Patents by Inventor Hiroki Yoshioka

Hiroki Yoshioka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12220426
    Abstract: An object is to provide a Th1-increasing agent that can reduce constraints on storage conditions and feeding form and sufficiently increase Th1 at lower doses. A Th1-increasing agent containing a cellulose derivative as an active ingredient, the cellulose derivative having a degree of butyryl substitution of 0.3 or greater and 2.6 or less, and a total degree of substitution of 0.5 or greater and 2.8 or less.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: February 11, 2025
    Assignee: DAICEL CORPORATION
    Inventors: Hiroshi Ohno, Tadashi Takeuchi, Shu Shimamoto, Shuuji Yoshioka, Eiji Miyauchi, Hiroki Negishi
  • Patent number: 12223541
    Abstract: A virtual try-on system includes one or more hardware processors configured to function as a learning unit, an acquisition unit, a deriving unit, and a generation unit. The learning unit learns, by machine learning using three-dimensional data of a try-on person, a learning model using a teacher try-on person image as input data, and using a body shape parameter indicating a body shape of the try-on person represented by the teacher try-on person image and compositing position information of a clothing image in the teacher try-on person image as output data. The acquisition unit acquires a try-on person image. The deriving unit derives output data of the try-on person represented by the try-on person image using the try-on person image and the learning model. The generation unit generates a virtual try-on image by compositing the try-on person image and the clothing image using the derived output data.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: February 11, 2025
    Assignees: Kabushiki Kaisha Toshiba, Toshiba Digital Solutions Corporation
    Inventors: Hiroki Ueda, Hisao Yoshioka
  • Patent number: 12219533
    Abstract: A user terminal, when using a high frequency band having a frequency higher than a certain frequency band including one or a plurality of frequency ranges, increases number of symbols constituting one slot. The user terminal transmits and receives signals by using the slot with the increased number of symbols.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: February 4, 2025
    Assignee: NTT DOCOMO, INC.
    Inventors: Hiroki Harada, Shohei Yoshioka, Satoshi Nagata
  • Publication number: 20250032626
    Abstract: The present invention provides four-branched water-soluble polymers for medical use that are represented by the following formula (1) or the formula (2) (the symbols in the following formulas are as defined in the specification.
    Type: Application
    Filed: November 21, 2022
    Publication date: January 30, 2025
    Applicant: NOF CORPORATION
    Inventors: Ken HAMURA, Hiroki YOSHIOKA, Masaki KAMIYA
  • Patent number: 12187846
    Abstract: The invention provides a high-molecular-weight polyethylene glycol derivative that does not cause vacuolation of cells. The degradable polyethylene glycol derivative is represented by the following formula (1): wherein m is 1-7, n1 and n2 are each independently 45-682, p is 1-4, R is an alkyl group having 1-4 carbon atoms, Z is an oligopeptide with 2-8 residues composed of neutral amino acids excluding cysteine, Q is a residue of a compound having 2-5 active hydrogens, X is a functional group capable of reacting with a bio-related substance, and L1, L2, L3, L4 and L5 are each independently a single bond or a divalent spacer.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: January 7, 2025
    Assignees: NOF Corporation, Tokyo Institute of Technology
    Inventors: Hiroki Yoshioka, Masaki Kamiya, Yuji Yamamoto, Midori Hirai, Akiko Sasaki, Nobuhiro Nishiyama, Makoto Matsui, Hiroyasu Takemoto, Kazuki Miyauchi, Takahiro Nomoto, Keishiro Tomoda
  • Publication number: 20240408230
    Abstract: The present invention provides a lipid nanoparticle used for delivering a nucleic acid to a brain tissue, including an ionic lipid represented by the formula (1), phospholipid, cholesterol, and a dimyristoylglycerol PEG with a number average molecular weight of PEG chain of 4,000 to 6,000, wherein an amount of the dimyristoylglycerol PEG is 1 to 6 mol % with respect to the total of the ionic lipid represented by the formula (1), the phospholipid, and the cholesterol (the symbols in the formula (1) are as defined in the specification).
    Type: Application
    Filed: September 26, 2022
    Publication date: December 12, 2024
    Applicants: NOF CORPORATION, NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY
    Inventors: Kota TANGE, Hiroki YOSHIOKA, Yuta NAKAI, Hidetaka AKITA, Yu SAKURAI, Hiroki TANAKA, Shoya FUJITA
  • Publication number: 20240385153
    Abstract: The present invention provides an analysis method including separating a compound of the formula (1): contained in a polyoxyethylene derivative by reversed-phase chromatography, and detecting the compound with an ultraviolet visible spectrometer detector, in which ultraviolet light with a wavelength shorter than 200 nm as the detection wavelength is used, and an acidic substance with a maximum molar absorption coefficient of not more than 20 M?1cm?1 at 190 to 200 nm and a pKa of not more than 4 is used as an additive to the mobile phase for analysis.
    Type: Application
    Filed: June 30, 2022
    Publication date: November 21, 2024
    Applicant: NOF CORPORATION
    Inventors: Masaki KAMIYA, Akira SUZUKI, Hiroki YOSHIOKA
  • Patent number: 12149225
    Abstract: Among a plurality of electrodes for mounting purpose, all of the electrodes for mounting purpose but two paired ones of the electrodes for mounting purpose that are connected to driving electrodes each have a wiring pattern for use in electrical connection between terminals for external connection and mounting terminals of IC. These wiring patterns each have a constricted portion smaller in width than the other portions that prevents the conduction of heat.
    Type: Grant
    Filed: February 12, 2020
    Date of Patent: November 19, 2024
    Assignee: DAISHINKU CORPORATION
    Inventor: Hiroki Yoshioka
  • Publication number: 20240366508
    Abstract: The invention provides a cationic lipid, a lipid membrane structure containing same, and use thereof. The cationic lipid is represented by the formula (1) wherein R1a, R1b, R2a, R2b, R3a, R3b, Xa, Xb, Ya, Yb, Za, and Zb are as defined in the specification.
    Type: Application
    Filed: July 15, 2024
    Publication date: November 7, 2024
    Applicants: NOF CORPORATION, NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY
    Inventors: Yuta NAKAI, Kota TANGE, Hiroki YOSHIOKA, Shinya TAMAGAWA, Hidetaka AKITA, Hiroki TANAKA, Nae TAKATA, Manami KONISHI, Tatsunari TAKAHASHI
  • Publication number: 20240357389
    Abstract: A user data rate estimation device acquires a reception power in a user, and receives input of information regarding a communication environment of the user. Next, the device calculates a wireless resource to be allocated to the user on the basis of information regarding a bandwidth, a scheduling method, and the number of users included in the information regarding the communication environment, calculates an overhead on the basis of information regarding a communication standard, a frequency band, and a bandwidth included in the information regarding the communication environment, and determines a communication mode on the basis of the reception power or communication quality information converted from the reception power. Then, the device calculates a user data rate on the basis of the wireless resource, the overhead, the communication mode, and information regarding the number of spatial streams included in the information regarding the communication environment.
    Type: Application
    Filed: August 27, 2021
    Publication date: October 24, 2024
    Applicant: NIPPON TELEGRAPH AND TELEPHONE CORPORATION
    Inventors: Masashi IWABUCHI, Tomoaki OGAWA, Hiroki YOSHIOKA, Masayoshi NABESHIMA, Yasushi TAKATORI
  • Patent number: 12064513
    Abstract: The invention provides a cationic lipid, a lipid membrane structure containing same, and use thereof. The cationic lipid is represented by the formula (1) wherein R1a, R1b, R2a, R2b, R3a, R3b, Xa, Xb, Ya, Yb, Za, and Zb are as defined in the specification.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: August 20, 2024
    Assignees: NOF CORPORATION, NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY
    Inventors: Yuta Nakai, Kota Tange, Hiroki Yoshioka, Shinya Tamagawa, Hidetaka Akita, Hiroki Tanaka, Nae Takata, Manami Konishi, Tatsunari Takahashi
  • Patent number: 12028042
    Abstract: In a piezoelectric resonator device according to one or more embodiments, an internal space for hermetically sealing a vibrating part including a first excitation electrode and a second excitation electrode of a crystal resonator plate is formed by bonding a first sealing member and a second sealing member respectively to the crystal resonator plate. A through hole is formed in the second sealing member. A through electrode is formed along an inner wall surface of the through hole to establish conduction between an electrode formed on a first main surface and an external electrode terminal formed on a second main surface. A corrosion resistance structure to solder is formed on the through electrode that establishes conduction between the electrode and the external electrode terminal with a conductive metal other than Au.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: July 2, 2024
    Assignee: DAISHINKU CORPORATION
    Inventors: Satoru Ishino, Hiroki Yoshioka, Hiroki Fujiwara
  • Patent number: 11933520
    Abstract: A fluid-heating device for heating fluid with a heater includes: a heating portion that is molded so as to cover the surrounding of the heater; and a support body integrally cast into the heating portion, the heating portion being molded in a state in which the heater is supported by the support body in a die for molding the heating portion.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: March 19, 2024
    Assignee: MARELLI CABIN COMFORT JAPAN CORPORATION
    Inventors: Takeshi Ogasawara, Naohisa Kamiyama, Hiroki Yoshioka, Takashi Otsuka, Daiju Suzuki
  • Patent number: 11905366
    Abstract: A method for producing a multi-arm type polyethylene glycol derivative, which includes carrying out the following in order: Step (A): protecting an even number of hydroxyl groups, while leaving only the hydroxyl group at the 1-position of a polyhydric alcohol having an odd number of hydroxyl groups, other than the hydroxyl group at the 1-position by cyclic benzylidene acetalization, Step (B): linking two molecules of the compound obtained in step (A) to a compound for introducing a specific linker by etherification reaction, Step (C): deprotecting the cyclic benzylidene acetal structure at the terminal of the compound obtained in step (B), Step (D): polymerizing 3 to 600 mol of ethylene oxide to each hydroxyl group of the compound obtained in step (C) to obtain a multi-arm type polyethylene glycol derivative, and Step (E): functionalizing the hydroxyl group at the terminal of the multi-arm type polyethylene glycol derivative obtained in step (D).
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: February 20, 2024
    Assignee: NOF CORPORATION
    Inventors: Akihide Onozawa, Hiroki Yoshioka, Masaki Kamiya
  • Patent number: 11905367
    Abstract: A branched monodispersed polyethylene glycol represented by the formula (1): wherein X1 is a functional group that forms a covalent bond upon a reaction with a functional group present in a biofunctional molecule; n is an integer of 4 to 50, which represents number of repeating units of ethylene oxide units; and L1 represents a single bond, —NH—, -L2-(CH2)m1- or -L2-(CH2)m1-L3-(CH2)m2-, L2 represents an ether bond, an amide bond, an urethane bond or a single bond, L3 represents an ether bond, an amide bond or an urethane bond, and m1 and m2 represent each independently an integer of 1 to 5.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: February 20, 2024
    Assignee: NOF CORPORATION
    Inventors: Mika Hamura, Yuki Matsuno, Hiroki Yoshioka
  • Publication number: 20220389629
    Abstract: To provide a flexible conductive base member and a multilayer conductive base member including the same, having no problem of failing to function as a contact and causing a variation in height between contacts. There are a covered region 10 covered with a noble metal and a non-covered region 20 not circumferentially covered with a noble metal on a surface of a reticulated fibrous body 50. The covered region 10 is located at an intersection 7 of fibers 5 of the reticulated fibrous body 50, and the intersections 7 are connected to each other. The non-covered region 20 is located between the intersections 7 of the fibers 5 of the reticulated fibrous body 50.
    Type: Application
    Filed: November 27, 2020
    Publication date: December 8, 2022
    Applicant: UNITED PRECISION TECHNOLOGIES CO., LTD.
    Inventors: SATOSHI OSAWA, HIDEKI SATO, SHUJI KUNIOKA, HIROKI YOSHIOKA
  • Publication number: 20220387609
    Abstract: A bio-related substance bonded to a branched and degradable polyethylene glycol derivative that is degraded in the cells represented by the following formula (A): wherein each symbol is as defined in the present specification, is provided by the present invention.
    Type: Application
    Filed: March 26, 2020
    Publication date: December 8, 2022
    Applicants: NOF CORPORATION, TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Hiroki YOSHIOKA, Kazuki OSAKAMA, Mika HAMURA, Takanori INABA, Nobuhiro NISHIYAMA, Makoto MATSUI, Hiroyasu TAKEMOTO, Takahiro NOMOTO, Xiaohang SUN
  • Publication number: 20220380533
    Abstract: A multi-arm, degradable polyethylene glycol derivative with a high molecular weight that does not cause vacuolation of cells is provided. A degradable polyethylene glycol derivative represented by the following formula (1): wherein n1 and n2 are each independently 45-950, W1 and W2 are each independently an oligopeptide of 2-47 residues, a1 and a2 are each independently 1-8, Q is a hydrocarbon chain having 2-12 carbon atoms and optionally containing an oxygen atom and/or a nitrogen atom, X1 and X2 are each independently a functional group capable of reacting with a bio-related substance, and L1, L2, L3, L4, L5 and L6 are each independently a divalent spacer.
    Type: Application
    Filed: September 25, 2020
    Publication date: December 1, 2022
    Inventors: Hiroki Yoshioka, Ken Hamura, Kazuki Osakama, Nobuhiro Nishiyama
  • Publication number: 20220362397
    Abstract: A heterobifunctional monodisperse polyethylene glycol with two adjacent monodisperse polyethylene glycol side chains, in which a peptide linker is degraded by intracellular enzymes to release a drug slowly and effectively mask the hydrophobicity of the drug, and an antibody-drug conjugate in which the antibody and the drug are bound using same is provided. A heterobifunctional monodisperse polyethylene glycol represented by the formula (1): wherein each symbol in the formula (1) is as defined in the DESCRIPTION.
    Type: Application
    Filed: September 25, 2020
    Publication date: November 17, 2022
    Applicant: NOF CORPORATION
    Inventors: Yuki MATSUNO, Hiroki YOSHIOKA, Akira SUZUKI
  • Publication number: 20220339290
    Abstract: A branched degradable polyethylene glycol derivative with a high molecular weight that does not cause vacuolation of cells is provided. A branched degradable polyethylene glycol derivative represented by the following formula (1), containing, in a molecule, an oligopeptide that is degraded in the cells: wherein k1 and k2 are each independently 1-12, j1 and j2 are each independently 45-950, R is a hydrogen atom, a substituted or unsubstituted alkyl group having 1-12 carbon atoms, a substituted aryl group, an aralkyl group or a heteroalkyl group, Z is an oligopeptide that is degraded by enzyme in the cells, X is a functional group capable of reacting with a bio-related substance, and L1 and L2 are each independently a single bond or a divalent spacer.
    Type: Application
    Filed: September 25, 2020
    Publication date: October 27, 2022
    Inventors: Ken Hamura, Hiroki Yoshioka, Kazuki Osakama, Nobuhiro Nishiyama