Abstract: The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to a ligand and may improve immunotherapy by limiting side effects associated with immunotherapy.

Abstract: The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to an NKG2D ligand or PD1 ligand and may improve immunotherapy by limiting side effects associated with immunotherapy. The present disclosure also encompasses compositions and methods for recruiting cytotoxic lymphocytes to target cells using NKG2D receptor ligands or PD1 ligands. The compositions disclosed herein comprise a NKG2D receptor ligand and a targeting molecule and may improve immunotherapy by limiting side effects associated with immunotherapy.

Abstract: The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to a ligand and may improve immunotherapy by limiting side effects associated with immunotherapy.

Abstract: The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to an NKG2D ligand or PD1 ligand and may improve immunotherapy by limiting side effects associated with immunotherapy. The present disclosure also encompasses compositions and methods for recruiting cytotoxic lymphocytes to target cells using NKG2D receptor ligands or PD1 ligands. The compositions disclosed herein comprise a NKG2D receptor ligand and a targeting molecule and may improve immunotherapy by limiting side effects associated with immunotherapy.

Abstract: The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to an NKG2D ligand or PD1 ligand and may improve immunotherapy by limiting side effects associated with immunotherapy. The present disclosure also encompasses compositions and methods for recruiting cytotoxic lymphocytes to target cells using NKG2D receptor ligands or PD1 ligands. The compositions disclosed herein comprise a NKG2D receptor ligand and a targeting molecule and may improve immunotherapy by limiting side effects associated with immunotherapy.

Abstract: The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to a ligand and may improve immunotherapy by limiting side effects associated with immunotherapy.

Abstract: The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to a ligand and may improve immunotherapy by limiting side effects associated with immunotherapy.

Abstract: The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to an NKG2D ligand or PD1 ligand and may improve immunotherapy by limiting side effects associated with immunotherapy. The present disclosure also encompasses compositions and methods for recruiting cytotoxic lymphocytes to target cells using NKG2D receptor ligands or PD1 ligands. The compositions disclosed herein comprise a NKG2D receptor ligand and a targeting molecule and may improve immunotherapy by limiting side effects associated with immunotherapy.

Abstract: The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to a ligand and may improve immunotherapy by limiting side effects associated with immunotherapy.

Abstract: An apparatus and method for dewatering sludges and the like as part of landfill operations by electrokinetic techniques including placing anode and cathode electrode modules in contact with the sludge and applying electrical energy to the electrodes to establish an electric field in the sludge. Charged particles within the sludge, including macro-molecules, colloids, and suspended particles, electrophoretically migrate to the oppositely charged counter electrode and consolidate. A filtration media located at one of the electrodes permits the electro-osmotic removal of water from the sludge to encourage solids densification. The electrical energy applied to the electrodes is a chopped, time-varying, intermittent unidirectional current having a rapid rise edge which provides dewatering results comparable to prior methods that used direct current or full AC current but at substantially reduced energy consumption to provide more economical dewatering.

Abstract: A process for cleaning fouled separation membranes such as ultrafiltration, reverse osmosis, and microfiltration membranes is provided comprising: removing a separation membrane having a fouled surface from operation; effecting reaction on the fouled surface of said membrane of an inorganic peroxide and an alkali metal or alkaline earth metal hypohalite; and thereafter, substantially removing the foulant and the reaction products thereof from the membrane surface.

Abstract: An apparatus and method for dewatering sludges and the like as part of landfill operations by electrokinetic techniques including placing anode and cathode electrode modules in contact with the sludge and applying electrical energy to the electrodes to establish an electric field in the sludge. Charged particles within the sludge, including macro-molecules, colloids, and suspended particles, elecrophoretically migrate to the oppositely charged counter electrode and consolidate. A filtration media located at one of the electrodes permits the electro-osmotic removal of water from the sludge to encourage solids densification. The electrical energy applied to the electrodes is a chopped, time-varying, intermittent unidirectional current having a rapid rise edge which provides dewatering results comparable to prior methods that used direct current or full AC current but at substantially reduced energy consumption to provide more economical dewatering.

Abstract: The present invention relates to a novel cellulosic wood pulp fiber having lower specific volume for a given surface area than conventionally prepared wood pulp fibers, to products made therefrom, and to the process of making such fiber comprising hydrating cellulosic wood pulp fiber to a freeness of at least about 650 CSF and lower, freezing the fibers while in an aqueous slurry containing at least 40% water to a fiber temperature of at least -5.degree. C. or below, and thawing the pulp fibers to a temperature at which they will flow.

Abstract: A process of making polyethylene pellets from polyethylene broke comprising forming a polyethylene solvent-free aqueous slurry of said broke and defibering said slurry to produce a polyethylene slurry having a fiber to solid polyethylene ratio of no more 1:20, dehydrating said polyethylene slurry to less than about 15% water, and pelletizing the polyethylene.

Abstract: An apparatus and method for filtering and classifying waste or process streams into three product streams using a polymeric net belt to drive a filter drum and hydrophobic polymeric filter element thereon. A matte of solids is doctored from the belt to provide a first product stream. A roller mounted on a fluid cylinder driven pivoted arm compresses the filter element to provide a smaller suspended solids stream for collection in a trough inside the drum. This second product stream is removed axially from the trough by means of a pump. A third clarified or effluent stream is produced and collected in the drum as the stream passes through the foam filter element. This third stream is removed axially in the direction opposite of said second stream. A shower keeps the foam in the compressed area water filled to prevent vapor lock or gas blockage in the cellular foam filter.

Abstract: Disclosed is a process for extraction of coniferous woods, such as pine, with supercritical fluids to recover tall oil and turpentine, or components thereof. Gases such as carbon dioxide, nitrous oxide, nitrogen, and lower alkanes or lower alkenes at temperatures above critical and pressures of about 100 psi above critical; i.e., supercritical fluids, are contacted with subdivided wood. The extracted wood is suitable for pulping and subsequent papermaking. The extract-bearing fluid is preferably stripped of the extracts by reducing the pressure in stages, each pressure reduction effecting removal of extracts of a narrowly-defined molecular weight range. The fluid is recompressed and recycled.

Abstract: The method of removing fine suspended solids from an effluent stream comprising passing said stream through at least two contiguous layers of an open-celled compressible hydrophobic polymeric material and compressing said layers to remove the solids loaded therein to regenerate said material, said material being layered so that the open cells of each layer are randomly oriented.

Abstract: The method of treating an activated sludge to facilitate dewatering thereof comprising the steps of acidifying the sludge to a pH below about 2.2, heating the acidified sludge to a temperature of from about 150.degree. to 210.degree. F. and maintaining the sludge at said temperature for a period of time sufficient to obtain a settling rate of solids in the first three minutes of at least two-sixteenths inch per minute.

Abstract: An improved method for removal of color bodies from aqueous effluents from paper and pulp mill manufacturing operations by ultrafiltration wherein the semi-permeable membrane utilized is a polyethyleneimine coated polysulfone film.

Abstract: An emission control system and a method of treating a gaseous effluent is disclosed. The system is particularly suited for treating gaseous effluents from a veneer dryer prior to venting to the atmosphere. The system comprises means for temperature adjustment, flow control, and catalytic oxidation of the effluent.