Patents by Inventor Hironori Kobayashi
Hironori Kobayashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250020655Abstract: A method for analyzing leucine and isoleucine for newborn mass-screening or similar tests by multiple reaction monitoring (MRM) measurements using a tandem mass spectrometer is provided. The method includes: a measurement step for acquiring intensity information of ions originating from leucine and isoleucine by performing, on a specimen, a first MRM measurement for at least one MRM transition selected from a group of m/z 132>69, m/z 132>57, m/z 132>56, m/z 132>43, m/z 132>41, m/z 132>39, m/z 132>30 and m/z 132>27 as well as a second MRM measurement for an MRM transition of m/z 132>86; and a processing step for discriminating whether the specimen contains leucine or isoleucine, or for determining a relative abundance of leucine and isoleucine in the specimen, based on a qualifier ion ratio which is a ratio between a signal intensity obtained by the first MRM measurement and a signal intensity obtained by the second MRM measurement.Type: ApplicationFiled: July 1, 2024Publication date: January 16, 2025Applicants: SHIMADZU CORPORATION, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITYInventors: Takanari HATTORI, Jun WATANABE, Hironori KOBAYASHI, Yoshitomo NOTSU
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Patent number: 12196743Abstract: Provided is a method by which the disaccharides derived from glycosaminoglycans can be analyzed in a stable and highly reproducible manner. A method for analyzing a glycosaminoglycan according to the present invention includes: a first process for producing a plurality of kinds of disaccharides derived from a glycosaminoglycan in a biological sample by adding a plurality of kinds of glycosaminoglycan-specific enzymes to the biological sample; and a second process for separating and analyzing the plurality of kinds of disaccharides by a liquid chromatography-mass spectrometry method, where a column used for liquid chromatography in the liquid chromatography-mass spectrometry method is a column packed with a stationary-phase support to which an amide group as a functional group is bound, or a column packed with a stationary-phase support to which an adamantyl group as a functional group is bound.Type: GrantFiled: October 14, 2021Date of Patent: January 14, 2025Assignees: SHIMADZU CORPORATION, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITYInventors: Takanari Hattori, Jun Watanabe, Tetsuo Iida, Misa Tanaka, Hironori Kobayashi, Shunji Tomatsu
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Publication number: 20250003930Abstract: First and second MRM transitions for a target substance, a first reference value concerning a measured intensity of the first MRM transition, and a second reference value concerning the measured-intensity ratio between the first and second MRM transitions are set. MRM measurements of an analyte sample using the first and second MRM transitions are performed to obtain a first intensity of the first MRM transition and a second intensity of the second MRM transition (Steps 11 and 12). The value of the first intensity is compared with the first reference value to determine whether the target substance is possibly contained (first determination; Step 14). For a target substance considered to be possibly contained in the analyte sample, the ratio between the first and second intensities is compared with the second reference value to determine whether the target substance is contained (second determination; Step 18).Type: ApplicationFiled: June 25, 2024Publication date: January 2, 2025Applicants: SHIMADZU CORPORATION, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITYInventors: Takanari HATTORI, Jun WATANABE, Kengo MAEDA, Hironori KOBAYASHI, Yoshitomo NOTSU
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Publication number: 20240344267Abstract: Synthetic resin leather includes a base material, and a skin layer that is stacked on the base material and is made of a synthetic resin capable of being elastically deformed. Multiple micro recess parts are intermittently and regularly formed on a surface of the skin layer. The multiple micro recess parts form multiple bottom face parts that are located at a substantially constant depth from the surface of the skin layer, and multiple inner side face parts that extend from the surface of the skin layer to the multiple bottom face parts and are capable of being elastically deformed.Type: ApplicationFiled: April 9, 2024Publication date: October 17, 2024Applicants: OKAMOTO INDUSTRIES, INC., HONDA MOTOR CO., LTD.Inventors: Hironori KOBAYASHI, Naoto MATSUMOTO, Shin NAKAYA, Yoritaka ASADA, Tomoyuki UEMURA
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Publication number: 20240233659Abstract: A display device includes a display panel and a backlight device. A display system includes: a display driver; a light source driver that drives the backlight device, based on luminance information that sets a luminance of a plurality of light source elements; and a display controller. The light source driver causes the plurality of light source elements to emit light, based on a light-emission frame update that is faster than an image frame update. The light source driver causes the plurality of light source elements to emit light in an i-th light-emission frame. At this point, the luminance information of the light source element corresponding to a scan area scanned by the display driver in the i-th light-emission frame, of the plurality of light source elements, is updated, based on image data in the scan area at a timing before the i-th light-emission frame.Type: ApplicationFiled: October 18, 2023Publication date: July 11, 2024Inventors: Yota SASAKI, Hironori KOBAYASHI
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Publication number: 20240135890Abstract: A display device includes a display panel and a backlight device. A display system includes: a display driver; a light source driver that drives the backlight device, based on luminance information that sets a luminance of a plurality of light source elements; and a display controller. The light source driver causes the plurality of light source elements to emit light, based on a light-emission frame update that is faster than an image frame update. The light source driver causes the plurality of light source elements to emit light in an i-th light-emission frame. At this point, the luminance information of the light source element corresponding to a scan area scanned by the display driver in the i-th light-emission frame, of the plurality of light source elements, is updated, based on image data in the scan area at a timing before the i-th light-emission frame.Type: ApplicationFiled: October 17, 2023Publication date: April 25, 2024Inventors: Yota SASAKI, Hironori KOBAYASHI
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Patent number: 11927516Abstract: A sample scraping method and a sample scraping device capable of efficiently scraping and collecting a biological tissue section without waste while suppressing contamination is provided. In a sample scraping method for scraping and collecting a biological tissue section held on a slide, the FFPE section held on the slide is heated, and the heated FFPE section is scraped by a blade such that the FFPE section that has been scraped off and remains on the blade is collected in a container.Type: GrantFiled: February 15, 2022Date of Patent: March 12, 2024Assignee: SYSMEX CORPORATIONInventors: Soichi Oue, Yutaka Maeda, Junyi Ding, Takayuki Koshihara, Hironori Kobayashi, Yasuhiro Kouchi
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Patent number: 11857310Abstract: A physiological parameter processing apparatus includes an input interface section that acquires respiration data produced based on a respiratory gas that is obtained from at least one of a mouth and nose of a subject, and an analyzing section that analyzes in real time the respiration data acquired through the input interface section, and that produces analysis result data which can be displayed in real time.Type: GrantFiled: May 30, 2018Date of Patent: January 2, 2024Assignee: NIHON KOHDEN CORPORATIONInventors: Hironori Kobayashi, Yukio Nonaka, Kazuri Higashi, Takayuki Sugiyama
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Publication number: 20230411684Abstract: Provided are: an ion-conductive solid which can be produced by heat treatment at a low temperature and which has high ion conductivity; and, an all-solid-state battery having the ion-conductive solid. An ion-conductive solid containing an oxide represented by the general formula Li6-3a-2b-c-dYi1-c-dAlaMgbZrcCedB3O9; and, an all-solid-state battery having at least a positive electrode, a negative electrode, and an electrolyte, at least one element selected from the group consisting of the positive electrode, the negative electrode, and the electrolyte containing the ion-conductive solid (In the formula, a is such that 0.000?a?0.800, b is such that 0.000?b?0.800, c is such that 0.000?c?0.400, d is such that 0.000?d?0.400, and a and b are real numbers satisfying 0.005?a+b?0.800.).Type: ApplicationFiled: September 5, 2023Publication date: December 21, 2023Inventors: Saori HASHIMOTO, Yoshitaka SHIBA, Noriko SAKAMOTO, Takeshi KOBAYASHI, Toyoki OKUMURA, Hironori KOBAYASHI, Tomonari TAKEUCHI
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Publication number: 20230324349Abstract: One mode of a method for analyzing acylcarnitine according to the present invention is a method for analyzing C5 acylcarnitine using a tandem mass spectrometer, the method including: a measurement step of performing MRM measurement on a specimen according to at least one of MRM transitions of m/z 24>187, m/z 246>57, m/z 246>41, and m/z 246>29; and a processing step of distinguishing between isovalerylcarnitine and pivaloylcarnitine which is an isomer of isovalervicarnitine in the specimen or determining whether or not C5 acylcarnitine in the specimen includes pivaloylcarnitine, using a measurement result obtained in the measurement step. This makes it possible to satisfactorily distinguish between isovalerylcarnitine and pivaloylcarnitine, which have been conventionally difficult to distinguish.Type: ApplicationFiled: August 24, 2021Publication date: October 12, 2023Applicants: Shimadzu Corporation, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITYInventors: Takanari HATTORI, Jun WATANABE, Misa TANAKA, Hironori KOBAYASHI, Yoshitomo NOTSU
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Publication number: 20230204614Abstract: In a dispensing system, a body is arranged outside a specimen processing cabinet, and in a state where a hand and a dispenser are inserted into the specimen processing cabinets, a specimen accommodated in a specimen container held by the hand is dispensed into a dispensing container by the dispenser.Type: ApplicationFiled: May 27, 2021Publication date: June 29, 2023Applicants: KAWASAKI JUKOGYO KABUSHIKI KAISHA, SYSMEX CORPORATIONInventors: Noboru TAKAGI, Atsushi KAMEYAMA, Eiji YOSHIKUWA, Toshiyuki TSUJIMORI, Shogo KUBOTA, Satoshi OUCHI, Yukio IWASAKI, Yasuhiro KOUCHI, Soichi OUE, Hironori KOBAYASHI, Yutaka MAEDA, Takayuki KOSHIHARA
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Publication number: 20230122509Abstract: Provided is a method by which the disaccharides derived from glycosaminoglycans can be analyzed in a stable and highly reproduceable manner. A method for analyzing a glycosaminoglycan according to the present invention includes: a first process for producing a plurality of kinds of disaccharides derived from a glycosaminoglycan in a biological sample by adding a plurality of kinds of glycosaminoglycan-specific enzymes to the biological sample: and a second process for separating and analyzing the plurality of kinds of disaccharides by a liquid chromatography-mass spectrometry method, where a column used for liquid chromatography in the liquid chromatography-mass spectrometry method is a column packed with a stationary-phase support to which an amide group as a functional group is bound, or a column packed with a stationary-phase support to which an adamantyl group as a functional group is bound.Type: ApplicationFiled: October 14, 2021Publication date: April 20, 2023Applicants: SHIMADZU CORPORATION, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITYInventors: Takanari HATTORI, Jun WATANABE, Tetsuo IIDA, Misa TANAKA, Hironori KOBAYASHI, Shunji TOMATSU
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Patent number: 11536994Abstract: A liquid crystal device includes a liquid crystal panel and a liquid crystal driver. The liquid crystal panel includes a segment electrode, a segment signal line connected to the segment electrode, and a segment signal line connected to the segment electrode. The liquid crystal driver includes a segment terminal to be connected to the segment signal line, a segment driving circuit that outputs a segment driving signal to the segment terminal, a segment terminal to be connected to the segment signal line, and an anomalous segment detection circuit that detects anomalous driving of the segment electrode based on a segment monitoring signal that is input to the segment terminal from the segment electrode via the segment signal line.Type: GrantFiled: August 19, 2021Date of Patent: December 27, 2022Assignee: SEIKO EPSON CORPORATIONInventors: Hironori Kobayashi, Norichika Muraki
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Publication number: 20220356557Abstract: Provided is an Fe—Pt—BN-based sputtering target that has a high relative density and that suppresses particle generation. The Fe—Pt—BN-based sputtering target has, as a residue after dissolution in aqua regia measured by a procedure below, the particle size distribution in which D90 is 5.5 ?m or less and a proportion of fine particles smaller than 1 ?m is 35% or less. The procedure includes: (1) cutting out an about 4 mm-square sample piece from the sputtering target, followed by pulverizing to prepare a pulverized product; (2) classifying the pulverized product using sieves of 106 ?m and 300 ?m in opening size and collecting a powder that has passed through the 300 ?m sieve and remained on the 106 ?m sieve; (3) immersing the powder in aqua regia heated to 200° C. to prepare a residue-containing solution in which the powder has been dissolved; (4) filtering the residue-containing solution through a 5A filter paper specified in JIS P 3801 and drying a residue on the filter paper at 80° C.Type: ApplicationFiled: April 7, 2020Publication date: November 10, 2022Inventors: Takamichi Yamamoto, Masahiro Nishiura, Kenta Kurose, Hironori Kobayashi, Takanobu Miyashita, Tomoko Matsuda
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Patent number: 11474711Abstract: A circuit device 10 includes a register 30, an access control circuit 20 that controls access to a nonvolatile memory 70 and loads setting data of the circuit device 10 stored in the nonvolatile memory 70 in the register 30, and an error detection circuit 40. The access control circuit 20 performs a refresh operation that reloads the setting data stored in the nonvolatile memory 70 in the register 30. The error detection circuit 40 reads data for comparison that has been reloaded in the register 30 from the register 30, compares the data for comparison that was read with an expected value of the data for comparison, and performs access control error detection based on the comparison result.Type: GrantFiled: May 28, 2019Date of Patent: October 18, 2022Assignee: SEIKO EPSON CORPORATIONInventors: Masahiko Miura, Yuichi Hiwasa, Hironori Kobayashi
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Publication number: 20220302497Abstract: An ion conductive solid comprising an oxide represented by general formula: Li6-x-y-2zY1-x-y-zM1xM2yM3zB3O9 in formula, M1 and M2 are each independently at least one metal element selected from a group of Zr, Ce and Sn, M3 is Nb, and x, y, and z represent real numbers satisfying 0.000?x+y<1.000, 0.000?z?1.000, and 0.000<x+y+z<1.000.Type: ApplicationFiled: June 6, 2022Publication date: September 22, 2022Inventors: Yoshitaka SHIBA, Noriko SAKAMOTO, Kentaro DOGUCHI, Takeshi KOBAYASHI, Toyoki OKUMURA, Hironori KOBAYASHI, Tomonari TAKEUCHI
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Publication number: 20220267892Abstract: A problem of particle generation in an Fe-Pt-BN-based sputtering target having a high relative density is resolved by an approach different from conventional methods. An Fe-Pt-BN-based sputtering target having a relative density of 90% or more and a Vickers hardness of 150 or less can reduce the number of particles generated during magnetron sputtering.Type: ApplicationFiled: May 22, 2020Publication date: August 25, 2022Inventors: Masahiro Nishiura, Takamichi Yamamoto, Kenta Kurose, Hironori Kobayashi, Takanobu Miyashita
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Publication number: 20220260465Abstract: A sample scraping method and a sample scraping device capable of efficiently scraping and collecting a biological tissue section without waste while suppressing contamination is provided. In a sample scraping method for scraping and collecting a biological tissue section held on a slide, the FFPE section held on the slide is heated, and the heated FFPE section is scraped by a blade such that the FFPE section that has been scraped off and remains on the blade is collected in a container.Type: ApplicationFiled: February 15, 2022Publication date: August 18, 2022Applicant: SYSMEX CORPORATIONInventors: Soichi OUE, Yutaka MAEDA, Junyi DING, Takayuki KOSHIHARA, Hironori KOBAYASHI, Yasuhiro KOUCHI
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Publication number: 20220167871Abstract: An information generating apparatus is provided with an acquirer and a controller. The acquirer is configured to acquire respiratory waveform data about respiratory pressure of a subject. The controller is configured to compare the respiratory waveform data acquired by the acquirer with preset respiratory reference waveform data, so as to generate respiratory depth information representing respiratory depth of the respiratory waveform data with respect to the respiratory reference waveform data.Type: ApplicationFiled: November 18, 2021Publication date: June 2, 2022Inventors: Takayuki SUGIYAMA, Hironori KOBAYASHI, Kazuri HIGASHI, Ryota AUCHI
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Publication number: 20210382339Abstract: A liquid crystal device includes a liquid crystal panel and a liquid crystal driver. The liquid crystal panel includes a segment electrode, a segment signal line connected to the segment electrode, and a segment signal line connected to the segment electrode. The liquid crystal driver includes a segment terminal to be connected to the segment signal line, a segment driving circuit that outputs a segment driving signal to the segment terminal, a segment terminal to be connected to the segment signal line, and an anomalous segment detection circuit that detects anomalous driving of the segment electrode based on a segment monitoring signal that is input to the segment terminal from the segment electrode via the segment signal line.Type: ApplicationFiled: August 19, 2021Publication date: December 9, 2021Applicant: SEIKO EPSON CORPORATIONInventors: Hironori KOBAYASHI, Norichika MURAKI