Abstract: An object of the present invention is to provide a piezoelectric stack substantially free from deterioration in performance and having high reliability, and a production method thereof.

Abstract: A pyrazolopyrimidine derivative represented by formula (1) and pharmaceutically acceptable salt thereof exhibit excellent inhibitory activity against MAPKAP-K2. Accordingly, medicines containing this compound as an active ingredient are expected to be effective for treating diseases mediated by MAPKAP-K2 such as, for example, inflammatory disorder, autoimmune diseases, destructive osteopathy, cancer and/or tumor growth.

Abstract: A pyrazolopyrimidine derivative represented by formula (1) and pharmaceutically acceptable salt thereof exhibit excellent inhibitory activity against MAPKAP-K2. Accordingly, medicines containing this compound as an active ingredient are expected to be effective for treating diseases mediated by MAPKAP-K2 such as, for example, inflammatory disorder, autoimmune diseases, destructive osteopathy, cancer and/or tumor growth.

Abstract: A harness protecting structure is provided for a vehicular horn for a vehicle, in which the vehicle has a grille defining an air intake opening in a front part of the vehicle, a radiator located posterior to the grille, and the horn being disposed in front of the radiator and facing the opening of the grille. The grille is provided with a peripheral wall, the peripheral wall extending posterior to the lower and side edge of the grill, and a part of the peripheral wall extending across and anterior to a peripheral region of the horn so as to form a protective surface. The harness of the horn is laid from the outside of the region of the horn behind the protective surface.

Abstract: A pyrazolo[1,5-a]pyridine derivative represented by formula (I) and salt thereof exhibit excellent MAPKAP-K2 inhibitory activity. Accordingly, medicines comprising this compound as an active ingredient are expected to be valuable for treating or preventing diseases mediated by MAPKAP-K2 such as inflammatory injury, autoimmune diseases, asteropathia destruens, cancer and/or growth of tumor.

Abstract: In a refrigerating cycle incorporating a second flow controller having a throttle section, which is composed of an inlet noise eliminating space, an inlet side porous permeable member communicating in a refrigerant flow direction, an orifice, an outlet side foamed metal, and an outlet noise eliminating space, and a multi-directional valve, a gas/liquid two-phase refrigerant is caused to pass through the throttle section.

Abstract: A pyrazolopyrimidine derivative represented by formula (1) and pharmaceutically acceptable salt thereof exhibit excellent inhibitory activity against MAPKAP-K2. Accordingly, medicines containing this compound as an active ingredient are expected to be effective for treating diseases mediated by MAPKAP-K2 such as, for example, inflammatory disorder, autoimmune diseases, destructive osteopathy, cancer and/or tumor growth.

Abstract: In a refrigerating cycle incorporating a second flow controller having a throttle section, which is composed of an inlet noise eliminating space 19, an inlet side porous permeable member 20 communicating in a refrigerant flow direction, an orifice 23, an outlet side foamed metal 25, and an outlet noise eliminating space 27, and a multi-directional valve, a gas/liquid two-phase refrigerant is caused to pass through the throttle section.

Abstract: A pyrazolo[1,5-a]pyridine derivative represented by formula (I) and salt thereof exhibit excellent MAPKAP-K2 inhibitory activity. Accordingly, medicines comprising this compound as an active ingredient are expected to be valuable for treating or preventing diseases mediated by MAPKAP-K2 such as inflammatory injury, autoimmune diseases, asteropathia destruens, cancer and/or growth of tumor.

Abstract: An object is to provide a wheel action force detection system and a wheel action force detection method for finding braking force of a vehicle having a disc brake at the time of braking with high accuracy.

Abstract: The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent kinase inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for a protein kinase mediated disorder in which kinase is implicated, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.

Abstract: The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent MAPKAP-K2 inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for MAPKAP-K2 mediated disorder, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.

Abstract: A physical sensor having a pressure sensing layer having such property that electrical resistance is changed by application of a stress, and electrical insulating layers which are integrally formed on opposite two surfaces of the pressure sensing layer, respectively, wherein the pressure sensing layer has a matrix comprising glass, and an electrically conductive particle having electrical conductivity and dispersed in the matrix and preferably, the electrically conductive particle includes RuO2, and a thickness of the pressure sensing layer is 1 ?m to 200 ?m, and it is preferable that one pair of electrodes are disposed on the pressure sensing layer.

Abstract: A noble metallic firing tip includes a protruding portion which is formed partly on its outer circumferential surface so as to protrude in the direction substantially normal to the axis of a center electrode. The protruding portion is disposed in confronting relationship via a discharge gap with a distal end of an opposed portion of a ground electrode far from its leg portion.

Abstract: A dynamic quantity sensor device capable of measuring a dynamic quantity at a high precision and securing insulation of a pressure sensing body easily. This dynamic quantity sensor includes a pressure sensing body composed of composite ceramics in which a material having a pressure resistance effect is dispersed on a matrix made of an electrical insulation ceramic material and a pressure receiving body having an electrical insulation characteristic and disposed on a pressure receiving surface of the pressure receiving body, wherein the pressure sensing body and the pressure receiving body are integrated with each other.

Abstract: An object of the present invention is to provide a piezoelectric stack substantially free from deterioration in performance and having high reliability, and a production method thereof.

Abstract: A physical sensor having a pressure sensing layer having such property that electrical resistance is changed by application of a stress, and electrical insulating layers which are integrally formed on opposite two surfaces of the pressure sensing layer, respectively. The pressure sensing layer comprises a matrix comprising glass, and an electrically conductive particle having electrical conductivity and dispersed in the matrix. Preferably, the electrically conductive particle comprises RuO2, and a thickness of the pressure sensing layer is 1 ?m to 200 ?m. It is preferable that one pair of electrodes are disposed on the pressure sensing layer.

Abstract: In a refrigerating cycle incorporating a second flow controller having a throttle section, which is composed of an inlet noise eliminating space 19, an inlet side porous permeable member 20 communicating in a refrigerant flow direction, an orifice 23, an outlet side foamed metal 25, and an outlet noise eliminating space 27, and a multi-directional valve, a gas/liquid two-phase refrigerant is caused to pass through the throttle section.

Abstract: An object of this invention is to provide a dynamic quantity sensor device capable of measuring a dynamic quantity at a high precision and securing insulation of a pressure sensing body easily. This dynamic quantity sensor comprises a pressure sensing body 11 composed of composite ceramics in which material having pressure resistance effect is dispersed on a matrix made of electrical insulation ceramic material and a pressure receiving body 12 having electrical insulation characteristic and disposed on a pressure receiving surface of the pressure receiving body 11, wherein the pressure sensing body and the pressure receiving body are integrated with each other.

Abstract: A noble metallic firing tip includes a protruding portion which is formed partly on its outer circumferential surface so as to protrude in the direction substantially normal to the axis of a center electrode. The protruding portion is disposed in confronting relationship via a discharge gap with a distal end of an opposed portion of a ground electrode far from its leg portion.