Abstract: The invention relates inter alia to methods of producing sulfated oligosaccharide derivatives and intermediates thereof. The sulfated oligosaccharide derivatives may be represented by the following formula (I): [X]nY?ZR1R2Formula (I) wherein: X and Y are any D- or L-hexose or pentose, wherein each hydroxyl group not involved in a glycosidic linkage is substituted by a group W, and Y has an anomeric carbon atom; W is SO3M, and M is any pharmaceutically acceptable cation; n is an integer from 2 to 6; Z is O, and is linked to the anomeric carbon atom of Y; and R1R2 together form a lipophilic moiety.

Abstract: A facial cold compress assembly for reducing facial swelling includes a strip that has a pair of pouches each being integrated into the strip. The strip is wearable on a user's face having the strip extending across the user's nose and beneath each of the user's eyes. In this way the strip is aligned with the user's nasal pathways. The strip is comprised of a thermally conductive material such that the strip is in thermal communication with the user's face when the strip is worn. An adhesive layer is bonded to the strip to retain the strip on the user's face. A pair of thermal packs is each removably positionable into a respective one of the pouches. Each of the thermal packs is positionable in a refrigerator for chilling and subsequently reducing swelling on the user's face and reduce congestion in the user's nasal pathways when the strip is worn.

Abstract: Antibodies and antigen-binding fragments of antibodies that bind GCC are disclosed. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein.

Abstract: Antibodies and antigen-binding fragments of antibodies that bind GCC are disclosed. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein.

Abstract: The invention provides a method for chemically activating vitamin D compounds to obtain active rodenticidal preparations.The activated vitamin D preparation offers an effective and relatively inexpensive rodenticidal material.

Abstract: A rodenticide suitable for the control of rat and mice populations containing as the active rodenticidal ingredient 1.alpha.-hydroxycholecalciferol or 1.alpha.-hydroxyergocalciferol or 1,25-dihydroxycholecalciferol.