Patents by Inventor Hiroyoshi Nanba
Hiroyoshi Nanba has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10494338Abstract: The present invention relates to a novel prostaglandin derivative having an alkynyl group on ?-chain, particularly, a novel prostaglandin derivative having a double bond at the 2-position and an alkynyl group on the ?-chain and a medicament containing the compound as an active ingredient. According to the present invention, a compound represented by the formula (1) or a pharmaceutically acceptable salt thereof; wherein each symbol is as defined in the present specification, or a cyclodextrin clathrate compound thereof, and a medicament containing the compound as an active ingredient, particularly, a medicament for the prophylaxis or treatment of a blood flow disorder associated with spinal canal stenosis or chronic arterial occlusion, can be provided.Type: GrantFiled: May 9, 2017Date of Patent: December 3, 2019Assignees: AGC INC., NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Arata Yasuda, Yasushi Matsumura, Kazuyoshi Sawada, Hiroyoshi Nanba, Kazuki Taguchi
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Publication number: 20190135743Abstract: The present invention relates to a novel prostaglandin derivative having an alkynyl group on ?-chain, particularly, a novel prostaglandin derivative having a double bond at the 2-position and an alkynyl group on the ?-chain and a medicament containing the compound as an active ingredient. According to the present invention, a compound represented by the formula (1) or a pharmaceutically acceptable salt thereof; wherein each symbol is as defined in the present specification, or a cyclodextrin clathrate compound thereof, and a medicament containing the compound as an active ingredient, particularly, a medicament for the prophylaxis or treatment of a blood flow disorder associated with spinal canal stenosis or chronic arterial occlusion, can be provided.Type: ApplicationFiled: May 9, 2017Publication date: May 9, 2019Applicants: AGC INC., NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Arata YASUDA, Yasushi MATSUMURA, Kazuyoshi SAWADA, Hiroyoshi NANBA, Kazuki TAGUCHI
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Patent number: 9540338Abstract: A cinnamic acid amide derivative having an excellent analgesic action is disclosed herein. The cinnamic acid amide derivative shows excellent analgesic actions to not only a nociceptive pain model animal, but also a neuropathic pain model animal, which is very useful as an agent for treating various pain diseases showing acute or chronic pains or neuropathic pains. The cinnamic acid amide derivative may be a compound represented by formula (I).Type: GrantFiled: December 27, 2013Date of Patent: January 10, 2017Assignee: NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Tomohiro Ookubo, Ko Nakamura, Yoshitaka Nakazawa, Hiroyoshi Nanba, Hiroyuki Yoshida
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Publication number: 20150322024Abstract: The present invention provides a cinnamic acid amide derivative having an excellent analgesic action. The cinnamic acid amide derivative of the present invention is a compound showing excellent analgesic actions to not only a nociceptive pain model animal but also a neuropathic pain model animal, which is very useful as an agent for treating various pain diseases showing acute or chronic pains or neuropathic pains.Type: ApplicationFiled: December 27, 2013Publication date: November 12, 2015Applicant: NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Tomohiro OOKUBO, Ko NAKAMURA, Yoshitaka NAKAZAWA, Hiroyoshi NANBA, Hiroyuki YOSHIDA
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Patent number: 9150510Abstract: The amino acid derivative of the present invention provides a novel compound that shows excellent analgesic action. The amino acid derivative of the present invention is a novel compound that shows excellent analgesic action to not only a model animal for nociceptive pains but also a model animal for neuropathic pains, so that the amino acid derivative is very useful as a drug for treating various pain diseases.Type: GrantFiled: September 17, 2009Date of Patent: October 6, 2015Assignee: NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Tomohiro Ookubo, Ko Nakamura, Hiroyoshi Nanba, Hiroyuki Yoshida, Yoshitaka Nakazawa
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Patent number: 8324261Abstract: The present invention is to provide a novel compound which is useful as a pharmaceutical agent such as an analgesic. The present invention is to provide the novel histidine derivative having an excellent analgesic action and the like. The compound of the present invention has a very high intermigration into the blood upon oral administration and is very useful as a pharmaceutical agent, especially an analgesic for the treatment of acute or chronic pain diseases and of neuropathic pain diseases.Type: GrantFiled: July 18, 2008Date of Patent: December 4, 2012Assignee: Nippon Zoki Pharmaceutical Co., Ltd.Inventors: Yoshitaka Nakazawa, Kenji Mitsuda, Tomohiro Ookubo, Teppei Seguchi, Hiroyoshi Nanba
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Publication number: 20110172442Abstract: The amino acid derivative of the present invention provides a novel compound that shows excellent analgesic action. The amino acid derivative of the present invention is a novel compound that shows excellent analgesic action to not only a model animal for nociceptive pains but also a model animal for neuropathic pains, so that the amino acid derivative is very useful as a drug for treating various pain diseases.Type: ApplicationFiled: September 17, 2009Publication date: July 14, 2011Applicant: NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Tomohiro Ookubo, Ko Nakamura, Hiroyoshi Nanba, Hiroyuki Yoshida, Yoshitaka Nakazawa
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Publication number: 20100152459Abstract: The present invention is to provide a novel compound which is useful as a pharmaceutical agent such as an analgesic. The present invention is to provide the novel histidine derivative having an excellent analgesic action and the like. The compound of the present invention has a very high intermigration into the blood upon oral administration and is very useful as a pharmaceutical agent, especially an analgesic for the treatment of acute or chronic pain diseases and of neuropathic pain diseases.Type: ApplicationFiled: July 18, 2008Publication date: June 17, 2010Applicant: NIPPON ZOKI PHARMACEUTICAL CO., LTD.Inventors: Yoshitaka Nakazawa, Kenji Mitsuda, Tomohiro Ookubo, Teppei Seguchi, Hiroyoshi Nanba