Patents by Inventor Henricus Johannes Franciscus Maas

Henricus Johannes Franciscus Maas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of estrone and/or estradiol-derivatives
    Patent number: 8273908
    Abstract: Process for the preparation of a compound of general formula (II) wherein R1 and R2 independently are hydrogen or a hydroxy- or hydrocarbyl group; or wherein R1 and R2 together are a double bonded oxygen; R3 is hydrogen; R?4 is a nitrobenzophenone group; and R5 and R6 independently are hydrogen or a hydroxy- or hydrocarbyl group; from a compound of general formula (I) wherein, R1, R2 R3, R5 and R6 are as defined above and R4 is hydrogen; wherein the compound of formula (I) is reacted under alkaline conditions with 2-chloro-5-nitrobenzophenone in the presence of an alkanolic solvent and the compound of formula (II) is directly crystallized from this alkanolic solvent. Complex of an alkanol and a compound of general formula (II) obtainable from the above process and processes wherein the above process or complex are used.
    Type: Grant
    Filed: August 22, 2005
    Date of Patent: September 25, 2012
    Assignee: MSD Oss B.V.
    Inventors: Lambertus Gerardus Maria Willems, Henricus Johannes Franciscus Maas, Martin Ostendorf