Patents by Inventor Hong Liu

Hong Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11873292
    Abstract: The present invention relates to the fields of medicinal chemistry and pharmacotherapy, and specifically relates to the chemical compound of formula (I), and its racemate, R-isomer, S-isomer, pharmaceutically acceptable salt, and mixtures thereof, as well as its method for preparation, a pharmaceutical composition containing said chemical compound, and use as a lysine-specific demethylase 1 (LSD 1) inhibitor. The cyclopropylamine chemical compound to which the present invention relates may be used in the treatment of cancer.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: January 16, 2024
    Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    Inventors: Hong Liu, Jia Li, Wei Zhu, Yubo Zhou, Jiang Wang, Mingbo Su, Shuni Wang, Wei Xu, Chunpu Li, Weijuan Kan, Hualiang Jiang, Kaixian Chen
  • Patent number: 11863065
    Abstract: A method for controlling a power module includes: configuring N cells in cascade connection, where N is a positive integer equal to or greater than 2, each cell comprising a bidirectional switching unit and a non-controlled rectifier bridge, the bidirectional switching unit being connected to central points of two bridge arms of the non-controlled rectifier bridge; controlling each cell to operate in one of three operating modes of a modulation mode, a bypass mode and a non-controlled rectifying mode, wherein in the N cells, m1 cells operate in the bypass mode, where 0?m1?M1, m2 cells operate in the non-controlled rectifying mode, where 0?m2?M2, m3 cells operate in the modulation mode and can realize power factor correction, where 0<m3; wherein m1+m2+m3=N, M1 is the allowable number of cells for bypass in the system, and M2 is the allowable number of cells for non-controlled rectification in the system.
    Type: Grant
    Filed: April 11, 2022
    Date of Patent: January 2, 2024
    Assignee: DELTA ELECTRONICS (SHANGHAI) CO., LTD.
    Inventors: Hong Liu, Wen Zhang, Dan Wang, Cheng Lu, Hongyang Wu
  • Patent number: 11845672
    Abstract: Disclosed are an alumina-based heterojunction material with abundant oxygen vacancies and a preparation method thereof. The heterojunction material is composed of alumina with abundant oxygen vacancies and bismuth-rich bismuth oxychloride. The method includes mixing aluminum nitrate nonahydrate, bismuth nitrate pentahydrate, an ammonium salt and urea, each in certain amount, under stirring to obtain a mixture B, placing the mixture B in a muffle furnace, heating the mixture B and continuing the stirring to gradually melt the mixture B to form an ionic liquid B; and subjecting the ionic liquid B to a spontaneous combustion reaction in the muffle furnace to obtain a product B, and cooling the product B to room temperature to obtain the alumina-based heterojunction material with abundant oxygen vacancies.
    Type: Grant
    Filed: July 15, 2022
    Date of Patent: December 19, 2023
    Assignee: HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Fa-tang Li, Qi Li, Shao-qiang Li, Ying Liu, Rui-hong Liu
  • Publication number: 20230400726
    Abstract: A display panel, a display module and a display device, and relates to the field of display technology and includes: a first base substrate and a second base substrate arranged oppositely; a liquid crystal layer and a plurality of conductive layers, wherein the liquid crystal layer and the plurality of conductive layers are located between the first base substrate and the second base substrate; and a plurality of heating elements, wherein the plurality of heating elements are distributed in at least one of the conductive layers.
    Type: Application
    Filed: May 11, 2022
    Publication date: December 14, 2023
    Inventors: Jianyun XIE, Peng LIU, Jingyi XU, Hong LIU, Peirong HUO, Zhiming LI, Guodong WANG
  • Publication number: 20230386737
    Abstract: A compensation structure for reducing circulating current in a window of a transformer, the transformer having a winding, a metal frame and leads located at one side of the frame and spaced apart from the frame. The frame has borders and an iron core located inside a window enclosed by the borders. The winding is provided around the iron core, wherein the compensation structure includes at least one compensator on the borders of the frame. The compensator is made of silicon steel sheets of a magnetic material, and the compensator separates at least a part of the borders of the frame from a part of the leads. The compensation structure separates iron structures between a high-voltage side and a low-voltage side, increases the impedance between the window circuit of the frame and the current circuit of external leads, thereby reducing the induced current within the frame and avoiding harmful effects.
    Type: Application
    Filed: October 26, 2020
    Publication date: November 30, 2023
    Applicant: Siemens Energy Global GmbH & Co. KG
    Inventors: Lin Da Li, Egon Kirchenmayer, Zhu Sheng Chi, Hong Liu
  • Patent number: 11827672
    Abstract: Described herein are antibodies (e.g., single chain variable fragment (scFv) antibodies) and constructs comprising antibody moieties that bind to the extracellular domain of CD22 or a portion thereof (e.g., SEQ ID NO: 205 or a portion thereof). Also provided herein are methods of using the same or compositions thereof for the therapeutic treatment of diseases characterized by CD22 expression, in particular, B-cell lymphomas and leukemias.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: November 28, 2023
    Assignee: Eureka Therapeutics, Inc.
    Inventors: Jun Cui, Pengbo Zhang, Yiyang Xu, Shan Li, Yixiang Xu, Guangyan Xiong, Hongruo Yun, Lianxing Liu, Xiaomei Ge, Shaohua Xu, Hong Liu, Javier Morales
  • Patent number: 11823795
    Abstract: A calling device of a MRI system may include a reader/writer and a call maker. The reader/writer can send a fixed-frequency electromagnetic wave. The call maker may include a main body, an antenna, an operating member, and an answering controller. The antenna can generate an induced current after receiving the fixed-frequency electromagnetic wave. The operating member can switch between first and second positions relative to the main body. The answering controller is configured such that: when the operating member is in the first position, a first radio-frequency signal is sent through the antenna with energy obtained from the induced current generated by the antenna, and when the operating member is in the second position, a second radio-frequency signal is sent through the antenna with energy obtained from the induced current generated by the antenna. The reader/writer can send different prompt signals according to the first and second radio-frequency signals.
    Type: Grant
    Filed: November 24, 2021
    Date of Patent: November 21, 2023
    Assignee: Siemens Healthcare GmbH
    Inventors: Ting Qiang Xue, JianMin Wang, Jian Hong Liu
  • Patent number: 11813073
    Abstract: A wound multiple sensing method, including: calculating the similarity between the current data sequence and each of the case-data sequences in each of the reference cases; selecting the case-data sequence which has the greatest similarity with the current data sequence, from the case-data sequences in each of the reference cases, to be a similar case-data sequence in each of the reference cases, wherein each similar case-data sequence corresponds to a similar case treatment; performing a multiple regression analysis using the similar case-data sequences and the similar case treatments to calculate a fitness function, wherein the dependent variable of the fitness function is a wound change; performing a parameter optimization algorithm using the current data sequence and the fitness function to calculate an optimal treatment which maximizes the wound change, and to calculate an expected wound change value that corresponds to the optimal treatment.
    Type: Grant
    Filed: December 23, 2020
    Date of Patent: November 14, 2023
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yue-Min Jiang, Jian-Hong Liu, Shang-Chih Hung, Ho-Hsin Lee, Jian-Ren Chen, Min-Yi Hsieh, Ren-Guey Lee
  • Patent number: 11812738
    Abstract: This invention provides polynucleotide molecules and methods for regulating genes in plants, e. g., by providing RNA for systemic regulation of genes. Various aspects of the invention provide polynucleotide molecules and methods for regulating endogenous genes and transgenes in a plant cell and polynucleotide molecules.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: November 14, 2023
    Assignee: Monsanto Technology LLC
    Inventors: Robert D Sammons, Sergey Ivashuta, Hong Liu, Dafu Wang, Paul C. C. Feng, Andrei Y Kouranov, Scott E Andersen
  • Publication number: 20230360977
    Abstract: A method includes: transferring a wafer from a factory interface through a load lock chamber to a buffer chamber; transferring the wafer from the buffer chamber to a process chamber; etching the wafer in the process chamber, to remove a material of the wafer; and after the wafer is etched, performing reflectance measurements to the wafer in the factory interface, the load lock chamber, the buffer chamber, or combination thereof, to identify if the material of the wafer is removed entirely according to a reflectance of the wafer.
    Type: Application
    Filed: July 20, 2023
    Publication date: November 9, 2023
    Applicant: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.
    Inventors: Yan-Hong LIU, Daniel M.Y. YANG, Che-Fu CHEN
  • Publication number: 20230355213
    Abstract: An ultrasound image processing apparatus includes an image processor arrangement that receives a plurality of ultrasound images. Each ultrasound image shows an invasive medical device relative to an anatomical feature during a cardiac cycle. At different phases of the cardiac cycle, the anatomical feature has a different shape. The ultrasound processing apparatus compiles groups of the ultrasound images with ultrasound images in each group belonging to the same phase of the cardiac cycle. The ultrasound image processing apparatus generates an augmented ultrasound image from one of the ultrasound images by removing a shadow region on the anatomical feature of interest caused by the invasive medical device based on a displacement of the invasive medical device.
    Type: Application
    Filed: July 7, 2023
    Publication date: November 9, 2023
    Inventors: Alexander Franciscus Kolen, Harm Jan Willem Belt, Godefridus Antonius Harks, Geert Gerardus Henricus Maria Gijsbers, Hong Liu
  • Patent number: 11811310
    Abstract: Embodiments of the present disclosure provide a power conversion system and a control method. The power conversion system includes multiple power modules, and each power module includes a first port, a second port, and a third port, where the first port of each power module is connected to an external device, second ports of the power modules are independent of each other and used as independent ports to output power, third ports of the power modules are connected in parallel to form a power bus and power flow of the third port of each power module is bidirectional.
    Type: Grant
    Filed: September 8, 2021
    Date of Patent: November 7, 2023
    Assignee: Delta Electronics (Shanghai) Co., Ltd.
    Inventors: Cheng Lu, Hong Liu, Wenfei Hu, Jie Kong
  • Patent number: 11811297
    Abstract: A power module includes N inverter units outputting N AC voltages and being coupled to N high-frequency AC terminals, wherein the N high-frequency AC terminals are cascaded and connected to a post-stage rectifier circuit. A phase-shift control method for the power module includes: setting at least two phase-shift sequences, wherein phase sequence numbers of the N AC voltages of the N inverter units are different in the at least two phase-shift sequences; in one switching period, controlling the N AC voltages of the N inverter units to shift a first angle according to a first phase-shift sequence of the at least two phase-shift sequences; and in another switching period, controlling the N AC voltages of the N inverter units to shift the first angle according to a second phase-shift sequence of the at least two phase-shift sequences.
    Type: Grant
    Filed: April 11, 2022
    Date of Patent: November 7, 2023
    Assignee: DELTA ELECTRONICS (SHANGHAI) CO., LTD.
    Inventors: Hong Liu, Jie Kong, Wen Zhang, Baihui Song, Cheng Lu, Hongyang Wu
  • Publication number: 20230350255
    Abstract: The present disclosure provides a display substrate and a display panel, and belongs to the field of display technology. The present display substrate includes a display region and a peripheral region surrounding the display region; the display substrate includes: a base substrate; a plurality of insulating layers sequentially arranged along a direction away from the base substrate; wherein each of the plurality of insulating layers is located in the display region and the peripheral region; one or more protrusion structures arranged between at least two adjacent ones of the plurality of insulating layers and in the peripheral region.
    Type: Application
    Filed: August 18, 2021
    Publication date: November 2, 2023
    Inventors: Hong LIU, Jingyi XU, Xiaochun XU, Jiantao LIU, Wanzhi CHEN, Chengfu XU, Bo LI, Yongqiang ZHANG, Peng LIU, Ruirui HAO, Yu FENG, Xinguo WU
  • Patent number: 11802122
    Abstract: Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are inhibitors of Nav1.8 channel activity and may be useful in the treatment, prevention, management, amelioration, control and suppression of diseases mediated by Nav1.8 channel activity. The compounds of the present invention may be useful in the treatment, prevention or management of pain disorders, cough disorders, acute itch disorders, and chronic itch disorders.
    Type: Grant
    Filed: June 15, 2021
    Date of Patent: October 31, 2023
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Ashok Arasappan, Ian M. Bell, Christopher James Bungard, Christopher S. Burgey, Jason M. Cox, Michael J. Kelly, III, Mark E. Layton, Hong Liu, Jian Liu, James J. Perkins, Akshay A. Shah, Michael David VanHeyst, Zhe Wu
  • Publication number: 20230343768
    Abstract: The technology generally relates to disaggregating memory from an application specific integrated circuit (“ASIC”) package. For example, a high-bandwidth memory (“HBM”) optics module package may be connected to an ASIC package via one or more optical links. The HBM optics module package may include HBM dies(s), HBM chiplet(s) and an optical chiplet. The optical chiplet may be configured to connect the HBM optics module to one or more optical fibers that form an optical link with one or more other components of the ASIC package. By including an optical chiplet in the HBM optics module package, the HBM optics module package may be disaggregated from an ASIC package.
    Type: Application
    Filed: November 22, 2022
    Publication date: October 26, 2023
    Inventors: Horia Alexandru Toma, Zuowei Shen, Hong Liu, Yujeong Shim, Biao He, Jaesik Lee, Georgios Konstadinidis, Teckgyu Kang, Igor Arsovski, Sukalpa Biswas
  • Publication number: 20230345412
    Abstract: This application provides a positioning method and a related device. The method includes: A positioning device receives a positioning start message, where the positioning start message is used to trigger the positioning device to position a to-be-positioned device; the positioning device records a displacement parameter generated in a movement process of the positioning device, where the displacement parameter includes a displacement direction and a displacement distance; the positioning device receives, in the movement process, a radio signal sent by the to-be-positioned device; and the positioning device obtains a relative position relationship between the positioning device and the to-be-positioned device based on the recorded displacement parameter and the radio signal sent by the to-be-positioned device.
    Type: Application
    Filed: June 29, 2023
    Publication date: October 26, 2023
    Inventors: Jia JIA, Jun CHEN, Hong LIU, Mingjie DONG
  • Patent number: 11799393
    Abstract: The application provides a dispersed carrier phase-shifting method and system. The method includes connecting at least two power modules to form a modular system; each power module including a control module for sampling at least twice a common state variate, signs of slopes of the common state variate at a first and second sampling time are opposite, and a reference time of the first sampling time for each control module is the same; and regulating a carrier frequency of the power module according to a relative size between a sampled values at the first and second sampling time. According to embodiments herein, carrier phase-shifting of modular system may be implemented without communication between respective modules. Under closed-loop control, optimal carrier phase-shifting can be automatically achieved under various duty ratios, thereby having good stability.
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: October 24, 2023
    Assignee: DELTA ELECTRONICS (SHANGHAI) CO., LTD.
    Inventors: Hong Liu, Wen Zhang, Wenfei Hu, Cheng Lu, Hongyang Wu
  • Patent number: 11795119
    Abstract: An inhibitor composition contains alkyl thiophosphoric triamide (or a mixture of alkyl thiophosphoric triamide and dicyandiamide), dissolved in a liquid medium comprising at least one organic solvent, at least one amine stabilizer and, optionally, at least one dye and/or at least one odor masking agent, is useful in making fertilizer compositions and in a method of fertilizing target plants.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: October 24, 2023
    Assignee: RHODIA OPERATIONS
    Inventors: Hong Liu, Jiamin Wu, Andre Gomes, Krish Shanmuga, Zhiyun Chen
  • Publication number: 20230312528
    Abstract: Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are inhibitors of Nav1.8 channel activity and may be useful in the treatment, prevention, management, amelioration, control and suppression of diseases mediated by Nav1.8 channel activity. The compounds of the present invention may be useful in the treatment, prevention or management of pain disorders, cough disorders, acute itch disorders, and chronic itch disorders.
    Type: Application
    Filed: June 5, 2023
    Publication date: October 5, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Ashok Arasappan, Ian M. Bell, Christopher James Bungard, Christopher S. Burgey, Jason M. Cox, Michael J. Kelly, III, Mark E. Layton, Hong Liu, Jian Liu, James J. Perkins, Akshay A. Shah, Michael David VanHeyst, Zhe Wu