Abstract: A laundry charging system manages a laundry article and does laundry based on an article number. The article number is contained in a tag attached to the laundry article. The head office is connected to a plurality of sites via network. The system has an issuer in the head office to generate the article number, a database in the head office to store a laundry record that includes information related to the laundry article corresponding to the article number, an access identifying unit in the head office to evaluate a type of access to the head office from the site, and a charging unit in the head office. When the access identifying unit identifies an access to the head office from the site that requests to the issuer for issuing the article number, the charging unit charges the site that is an access source.

Abstract: A washing method comprising: suspending and washing laundry in a washing liquid that is supplied to a laundry tub; agitating and washing the laundry with a baffle in the washing liquid at a liquid level that is lower than a liquid level of the washing liquid that is supplied to the laundry tub during the suspending and washing of the laundry; and increasing or decreasing a liquid level of the washing liquid continuously between the suspending and washing of the laundry and the agitating and washing of the laundry while the laundry tub is spinning.

Abstract: A washing method comprising: suspending and washing laundry in a washing liquid that is supplied to a laundry tub; agitating and washing the laundry with a baffle in the washing liquid at a liquid level that is lower than a liquid level of the washing liquid that is supplied to the laundry tub during the suspending and washing of the laundry; and increasing or decreasing a liquid level of the washing liquid continuously between the suspending and washing of the laundry and the agitating and washing of the laundry while the laundry tub is spinning.

Abstract: It is intended to provide a process for producing unstable amorphous benzimidazole compounds having a proton pump inhibitor function, and stable solid preparations for medicinal use containing these compounds which are produced by blending such an amorphous benzimidazole compound with a nontoxic base such as a basic inorganic salt, forming an intermediate coating layer on the layer containing the active ingredient and further forming an enteric coating layer or a release-controlling coating layer.

Abstract: A washing apparatus includes a drive mechanism, a washing tub being configured to contain a washing article for washing and to be rotated by the drive mechanism, a casing that covers the washing tub, a liquid supply flow path for supplying the cleaning liquid for washing, a liquid discharge flow path, an air flow path, a detection portion being configured to detect whether or not the casing is filled with the cleaning liquid based on the cleaning liquid flowing into the air flow path, and a pump being configured to send the cleaning liquid to the liquid supply flow path, wherein the cleaning liquid is supplied to the casing in a condition that the casing communicates with the outside of the casing, after the washing article is put into the washing tub, and wherein the cleaning liquid is circulated, and wherein the washing tub is rotated, when the casing is filled.

Abstract: A sodium salt, magnesium salt, lithium salt, potassium salt, calcium salt or barium salt of (R)-2 -[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2 -pyridinyl]methyl]sulfinyl]-1H-benzimidazole, and a pharmaceutical composition comprising the salt. The novel salt is useful as an excellent antiulcer agent.

Abstract: It is intended to provide a process for producing unstable amorphous benzimidazole compounds having a proton pump inhibitor function, and stable solid preparations for medicinal use containing these compounds which are produced by blending such an amorphous benzimidazole compound with a nontoxic base such as a basic inorganic salt, forming an intermediate coating layer on the layer containing the active ingredient and further forming an enteric coating layer or a release-controlling coating layer.

Abstract: It is intended to provide a process for producing unstable amorphous benzimidazole compounds having a proton pump inhibitor function, and stable solid preparations for medicinal use containing these compounds which are produced by blending such an amorphous benzimidazole compound with a nontoxic base such as a basic inorganic salt, forming an intermediate coating layer on the layer containing the active ingredient and further forming an enteric coating layer or a release-controlling coating layer.

Abstract: It is intended to provide a process for producing unstable amorphous benzimidazole compounds having a proton pump inhibitor function, and stable solid preparations for medicinal use containing these compounds which are produced by blending such an amorphous benzimidazole compound with a nontoxic base such as a basic inorganic salt, forming an intermediate coating layer on the layer containing the active ingredient and further forming an enteric coating layer or a release-controlling coating layer.

Abstract: A sodium salt, magnesium salt, lithium salt, potassium salt, calcium salt or barium salt of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole, and a pharmaceutical composition comprising the salt. The novel salt is useful as an excellent antiulcer agent.

Abstract: Provided is a crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole showing an X-ray powder diffraction pattern having characteristic peaks at interplanar spacings (d) of 10.06±0.2, 8.70±0.2, 6.57±0.2, 5.59±0.2 and 4.00±0.2 Angstroms. The present invention provides a stable antiulcer drug superior in the absorbability.

Abstract: The present invention relates to a production method of a crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole.n?H2O (wherein n? is about 0 to about 0.1) or a salt thereof, which characteristically includes crystallization from an organic solvent solution or suspension in which (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole.nH2O (wherein n is about 0.1 to about 1.0) or a salt thereof has been dissolved or suspended, and the like, and provides a convenient method for efficiently producing an optically active sulfoxide derivative having an extremely high enantiomer excess in high yield at an industrial large scale.

Abstract: A washing apparatus is provided with a washing tub 2 whose rotating axis is in a horizontal direction or in a horizontally inclined direction, and has a concave and convex curve surface 22 installed on an inside wall surface of the washing tub 2 as well as has a baffle 25 protruding in the direction of the rotating axis installed. Then, by rotating the washing tub with a level of a cleaning liquid to be supplied to the washing tub 2 set to be higher than the rotating axis, a spurious non-gravity wash method is adopted in which damage to a washing article is small. In addition, by rotating the washing tub 2 with the level of the cleaning liquid to be supplied to the washing tub 2 set to be lower than the rotating axis, a beat wash method in which water saving effect is high is adopted.

Abstract: The washing apparatus has a frame body to be filled with a cleaning liquid. The frame body is rotated within a casing by a drive motor. The frame body has an inner periphery having a wavy patterned surface. An inner diameter D of the frame body is set to more than or equal to 600 mm and less than or equal to 850 mm. The frame body is rotated so that a peripheral speed of the inner periphery is more than or equal to 28 m/min and less than or equal to 57 m/min. A height h of the wave form is set to more than or equal to 2.0% and less than or equal to 9.0% of the inner diameter D, and a pitch p of the wave form is set to more than or equal to 2.0% and less than or equal to 9.0% of a peripheral length L of an imaginary circle having a diameter of the inner diameter D.

Abstract: The present invention relates to a production method of a crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole.n?H2O (wherein n? is about 0 to about 0.1) or a salt thereof, which characteristically includes crystallization from an organic solvent solution or suspension in which (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole.nH2O (wherein n is about 0.1 to about 1.0) or a salt thereof has been dissolved or suspended, and the like, and provides a convenient method for efficiently producing an optically active sulfoxide derivative having an extremely high enantiomer excess in high yield at an industrial large scale.

Abstract: The present invention relates to a production method of a crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole.n?H2O (wherein n? is about 0 to about 0.1) or a salt thereof, which characteristically includes crystallization from an organic solvent solution or suspension in which (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-benzimidazole.nH2O (wherein n is about 0.1 to about 1.0) or a salt thereof has been dissolved or suspended, and the like, and provides a convenient method for efficiently producing an optically active sulfoxide derivative having an extremely high enantiomer excess in high yield at an industrial large scale.

Abstract: A washing apparatus includes a drive mechanism, a washing tub being configured to contain a washing article for washing and to be rotated by the drive mechanism, a casing that covers the washing tub, a liquid supply flow path for supplying the cleaning liquid for washing, a liquid discharge flow path, an air flow path, a detection portion being configured to detect whether or not the casing is filled with the cleaning liquid based on the cleaning liquid flowing into the air flow path, and a pump being configured to send the cleaning liquid to the liquid supply flow path, wherein the cleaning liquid is supplied to the casing in a condition that the casing communicates with the outside of the casing, after the washing article is put into the washing tub, and wherein the cleaning liquid is circulated, and wherein the washing tub is rotated, when the casing is filled.

Abstract: Provided is a crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole showing an X-ray powder diffraction pattern having characteristic peaks at interplanar spacings (d) of 10.06±0.2, 8.70±0.2, 6.57±0.2, 5.59±0.2 and 4.00±0.2 Angstroms. The present invention provides a stable antiulcer drug superior in the absorbability.

Abstract: The washing apparatus has a frame body to be filled with a cleaning liquid. The frame body is rotated within a casing by a drive motor. The frame body has an inner periphery having a wavy patterned surface. An inner diameter D of the frame body is set to more than or equal to 600 mm and less than or equal to 850 mm. The frame body is rotated so that a peripheral speed of the inner periphery is more than or equal to 28 m/min and less than or equal to 57 m/min. A height h of the wave form is set to more than or equal to 2.0% and less than or equal to 9.0% of the inner diameter D, and a pitch p of the wave form is set to more than or equal to 2.0% and less than or equal to 9.0% of a peripheral length L of an imaginary circle having a diameter of the inner diameter D.

Abstract: It is intended to provide a process for producing unstable amorphous benzimidazole compounds having a proton pump inhibitor function, and stable solid preparations for medicinal use containing these compounds which are produced by blending such an amorphous benzimidazole compound with a nontoxic base such as a basic inorganic salt, forming an intermediate coating layer on the layer containing the active ingredient and further forming an enteric coating layer or a release-controlling coating layer.