, methods of manufacturing Nalmefene hydrochloride dihydrate, a pharmaceutical composition comprising Nalmefene hydrochloride dihydrate and a method of treatment comprising administering Nalmefene hydrochloride dihydrate.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: September 10, 2013
    Assignees: H. Lundbeck A/S, Bioei Therapies Corp
    Inventors: Heidi Lopez de Diego, Carla de Faveri, Florian Anton Martin Huber
  • Patent number: 8450324
    Abstract: Crystalline base of compound trans-1-((1R,3S)-6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine, processes for the preparation of purified free base or salts of this compound, pharmaceutical compositions comprising the base and medical use thereof, including for treatment of schizophrenia and other psychotic disorders.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: May 28, 2013
    Assignee: H. Lunbeck A/S
    Inventors: Benny Bang-Andersen, Heidi Lopez de Diego
  • Patent number: 8299095
    Abstract: Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine and salts thereof are provided e.g. for the treatment of neuropathic pain.
    Type: Grant
    Filed: June 15, 2007
    Date of Patent: October 30, 2012
    Assignee: H. Lundbeck A/S
    Inventors: Benny Bang-Andersen, Andre Faldt, Tine Bryan Stensbol, Silke Miller, Heidi Lopez De Diego
  • Patent number: 8227607
    Abstract: Methods for the preparation of 4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and salts thereof are described.
    Type: Grant
    Filed: June 22, 2010
    Date of Patent: July 24, 2012
    Assignee: H. Lundbeck A/S
    Inventors: Heidi Lopez de Diego, Ole Nielsen, Lone Munch Ringgard, Henrik Svane, Allan Carsten Dahl, Mark Howells, Benny Bang-Andersen, Lars Ole Lyngsø, Sherry Lynn Collier
  • Publication number: 20120165325
    Abstract: Polymorphic forms of N-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide are provided together with a process for the manufacture of said compound.
    Type: Application
    Filed: March 2, 2012
    Publication date: June 28, 2012
    Applicant: H. Lundbeck A/S
    Inventors: Svend Treppendahl, Karin Liltorp, Heidi Lopez de Diego