Patents by Inventor Hitoshi Fukushima

Hitoshi Fukushima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170283791
    Abstract: A nucleic acid-binding solid-phase carrier includes a magnetic particle of an amorphous metal containing Fe, Cr, Si, and B, and a silicon oxide film provided on the surface of the magnetic particle.
    Type: Application
    Filed: March 29, 2017
    Publication date: October 5, 2017
    Applicant: Seiko Epson Corporation
    Inventors: Hitoshi FUKUSHIMA, Yuji SAITO, Fumio TAKAGI, Atsushi WATANABE, Yu MAEDA
  • Patent number: 9506933
    Abstract: The object of the present invention is to provide a method to obtain an antibody for a hydrophobic peptide, which can be used for general purposes easily and with great reliability. Also provided is a method for preparing an antigen characterized in that a hydrophobic peptide, which is unbound to carrier protein, is used as high-molecular-weight aggregates in an aqueous solution containing a nonionic surfactant.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: November 29, 2016
    Assignees: TOAGOSEI CO., LTD., SEIKO EPSON CORPORATION
    Inventors: Masaji Okamoto, Masato Hanamura, Hitoshi Fukushima, Tetsuhiko Yoshida
  • Patent number: 9309307
    Abstract: An advantage of some aspects of the invention is to provide an antibody against an amyloid precursor protein signal peptide. The invention provides an amyloid precursor protein signal peptide.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: April 12, 2016
    Assignees: SEIKO EPSON CORPORATION, TOAGOSEI CO., LTD.
    Inventors: Hitoshi Fukushima, Masato Hanamura, Mikio Niwa, Masaji Okamoto, Tomoko Naoe, Tetsuhiko Yoshida
  • Patent number: 9068979
    Abstract: A micro bio sensor which detects a microbe existing in a specimen is provided. The microbial sensor includes a base, a detector formed on the base, and a reaction layer formed on the detector, wherein the reaction layer is comprised of a self-assembled monolayer which is formed on the detector and an antibiotic which is immobilized through the self-assembled monolayer on the detector. By using the micro bio sensor, it is possible to detect species of the microbe concurrently and improve sensitivity for detecting the species of the microbe. Further, a method for manufacturing such a micro bio sensor is also provided.
    Type: Grant
    Filed: May 20, 2008
    Date of Patent: June 30, 2015
    Assignee: Seiko Epson Corporation
    Inventors: Hitoshi Fukushima, Akira Nishimura, Mitsuhiro Ban, Asahi Yamazaki, Takuya Asai
  • Publication number: 20140072592
    Abstract: The object of the present invention is to provide a method to obtain an antibody for a hydrophobic peptide, which can be used for general purposes easily and with great reliability. Also provided is a method for preparing an antigen characterized in that a hydrophobic peptide, which is unbound to carrier protein, is used as high-molecular-weight aggregates in an aqueous solution containing a nonionic surfactant.
    Type: Application
    Filed: January 6, 2012
    Publication date: March 13, 2014
    Applicants: SEIKO EPSON CORPORATION, TOAGOSEI CO., LTD.
    Inventors: Masaji Okamoto, Masato Hanamura, Hitoshi Fukushima, Tetsuhiko Yoshida
  • Publication number: 20130345408
    Abstract: An advantage of some aspects of the invention is to provide an antibody against an amyloid precursor protein signal peptide. The invention provides an amyloid precursor protein signal peptide.
    Type: Application
    Filed: January 6, 2012
    Publication date: December 26, 2013
    Applicants: TOAGOSEI CO. LTD., SEIKO EPSON CORPORATION
    Inventors: Hitoshi Fukushima, Masato Hanamura, Mikio Niwa, Masaji Okamoto, Tomoko Naoe, Tetsuhiko Yoshida
  • Patent number: 8445285
    Abstract: A liquid for ejection includes a bio-specimen, and at least one kind of first compounds expressed by Formula (1), wherein, in Formula (1), m?8, and 8?n?18.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: May 21, 2013
    Assignee: Seiko Epson Corporation
    Inventors: Hitoshi Fukushima, Yukihiro Hanaoka
  • Patent number: 8354278
    Abstract: A liquid for discharge includes: a biospecimen; and at least one kind of compounds represented by the formula (1). In the formula (1), m?8, and 6?n?20.
    Type: Grant
    Filed: January 7, 2011
    Date of Patent: January 15, 2013
    Assignee: Seiko Epson Corporation
    Inventors: Hitoshi Fukushima, Yukihiro Hanaoka
  • Patent number: 8343333
    Abstract: An electrode substrate including an electrode and a membrane provided on the electrode and having a thickness with which a carrier is exchanged between the electrode and the membrane.
    Type: Grant
    Filed: February 24, 2006
    Date of Patent: January 1, 2013
    Assignee: Seiko Epson Corporation
    Inventors: Hitoshi Fukushima, Hiroshi Takiguchi
  • Patent number: 8217857
    Abstract: A display, comprising: a planar display section; a pixel space provided next to a side adjacent to one surface of the display section and encapsulating a plurality of kinds of colorants, each kind having a different color; an accumulation section provided in the pixel space and accumulating the colorants; a separation system that separates a specific kind of colorant from the accumulated colorants in the accumulation section; a transfer system that selects at least one kind of colorant from the separated colorants and transfers this colorant to the side adjacent to the display section of the pixel space. The separation system performs separation utilizing the magnitude of a dielectrophoretic force generated in each colorant upon receipt of an alternating electric field of a specific frequency applied by this system, the magnitude varying depending on the kind of the colorant. A color of at least the one kind of colorant transferred by the transfer system is displayed at the display section.
    Type: Grant
    Filed: March 6, 2008
    Date of Patent: July 10, 2012
    Assignee: Seiko Epson Corporation
    Inventors: Takeo Kawase, Takayuki Kondo, Hitoshi Fukushima, Yuji Shinohara
  • Patent number: 7998413
    Abstract: Aspects of the invention can be an inexpensive biosensor capable of measuring a number of samples in a short time, and suitable for only one-time use (expendable). The biosensor according to the invention can include a light transmissive substrate, a probe fixing region provided on one face of the light transmissive substrate, a light emitting element provided on the other face of the substrate that irradiates the probe fixing region from the back side thereof, and a light receiving element provided on the other face of the substrate that detects the light intensity of the reflected light from the back side of the probe fixing region. Thereby, a biosensor formed in one substrate can be obtained.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: August 16, 2011
    Assignee: Seiko Epson Corporation
    Inventors: Hitoshi Fukushima, Takayuki Kondo
  • Publication number: 20110177490
    Abstract: A liquid for discharge includes: a biospecimen; and at least one kind of compounds represented by the formula (1). In the formula (1), m?8, and 6?n?20.
    Type: Application
    Filed: January 7, 2011
    Publication date: July 21, 2011
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Hitoshi FUKUSHIMA, Yukihiro HANAOKA
  • Patent number: 7955705
    Abstract: An electronic device substrate includes a substrate having at least one of a metal and a metal oxide on a surface thereof and an underlying layer having a compound expressed by a following general formula (1): wherein X presents one of a hydrogen atom and a protecting group; Y1 represents one of an oxygen atom, an alkylene group and —N(R1)—, in which R1 represents an alkyl group; Z1 represents a polymerization initiating group; n1 represents an integer from 1 to 4; and m1 represents an integer from 1 to 15.
    Type: Grant
    Filed: April 25, 2007
    Date of Patent: June 7, 2011
    Assignee: Seiko Epson Corporation
    Inventors: Hitoshi Fukushima, Shinobu Yokokawa
  • Publication number: 20100327008
    Abstract: A liquid for ejection includes a bio-specimen, and at least one kind of first compounds expressed by Formula (1), wherein, in Formula (1), m?8, and 8?n?18.
    Type: Application
    Filed: June 25, 2010
    Publication date: December 30, 2010
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Hitoshi FUKUSHIMA, Yukihiro Hanaoka
  • Patent number: 7833396
    Abstract: A biochip, includes: an ink-jet head portion detachably mountable to a biosensor; a sensing electrode formed with a work electrode, a reference electrode, and a counter electrode; and a thin film transistor.
    Type: Grant
    Filed: December 28, 2006
    Date of Patent: November 16, 2010
    Assignee: Seiko Epson Corporation
    Inventor: Hitoshi Fukushima
  • Publication number: 20100264024
    Abstract: A biochip, includes: an ink-jet head portion detachably mountable to a biosensor; a sensing electrode formed with a work electrode, a reference electrode, and a counter electrode; and a thin film transistor.
    Type: Application
    Filed: December 28, 2006
    Publication date: October 21, 2010
    Applicant: SEIKO EPSON CORPORATION
    Inventor: Hitoshi FUKUSHIMA
  • Patent number: 7524998
    Abstract: A dendron (2) comprising a focal point (4) and a plurality of fluorinated end groups (9) is disclosed, including one having a thiol, a silane, a carboxylic acid, a phosphonate or another moiety at the focal point suitable for chemisorption to a substrate (3). A self-assembled monolayer comprising a plurality of dendrons bonded to a substrate and a device comprising the self-assembled monolayer are also disclosed.
    Type: Grant
    Filed: June 30, 2005
    Date of Patent: April 28, 2009
    Assignees: Seiko Epson Corporation, Cambridge University Technical Service, Ltd.
    Inventors: Hitoshi Fukushima, Satoshi Nebashi, Masaya Ishida, Wilhelm J S Huck, Andrew B Holmes, Christine K Luscombe
  • Publication number: 20090081766
    Abstract: A micro bio sensor which detects a microbe existing in a specimen is provided. The microbial sensor includes a base, a detector formed on the base, and a reaction layer formed on the detector, wherein the reaction layer is comprised of a self-assembled monolayer which is formed on the detector and an antibiotic which is immobilized through the self-assembled monolayer on the detector. By using the micro bio sensor, it is possible to detect species of the microbe concurrently and improve sensitivity for detecting the species of the microbe. Further, a method for manufacturing such a micro bio sensor is also provided.
    Type: Application
    Filed: May 20, 2008
    Publication date: March 26, 2009
    Applicants: Seiko Epson Corporation, HAKUTSURU SAKE BREWING CO., LTD.
    Inventors: Hitoshi FUKUSHIMA, Akira Nishimura, Mitsuhiro Ban, Asahi Yamazaki, Takuya Asai
  • Patent number: 7491496
    Abstract: A method is provided to enable high-density absorption when immobilizing nucleic acid probes onto a solid support surface by suppressing electrostatic repulsion among the nucleic acids. A nucleic acid immobilization method to immobilize a nucleic acid onto a solid support, includes: preparing a solution containing a probe molecule which includes a nucleic acid, a spacer molecule, and at least one kind of a divalent cation; and contacting the solution with the solid support for incubation.
    Type: Grant
    Filed: March 28, 2005
    Date of Patent: February 17, 2009
    Assignee: Seiko Epson Corporation
    Inventors: Hiroshi Takiguchi, Hitoshi Fukushima
  • Patent number: 7479362
    Abstract: Aspects of the invention provide a method of controlling the solid-state property of the solid-phase surface or controlling forming reactive region. The method can be attained by using a device for ejecting droplets and a molecule for inclusion in a SAM which can be photo-patterned in a short period of time using low energy UV radiation, that is TV radiation having a relatively long wavelength. The invention can provide monomolecular film that is formed from molecules comprising a structural component (B) which is hydrophobic and/or lipophobic, and a structural component (A) which decomposes when irradiated with UV light having a wavelength in the range 254-400 nm to cleave away a part of the molecule having the structural component (B) leaving a residual hydrophilic structural component (C).
    Type: Grant
    Filed: April 28, 2005
    Date of Patent: January 20, 2009
    Assignee: Seiko Epson Corporation
    Inventors: Hitoshi Fukushima, Hiroshi Takiguchi, Tatsuya Shimoda, Takashi Masuda, Richard James Bushby, Stephan Evans, J.P. Jeyadevan, Kevin Critchley