Patents by Inventor Hongzhang Sun

Hongzhang Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11084790
    Abstract: The present invention provides a complex of formula (I) or a solvate thereof (wherein n is 1 to 4), a pharmaceutical composition, and use of the pharmaceutical composition in the prevention or treatment of surgical pain, intraoperative pain and postsurgical pain. The technical solution according to the present invention provides a medicament which can be produced by a simple production process and can stably release a local anesthetic in body for a long period. The medicament can be released for at least three days or more, which can prolong the analgesic effect on the postsurgical pain, can be used conveniently by the physician and the patient, and has a good treatment compliance.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: August 10, 2021
    Assignee: Fruithy Holdings Limited
    Inventors: Shanchun Zhang, Yihua Wang, Jiashi Peng, Kaisheng Cheng, Xiao Wang, Shu Gao, Hongzhang Sun, Xiaorong Lu
  • Publication number: 20210087144
    Abstract: The present invention provides a complex of formula (I) or a solvate thereof (wherein n is 1 to 4), a pharmaceutical composition, and use of the pharmaceutical composition in the prevention or treatment of surgical pain, intraoperative pain and postsurgical pain. The technical solution according to the present invention provides a medicament which can be produced by a simple production process and can stably release a local anesthetic in body for a long period. The medicament can be released for at least three days or more, which can prolong the analgesic effect on the postsurgical pain, can be used conveniently by the physician and the patient, and has a good treatment compliance.
    Type: Application
    Filed: March 26, 2018
    Publication date: March 25, 2021
    Inventors: Shanchun Zhang, Yihua Wang, Jiashi Peng, Kaisheng Cheng, Xiao Wang, Shu Gao, Hongzhang Sun, Xiaorong Lu
  • Patent number: 10568892
    Abstract: The present invention relates to the field of natural medicine and pharmaceutical chemistry, and in particular relates to a cycloartane tetracyclic triterpenoid compound (I), a preparation method thereof and the medical use thereof. The pharmacodynamic tests demonstrate that the compound of the present invention has a pharmacodynamic activity on heart and cerebral vessels and can be used to prevent or treat cardiovascular and/or cerebrovascular diseases such as arrhythmia, myocardial infarction, and coronary heart disease or the like.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: February 25, 2020
    Assignees: Hefei Cosource Pharmaceuticals Inc., Hefei Blooming Drug Safety Evaluation Co., Ltd.
    Inventors: Shanchun Zhang, Shu Gao, Xiaorong Lu, Hongzhang Sun, Yijun Bao, Bin Yang, Jiashi Peng
  • Publication number: 20190240238
    Abstract: The present invention relates to the field of natural medicine and pharmaceutical chemistry, and in particular relates to a cycloartane tetracyclic triterpenoid compound (I), a preparation method thereof and the medical use thereof. The pharmacodynamic tests demonstrate that the compound of the present invention has a pharmacodynamic activity on heart and cerebral vessels and can be used to prevent or treat cardiovascular and/or cerebrovascular diseases such as arrhythmia, myocardial infarction, and coronary heart disease or the like.
    Type: Application
    Filed: February 3, 2017
    Publication date: August 8, 2019
    Inventors: Shanchun Zhang, Shu Gao, Xiaorong Lu, Hongzhang Sun, Yijun Bao, Bin Yang, Jiashi Peng
  • Publication number: 20110224276
    Abstract: Optical isomers of phenylpropionic acid drugs are a mixture having R-type optical isomer and S-type optical isomer at a ratio of 10:1-1:10 by weight, wherein the ratio of 1:1 is excluded. A use of the optical isomers includes that the R-type optical isomer is used for manufacturing anti-inflammatory and analgesic drugs and the mixture having the R-type optical isomer and the S-type optical isomer at a ratio of 10:1-1:10 by weight, wherein the ratio of 1:1 is excluded, is used for manufacturing anti-inflammatory and analgesic drugs. The therapeutic indexes of anti-inflammatory and analgesic drugs of the present optical isomers are all higher than those of the S-type optical isomers and the racemate.
    Type: Application
    Filed: November 20, 2009
    Publication date: September 15, 2011
    Inventors: Tao Wang, Yan Geng, Zonggui Wang, Hongzhang Sun