Patents by Inventor Hiroyuki Sonoda

Hiroyuki Sonoda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190225700
    Abstract: Disclosed is a method for production of a fusion protein in which an antibody and a lysosomal enzyme are fused. The method comprises; (a) a step of culturing mammalian cells producing the fusion protein in a serum-free medium to let the mammalian cells secrete the fusion protein in the culture medium, (b) a step of collecting culture supernatant by removing the mammalian cells from the culture medium, and (c) a step of purifying the fusion protein from the culture supernatant by using a column chromatography employing as a solid phase a material to which a substance having affinity for the fusion protein has been bound, a column chromatography employing as a solid phase a material having affinity for the phosphate group, and a size exclusion column chromatography.
    Type: Application
    Filed: August 25, 2017
    Publication date: July 25, 2019
    Applicant: JCR Pharmaceuticals Co., Ltd.
    Inventors: Yuri Koshimura, Hiroyuki Sonoda, Miroslav Matev, Shinji Kakimoto, Tsuyoshi Fukui, Yukichi Hatano
  • Publication number: 20190227630
    Abstract: A main body includes an input component that receives a load. A pressure-sensitive sensor detects the load received by the input component. A drive unit performs a predetermined operation. A drive controller activates the drive unit when the load detected by the pressure-sensitive sensor reaches a predetermined load threshold. A detection controller changes the predetermined load threshold in accordance with the rate of change in the load detected by the pressure-sensitive sensor.
    Type: Application
    Filed: January 16, 2019
    Publication date: July 25, 2019
    Applicant: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LT D.
    Inventors: Kai MASAMOTO, Hiroyuki TOGAWA, Sho SONODA, Shogo MAENAKA, Masaki KITAHASHI
  • Publication number: 20190049088
    Abstract: A light guide is configured to allow at least a portion of light incident on a light-incident surface to be emitted through a peripheral surface. The light guide includes a light guide portion extending in a lengthwise direction of the light guide and formed of a first material and a luminous portion extending in the lengthwise direction of the light guide along the light guide portion and formed of a second material. The second material has a haze value greater than a haze value of the first material.
    Type: Application
    Filed: August 10, 2018
    Publication date: February 14, 2019
    Applicant: KOITO MANUFACTURING CO., LTD.
    Inventors: Asami SAKASHITA, Kazuyuki ISHIKAWA, Hiroaki HARA, Koki MATSUI, Hiroyuki SONODA
  • Publication number: 20180179291
    Abstract: Disclosed is a fusion protein containing a brain-derived neurotrophic factor (BDNF). The fusion protein is a fusion protein of BDNF and a specific range of human anti-transferrin receptor antibody, which makes BDNF administered into the blood able to pass through the blood-brain barrier.
    Type: Application
    Filed: June 24, 2016
    Publication date: June 28, 2018
    Applicant: JCR Pharmaceuticals Co., Ltd.
    Inventors: Hiroyuki Sonoda, Kenichi Takahashi
  • Publication number: 20180171012
    Abstract: Disclosed are a means to convert compounds having physiological or pharmacological activity and unable to pass through the blood-brain barrier into a form that allows them to pass through the blood-brain barrier, and compounds converted thereby. The means is an anti-human transferrin receptor antibody and the converted compounds are molecular conjugates between physiologically active protein or pharmacologically active low-molecular-weight compounds and an anti-human transferrin receptor antibody.
    Type: Application
    Filed: June 24, 2016
    Publication date: June 21, 2018
    Applicant: JCR Pharmaceuticals Co., Ltd.
    Inventors: Hiroyuki Sonoda, Kenichi Takahashi
  • Patent number: 9994641
    Abstract: Disclosed are a novel anti-human transferrin receptor antibody comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 4, 5, 6 and 7 that can pass through the blood-brain barrier, a fusion protein comprising a protein necessary to be brought into function in the central nervous system and the antibody, and method of their production. The fusion protein comprises amino acid sequences of an anti-human transferrin receptor antibody that recognizes an amino acid sequence selected from the group consisting of SEQ ID NOs:1, 2, and 3, and of other protein that is bound thereto on the C-terminal side.
    Type: Grant
    Filed: December 24, 2014
    Date of Patent: June 12, 2018
    Assignee: JCR PHARMACEUTICALS CO., LTD.
    Inventors: Hiroyuki Sonoda, Hideto Morimoto, Yuri Koshimura, Masafumi Kinoshita, Haruna Takagi, Yoshiko Yoshii
  • Publication number: 20170233704
    Abstract: Disclosed is a method for production of recombinant human DNase I which is of such high purity as may be directly used as a medical drug. The method includes the steps of; culturing recombinant DNase I-producing mammalian cells, subjecting a culture supernatant to an anion-exchange column chromatography, subjecting to a column chromatography employing as solid phase a material having affinity for phosphate group, subjecting to a cation-exchange column chromatography, and subjecting to a dye affinity column chromatography.
    Type: Application
    Filed: April 28, 2017
    Publication date: August 17, 2017
    Applicant: JCR PHARMACEUTICALS CO., LTD.
    Inventors: Yuri KOSHIMURA, Miroslav MATEV, Hiroyuki SONODA
  • Publication number: 20160369001
    Abstract: Disclosed are novel anti transferrin receptor antibody that can pass through the blood-brain barrier, a fusion protein comprising a protein necessary to be brought into function in the central nervous system and the antibody, and method of their production. The fusion protein comprises amino acid sequences of an anti-human transferrin receptor antibody that recognizes an amino acid sequence selected from the group consisting of SEQ ID NOs: 1, 2, and 3, and of other protein that is bound thereto on the C- terminal side.
    Type: Application
    Filed: December 24, 2014
    Publication date: December 22, 2016
    Inventors: Hiroyuki SONODA, Hideto MORIMOTO, Yuri KOSHIMURA, Masafumi KINOSHITA, Haruna TAKAGI, Yoshiko YOSHII
  • Patent number: 8685691
    Abstract: Disclosed is an efficient method for production of aminopeptidase. The method comprises either transforming host bacteria with an aminopeptidase gene and with a neutral protease gene, or transforming some part of host bacteria with an aminopeptidase gene while transforming the other part of the host bacteria with a neutral protease gene, culturing in a medium the hose bacteria transformed with the aminopeptidase gene and with the neutral protease gene, or culturing a mixture of the host bacteria transformed with the aminopeptidase gene and the host bacteria transformed with the neutral protease gene, to let both the aminopeptidase and the neutral protease be expressed, and collecting the aminopeptidase thus produced from the culture mixture.
    Type: Grant
    Filed: October 25, 2008
    Date of Patent: April 1, 2014
    Assignee: JCR Pharmaceuticals Co., Ltd.
    Inventors: Hiroyuki Sonoda, Katsuya Daimon, Atsushi Sugimura
  • Publication number: 20120134243
    Abstract: Disclosed is an electronic device in which a transparent member, a decorative plate, and a solar panel are arranged in this order in a metallic device case from an end side of an opening of the device case, wherein the decorative plate has light permeability and has a light refractive part made of a concavo-convex portion on a surface of the decorative plate on the side of the solar panel, and a semi-transmissive reflective plate having both light permeability and light reflectivity is provided between the decorative plate and the solar panel, and the semi-transmissive reflective plate has metal-free vapor deposited film.
    Type: Application
    Filed: November 29, 2011
    Publication date: May 31, 2012
    Applicant: CASIO COMPUTER CO., LTD.
    Inventor: Hiroyuki Sonoda
  • Publication number: 20110027859
    Abstract: Disclosed is an efficient method for production of aminopeptidase. The method comprises either transforming host bacteria with an aminopeptidase gene and with a neutral protease gene, or transforming some part of host bacteria with an aminopeptidase gene while transforming the other part of the host bacteria with a neutral protease gene, culturing in a medium the hose bacteria transformed with the aminopeptidase gene and with the neutral protease gene, or culturing a mixture of the host bacteria transformed with the aminopeptidase gene and the host bacteria transformed with the neutral protease gene, to let both the aminopeptidase and the neutral protease be expressed, and collecting the aminopeptidase thus produced from the culture mixture.
    Type: Application
    Filed: October 25, 2008
    Publication date: February 3, 2011
    Applicant: JCR PHARMACEUTICALS CO., LTD
    Inventors: Hiroyuki Sonoda, Katsuya Daimon
  • Patent number: 7227599
    Abstract: A display device of the invention relates to a display device capable of three-dimensionally representing display on a liquid crystal display element without a hologram. The display device includes a liquid crystal display element and a lens panel. The liquid crystal display element includes a plurality of transparent electrodes on opposed surfaces of a pair of transparent substrates between which a liquid crystal is provided. The lens panel is disposed on the bottom surface side of the liquid crystal display element, and has a plurality of lens portions. The respective lens portions are disposed in regions where the transparent electrodes correspond to each other, and formed in the same shape as that of the respective regions. When displaying information, e.g., a number and a character, on the liquid crystal display element, the information itself can be represented three-dimensionally through the lens portions. Thus, highly decorative display can be obtained.
    Type: Grant
    Filed: June 15, 2004
    Date of Patent: June 5, 2007
    Assignee: Casio Computer Co., Ltd.
    Inventors: Hiroyuki Sonoda, Shingo Ishizaka
  • Patent number: 7064079
    Abstract: A method of removing polymer adhered to a sidewall of an etched metal layer formed on a substrate, includes (a) dissolving the polymer by providing chemicals onto a surface of the substrate, and (b) rinsing the chemicals out of the substrate by providing pure water onto a surface of the substrate, wherein at least a part of the step (a) is carried out in oxidation atmosphere.
    Type: Grant
    Filed: July 10, 2003
    Date of Patent: June 20, 2006
    Assignee: NEC Electronics Corporation
    Inventors: Hiroyuki Sonoda, Hidehiko Kawaguchi, Morimitsu Tanaka, Hiroki Ohno
  • Publication number: 20040257496
    Abstract: A display device of the invention relates to a display device capable of three-dimensionally representing display on a liquid crystal display element without a hologram. The display device includes a liquid crystal display element and a lens panel. The liquid crystal display element includes a plurality of transparent electrodes on opposed surfaces of a pair of transparent substrates between which a liquid crystal is provided. The lens panel is disposed on the bottom surface side of the liquid crystal display element, and has a plurality of lens portions. The respective lens portions are disposed in regions where the transparent electrodes correspond to each other, and formed in the same shape as that of the respective regions. When displaying information, e.g., a number and a character, on the liquid crystal display element, the information itself can be represented three-dimensionally through the lens portions. Thus, highly decorative display can be obtained.
    Type: Application
    Filed: June 15, 2004
    Publication date: December 23, 2004
    Applicant: Casio Computer Co., Ltd.
    Inventors: Hiroyuki Sonoda, Shingo Ishizaka
  • Publication number: 20040009669
    Abstract: A method of removing polymer adhered to a sidewall of an etched metal layer formed on a substrate, includes (a) dissolving the polymer by providing chemicals onto a surface of the substrate, and (b) rinsing the chemicals out of the substrate by providing pure water onto a surface of the substrate, wherein at least a part of the step (a) is carried out in oxidation atmosphere.
    Type: Application
    Filed: July 10, 2003
    Publication date: January 15, 2004
    Applicant: NEC ELECTRONICS CORPORATION
    Inventors: Hiroyuki Sonoda, Hidehiko Kawaguchi, Morimitsu Tanaka, Hiroki Ohno
  • Patent number: 6266297
    Abstract: An analog hand mechanism having hands in a watch case, and a plate-like luminescent device in the watch case, to illuminate the analog hand mechanism. A metallic layer or a metallic ink layer, for giving a feeling of metallic gloss by receiving illumination of light emitted from the surface of the luminescent device, is disposed on at least a side of the upper surface and the lower surface of the luminescent device.
    Type: Grant
    Filed: June 1, 1999
    Date of Patent: July 24, 2001
    Assignee: Casio Computer Co., Ltd.
    Inventors: Hiroyuki Sonoda, Shunji Minami
  • Patent number: 6208591
    Abstract: A translucent or transparent panel member which has a protrusion on the upper surface thereof is disposed on the upper surface of a plate-like luminescent member, to form a luminescent device. The luminescent device is manufactured by forming a protrusion on the upper surface of the panel member, providing a masking layer on the peripheral side surface and the upper surface, of the protrusion, forming a printed layer on the upper surface of the panel member, forming a printed layer on the upper surface of the protrusion after removing the masking layer from the protrusions, and arranging the panel member on the upper surface of the plate-like luminescent member. Such a plate-like luminescent device is arranged in the timepiece case to illuminate the analog hand mechanism. Such a plate-like luminescent device is also arranged in an electronic apparatus case to illuminate a liquid crystal display device of the electronic apparatus.
    Type: Grant
    Filed: September 14, 1998
    Date of Patent: March 27, 2001
    Assignee: Casio Computer Co., Ltd.
    Inventors: Naohiko Sakurazawa, Shunji Minami, Hiroyuki Sonoda
  • Patent number: 6020943
    Abstract: The present invention relates to a display device which is used for various types of electronic apparatuses, e.g., an electronic watch, an electronic pocket notebook, and the like, and an electronic device. In the device or apparatus, a solar battery member having a lot of light passing openings for passing light is provided between a liquid crystal display member and a plate-like light emitting member disposed at a position lower than that of the liquid crystal display member.
    Type: Grant
    Filed: October 19, 1998
    Date of Patent: February 1, 2000
    Assignee: Casio Computer Co., Ltd.
    Inventors: Hiroyuki Sonoda, Norihisa Usui, Shunji Minami, Koji Namiki
  • Patent number: 5930204
    Abstract: The watch and method of manufacture thereof includes an analog hand mechanism having hands in a watch case, and a plate-like luminescent device in the watch case, to illuminate the analog hand mechanism. A metallic layer or a metallic ink layer, for giving a feeling of metallic gloss by receiving illumination of light emitted from the surface of the luminescent device, is disposed on at least a side of the upper surface and the lower surface of the luminescent device.
    Type: Grant
    Filed: August 26, 1998
    Date of Patent: July 27, 1999
    Assignee: Casio Computer Co., Ltd.
    Inventors: Hiroyuki Sonoda, Shunji Minami
  • Patent number: 5880796
    Abstract: The present invention relates to a display device which is used for various types of electronic apparatuses, e.g., an electronic watch, an electronic pocket notebook, and the like, and an electronic device. In the device or apparatus, a solar battery member having a lot of light passing openings for passing light is provided between a liquid crystal display member and a plate-like light emitting member disposed at a position lower than that of the liquid crystal display member.
    Type: Grant
    Filed: July 8, 1997
    Date of Patent: March 9, 1999
    Assignee: Casio Computer Co., Ltd.
    Inventors: Hiroyuki Sonoda, Norihisa Usui, Shunji Minami, Koji Namiki