Patents by Inventor Heiko Schirmer

Heiko Schirmer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metal chelates having a perfluorinated PEG radical, processes for their preparation, and their use
    Patent number: 8263040
    Abstract: The invention relates to the subjects characterized in the patent claims, namely metal chelates having a perfluorinated PEG radical, processes for their preparation, and their use, processes for their preparation and their use in NMR and X-ray diagnosis, radiodiagnosis and radiotherapy, and in MRT lymphography.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: September 11, 2012
    Assignee: Bayer Schering Pharma AG
    Inventors: Johannes Platzek, Heiko Schirmer, Hanns-Joachim Weinmann, Bernd Misselwitz, Ludwig Zorn
  • Perfluoroalkyl-Containing Complexes, Process For Their Production As Well As Their Use
    Publication number: 20090297454
    Abstract: The invention relates to the subjects that are characterized in the claims, namely perfluoroalkyl-containing metal complexes with nitrogen-containing radicals of general formula I, process for their production and their use in NMR and x-ray diagnosis, radiodiagnosis, and radiotherapy, as well as in MRT lymphography and in blood-pool imaging.
    Type: Application
    Filed: May 20, 2009
    Publication date: December 3, 2009
    Inventors: Heiko SCHIRMER, Hanns-Joachim Weinmann, Johannes Platzek, Ludwig Zorn, Bernd Misselwitz, Joerg Meding, Heribert Schmitt-Willich, Thomas Brumby
  • Perfluoroalkyl-containing complexes, process for their production as well as their use
    Patent number: 7618957
    Abstract: The invention relates to the subjects that are characterized in the claims, namely perfluoroalkyl-containing metal complexes with nitrogen-containing radicals of general formula I, process for their production and their use in NMR and x-ray diagnosis, radiodiagnosis, and radiotherapy, as well as in MRT lymphography and in blood-pool imaging.
    Type: Grant
    Filed: July 17, 2006
    Date of Patent: November 17, 2009
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Heiko Schirmer, Hanns-Joachim Weinmann, Johannes Platzek, Ludwig Zorn, Bernd Misselwitz, Joerg Meding, Heribert Schmitt-Willich, Thomas Brumby
  • NOVEL CASCADE POLYMER COMPLEXES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
    Publication number: 20080213187
    Abstract: The invention relates to novel cascade polymer complexes, to compositions comprising these compounds, to the use of the complexes in NMR diagnosis, and to processes for preparing these compounds and compositions.
    Type: Application
    Filed: January 17, 2008
    Publication date: September 4, 2008
    Inventors: Heribert SCHMITT-WILLICH, Heiko Schirmer, Bernd Misselwitz, Hanns-Joachim Weinmann, Peter Caravan
  • METAL CHELATES HAVING A PERFLUORINATED PEG RADICAL, PROCESSES FOR THEIR PREPARATION, AND THEIR USE
    Publication number: 20080159954
    Abstract: The invention relates to the subjects characterized in the patent claims, namely metal chelates having a perfluorinated PEG radical, processes for their preparation, and their use, processes for their preparation and their use in NMR and X-ray diagnosis, radiodiagnosis and radiotherapy, and in MRT lymphography.
    Type: Application
    Filed: October 17, 2007
    Publication date: July 3, 2008
    Inventors: Johannes Platzek, Heiko Schirmer, Hanns-Joachim Weinmann, Bernd Misselwitz, Ludwig Zorn
  • Trimeric, macrocyclically substituted halo-benzene derivatives
    Patent number: 7385054
    Abstract: The metal complexes of general formula I in which Hal stands for bromine or iodine, and A1 and A2 have different meanings, are suitable as contrast media.
    Type: Grant
    Filed: November 14, 2005
    Date of Patent: June 10, 2008
    Assignee: Schering AG
    Inventors: Johannes Platzek, Heiko Schirmer, Hanns-Joachim Weinmann, Jose Luis Martin, Juan R. Harto
  • Process for the production of triiodotrimesic acid
    Patent number: 7355067
    Abstract: A new process for the production of triiodotrimesic acid that is used as an intermediate product for the synthesis of x-ray contrast media is described.
    Type: Grant
    Filed: December 1, 2006
    Date of Patent: April 8, 2008
    Assignee: Schering AG
    Inventors: Heiko Schirmer, Hannelore Niedballa, legal representative, Johannes Platzek, Jose Luis Martin, Juan R. Harto, Jose Carretero, Ulrich Niedballa
  • Perfluoroalkyl-containing complexes, process for their production as well as their use
    Publication number: 20070189969
    Abstract: The invention relates to the subjects that are characterized in the claims, namely perfluoroalkyl-containing metal complexes with nitrogen-containing radicals of general formula I, process for their production and their use in NMR and x-ray diagnosis, radiodiagnosis, and radiotherapy, as well as in MRT lymphography and in blood-pool imaging.
    Type: Application
    Filed: July 17, 2006
    Publication date: August 16, 2007
    Inventors: Heiko Schirmer, Hanns-Joachim Weinmann, Johannes Platzek, Ludwig Zorn, Bernd Misselwitz, Joerg Meding, Heribert Schmitt-Willich, Thomas Brumby
  • Process for the production of triiodotrimesic acid
    Publication number: 20070093674
    Abstract: A new process for the production of triiodotrimesic acid that is used as an intermediate product for the synthesis of x-ray contrast media is described.
    Type: Application
    Filed: December 1, 2006
    Publication date: April 26, 2007
    Inventors: Heiko Schirmer, Ulrich Niedballa, Hannelore Niedballa, Johannes Platzek, Jose Martin, Juan Harto, Jose Carretero
  • Trimeric macrocyclic substituted benzene derivatives
    Patent number: 7208140
    Abstract: The metal complexes of general formula I in which Hal stands for bromine or iodine and A1 and A2 have different meanings, are suitable as contrast media.
    Type: Grant
    Filed: February 19, 2004
    Date of Patent: April 24, 2007
    Assignee: Schering Aktiengesellschaft
    Inventors: Heiko Schirmer, Hanns-Joachim Weinmann, Johannes Platzek, Jose Luis Martin, Juan R. Harto, Bjoern Riefke
  • Perfluoroalkyl-containing complexes, process for their production as well as their use
    Publication number: 20070020183
    Abstract: The invention relates to the subjects that are characterized in the claims, namely perfluoroalkyl-containing metal complexes with an N-alkyl group of general formula 1, process for their production and their use in NMR and x-ray diagnosis, radiodiagnosis, and radiotherapy, as well as in MRT lymphography.
    Type: Application
    Filed: July 14, 2006
    Publication date: January 25, 2007
    Inventors: Heiko Schirmer, Hanns-Joachim Weinmann, Johannes Platzek, Ludwig Zorn, Bernd Misselwitz, Joerg Meding, Heribert Schmitt-Willich, Thomas Brumby
  • Process for the production of triiodotrimesic acid
    Patent number: 7166740
    Abstract: A new process for the production of triiodotrimesic acid that is used as an intermediate product for the synthesis of x-ray contrast media is described.
    Type: Grant
    Filed: July 14, 2004
    Date of Patent: January 23, 2007
    Assignee: Schering AG
    Inventors: Heiko Schirmer, Ulrich Niedballa, Hannelore Niedballa, Johannes Platzek, Jose Luis Martin, Juan R. Harto, Jose Carretero
  • Conjugates of macrocyclic metal complexes with biomolecules and their use for the production of agents for NMR diagnosis and radiodiagnosis as well as radiotherapy
    Publication number: 20070014725
    Abstract: The invention relates to conjugates that consist of macrocyclic metal complexes with biomolecules and their production. The conjugates are suitable as contrast media in NMR diagnosis and radiodiagnosis as well as as agents for radiotherapy. High relaxivity is achieved by a special liganding of macrocyclic compounds, and a fine-tuning of the relaxivity is made possible.
    Type: Application
    Filed: March 28, 2006
    Publication date: January 18, 2007
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Gunther Michl, Thomas Frenzel, Detlev Sulzle, Hans Bauer, Bernd Raduchel, Hanns-Joachim Weinmann, Heiko Schirmer
  • Macrocyclic metal complexes and their use for the production of conjugates with biomolecules
    Patent number: 7164016
    Abstract: The invention relates to macrocyclic metal complexes and their production and use for the production of conjugates with biomolecules. The conjugates are suitable as contrast media in NMR diagnosis and radiodiagnosis as well as for radiotherapy. High relaxivity is achieved by a special liganding of macrocyclic compounds, and a fine-tuning of the relaxivity is made possible.
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: January 16, 2007
    Assignee: Schering AG
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Günther Michl, Thomas Frenzel, Detlev Sülzle, Hans Bauer, Bernd Radüchel, Hanns-Joachim Weinmann, Heiko Schirmer
  • Macrocyclic metal complexes and their use for the production of conjugates with biomolecules
    Publication number: 20070009442
    Abstract: The invention relates to macrocyclic metal complexes and their production and use for the production of conjugates with biomolecules. The conjugates are suitable as contrast media in NMR diagnosis and radiodiagnosis as well as for radiotherapy. High relaxivity is achieved by a special liganding of macrocyclic compounds, and a fine-tuning of the relaxivity is made possible.
    Type: Application
    Filed: March 28, 2006
    Publication date: January 11, 2007
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Gunther Michl, Thomas Frenzel, Detlev Sulzle, Hans Bauer, Bernd Raduchel, Hanns-Joachim Weinmann, Heiko Schirmer
  • Hydroxypyridinone derivatives, metal complexes thereof and the use thereof for preparing conjugates with biomolecules
    Publication number: 20070003484
    Abstract: The invention relates to hydroxypyridinone derivatives, their metal complexes, their preparation and their use for preparing conjugates with biomolecules. The conjugates are suitable as contrast agents in NMR diagnosis. A high relaxivity is achieved and the NMRD maximum is raised through a specific design of the ligands.
    Type: Application
    Filed: December 20, 2005
    Publication date: January 4, 2007
    Inventors: Heribert Schmitt-Willich, Heiko Schirmer, Johannes Platzek, Stephane Dumas, Vincent Jacques, Thomas Brumby, Detlev Suelzle, Bernd Misselwitz
  • Conjugates of hydroxypyridinone derivative metal complexes with biomolecules and their use for MRI diagnosis
    Publication number: 20060292079
    Abstract: The invention relates to conjugates of hydroxypyridinone derivative metal complexes and to their preparation. The conjugates are suitable as contrast agents in NMR diagnosis. A high relaxivity is achieved and the NMRD maximum is raised through a specific design of the ligands.
    Type: Application
    Filed: December 20, 2005
    Publication date: December 28, 2006
    Inventors: Heribert Schmitt-Willich, Heiko Schirmer, Johannes Platzek, Stephane Dumas, Vincent Jacques, Thomas Brumby, Detlev Suelzle, Bernd Misselwitz
  • Pharmaceutical agents that contain fluoroalkyl-containing metal complexes and epothilones
    Publication number: 20060257322
    Abstract: The invention relates to pharmaceutical agents that contain at least one fluoroalkyl-containing metal complex that has a critical micelle-formation concentration of <10?3 mol/l and a hydrodynamic micelle diameter (2Rh) of >1 nm, and at least one natural or synthetic epothilone or epothilone derivative, optionally with the additives that are commonly used in galenicals.
    Type: Application
    Filed: February 16, 2006
    Publication date: November 16, 2006
    Inventors: Ruediger Lawaczeck, Rolf Press, Katja Schoen, Jens Hoffmann, Ulirch Klar, Bernd Misselwitz, Johannes Platzek, Heiko Schirmer
  • Process for the production of triiodotrimesic acid
    Patent number: 7083516
    Abstract: A new process for the production of triiodotrimesic acid that is used as an intermediate product for the synthesis of x-ray contrast media is described.
    Type: Grant
    Filed: July 14, 2004
    Date of Patent: August 1, 2006
    Assignee: Schering AG
    Inventors: Johannes Platzek, Ulrich Niedballa, Heiko Schirmer, Heinz Gries
  • Trimeric, macrocyclically substituted halo-benzene derivatives
    Publication number: 20060154989
    Abstract: The metal complexes of general formula I in which Hal stands for bromine or iodine, and A1 and A2 have different meanings, are suitable as contrast media.
    Type: Application
    Filed: November 14, 2005
    Publication date: July 13, 2006
    Inventors: Johannes Platzek, Heiko Schirmer, Hanns-Joachim Weinmann, Jose Luis Martin, Juan Harto