Patents by Inventor Hisatsugu Yamada

Hisatsugu Yamada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10398788
    Abstract: To provide a polymer having a high ratio of the amount thereof present in a tumor to the amount thereof present in blood (hereinafter, sometimes abbreviated as a tumor/blood ratio). The polymer has phosphorylcholine (derivative) as a side chain and has a dye (near-infrared dye) having absorption in the near-infrared wavelength region bound to the polymer.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: September 3, 2019
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Teruyuki Kondo, Yasuhiro Aoyama, Hisatsugu Yamada, Yoshinori Hasegawa, Shinsuke Sando, Yu Kimura, Natsuki Matsumoto, Fumio Yamauchi, Tetsuya Yano, Masato Minami, Atsushi Takahashi, Kengo Kanazaki, Satoshi Ogawa
  • Patent number: 10029021
    Abstract: As a substance used as a contrast agent for a method of nuclear magnetic resonance analysis or a method of magnetic resonance imaging, a substance with high selectivity and high sensitivity was demanded. According to the present invention, when a polymer having, in a side chain thereof, a sequence of a 1H—13C—15N, 1H—15N—13C or 1H—13C—13C bond, that is, a structure labeled with stable isotopes of 13C and 15N, is used, the abundance of such a sequence in one molecule can be increased, and hence, high selectivity and higher sensitivity can be attained when used as a contrast agent.
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: July 24, 2018
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Teruyuki Kondo, Yasuhiro Aoyama, Hisatsugu Yamada, Yoshinori Hasegawa, Hidehito Tochio, Yu Kimura, Masahiro Shirakawa, Fuminori Sugihara, Tetsuya Matsuda, Shinsuke Sando, Masato Minami, Fumio Yamauchi, Tetsuya Yano, Hidetoshi Tsuzuki
  • Publication number: 20170333575
    Abstract: To provide a polymer having a high ratio of the amount thereof present in a tumor to the amount thereof present in blood (hereinafter, sometimes abbreviated as a tumor/blood ratio). The polymer has phosphorylcholine (derivative) as a side chain and has a dye (near-infrared dye) having absorption in the near-infrared wavelength region bound to the polymer.
    Type: Application
    Filed: October 9, 2015
    Publication date: November 23, 2017
    Inventors: Teruyuki Kondo, Yasuhiro Aoyama, Hisatsugu Yamada, Yoshinori Hasegawa, Shinsuke Sando, Yu Kimura, Natsuki Matsumoto, Fumio Yamauchi, Tetsuya Yano, Masato Minami, Atsushi Takahashi, Kengo Kanazaki, Satoshi Ogawa
  • Publication number: 20150071861
    Abstract: As a substance used as a contrast agent for a method of nuclear magnetic resonance analysis or a method of magnetic resonance imaging, a substance with high selectivity and high sensitivity was demanded. According to the present invention, when a polymer having, in a side chain thereof, a sequence of a 1H—13C—15N, 1H—15N—13C or 1H—13C—13C bond, that is, a structure labeled with stable isotopes of 13C and 15N, is used, the abundance of such a sequence in one molecule can be increased, and hence, high selectivity and higher sensitivity can be attained when used as a contrast agent.
    Type: Application
    Filed: May 22, 2013
    Publication date: March 12, 2015
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Teruyuki Kondo, Yasuhiro Aoyama, Hisatsugu Yamada, Yoshinori Hasegawa, Hidehito Tochio, Yu Kimura, Masahiro Shirakawa, Fuminori Sugihara, Tetsuya Matsuda, Shinsuke Sando, Masato Minami, Fumio Yamauchi, Tetsuya Yano, Hidetoshi Tsuzuki