Patents by Inventor Hiroshi Koriyama

Hiroshi Koriyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10695420
    Abstract: The present invention provides a combination preparation for inducing a specific immune response to an antigenic peptide, which contains (I) the antigenic peptide, and (II) an expression vector encoding a chimeric hepatitis B virus core antigen polypeptide, into which the antigenic peptide has been inserted or added, wherein said antigenic peptide is inserted in a region of amino acid residues 74-87 or 130-138 of the hepatitis B virus core antigen polypeptide, or added to the N-terminal or C-terminal of the hepatitis B virus core antigen polypeptide, wherein the antigenic peptide of (I) and the expression vector of (II) are substantially simultaneously administered to a subject.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: June 30, 2020
    Assignees: ANGES, INC., OSAKA UNIVERSITY, DS PHARMA ANIMAL HEALTH CO., LTD.
    Inventors: Hironori Nakagami, Ryuichi Morishita, Hiroshi Koriyama, Hideki Tomioka, Kenji Naohara
  • Publication number: 20190365859
    Abstract: The present invention provides a preventive or therapeutic agent for an inflammatory skin disease, such as psoriasis, the agent comprising an oligopeptide as an active ingredient. More specifically, the invention provides a preventive or therapeutic agent for an inflammatory skin disease, the agent comprising an oligopeptide consisting of an amino acid sequence containing a DE loop sequence of RANKL protein and a ?-strand D sequence of RANKL protein placed adjacent to the N-terminal side of the DE loop sequence.
    Type: Application
    Filed: November 7, 2017
    Publication date: December 5, 2019
    Inventors: Munehisa Shimamura, Hironori Nakagami, Yuka Ikeda, Ryuichi Morishita, Hiroshi Koriyama
  • Patent number: 10233215
    Abstract: The invention provides a peptide and an immunostimulant or hair grower containing the peptide as an active ingredient, as well as a method for hair growth or regrowth promotion by administering an effective amount of the peptide to a mammal. The peptide has 23 or less amino acids and includes the amino acid sequence LHRLKRLRKRL (SEQ ID NO: 1), preferably the amino acid sequence LHRLKRLRKRLK (SEQ ID NO: 9).
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: March 19, 2019
    Assignee: OSAKA UNIVERSITY
    Inventors: Hironori Nakagami, Ryuichi Morishita, Hiroshi Koriyama, Akiko Tenma
  • Publication number: 20190002505
    Abstract: The invention provides a peptide and an immunostimulant or hair grower containing the peptide as an active ingredient, as well as a method for hair growth or regrowth promotion by administering an effective amount of the peptide to a mammal. The peptide has 23 or less amino acids and includes the amino acid sequence LHRLKRLRKRL (SEQ ID NO: 1), preferably the amino acid sequence LHRLKRLRKRLK (SEQ ID NO: 9).
    Type: Application
    Filed: September 18, 2018
    Publication date: January 3, 2019
    Applicant: OSAKA UNIVERSITY
    Inventors: Hironori Nakagami, Ryuichi Morishita, Hiroshi Koriyama, Akiko Tenma
  • Patent number: 10112978
    Abstract: An object of the present invention is to provide a novel peptide and a novel immunostimulant or hair grower containing the peptide as an active ingredient. The present invention provides a peptide of 23 or less amino acids comprising the amino acid sequence LHRLKRLRKRL (SEQ ID NO: 1), preferably the amino acid sequence LHRLKRLRKRLK (SEQ ID NO: 9), and also provides an immunostimulant containing the peptide, a vaccine adjuvant containing the peptide, a vaccine composition containing the peptide, and a hair grower containing the peptide.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: October 30, 2018
    Assignee: Osaka University
    Inventors: Hironori Nakagami, Ryuichi Morishita, Hiroshi Koriyama, Akiko Tenma
  • Patent number: 9913886
    Abstract: The present invention provides an agent for the treatment or prophylaxis of arteriosclerosis comprising an expression vector encoding a chimeric Hepatitis B virus core antigen polypeptide inserted with an amino acid sequence containing a specific epitope of apolipoprotein (a), wherein the amino acid sequence containing the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis B virus core antigen polypeptide.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: March 13, 2018
    Assignee: AnGes, Inc.
    Inventors: Mariko Kyutoku, Hironori Nakagami, Hiroshi Koriyama, Futoshi Nakagami, Ryuichi Morishita
  • Publication number: 20170275336
    Abstract: An object of the present invention is to provide a novel peptide and a novel immunostimulant or hair grower containing the peptide as an active ingredient. The present invention provides a peptide of 23 or less amino acids comprising the amino acid sequence LHRLKRLRKRL (SEQ ID NO: 1), preferably the amino acid sequence LHRLKRLRKRLK (SEQ ID NO: 9), and also provides an immunostimulant containing the peptide, a vaccine adjuvant containing the peptide, a vaccine composition containing the peptide, and a hair grower containing the peptide.
    Type: Application
    Filed: September 25, 2015
    Publication date: September 28, 2017
    Applicant: Osaka University
    Inventors: Hironori NAKAGAMI, Ryuichi MORISHITA, Hiroshi KORIYAMA, Akiko TENMA
  • Publication number: 20170258895
    Abstract: The present invention provides a combination preparation for inducing a specific immune response to an antigenic peptide, which contains (I) the antigenic peptide, and (II) an expression vector encoding a chimeric hepatitis B virus core antigen polypeptide, into which the antigenic peptide has been inserted or added, wherein said antigenic peptide is inserted in a region of amino acid residues 74-87 or 130-138 of the hepatitis B virus core antigen polypeptide, or added to the N-terminal or C-terminal of the hepatitis B virus core antigen polypeptide, wherein the antigenic peptide of (I) and the expression vector of (II) are substantially simultaneously administered to a subject.
    Type: Application
    Filed: November 20, 2015
    Publication date: September 14, 2017
    Applicants: ANGES MG, INC., OSAKA UNIVERSITY, DS PHARMA ANIMAL HEALTH CO., LTD.
    Inventors: Hironori NAKAGAMI, Ryuichi MORISHITA, Hiroshi KORIYAMA, Hideki TOMIOKA, Kenji NAOHARA
  • Publication number: 20160319013
    Abstract: The present invention provides a vaccine against IL-17A, which uses, as an immunogen, a polypeptide containing the amino acid sequence shown in SEQ ID NO: 1, or an amino acid sequence derived from a non-human mammal, which corresponds to SEQ ID NO: 1, a prophylactic or therapeutic agent containing the vaccine for diseases involving IL-17A as an aggravation factor, and the like.
    Type: Application
    Filed: December 26, 2014
    Publication date: November 3, 2016
    Applicant: OSAKA UNIVERSITY
    Inventors: Hiroshi KORIYAMA, Hironori NAKAGAMI, Ryuichi MORISHITA
  • Publication number: 20160303211
    Abstract: The present invention provides an agent for the treatment or prophylaxis of arteriosclerosis comprising an expression vector encoding a chimeric Hepatitis B virus core antigen polypeptide inserted with an amino acid sequence containing a specific epitope of apolipoprotein (a), wherein the amino acid sequence containing the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis B virus core antigen polypeptide.
    Type: Application
    Filed: July 1, 2016
    Publication date: October 20, 2016
    Applicant: AnGesMG, Inc.
    Inventors: Mariko KYUTOKU, Hironori NAKAGAMI, Hiroshi KORIYAMA, Futoshi NAKAGAMI, Ryuichi MORISHITA
  • Patent number: 9446120
    Abstract: The present invention provides a therapeutic or improving agent for a lifestyle-related disease, containing an expression vector encoding a chimeric Hepatitis B virus core antigen polypeptide inserted with an amino acid sequence containing a specific epitope of the lifestyle-related disease-related factor, wherein the amino acid sequence containing the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis B virus core antigen polypeptide.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: September 20, 2016
    Assignees: Osaka University, Anges MG, Inc.
    Inventors: Ryuichi Morishita, Hironori Nakagami, Hiroshi Koriyama, Futoshi Nakagami, Natsuki Yoshida
  • Publication number: 20160193308
    Abstract: The present invention provides a vaccine for the prophylaxis or treatment of diabetes using a polypeptide containing the amino acid sequence shown by SEQ ID NO: 2 or an amino acid sequence of a non-human mammal, which corresponds to SEQ ID NO: 2, and the like as an immunogen, which induces a neutralizing antibody to DPP-4, and a prophylactic or therapeutic agent for diabetes, which contains a DDP-4 neutralizing antibody that recognizes a partial amino acid sequence of the aforementioned DDP-4.
    Type: Application
    Filed: August 27, 2014
    Publication date: July 7, 2016
    Applicant: OSAKA UNIVERSITY
    Inventors: Hironori NAKAGAMI, Ryuichi MORISHITA, Hiroshi KORIYAMA
  • Publication number: 20140099335
    Abstract: The present invention provides a therapeutic or improving agent for a lifestyle-related disease, containing an expression vector encoding a chimeric Hepatitis B virus core antigen polypeptide inserted with an amino acid sequence containing a specific epitope of the lifestyle-related disease-related factor, wherein the amino acid sequence containing the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis B virus core antigen polypeptide.
    Type: Application
    Filed: April 13, 2012
    Publication date: April 10, 2014
    Applicants: ANGES MG, INC., OSAKA UNIVERSITY
    Inventors: Ryuichi Morishita, Hironori Nakagami, Hiroshi Koriyama, Futoshi Nakagami, Natsuki Yoshida
  • Publication number: 20140086944
    Abstract: The present invention provides an agent for the treatment or prophylaxis of arteriosclerosis comprising an expression vector encoding a chimeric Hepatitis B virus core antigen polypeptide inserted with an amino acid sequence containing a specific epitope of apolipoprotein (a), wherein the amino acid sequence containing the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis B virus core antigen polypeptide.
    Type: Application
    Filed: September 20, 2013
    Publication date: March 27, 2014
    Inventors: Mariko KYUTOKU, Hironori NAKAGAMI, Hiroshi KORIYAMA, Futoshi NAKAGAMI, Ryuichi MORISHITA
  • Patent number: 6884498
    Abstract: The present invention provides a rubber blanket for an offset printing, comprising a surface rubber layer, a first fabric layer, a compressible layer and a second fabric layer, wherein the thickness of the blanket falls within a range of between 1.65 mm and 3 mm, the first fabric layer is a plain weave having a thickness falling within a range of between 0.2 mm and 0.35 mm, the second fabric layer is a plain weave having a thickness falling within a range of between 0.35 mm and 0.55 mm, a tensile strength not lower than 50 kgf/cm, and an elongation at break not higher than 7.5%, and the compressible layer has a thickness falling within a range of between 0.5 mm and 2.15 mm.
    Type: Grant
    Filed: June 25, 2003
    Date of Patent: April 26, 2005
    Assignee: Kinyosha Co., Ltd.
    Inventors: Yoshiharu Ogawa, Hiroshi Koriyama
  • Publication number: 20040001935
    Abstract: The present invention provides a rubber blanket for an offset printing, comprising a surface rubber layer, a first fabric layer, a compressible layer and a second fabric layer, wherein the thickness of the blanket falls within a range of between 1.65 mm and 3 mm, the first fabric layer is a plain weave having a thickness falling within a range of between 0.2 mm and 0.35 mm, the second fabric layer is a plain weave having a thickness falling within a range of between 0.35 mm and 0.55 mm, a tensile strength not lower than 50 kgf/cm, and an elongation at break not higher than 7.5%, and the compressible layer has a thickness falling within a range of between 0.5 mm and 2.15 mm.
    Type: Application
    Filed: June 25, 2003
    Publication date: January 1, 2004
    Applicant: Kinyosha Co., Ltd.
    Inventors: Yoshiharu Ogawa, Hiroshi Koriyama
  • Patent number: 6212030
    Abstract: A clamping structure for disk drive for receiving a disk includes a spindle hub, a spacer, and a clamp ring. The spindle hub has a flange at a first end thereof. The flange has a first protruding portion. The discs are stacked on the first protruding portion. The first spacer is interposed between adjacent ones of the disks. The clamp ring is fixed to a second end of the spindle hub. The clamp ring has a second protruding portion for biasing the disks toward the flange of the spindle hub. In a process of forming a holder arm of the disk drive, the tip of a holder arm is contoured by wire cutting method after the holder armed is roughly formed from a metal body. In the wire cutting method, a voltage is placed between the metal body and the wire. The tip of the holder is contoured by the wire by bringing the wire into contact with the metal body.
    Type: Grant
    Filed: January 31, 1995
    Date of Patent: April 3, 2001
    Assignee: NEC Corporation
    Inventors: Hiroshi Koriyama, Norio Tagawa, Kenji Itoh, Misa Iwamoto, Takahiro Suzuki
  • Patent number: 5901020
    Abstract: A magnetic disk drive capable of reducing the influence of a tension ascribable to the forming of a flexible printed circuit (FPC), which transfers the output signal of a magnetic head, on a carriage. The curved configuration and arrangement of the FPC are changed to minimize the tension ascribable to the FPC even when the carriage seeks the inner or outer peripheral portion of a magnetic disk.
    Type: Grant
    Filed: January 12, 1998
    Date of Patent: May 4, 1999
    Assignee: NEC Corporation
    Inventor: Hiroshi Koriyama
  • Patent number: 5805385
    Abstract: A magnetic disk device has a spindle shaft rotatably supported by bearings, a plurality of magnetic disks directly mounted on an outer peripheral side of the spindle shaft and being stacked in an axial direction of the spindle shaft, a plurality of spacer rings directly mounted on the outer peripheral side of the spindle shaft and respectively interposed between the plurality of magnetic disks, and a clamp ring mounted on the top of the spindle shaft for tightly fixing the plurality of magnetic disks and the plurality of spacer rings to the spindle shaft. The device also has a center shaft provided with inner race members which are in contact with inner peripheral surfaces of bearings, an arm holder including a cylinder member formed in a center portion thereof and arm members connected at one end portion to magnetic heads corresponding to respective magnetic disks and at another end portion to the outer peripheral side of the cylinder member.
    Type: Grant
    Filed: March 24, 1995
    Date of Patent: September 8, 1998
    Assignee: NEC Corporation
    Inventor: Hiroshi Koriyama
  • Patent number: 5745326
    Abstract: A magnetic disk drive capable of reducing the influence of a tension ascribable to the forming of a flexible printed circuit (FPC), which transfers the output signal of a magnetic head, on a carriage. The curved configuration and arrangement of the FPC are changed to minimize the tension ascribable to the FPC even when the carriage seeks the inner or outer peripheral portion of a magnetic disk.
    Type: Grant
    Filed: October 21, 1996
    Date of Patent: April 28, 1998
    Assignee: NEC Corporation
    Inventor: Hiroshi Koriyama