Patents by Inventor Hiroyuki Kitaoka
Hiroyuki Kitaoka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210128471Abstract: An object of the present invention is to provide a liposome composition containing a liposome having an excellent leakage rate of a nucleic acid analog anticancer agent, and a method for producing the same. According to the present invention, there are provided a liposome composition containing a liposome which (1) contains a nucleic acid analog anticancer agent and in which (2) a content ratio of a lysophospholipid contained in a lipid forming the liposome with respect to a total amount of phospholipids other than the lysophospholipid contained in the lipid forming the liposome is 0.01 mol % to 5 mol % and (3) a nucleic acid analog anticancer agent/lipid ratio is 2 mass % to 10 mass %, and a method for producing the same.Type: ApplicationFiled: January 4, 2021Publication date: May 6, 2021Applicant: FUJIFILM CorporationInventors: Takahiro SEKIGUCHI, Mikinaga MORI, Kentaro NUMAJIRI, Hiroyuki KITAOKA
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Publication number: 20180243215Abstract: An object of the present invention is to provide a liposome composition containing a liposome having an excellent leakage rate of a nucleic acid analog anticancer agent, and a method for producing the same. According to the present invention, there are provided a liposome composition containing a liposome which (1) contains a nucleic acid analog anticancer agent and in which (2) a content ratio of a lysophospholipid contained in a lipid forming the liposome with respect to a total amount of phospholipids other than the lysophospholipid contained in the lipid forming the liposome is 0.01 mol % to 5 mol % and (3) a nucleic acid analog anticancer agent/lipid ratio is 2 mass % to 10 mass %, and a method for producing the same.Type: ApplicationFiled: May 1, 2018Publication date: August 30, 2018Applicant: FUJIFILM CorporationInventors: Takahiro SEKIGUCHI, Mikinaga MORI, Kentaro NUMAJIRI, Hiroyuki KITAOKA
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Patent number: 9993010Abstract: A carotenoid-containing composition including: a carotenoid component containing a crystalline carotenoid that is in an amorphous state; a (poly)glycerol fatty acid ester that contains from one to six glycerol units and from one to six fatty acid units and has at least one hydroxyl group resulting from a glycerol unit; a fatty acid ester component which is at least one selected from the group consisting of triesters of glycerol and fatty acids, and esters of alcohols having one hydroxyl group and fatty acids, contains no hydroxyl group in a molecule, and has from 10 to 60 carbon atoms in total; and an antioxidant.Type: GrantFiled: May 15, 2014Date of Patent: June 12, 2018Assignee: FUJIFILM CorporationInventor: Hiroyuki Kitaoka
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Patent number: 9522110Abstract: A ceramide dispersion composition, includes: at least one ceramide represented by Formula (1) or Formula (2); a surfactant; and trisodium ascorbyl palmitate phosphate, wherein in Formula (1), R1 represents an aliphatic hydrocarbon group having at least one unsaturated double bond, R2 represents an alkyl group having 9 or more carbon atoms, and n represents an integer from 20 to 34; and in Formula (2), R3 represents an aliphatic hydrocarbon group having at least one unsaturated double bond, R4 represents an alkyl group having 9 or more carbon atoms, m represents an integer from 20 to 34, and X represents a hydrogen atom or a hydroxyl group.Type: GrantFiled: August 1, 2016Date of Patent: December 20, 2016Assignee: FUJIFILM CorporationInventors: Terukazu Yanagi, Hiroyuki Kitaoka, Akina Nakaune
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Patent number: 9523182Abstract: A wheel loader is provided with an engine compartment, a urea water injection device, a second side plate, a guiding member, and a suction part. The second side plate has a first outdoor air intake port. The guiding member is configured to guide outdoor air sucked in through the first outdoor air intake port onto the urea water injection device. The suction part sucks air into the engine compartment. The urea water injection device is disposed within an air flow produced between the suction part and the guiding member.Type: GrantFiled: March 31, 2014Date of Patent: December 20, 2016Assignee: KOMATSU LTD.Inventors: Mitsuo Yabe, Akihiro Ohsawa, Toshiya Shintani, Teruyuki Matsuki, Yoshiaki Yoshida, Yosuke Yamagoe, Masahiro Tazou, Hiroyuki Kitaoka
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Publication number: 20160237646Abstract: A wheel loader is provided with an engine compartment, a urea water injection device, a second side plate a guiding member, and a suction part. The second side plate has a first outdoor air intake port. The guiding member is configured to guide outdoor air sucked in through the first outdoor air intake port onto the urea water injection device. The suction part sucks air into the engine compartment. The urea water injection device is disposed within an air flow produced between the suction part and the guiding member.Type: ApplicationFiled: March 31, 2014Publication date: August 18, 2016Inventors: Mitsuo YABE, Akihiro OHSAWA, Toshiya SHINTANI, Teruyuki MATSUKI, Yoshiaki YOSHIDA, Yosuke YAMAGOE, Masahiro TAZOU, Hiroyuki KITAOKA
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Patent number: 9353503Abstract: A wheel loader is provided with an engine compartment, a cooling compartment, a radiator, a cooling fan, a partition wall, a first duct body part, and a top plate. A first end part of the first duct body part is positioned inside the engine compartment. A second end part of the first duct body part is positioned inside the cooling compartment in front of the radiator and the cooling fan. A first outdoor air intake port formed in the top plate is formed in front of the radiator and the cooling fan.Type: GrantFiled: March 31, 2014Date of Patent: May 31, 2016Assignee: KOMATSU LTD.Inventors: Mitsuo Yabe, Akihiro Ohsawa, Toshiya Shintani, Teruyuki Matsuki, Yoshiaki Yoshida, Yosuke Yamagoe, Masahiro Tazou, Hiroyuki Kitaoka
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Publication number: 20150337520Abstract: A wheel loader is provided with an engine compartment, a cooling compartment, a radiator, a cooling fan, a partition wall, a first duct body part, and a top plate. A first end part of the first duct body part is positioned inside the engine compartment. A second end part of the first duct body part is positioned inside the cooling compartment in front of the radiator and the cooling fan. A first outdoor air intake port formed in the top plate is formed in front of the radiator and the cooling fan.Type: ApplicationFiled: March 31, 2014Publication date: November 26, 2015Inventors: Mitsuo YABE, Akihiro OHSAWA, Toshiya SHINTANI, Teruyuki MATSUKI, Yoshiaki YOSHIDA, Yosuke YAMAGOE, Masahiro TAZOU, Hiroyuki KITAOKA
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Patent number: 8966918Abstract: A wheel loader is provided with a cab, an air conditioning unit, a cooling fan which has a condenser and a compressor, an air conditioning switch which receives the operation or non-operation of the compressor, a temperature setting portion which sets a set temperature inside the cab, a room temperature sensor which detects a room temperature inside the cab, and a controller. In a case where the air conditioning switch is operated and the room temperature is higher than a set temperature, the controller maintains the rotation amount of the cooling fan at a limited rotation amount or more.Type: GrantFiled: October 12, 2012Date of Patent: March 3, 2015Assignee: Komatsu Ltd.Inventors: Hiroyuki Kitaoka, Kentaro Yajima
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Publication number: 20140248410Abstract: A carotenoid-containing composition including: a carotenoid component containing a crystalline carotenoid that is in an amorphous state; a (poly)glycerol fatty acid ester that contains from one to six glycerol units and from one to six fatty acid units and has at least one hydroxyl group resulting from a glycerol unit; a fatty acid ester component which is at least one selected from the group consisting of triesters of glycerol and fatty acids, and esters of alcohols having one hydroxyl group and fatty acids, contains no hydroxyl group in a molecule, and has from 10 to 60 carbon atoms in total; and an antioxidant.Type: ApplicationFiled: May 15, 2014Publication date: September 4, 2014Applicant: FUJIFILM CORPORATIONInventor: Hiroyuki KITAOKA
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Patent number: 8800704Abstract: A wheel loader includes a vehicle body frame, an engine, a working unit a fuel tank and a cooling device. The fuel tank is attached to a bottom surface of a rear part of the vehicle body frame, and has a rear end surface slanted obliquely rearwards from up to down. The cooling device is configured to release heat of a coolant flowing through an inside thereof. The cooling device is supported by the rear part of the vehicle body frame. A bottom end portion of the cooling device is opposed to and separated away from a rear end surface of the fuel tank at a predetermined distance in a back-and-forth direction. A bottom surface of the cooling device is positioned lower than a top surface of a rear end portion of the fuel tank.Type: GrantFiled: September 18, 2012Date of Patent: August 12, 2014Assignee: Komatsu Ltd.Inventors: Hiroyuki Kitaoka, Ryuutaro Kato
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Publication number: 20140060099Abstract: A wheel loader is provided with a cab, an air conditioning unit, a cooling fan which has a capacitor and a compressor, an air conditioning switch which receives the operation or non-operation of the compressor, a temperature setting portion which sets a set temperature inside the cab, a room temperature sensor which detects a room temperature inside the cab, and a controller. In a case where the air conditioning switch is operated and the room temperature is higher than a set temperature, the controller maintains the rotation amount of the cooling fan at a limited rotation amount or more.Type: ApplicationFiled: October 12, 2012Publication date: March 6, 2014Inventors: Hiroyuki Kitaoka, Kentaro Yajima
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Publication number: 20140056675Abstract: A wheel loader includes a vehicle body frame, an engine, a working unit a fuel tank and a cooling device. The fuel tank is attached to a bottom surface of a rear part of the vehicle body frame, and has a rear end surface slanted obliquely rearwards from up to down. The cooling device is configured to release heat of a coolant flowing through an inside thereof. The cooling device is supported by the rear part of the vehicle body frame. A bottom end portion of the cooling device is opposed to and separated away from a rear end surface of the fuel tank at a predetermined distance in a back-and-forth direction. A bottom surface of the cooling device is positioned lower than a top surface of a rear end portion of the fuel tank.Type: ApplicationFiled: September 18, 2012Publication date: February 27, 2014Inventors: Hiroyuki Kitaoka, Ryuutaro Kato
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Publication number: 20050272604Abstract: The present invention provides a heat-sensitive recording material in which heat-sensitive recording layers are provided on a support, the heat-sensitive recording layers each containing, as an emulsified dispersion, an electron-accepting compound which reacts with an electron-donating dye precursor to form color, or a coupler compound which reacts with a diazonium salt to form color. At least one layer of the heat-sensitive recording layers contains the emulsified dispersion having a volume average particle size of less than 0.18 ?m. The volume average particle size of the emulsified dispersion is preferably less than 0.5 relative to the volume average particle size of the microcapsules encapsulating the electron-donating dye precursor or the diazonium salt.Type: ApplicationFiled: May 19, 2005Publication date: December 8, 2005Inventors: Toshiyuki Watanabe, Hiroyuki Kitaoka, Tomoki Nakamura, Kazumori Minami