Patents by Inventor Heidi Lopez de Diego

Heidi Lopez de Diego has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120035188
    Abstract: Liquid formulations of lactic acid addition salts of 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine are provided.
    Type: Application
    Filed: April 16, 2010
    Publication date: February 9, 2012
    Applicant: H. LUNDBECK A/S
    Inventors: Svend Treppendahl, Heidi Lopez De Diego
  • Publication number: 20120004409
    Abstract: The present invention concerns a process for the manufacture of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine.
    Type: Application
    Filed: February 16, 2010
    Publication date: January 5, 2012
    Applicant: H. LUNDBECK A/S
    Inventors: Henrik Vigan Nicolajsen, Heidi Lopez de Diego, Michael Harold Rock
  • Patent number: 8076320
    Abstract: Described are crystalline forms of the pharmaceutical compound “[9S-(9?,10?,12?)]-5,16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9, 12-epoxy-1H-diindolo[1,2,3-fg:3?,2?,1?-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester”, as well as methods for their use and preparation.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: December 13, 2011
    Assignee: Cephalon, Inc.
    Inventors: Michael Harold Rock, Heidi Lopez De Diego, Kim Lasse Christensen, Ole Nielsen, Anders Buur, Mark Howells
  • Patent number: 8076342
    Abstract: 4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine hydrogen malonate salt and pharmaceutical comprising and uses of the same, including for the treatment of schizophrenia and other psychotic disorders are described.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: December 13, 2011
    Inventors: Heidi Lopez de Diego, Ole Nielsen, Lone Munch Ringgard, Henrik Svane, Allan Carsten Dahl, Mark Howells, Benny Bang-Andersen, Lars Ole Lyngso
  • Publication number: 20110251228
    Abstract: The present invention relates to the Nalmefene hydrochloride dihydrate, methods of manufacturing Nalmefene hydrochloride dihydrate, a pharmaceutical composition comprising Nalmefene hydrochloride dihydrate and a method of treatment comprising administering Nalmefene hydrochloride dehydrate.
    Type: Application
    Filed: December 4, 2009
    Publication date: October 13, 2011
    Applicants: Biotie Therapies Corp., H. Lundbeck A/S
    Inventors: Heidi Lopez de Diego, Carla de Faveri, Florian Anton Martin Huber
  • Publication number: 20110124629
    Abstract: Described are crystalline forms of the pharmaceutical compound “[9S-(9?,10?,12?)]-5,16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3 -fg:3?,2?,1?-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester”, as well as methods for their use and preparation.
    Type: Application
    Filed: January 3, 2011
    Publication date: May 26, 2011
    Applicant: CEPHALON, INC.
    Inventors: Michael Harold Rock, Heidi Lopez De Diego, Kim Lasse Christensen, Ole Nielsen, Anders Buur, Mark Howells
  • Publication number: 20110053957
    Abstract: 4-((1R,35)-6-Chloro-3 -phenylindan-1-yl)-1,2,2-trimethylpiperazine hydrogen malonate salt and pharmaceutical comprising and uses of the same, including for the treatment of schizophrenia and other psychotic disorders are described.
    Type: Application
    Filed: November 4, 2010
    Publication date: March 3, 2011
    Applicant: H. LUNDBECK A/S
    Inventors: Heidi Lopez de Diego, Ole Nielsen, Lone Munch Ringgard, Henrik Svane, Allan Carsten Dahl, Mark Howells, Benny Bang-Andersen, Lars Ole Lyngsø
  • Publication number: 20100324291
    Abstract: Methods for the preparation of 4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and salts thereof are described.
    Type: Application
    Filed: June 22, 2010
    Publication date: December 23, 2010
    Applicant: H. LUNDBECK A/S
    Inventors: Heidi Lopez de Diego, Ole Nielsen, Lone Munch Ringgard, Henrik Svane, Allan Carsten Dahl, Mark Howells, Benny Bang-Andersen, Lars Ole Lyngsø, Sherry Lynn Collier
  • Publication number: 20100297240
    Abstract: 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.
    Type: Application
    Filed: June 15, 2007
    Publication date: November 25, 2010
    Applicant: H. Lundbeck A/S
    Inventors: Benny Bang-Andersen, Andre Faldt, Arne Mork, Heidi Lopez De Diego, Rene Holm, Tine Bryan Stensbol, Lone Munch Ringgaard, Michael J. Mealy, Michael Harold Rock, Jorgen Brodersen, Morten Jorgensen, Nicholas Moore
  • Publication number: 20100286138
    Abstract: Polymorphic forms of N-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide are provided together with a process for the manufacture of said compound.
    Type: Application
    Filed: May 11, 2010
    Publication date: November 11, 2010
    Applicant: H. LUNDBECK A/S
    Inventors: Svend Treppendahl, Karin Liltorp, Heidi Lopez de Diego
  • Patent number: 7767683
    Abstract: 4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine hydrogen succinate, pharmaceutical compositions containing the salt and the medical use thereof, including for the treatment of schizophrenia and other psychotic disorders. Also described are methods for the preparation of 4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and medical uses thereof.
    Type: Grant
    Filed: August 18, 2004
    Date of Patent: August 3, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Heidi Lopez de Diego, Ole Nielsen, Lone Munch Ringgard, Henrik Svane, Allan Carsten Dahl, Mark Howells, Benny Bang-Andersen, Lars Ole Lyngso, Sherry Lynn Collier
  • Publication number: 20100105730
    Abstract: Liquid formulations of the DL-lactic acid, the glutaric acid, the L-aspartic acid and the glutamic acid salts of 4-[2-(4-methylphenylsulfanyl)phenyl]piperidine and their use in the manufacture of a medicament to be used in the treatment of CNS diseases are provided.
    Type: Application
    Filed: March 14, 2008
    Publication date: April 29, 2010
    Applicant: H. Lundbeck A/S
    Inventors: Gudrun Lasskogen, Tine Bryan Stensbol, Heidi Lopez de Diego
  • Publication number: 20100105699
    Abstract: Crystalline base of compound trans-1-(1R,3S)-6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine, processes for the preparation of purified free base or salts of this compound, pharmaceutical compositions comprising the base and medical use thereof, including for treatment of schizophrenia and other psychotic disorders.
    Type: Application
    Filed: December 1, 2009
    Publication date: April 29, 2010
    Applicant: H. Lundbeck A/S
    Inventors: Benny Bang-Andersen, Heidi Lopez de Diego
  • Patent number: 7648991
    Abstract: Crystalline base of compound trans-1-((1R,3S)-6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine, processes for the preparation of purified free base or salts of this compound, pharmaceutical compositions comprising the base and medical use thereof, including for treatment of schizophrenia and other psychotic disorders.
    Type: Grant
    Filed: February 14, 2006
    Date of Patent: January 19, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Benny Bang-Andersen, Heidi Lopez de Diego
  • Publication number: 20090264465
    Abstract: Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine and salts thereof are provided e.g. for the treatment of neuropathic pain.
    Type: Application
    Filed: June 15, 2007
    Publication date: October 22, 2009
    Applicant: H. LUNDBECK A/S
    Inventors: Benny Bang-Andersen, Andre Faldt, Tine Bryan Stensbol, Silke Miller, Heidi Lopez De Diego
  • Publication number: 20080269248
    Abstract: A tartrate and malate salt of trans-1-(6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine, in particular for medical use, pharmaceutical formulations thereof, including for treatment of schizophrenia or other diseases involving psychotic symptoms.
    Type: Application
    Filed: February 14, 2006
    Publication date: October 30, 2008
    Applicant: H. Lundbeck A/S
    Inventors: Ole Nielsen, Heidi Lopez de Diego, Benny Bang-Andersen
  • Publication number: 20080153848
    Abstract: Crystalline base of compound trans-1-((1R,3S)-6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine, processes for the preparation of purified free base or salts of this compound, pharmaceutical compositions comprising the base and medical use thereof, including for treatment of schizophrenia and other psychotic disorders.
    Type: Application
    Filed: February 14, 2006
    Publication date: June 26, 2008
    Applicant: H. Lundbeck A/S
    Inventors: Benny Bang-Andersen, Heidi Lopez De Diego
  • Publication number: 20070191339
    Abstract: Described are crystalline forms of the pharmaceutical compound “[9S-(9?,10?,12?)]-5,16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9, 12-epoxy-1H-diindolo[1,2,3-fg:3?,2?,1?-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester”, as well as methods for their use and preparation.
    Type: Application
    Filed: February 24, 2005
    Publication date: August 16, 2007
    Applicant: H. Lundbeck A/S
    Inventors: Michael Rock, Heidi Lopez De Diego, Kim Christensen, Ole Nielsen, Anders Buur, Mark Howells
  • Publication number: 20050171135
    Abstract: The present invention relates to a hydrohalogenide of 1?-[4-[1-(4-fluorophenyl)-1H-indole-3-yl]-1-butyl]-spiro[isobenzofuran-1(3H),4?-piperidine], pharmaceutical compositions containing the acid addition salts and the use thereof for the treatment of psychic and neurological disorders.
    Type: Application
    Filed: December 13, 2004
    Publication date: August 4, 2005
    Applicant: H. Lundbeck A/S
    Inventors: Niels Mork, Heidi Lopez de Diego, Ole Nielsen
  • Patent number: 6844352
    Abstract: The present invention relates to a hydrohalogenide of 1?-[4-[1-(4-fluorophenyl)-1H-indole-3-yl]-1-butyl]-spiro[isobenzofuran-1(3H),4?-piperidine], pharmaceutical compositions containing the acid addition salts and the use thereof for the treatment of psychic and neurological disorders.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: January 18, 2005
    Assignee: H. Lundbeck A/S
    Inventors: Niels Mørk, Heidi Lopez de Diego, Ole Nielsen