Patents by Inventor Hitoshi Mitsuzumi

Hitoshi Mitsuzumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230293416
    Abstract: The object of the present invention is to provide a stabilizer for and a method for stabilizing an emulsion composition emulsified with a non-ionic surfactant. This invention solves the above object by providing a stabilizer for an emulsion composition emulsified with a non-ionic surfactant; the stabilizer comprising a glycosyl naringenin as an effective ingredient, and a method for stabilizing an emulsion composition emulsified with a non-ionic surfactant; the method comprising a step of having a stabilizer that comprises a glycosyl naringenin as an active ingredient mixed and/or contained in a starting material of the emulsion composition, an intermediate product of the emulsion composition, and/or the emulsion composition manufactured.
    Type: Application
    Filed: February 16, 2021
    Publication date: September 21, 2023
    Inventors: Miho HANAOKA, Masahiro OTAO, Masaki MIYAKE, Hitoshi MITSUZUMI
  • Publication number: 20230242957
    Abstract: The present invention aims to provide a saccharide composition suitable for a cyclic-tetrasaccharide-containing starch syrup which has low viscosity, low water activity, low coloration property, and low calorie content, and which is unlikely to cause precipitation of crystals of saccharides during storage, and to provide a use of the composition and a production method for the composition.
    Type: Application
    Filed: October 2, 2020
    Publication date: August 3, 2023
    Inventors: Akiko YASUDA, Manabu MIYATA, Takuo YAMAMOTO, Akiko MIZOTE, Hitoshi MITSUZUMI
  • Patent number: 11453694
    Abstract: The present invention aims to provide a novel glycosyl hesperetin, which is significantly reduced in miscellaneous tastes characteristic of conventional products containing glycosyl hesperetin, and a method for producing the same and uses thereof; and the objects are solved by providing a glycosyl hesperetin which comprises glycosyl hesperetin in an amount of 90% or more by mass but less than 100% by mass, on a dry solid basis, but it does not substantially contain furfural, and a method for producing the same and uses thereof.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: September 27, 2022
    Assignee: HAYASHIBARA CO. LTD.
    Inventors: Mitsuyuki Kambe, Koichi Nishi, Akira Kawashima, Akiko Yasuda, Hitoshi Mitsuzumi, Toshio Ariyasu
  • Publication number: 20220202685
    Abstract: The present invention addresses the problem of providing a gel-type skin external composition containing a L-ascorbic acid derivative, which has excellent shape retention, stability, and excellent feeling of use even when salts coexist in the composition. The above problem is solved by providing a gel-type skin external composition containing a L-ascorbic acid derivative, a nonionic synthetic water-soluble polymer, and a natural water-soluble polysaccharide.
    Type: Application
    Filed: May 1, 2020
    Publication date: June 30, 2022
    Inventors: Kiyomi AIZAWA, Masaki MIYAKE, Hitoshi MITSUZUMI
  • Publication number: 20220062318
    Abstract: The present invention addresses the problem of providing a novel heat stress relieving agent that can be taken easily, conveniently and safely even by infants and the elderly, who are susceptible to heat stress such as heat illness, that rapidly promotes sweating in a heat stress environment, and that prevents, alleviates, or improves symptoms and disorders caused by heat stress, such as heat illness. The above problem is solved by providing a heat stress relieving agent containing glycosyl hesperetin as an effective ingredient, and a basal body temperature maintaining agent containing glycosyl hesperetin as an effective ingredient.
    Type: Application
    Filed: December 24, 2019
    Publication date: March 3, 2022
    Inventors: Satoko HASHIMOTO, Chiyo YOSHIZANE, Saori OGIHARA, Shin ENDO, Masaki MIYAKE, Hitoshi MITSUZUMI
  • Publication number: 20200283466
    Abstract: The present invention aims to provide a novel glycosyl hesperetin, which is significantly reduced in miscellaneous tastes characteristic of conventional products containing glycosyl hesperetin, and a method for producing the same and uses thereof; and the objects are solved by providing a glycosyl hesperetin which comprises glycosyl hesperetin in an amount of 90% or more by mass but less than 100% by mass, on a dry solid basis, but it does not substantially contain furfural, and a method for producing the same and uses thereof.
    Type: Application
    Filed: May 20, 2020
    Publication date: September 10, 2020
    Inventors: Mitsuyuki KAMBE, Koichi NISHI, Akira KAWASHIMA, Akiko YASUDA, Hitoshi MITSUZUMI, Toshio ARIYASU
  • Patent number: 10703773
    Abstract: The present invention aims to provide a novel glycosyl hesperetin, which is significantly reduced in miscellaneous tastes characteristic of conventional products containing glycosyl hesperetin, and a method for producing the same and uses thereof; and the objects are solved by providing a glycosyl hesperetin which comprises glycosyl hesperetin in an amount of 90% or more by mass but less than 100% by mass, on a dry solid basis, but it does not substantially contain furfural, and a method for producing the same and uses thereof.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: July 7, 2020
    Assignee: HAYASHIBARA CO. LTD.
    Inventors: Mitsuyuki Kambe, Koichi Nishi, Akira Kawashima, Akiko Yasuda, Hitoshi Mitsuzumi, Toshio Ariyasu
  • Publication number: 20170081354
    Abstract: The present invention aims to provide a novel glycosyl hesperetin, which is significantly reduced in miscellaneous tastes characteristic of conventional products containing glycosyl hesperetin, and a method for producing the same and uses thereof; and the objects are solved by providing a glycosyl hesperetin which comprises glycosyl hesperetin in an amount of 90% or more by mass but less than 100% by mass, on a dry solid basis, but it does not substantially contain furfural, and a method for producing the same and uses thereof.
    Type: Application
    Filed: March 3, 2015
    Publication date: March 23, 2017
    Inventors: Mitsuyuki KAMBE, Koichi NISHI, Akira KAWASHIMA, Akiko YASUDA, Hitoshi MITSUZUMI, Toshio ARIYASU
  • Publication number: 20100210589
    Abstract: An object of the present invention is to provide a means for improving hepatic function of mammals including humans to normal condition. The present invention achieves the above object by providing a hepatic function-improving agent comprising ?-glucosyl-hesperidin as an effective ingredient.
    Type: Application
    Filed: April 27, 2010
    Publication date: August 19, 2010
    Applicant: Kabushiki Kaisha Kayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Hitoshi MITSUZUMI, Mika TAKAMI, Yoshikatsu MIWA, Hiroto CHAEN, Toshio MIYAKE
  • Publication number: 20080221045
    Abstract: An object of the present invention is to provide a means for improving hepatic function of mammals including humans to normal condition. The present invention achieves the above object by providing a hepatic function-improving agent comprising ?-glucosyl-hesperidin as an effective ingredient.
    Type: Application
    Filed: November 21, 2005
    Publication date: September 11, 2008
    Applicant: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Hitoshi Mitsuzumi, Mika Takami, Yoshikatsu Miwa, Hiroto Chaen, Toshio Miyake
  • Patent number: 6346394
    Abstract: Disclosed is a recombinant thermostable enzyme which has a molecular weight of about 54,000-64,000 daltons and a pI of about 5.6-6.6, and releases trehalose from non-reducing saccharides having a trehalose structure as an end unit and a degree of glucose polymerization of at least 3. The enzyme has a satisfactorily-high thermostability, i.e. it is not substantially inactivated even when incubated in an aqueous solution (pH 7.0) at 85° C. for 60 min, and this facilitates the production of trehalose on an industrial scale and in a satisfactorily-high yield.
    Type: Grant
    Filed: April 6, 1998
    Date of Patent: February 12, 2002
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Hitoshi Mitsuzumi, Michio Kubota, Toshiyuki Sugimoto
  • Patent number: 6027918
    Abstract: Disclosed is a recombinant thermostable enzyme which has a molecular weight of about 54,000-64,000 daltons and a pI of about 5.6-6.6, and releases trehalose from non-reducing saccharides having a trehalose structure as an end unit and a degree of glucose polymerization of at least 3. The enzyme has a satisfactorily-high thermostability, i.e. it is not substantially inactivated even when incubated in an aqueous solution (pH 7.0) at 85.degree. C. for 60 min, and this facilitates the production of trehalose on an industrial scale and in a satisfactorily-high yield.
    Type: Grant
    Filed: February 11, 1997
    Date of Patent: February 22, 2000
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Hitoshi Mitsuzumi, Michio Kubota, Toshiyuki Sugimoto
  • Patent number: 5856146
    Abstract: Disclosed is a recombinant thermostable enzyme which has a molecular weight of about 54,000-64,000 daltons and a pI of about 5.6-6.6, and releases trehalose from non-reducing saccharides having a trehalose structure as an end unit and a degree of glucose polymerization of at least 3. The enzyme has a satisfactorily-high thermostability, i.e. it is not substantially inactivated even when incubated in an aqueous solution (pH 7.0) at 85.degree. C. for 60 min, and this facilitates the production of trehalose on an industial scale and in a satisfactorily-high yield.
    Type: Grant
    Filed: July 21, 1995
    Date of Patent: January 5, 1999
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Hitoshi Mitsuzumi, Michio Kubota, Toshiyuki Sugimoto