Patents by Inventor Hiroyuki Ikemoto
Hiroyuki Ikemoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11767491Abstract: A method for producing an EPA alkyl ester-containing composition includes: preparing a raw material oil containing an EPA alkyl ester in an amount of from 50 to 92% by mass in the total fatty acids, in which a mass ratio of a DHA alkyl ester to the EPA alkyl ester contained in the raw material oil is 3.3% by mass or less and further a ratio of trans isomers in the EPA alkyl ester contained in the raw material oil is 2% by mass or less; bringing the raw material oil into contact with an aqueous solution containing a silver salt; recovering the aqueous solution containing the silver salt brought into contact with the raw material oil; bringing the recovered aqueous solution containing the silver salt into contact with an organic solvent; and recovering the organic solvent brought into contact with the aqueous solution containing the silver salt.Type: GrantFiled: March 26, 2020Date of Patent: September 26, 2023Assignee: NISSHIN PHARMA INC.Inventors: Hiroyuki Ikemoto, Junichi Node, Kenji Takemoto
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Publication number: 20220169949Abstract: A method for producing an EPA alkyl ester-containing composition includes: preparing a raw material oil containing an EPA alkyl ester in an amount of from 50 to 92% by mass in the total fatty acids, in which a mass ratio of a DHA alkyl ester to the EPA alkyl ester contained in the raw material oil is 3.3% by mass or less and further a ratio of trans isomers in the EPA alkyl ester contained in the raw material oil is 2% by mass or less; bringing the raw material oil into contact with an aqueous solution containing a silver salt; recovering the aqueous solution containing the silver salt brought into contact with the raw material oil; bringing the recovered aqueous solution containing the silver salt into contact with an organic solvent; and recovering the organic solvent brought into contact with the aqueous solution containing the silver salt.Type: ApplicationFiled: March 26, 2020Publication date: June 2, 2022Applicant: NISSHIN PHARMA INC.Inventors: Hiroyuki IKEMOTO, Junichi NODE, Kenji TAKEMOTO
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Patent number: 10899994Abstract: Provided is a method for producing a polyunsaturated fatty acid while suppressing deterioration of a silver salt solution. A method for producing a polyunsaturated fatty acid-containing composition, the method comprising: supplying a raw material solution comprising an alkyl ester of polyunsaturated fatty acid and an aqueous solution comprising a silver salt to a flow channel mixer to contact the raw material solution with the aqueous solution; and collecting the aqueous solution comprising the silver salt which has been contacted with the raw material solution, in which the supplying the aqueous solution comprising the silver salt to the flow channel mixer and the collecting the same are performed concurrently.Type: GrantFiled: June 14, 2018Date of Patent: January 26, 2021Assignee: NISSHIN PHARMA INC.Inventors: Hiroyuki Ikemoto, Kenji Takemoto, Masataka Harata, Shingo Nonaka, Hideki Kanai
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Publication number: 20200172829Abstract: Provided is a method for producing a polyunsaturated fatty acid while suppressing deterioration of a silver salt solution. A method for producing a polyunsaturated fatty acid-containing composition, the method comprising: supplying a raw material solution comprising an alkyl ester of polyunsaturated fatty acid and an aqueous solution comprising a silver salt to a flow channel mixer to contact the raw material solution with the aqueous solution; and collecting the aqueous solution comprising the silver salt which has been contacted with the raw material solution, in which the supplying the aqueous solution comprising the silver salt to the flow channel mixer and the collecting the same are performed concurrently.Type: ApplicationFiled: June 14, 2018Publication date: June 4, 2020Applicant: NISSHIN PHARMA INC.Inventors: Hiroyuki IKEMOTO, Kenji TAKEMOTO, Masataka HARATA, Shingo NONAKA, Hideki KANAI
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Patent number: 10597607Abstract: Provided is a method for producing a polyunsaturated fatty acid while preventing deterioration of a silver salt solution. A method for producing a composition comprising a polyunsaturated fatty acid, comprising: supplying an aqueous solution comprising a silver salt into a reaction vessel to contact the aqueous solution with a raw material solution comprising an alkyl ester of the polyunsaturated fatty acid; and collecting the aqueous solution comprising the silver salt which has been contacted with the raw material solution from the reaction vessel, wherein the supply of the aqueous solution comprising the silver salt into the reaction vessel and the collection of the aqueous solution comprising the silver salt from the reaction vessel are carried out concurrently with each other.Type: GrantFiled: May 1, 2017Date of Patent: March 24, 2020Assignee: NISSHIN PHARMA INC.Inventors: Masataka Harata, Shingo Nonaka, Hideki Kanai, Hiroyuki Ikemoto, Kenji Takemoto
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Publication number: 20190144780Abstract: Provided is a method for producing a polyunsaturated fatty acid while preventing deterioration of a silver salt solution. A method for producing a composition comprising a polyunsaturated fatty acid, comprising: supplying an aqueous solution comprising a silver salt into a reaction vessel to contact the aqueous solution with a raw material solution comprising an alkyl ester of the polyunsaturated fatty acid; and collecting the aqueous solution comprising the silver salt which has been contacted with the raw material solution from the reaction vessel, wherein the supply of the aqueous solution comprising the silver salt into the reaction vessel and the collection of the aqueous solution comprising the silver salt from the reaction vessel are carried out concurrently with each other.Type: ApplicationFiled: May 1, 2017Publication date: May 16, 2019Applicant: NISSHIN PHARMA INC.Inventors: Masataka HARATA, Shingo NONAKA, Hideki KANAI, Hiroyuki IKEMOTO, Kenji TAKEMOTO
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Patent number: 8357380Abstract: The coenzyme Q10-containing liquid composition is obtained by dispersing and emulsifying coenzyme Q10 in an aqueous liquid containing a water-soluble substance consisting of octenylsuccinate starch and dextrin, and glycerin. The liquid composition may be dried to prepare a coenzyme Q10-containing solid composition.Type: GrantFiled: January 11, 2012Date of Patent: January 22, 2013Assignee: Nisshin Pharma Inc.Inventors: Hiroyuki Ikemoto, Tsuyoshi Minemura
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Publication number: 20120107374Abstract: The coenzyme Q10-containing liquid composition is obtained by dispersing and emulsifying coenzyme Q10 in an aqueous liquid containing a water-soluble substance consisting of octenylsuccinate starch and dextrin, and glycerin. The liquid composition may be dried to prepare a coenzyme Q10-containing solid composition.Type: ApplicationFiled: January 11, 2012Publication date: May 3, 2012Inventors: HIROYUKI IKEMOTO, Tsuyoushi Minemura
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Patent number: 8119113Abstract: There is provided a coenzyme Q10-containing composition having a high coenzyme Q10 content and excellent stability and bioavailability of coenzyme Q10, without using synthetic emulsifiers such as glycerin fatty acid esters, polyglycerin fatty acid esters, organic acid monoglycerides or sucrose fatty acid esters. The coenzyme Q10-containing liquid composition is obtained by dispersing and emulsifying coenzyme Q10 in an aqueous liquid containing a water-soluble substance consisting of octenylsuccinate starch and dextrin, and glycerin. The liquid composition may be dried to prepare a coenzyme Q10-containing solid composition.Type: GrantFiled: August 18, 2005Date of Patent: February 21, 2012Assignee: Nisshin Pharma, Inc.Inventors: Hiroyuki Ikemoto, Tsuyoshi Minemura
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Patent number: 7628595Abstract: A gas vane pump wherein a lubricant is intermittently introduced into a housing during rotation of a rotor, through a supply passage formed through the housing and the rotor, and the relative position between the rotor having a diametric hole and the housing having a communication groove is determined such that when the rotor is at an angular position in the middle of a predetermined angular range relative to the housing and the hole is in communication with the groove, a point of contact between a vane movably held by the rotor and the inner circumferential surface of the housing is located at the lowest position of the inner circumferential surface. When the rotor is stopped within the predetermined angular range, the vane divides the remaining lubricant into two portions, which are discharged at different times, making it possible to reduce the load on the vane upon restarting the pump.Type: GrantFiled: March 8, 2005Date of Patent: December 8, 2009Assignees: Toyota Jidosha Kabushiki Kaisha, Luk Automobiltechnik GmbH & Co. KGInventors: Kohei Ono, Hiroyuki Ikemoto, Junichi Tanoue, Ulrich Hiltemann, Christoph Heidemeyer
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Publication number: 20080248013Abstract: There is provided a coenzyme Q10-containing composition having a high coenzyme Q10 content and excellent stability and bioavailability of coenzyme Q10, without using synthetic emulsifiers such as glycerin fatty acid esters, polyglycerin fatty acid esters, organic acid monoglycerides or sucrose fatty acid esters. The coenzyme Q10-containing liquid composition is obtained by dispersing and emulsifying coenzyme Q10 in an aqueous liquid containing a water-soluble substance consisting of octenylsuccinate starch and dextrin, and glycerin. The liquid composition may be dried to prepare a coenzyme Q10-containing solid composition.Type: ApplicationFiled: August 18, 2005Publication date: October 9, 2008Applicant: NISSHIN PHARMA INC.,Inventors: Hiroyuki Ikemoto, Tsuyoshi Minemura
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Publication number: 20080240962Abstract: A gas vane pump wherein a lubricant is intermittently introduced into a housing 10 during rotation of a rotor 40, through a lubricant supply passage 100 formed through the housing and the rotor, and the relative position between the rotor having a diametric hole 112 and the housing having a communication groove 130 is determined such that when the rotor 40 is placed at an angular position which is in the middle of a predetermined angular range relative to the housing 10 and in which the hole 112 is in communication with the groove 130, a point of contact between a vane 70 movably held by the rotor and the inner circumferential surface of the housing 10 is located at the lowest position of the inner circumferential surface, so that when the rotor 40 is stopped at an angular position within the predetermined angular range, the vane 70 divides the remaining lubricant mass into two portions, which are discharged at respective two different times one after the other, making it possible to reduce the load acting onType: ApplicationFiled: March 8, 2005Publication date: October 2, 2008Applicants: Toyota Jidosha Kabushiki Kaisha, LUK AUTOMOBILTECHNIK GMBH & CO. KGInventors: Kohei Ono, Hiroyuki Ikemoto, Junichi Tanoue, Ulrich Hiltemann, Christoph Heidemeyer
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Publication number: 20080159708Abstract: A video contents display apparatus include a display generation unit for: generating a predetermined number of static images by considering a time of lapse from information about recorded video contents; converting a static image other than at least one specified static image into an image reduced in a predetermined format from the predetermined number of generated static images; and displaying a sequence of images by arranging the at least one static image and the other static image along a predetermined path on a screen by considering the time of lapse.Type: ApplicationFiled: December 26, 2007Publication date: July 3, 2008Applicant: Kabushiki Kaisha ToshibaInventors: Hisashi Kazama, Takahisa Yoneyama, Takashi Nakamura, Goh Uemura, Masayuki Horikawa, Tatsuya Uehara, Koichi Awazu, Hiroyuki Ikemoto
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Patent number: 6858234Abstract: The process for the preparation of amylase inhibitor including the steps of: (A) obtaining an extract solution containing the amylase inhibitor; (B) insolubilizing the amylase inhibitor by salting out by addition of a salt or salts to the solution obtained in the step (A) and recovering the insolubilized substance resulting from the salting out; and (C) directly drying the insolubilized substance recovered in the step (B) or dissolving the insolubilized substance in water to prepare an aqueous solution, and desalting and drying the aqueous solution to recover the amylase inhibitor, whereby, an amylase inhibitor in high concentrations 0.19 AI is prepared that shows highly inhibitive activity against the amylase in high yield and with good productivity.Type: GrantFiled: January 23, 2003Date of Patent: February 22, 2005Assignees: Nisshin Pharma Inc., Nagata Sangyo Co., Ltd.Inventors: Ryuji Murayama, Takeo Kanafuji, Yasuhito Muranaka, Rumiko Muranaka, Kazuo Sato, Akira Sekigawa, Kazuhiko Yamada, Yoshio Suzuki, Hiroyuki Ikemoto
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Publication number: 20030186409Abstract: The process for the preparation of amylase inhibitor comprises:Type: ApplicationFiled: January 23, 2003Publication date: October 2, 2003Applicant: NISSHIN PHARMA INC.Inventors: Ryuji Murayama, Takeo Kanafuji, Yasuhito Muranaka, Rumiko Muranaka, Kazuo Sato, Akira Sekigawa, Kazuhiko Yamada, Yoshio Suzuki, Hiroyuki Ikemoto
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Patent number: 6583692Abstract: A filter that produces a multiple passband response as a single device. The multiple passband filter has a plurality of poles concentrated in a desired passband of the filter. A plurality of zeroes are located outside of the desired passband to form passband edges. One or more zeroes are located in a central portion of the passband to form multiple passbands within the passband edges.Type: GrantFiled: May 8, 2001Date of Patent: June 24, 2003Assignee: Space Systems/Loral, Inc.Inventors: Stephen C. Holme, Hiroyuki Ikemoto
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Publication number: 20020167379Abstract: A filter that produces a multiple passband response as a single device. The multiple passband filter has a plurality of poles concentrated in a desired passband of the filter. A plurality of zeroes are located outside of the desired passband to form passband edges. One or more zeroes are located in a central portion of the passband to form multiple passbands within the passband edges.Type: ApplicationFiled: May 8, 2001Publication date: November 14, 2002Inventors: Stephen C. Holme, Hiroyuki Ikemoto
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Patent number: 6011069Abstract: There is disclosed a multidrug resistance inhibitor for overcoming a multidrug resistance of cancer, or an agent for enhancing the activity of anti-cancer agents, which comprises as an active ingredient a compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein n is an integer of 5 to 12,R.sub.1 and R.sub.2 are each independently benzyl, of which a phenyl ring may be substituted by 1 to 5 substituents selected from hydroxy, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy and halogen, and/or by methylenedioxy, with the proviso that R.sub.1 and R.sub.Type: GrantFiled: December 17, 1996Date of Patent: January 4, 2000Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Kohei Inomata, Toshihiro Takahashi, Hitoshi Inoue, Makoto Yanai, Hiroyuki Yamazaki, Masashi Suzuki, Tsutomu Takasawa, Kouji Kawamura, Norio Oshida, Hiroyuki Ikemoto, Takao Kishiye
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Patent number: 5969717Abstract: A display component selecting system comprises unit for inputting a screen input/output data item to be inputted and/or outputted on a display screen and use information representing a use for the data item by at least one attribute, unit, which includes a table showing the correspondence between various attributes and various display components, for holding a selection rule used to select a suitable display component in accordance with the inputted use information, and unit for selecting a display component associated with the inputted screen input/output data item in accordance with the selection rule.Type: GrantFiled: July 25, 1997Date of Patent: October 19, 1999Assignee: Kabushiki Kaisha ToshibaInventor: Hiroyuki Ikemoto
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Patent number: 5756475Abstract: Isoprene derivatives of formula (I) ##STR1## wherein m is an integer of 0 to 3,n is an integer of 5 to 12,A is cyclo(C.sub.3 -C.sub.6)alkylene, phenylene, fluorenylene, pyrrolidinylene, piperazinylene, 9-aza-3-oxabicyclo?3.3.1!-nonylene,R.sub.1 and R.sub.2 are each independently benzyl, of which a phenyl ring may be substituted by 1 to 5 substituents selected from the group consisting of hydroxy, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy and halogen,X is a single bond or a divalent radical of --(CH.sub.2).sub.p NH--,p is an integer of 0 to 3, or a pharmaceutically acceptable salt thereof. Those compounds are useful as multidrug resistance inhibitors for overcoming multidrug resistance of cancer and agents for enhancing an activity of anti-cancer agents.Type: GrantFiled: January 30, 1997Date of Patent: May 26, 1998Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Kohei Inomata, Toshihiro Takahashi, Hitoshi Inoue, Makoto Yanai, Hiroyuki Yamazaki, Masashi Suzuki, Tsutomu Takasawa, Kouji Kawamura, Norio Oshida, Hiroyuki Ikemoto, Takao Kishiye