Abstract: The invention provides a rubber composition prepared by mixing, per 100 parts by mass of a rubber component comprising at least 50% by mass of a diene-based rubber, from 20 to 150 parts by mass of a filler, and from 0.05 to 30 parts by mass of a compound A which has a specific guanidine structure and has a functional group reactive with the diene-based rubber. The rubber composition improves both a high elastic modulus and a low tan ?. The invention also provides a pneumatic tire using the rubber composition.

Abstract: The invention provides a rubber composition prepared by mixing, per 100 parts by mass of a rubber component comprising at least 50% by mass of a diene-based rubber, from 20 to 150 parts by mass of a filler, and from 0.05 to 30 parts by mass of a compound A which has a specific guanidine structure and has a functional group reactive with the diene-based rubber. The rubber composition improves both a high elastic modulus and a low tan ?. The invention also provides a pneumatic tire using the rubber composition.

Abstract: The present invention addresses the problem of providing a block copolymer that has excellent adhesion to a base material and that can impart excellent antithrombogenicity to the base material surface, and providing a medical device comprising the block copolymer. The block copolymer according to the present invention comprises an A block and a B block. The A block is capable of containing intermediate water. The B block is more hydrophobic than the A block. The medical device according to the present invention is obtained by coating a medical device with an antithrombotic coating agent containing the block copolymer.

Abstract: The invention provides a rubber composition prepared by mixing, per 100 parts by mass of the rubber component comprising at least 50% by mass of a diene-based rubber, from 20 to 150 parts by mass of a filler, and from 0.05 to 30 parts by mass of a compound A which has a specific amidine structure and has a functional group reactive with the diene-based rubber. The rubber composition improves both a high elastic modulus and a low tan ?. The invention also provides a pneumatic tire using the rubber composition.

Abstract: The invention provides a rubber composition prepared by mixing, per 100 parts by mass of a rubber component comprising at least 50% by mass of a diene-based rubber, from 20 to 150 parts by mass of a filler, and from 0.05 to 30 parts by mass of a compound A which has a specific guanidine structure and has a functional group reactive with the diene-based rubber. The rubber composition improves both a high elastic modulus and a low tan ?. The invention also provides a pneumatic tire using the rubber composition.

Abstract: The invention provides a rubber composition prepared by mixing, per 100 parts by mass of the rubber component comprising at least 50% by mass of a diene-based rubber, from 20 to 150 parts by mass of a filler, and from 0.05 to 30 parts by mass of a compound A which has a specific amidine structure and has a functional group reactive with the diene-based rubber. The rubber composition improves both a high elastic modulus and a low tan ?. The invention also provides a pneumatic tire using the rubber composition.

Abstract: This invention provides a peptide that comprises an amino acid sequence consisting of 14 to 18 amino acid residues represented by Formula (I) and is capable of binding to human IgA: (SEQ?ID?NO:?1) H-(X1)-V-C-L-S-Y-R-(X2)-(X3)-G-(X4)-P-(X5)-C- (X6)-(X7)-(X8)(I) wherein each X is independently selected from among the following: X1 represents a Gln residue or a Met residue; X2 and X3 each independently represent an arbitrary amino acid residue other than Cys or either or both thereof are deleted; X4 represents an Arg residue or a Gln residue; X5 represents a Val residue or a Thr residue; X6 represents a Phe residue or a Tyr residue; X7 represents a Ser residue or is null; and X8 represents a Leu residue, a Thr residue, or is null, provided that, when X1 represents a Met residue, X7 represents a Ser residue or is null, and X8 is null. The invention also provides a method for purifying or analyzing human IgA using such peptide.

Abstract: Antibacterial hydroxyarylpiperazinocephalosporins of the formula: ##STR1## wherein R.sup.1 is amino or acylamino; R.sup.2 is H or methoxy; R.sup.3 is alkyl; R.sup.4 is --(P--C--Q).sub.n --, where P and Q each are H, alkyl or OH, or P and Q combine to form oxo, and n is 0 or 4; R.sup.5 is substituted or unsubstituted hydroxyaryl; R.sup.6 has a negative charge and is COO, or an anion in combination with an optionally protected carboxy; and X is O, S or S.fwdarw.O; an antibacterial preparation containing the same; a method for killing bacteria and preventing or treating bacterial infection by using the same; and syntheses of the cephalosporins are provided.

Abstract: An antibacterial 3-(alkylcarbamoyloxymethyl)-3-cephem-4-carboxylic acid or its derivatives represented by the following formula ##STR1## (wherein R is hydrogen or an amino-protecting group,R.sup.1 and R.sup.2 each is the same or different 1C to 8C alkyl,R.sup.3 is hydrogen, a salt or ester forming atom or group, andX is sulfur or sulfinyl),a pharmaceutical composition containing the same, a method for treating a bacterial infection with the same, and a method for preparing the same are disclosed.

Abstract: A useful industrial chemical, oxazolinoazetidinylhydroxymethylbutenoic acid derivative (II) can be produced by oxidizing the corresponding oxazolinoazetidinylhalomethylbutenoic acid derivative(I). ##STR1## wherein R is an alkyl, aralkyl or aryl group, R.sup.1 is a hydrogen atom or a carboxy protecting group and Hal is a halogen atom.

Abstract: Plural recesses are formed on the surface of a sheet of a chemically crosslinked foam of a polyolefinic resin containing an inorganic calcium compound, the articles of food to be packaged are placed in the recesses and then the sheet is covered with a physically foamed sheet of a polyolefinic resin containing an inorganic calcium compound. Alternatively, the physically foamed sheet can be shaped to define a recessed support for the food articles and a sheet of foamed polyolefinic resin used as the covering. The polyolefinic resin has 30-60% by weight of an inorganic calcium compound incorporated therein.

Abstract: Lightweight construction materials having a low heat shrinking percentage and a high moisture permeability obtained by forming complementary concavoconvex patterns by means of press molding on both surfaces of a sheet of a foamed polyethylene type resin containing a relatively large amount of inorganic calcic filler, cushion made of said construction materials and mattress manufactured by laminating sheets of soft polyurethane foam on the lightweight construction material as core and covering the whole with cloth.