Patents by Inventor Hongyan Chen

Hongyan Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220143623
    Abstract: A method of improving grinding, grading and capacity of ores by reducing a fineness content ratio ?0 in settled ores includes providing a two-stage ore grinding and grading system including a first fully closed circuit including a grinder and a hydrocyclone, or a two-stage ore grinding and grading system including a first-stage open circuit, and controlling parameters for ore grinding and grading as follows: controlling a dc an value of a point B on a separation cone of a second-stage ?500 mm hydrocyclone; controlling a fineness content ratio ?0 in settled ores; controlling a second-stage ore grinding and grading load Q2; and acquiring a first-stage grinding, grading and capacity Q of ores.
    Type: Application
    Filed: January 26, 2022
    Publication date: May 12, 2022
    Inventors: Yaoji LI, Chaozhu LIU, Haibing LI, Huilin SONG, Houchao LI, Wei DONG, Shuanggui CHEN, Hui ZHANG, Shirong ZONG, Shixiang FANG, Jianyun ZHAO, Chang LU, Ning LI, Hongyan LI, Shu FANG, Jialin ZI, Guang'ai XIONG
  • Patent number: 11286387
    Abstract: A curable composition comprising a mixture of homopolymers of an aliphatic polyisocyanate and a cycloaliphatic polyisocyanate, a polyester polyol or polyether polyol and a filler. The composition is particularly suitable for use in the manufacture of outdoor insulation system articles.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: March 29, 2022
    Inventors: Christian Beisele, Hongyan Chen, Satoru Hishikawa
  • Publication number: 20210395235
    Abstract: The present application relates to a compound as a TGF-? R1 inhibitor and application thereof. Specifically, provided are a compound of formula I, or an isomer, pharmaceutically acceptable salt, solvent, crystal, or prodrug thereof, preparation methods therefor, and pharmaceutical compositions comprising these compounds, and applications of these compounds or compositions in treating and/or preventing TGF-? R1-related diseases, such as cancer, tissue proliferation diseases, fibrosis, and inflammatory diseases. The compound represents a significant inhibitory activity for TGF-? R1 kinase, and is promising as a treatment agent for TGF-? R1-related diseases.
    Type: Application
    Filed: October 17, 2019
    Publication date: December 23, 2021
    Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong WANG, Liwen ZHAO, Yazhou WANG, Yan ZHANG, Xiaowei WANG, Hai WANG, Zhuang GUO, Kunzhi LV, Yujie CHANG, Hongyan CHEN, Guofeng XU
  • Patent number: 11186587
    Abstract: Disclosed are a class of compounds which are inhibitors of acetyl-CoA carboxylase (ACC) and the use thereof. In particular, provided are compounds as shown in formula I or isomers, pharmaceutically acceptable salts, solvates, crystals or prodrugs thereof, and methods for preparing the same, and pharmaceutical compositions comprising the compounds and the use of the compounds or compositions for treating and/or preventing diseases associated with ACC expression, such as fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases. The compound has a good inhibitory activity against ACC and shows good promise to be a therapeutic drug for fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: November 30, 2021
    Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong Wang, Liwen Zhao, Yazhou Wang, Xu Quan, Chunhuan Jiang, Hongyan Chen, Menghua Chen, Chao Li, Yexin Liao, Qi Liu, Chen Wang, Hai Wang, Shengwei Yang, Guochuang Zheng
  • Patent number: 10739921
    Abstract: A transparent conductive film includes a substrate having opposed first and second surfaces; a first optical adjustment layer formed on the first surface; a first transparent conductive layer formed on the first optical adjustment layer; a first metal layer formed on the first transparent conductive layer; a second optical adjustment layer formed on the second surface; a second transparent conductive layer formed on the second optical adjustment layer; and a second metal layer formed on the second transparent conductive layer. At least one of the first optical adjustment layer and the second optical adjustment layer comprises a plurality of particles therein, such that a plurality of protrusions corresponding to the plurality of particles are formed on a surface of at least one of the first metal layer and the second metal layer.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: August 11, 2020
    Assignee: NANCHANG O-FILM DISPLAY TECHNOLOGY CO., LTD
    Inventors: Hongyan Chen, Rongzhi Gu, Weiting Huang, Xiaowei Hou
  • Patent number: 10696820
    Abstract: A multiple component thermosetting epoxy resin composition comprising (A) at least one cycloaliphatic glycidyl-type epoxy resin without an ester group, (B) at least one curing agent selected from the group aliphatic amine, cycloaliphatic amine, and dicyandiamide, and (C) at least one silanized filler, which, in particular, is suitable for the manufacture of outdoor insulation system articles for electrical engineering by casting, potting, encapsulation, and impregnation processes, wherein said articles exhibit good mechanical, electrical and dielectrical properties, and can be used as insulators, bushings, switchgears and instrument transformers.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: June 30, 2020
    Assignee: HUNTSMAN INTERNATIONAL LLC
    Inventors: Christian Beisele, Zhijian Liu, Hongyan Chen, Satoru Hishikawa
  • Publication number: 20200165265
    Abstract: Disclosed are a class of compounds which are inhibitors of acetyl-CoA carboxylase (ACC) and the use thereof. In particular, provided are compounds as shown in formula I or isomers, pharmaceutically acceptable salts, solvates, crystals or prodrugs thereof, and methods for preparing the same, and pharmaceutical compositions comprising the compounds and the use of the compounds or compositions for treating and/or preventing diseases associated with ACC expression, such as fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases. The compound has a good inhibitory activity against ACC and shows good promise to be a therapeutic drug for fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases.
    Type: Application
    Filed: July 25, 2018
    Publication date: May 28, 2020
    Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong WANG, Liwen ZHAO, Yazhou WANG, Xu QUAN, Chunhuan JIANG, Hongyan CHEN, Menghua CHEN, Chao LI, Yexin LIAO, Qi LIU, Chen WANG, Hai WANG, Shengwei YANG, Guochuang ZHENG
  • Publication number: 20190095003
    Abstract: A transparent conductive film includes a substrate having opposed first and second surfaces; a first optical adjustment layer formed on the first surface; a first transparent conductive layer formed on the first optical adjustment layer; a first metal layer formed on the first transparent conductive layer; a second optical adjustment layer formed on the second surface; a second transparent conductive layer formed on the second optical adjustment layer; and a second metal layer formed on the second transparent conductive layer. At least one of the first optical adjustment layer and the second optical adjustment layer comprises a plurality of particles therein, such that a plurality of protrusions corresponding to the plurality of particles are formed on a surface of at least one of the first metal layer and the second metal layer.
    Type: Application
    Filed: July 27, 2018
    Publication date: March 28, 2019
    Applicant: NANCHAGN O-FILM DISPLAY TECHNOLOGY CO.,LTD
    Inventors: Hongyan CHEN, Rongzhi GU, Weiting HUANG, Xiaowei HOU
  • Publication number: 20180346717
    Abstract: A curable composition comprising (A) a mixture of homopolymers of polyisocyanates comprising (a1) from 50 wt % to 90 wt % of at least one homopolymer of an aliphatic poly-isocyanate, and (a2) from 10 wt % to 50 wt % of at least one homopolymer of a cycloaliphatic poly-isocyanate, each based on the total weight of (a1) and (a2), (B) at least one polyol selected from the group of polyether polyol and polyester polyol, (C) at least one filler selected from the group of quartz sand, quartz powder, silica, aluminium oxide, titanium oxide, zirconium oxide, Mg(OH)2, AI(OH)3, dolomite [CaMg (CO3)2], AIO(OH), silicon nitride, boron nitride, aluminium nitride, silicon carbide, boron carbide, chalk, calcium carbonate, barite, gypsum, hydromagnesite, zeolites, talcum, mica, kaolin and wollastonite, wherein the at least one filler may be silanized, which, in particular, is suitable for the manufacture of outdoor insulation system articles for electrical engineering by casting, potting, encapsulation, and impregnation
    Type: Application
    Filed: November 7, 2016
    Publication date: December 6, 2018
    Applicant: Huntsman Advanced Materials Licensing (Switzerland) GmbH
    Inventors: Christian BEISELE, Hongyan CHEN, Satoru HISHIKAWA
  • Patent number: 9963480
    Abstract: A novel nucleoside phosphoramidate compound of the formula below, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection, and having a good anti-HCV effect; a pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof:
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: May 8, 2018
    Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong Wang, Liwen Zhao, Xian Zhang, Sheng Bi, Yiping Gao, Hongyan Chen, Dezhong Wang, Yang Nan, Cang Zhang, Yuxiu Li, Di Zhang
  • Publication number: 20180118922
    Abstract: A multiple component thermosetting epoxy resin composition comprising (A) at least one cycloaliphatic glycidyl-type epoxy resin without an ester group, (B) at least one curing agent selected from the group aliphatic amine, cycloaliphatic amine, and dicyandiamide, and (C) at least one silanized filler, which, in particular, is suitable for the manufacture of outdoor insulation system articles for electrical engineering by casting, potting, encapsulation, and impregnation processes, wherein said articles exhibit good mechanical, electrical and dielectrical properties, and can be used as insulators, bushings, switchgears and instrument transformers.
    Type: Application
    Filed: March 10, 2016
    Publication date: May 3, 2018
    Inventors: Christian BEISELE, Zhijian LIU, Hongyan CHEN, Satoru HISHIKAWA
  • Patent number: 9512108
    Abstract: The present invention belongs to the field of chemical pharmaceuticals, and specifically relates to compounds represented by formula I having a 9,9,10,10-tetrafluoro-9,10-dihydrophenanthrene structure and being able to inhibit hepatitis C virus activity, or a pharmaceutically acceptable salt, isomer, solvate, crystal or prodrug of said compounds, a pharmaceutical composition containing said compounds, and an application of said compounds or composition in the preparation of a drug. The compounds of the present invention have a good HCV inhibitory effect.
    Type: Grant
    Filed: December 26, 2014
    Date of Patent: December 6, 2016
    Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong Wang, Liwen Zhao, Dezhong Wang, Haiping Zhou, Xian Zhang, Hongyan Chen, Di Zhang, Cang Zhang
  • Publication number: 20160297804
    Abstract: The present invention belongs to the field of chemical pharmaceuticals, and specifically relates to compounds represented by formula I having a 9,9,10,10-tetrafluoro-9,10-dihydrophenanthrene structure and being able to inhibit hepatitis C virus activity, or a pharmaceutically acceptable salt, isomer, solvate, crystal or prodrug of said compounds, a pharmaceutical composition containing said compounds, and an application of said compounds or composition in the preparation of a drug. The compounds of the present invention have a good HCV inhibitory effect.
    Type: Application
    Filed: December 26, 2014
    Publication date: October 13, 2016
    Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong WANG, Liwen ZHAO, Dezhong WANG, Haiping ZHOU, Xian ZHANG, Hongyan CHEN, Di ZHANG, Cang ZHANG
  • Patent number: 9255107
    Abstract: In the field of pharmaceutical chemistry compounds of general formula I having heteroaryl alkynyl moiety or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof, and pharmaceutical compositions including these compounds, as well as uses of these compounds and compositions thereof in the manufacture of a medicament. The compounds have a strong inhibitory effect on BCR-ABL tyrosine kinase and are useful for treating diseases, such as tumors.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: February 9, 2016
    Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong Wang, Liwen Zhao, Di Zhang, Feng Wu, Sheng Bi, Yiping Gao, Hongbin Chen, Hongyan Chen, Cang Zhang, Yang Nan, Yang Liu
  • Publication number: 20150361123
    Abstract: A novel nucleoside phosphoramidate compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection is provided. The pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof and a use of the compound or the composition in the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection. The compound has a good anti-HCV effect.
    Type: Application
    Filed: March 6, 2014
    Publication date: December 17, 2015
    Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD
    Inventors: Yong WANG, Liwen ZHAO, Xian ZHANG, Sheng BI, Yiping GAO, Hongyan CHEN, Dezhong WANG, Yang NAN, Cang ZHANG, Yuxiu LI, Di ZHANG
  • Publication number: 20150299202
    Abstract: In the field of pharmaceutical chemistry compounds of general formula I having heteroaryl alkynyl moiety or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof, and pharmaceutical compositions including these compounds, as well as uses of these compounds and compositions thereof in the manufacture of a medicament. The compounds have a strong inhibitory effect on BCR-ABL tyrosine kinase and are useful for treating diseases, such as tumors.
    Type: Application
    Filed: November 27, 2013
    Publication date: October 22, 2015
    Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong WANG, Liwen ZHAO, Di ZHANG, Feng WU, Sheng BI, Yiping GAO, Hongbin CHEN, Hongyan CHEN, Cang ZHANG, Yang NAN, Yang LIU
  • Publication number: 20150152088
    Abstract: The present invention belongs to the field of pharmaceutical chemistry, and specifically relates to compounds having an alkynyl heteroaromatic ring structure and pharmaceutically acceptable salts, stereoisomers, N-oxides, solvates, or prodrugs thereof, and pharmaceutical compositions comprising these compounds, as well as uses of these compounds and compositions in the manufacture of a medicament. The compounds of the present invention and the pharmaceutically acceptable salts, stereoisomers, N-oxides, solvates or prodrugs thereof and the pharmaceutical compositions comprising the compounds have better anti-tumor activity.
    Type: Application
    Filed: September 12, 2013
    Publication date: June 4, 2015
    Applicant: Nanjing Sanhome Pharmaceutical Co., Ltd.
    Inventors: Yong Wang, Liwen Zhao, Wenping Zhang, Hongyan Chen, Sheng Bi, Yiping Gao, Hongbin Chen, Yang Liu, Xin Xu, Cang Zhang
  • Publication number: 20130249741
    Abstract: An antenna and a terminal with an antenna are disclosed. The antenna is a strip planar antenna, which includes an intermediate frequency branch, a high frequency branch and a low frequency branch, where the intermediate frequency branch, the high frequency branch and the low frequency branch are independent of one another, the high frequency branch and the low frequency branch encircle the intermediate frequency branch; a feed point connecting line is disposed on the intermediate frequency branch; a first ground point connecting line is disposed on the high frequency branch; a second ground point connecting line is disposed on the low frequency branch, and the feed point connecting line, the first ground point connecting line and the second ground point connecting line are located at the same side of the antenna.
    Type: Application
    Filed: May 22, 2013
    Publication date: September 26, 2013
    Applicant: Huawei Device Co., Ltd.
    Inventors: Hongyan Chen, Yafang Yu, Shuhui Sun