Abstract: Disclosed herein are humanized antibodies, antigen-binding fragments thereof, and antibody conjugates, that are capable of specifically binding to certain biantennary Lewis antigens, which antigens are expressed in a variety of cancers. The presently disclosed antibodies are useful to target antigen-expressing cells for treatment or detection of disease, including various cancers. Also provided are polynucleotides, vectors, and host cells for producing the disclosed antibodies and antigen-binding fragments thereof. Pharmaceutical compositions, methods of treatment and detection, and uses of the antibodies, antigen-binding fragments, antibody conjugates, and compositions are also provided.

Abstract: A liquid dispenser having immersive motion graphics is provided and includes a base portion, a display portion, a liquid supply portion and an electrical control portion, where the display portion is disposed in an accommodating space formed by the base portion, such that when the electrical control portion controls the liquid supply portion to inject a liquid into a target object located in the accommodating space, the electrical control portion simultaneously controls the display portion to display a motion graphic in the accommodating space to generate an interaction between the motion graphic and the liquid. Therefore, consumers can be informed of rich beverage information and be provided with an immersive experience via the display of the motion graphic.

Abstract: The present invention relates to UNC13A cryptic exon antisense oligonucleotides (ASOs), pharmaceutical compositions containing them, and methods for treating, inhibiting, suppressing, and preventing neurological diseases with them.

Abstract: The present disclosure relates to an antibody or antigen-binding fragment thereof that specifically binds to a spike protein of SARS-CoV-2. The present disclosure also relates to a pharmaceutical composition, a method for treating and/or preventing diseases and/or disorders caused by a coronavirus in a subject in need thereof, and a method for detecting a coronavirus in a sample.

Abstract: A method includes obtaining Wi-Fi channel state information (CSI) data on a transmit antenna/receive antenna pair over a time period. The method also includes removing one or more anomalies present in the CSI data. The method also includes performing at least one of phase compensation and amplitude compensation on the CSI data to generate clean CSI data. The method also includes detecting a number of distinct respiration rates based on the clean CSI data. The method also includes, for each of the distinct respiration rates, determining a number of people that have that distinct respiration rate.

Abstract: A method includes receiving CSI data for at least one communication link between a first electronic device (ED1) and a Wi-Fi device in a 3D space. The method includes preprocessing the CSI data; and determining whether a motion of an object is detected within a threshold distance to the ED1 based on the preprocessed CSI data. The detection of the motion of the object corresponds to a determination that the object is present in the space. The detection of no motion of the object corresponds to a determination that the object is not present in the space. The method includes outputting at least one of: a first indicator indicating that the space is empty, in response to the determination that the object is not present in the space; or a second indicator indicating that the space is occupied, in response to the determination that the object is present in the space.

Abstract: The present disclosure provides a defect inspecting method and a defect inspecting system configured to inspect a memory device. The defect inspecting method includes the operations of: resetting the memory device from a power on state; initializing the memory device; performing a plurality of write operations to a memory cell array of the memory device according to a test pattern; performing a plurality of read operations to the memory cell array of the memory cell to generate a readout pattern; and determining whether a defect existed in the memory device according to the readout pattern.

Abstract: An inverter device includes a converter circuit and a filter. The converter circuit converts a DC input voltage into an AC intermediate voltage based on six control signals, and includes first and second converters. Each of the first and second converters includes three switches, two diodes and a coupled inductor circuit. The switches of the first converter operate respectively based on three of the control signals. The switches of the second converter operate respectively based on the other three of the control signals. The filter filters the AC intermediate voltage to generate an AC output voltage.

Abstract: A wearable ultrasonic therapeutic device controlled by a mobile electronic device is provided, which includes a mobile device, at least one ultrasonic probe module and a strap. The mobile device has a mobile device control interface for setting ultrasonic parameters and displaying an echo wave through a specific software interface of the mobile device. The ultrasonic probe module includes at least one ultrasonic transducer and a control circuit corresponding thereto. The ultrasonic transducer generates and receives an ultrasonic wave. The control circuit has the functions of generating/receiving signals, phase regulation, power amplification and matching. One end of the ultrasonic probe module is electrically connected to the mobile device and the other end of the ultrasonic probe module is connected to the strap.

Abstract: A communication device includes a radio transceiver and a collision detection device. The radio transceiver is configured to receive a wireless signal which includes an acknowledgment packet from a wireless communication channel. The acknowledgment packet includes acknowledgment information which corresponds to a plurality of transmitted packets. The collision detection device is coupled to the radio transceiver and configured to receive the acknowledgment packet, determine whether collision has occurred in the wireless communication channel according to the acknowledgment information corresponding to the transmitted packets and accordingly generate a detection result. The collision detection device determines whether collision has occurred according to a distribution of the acknowledgment information having a predetermined acknowledgment status.

Abstract: Methods of spatially directing the orientation and placement of multiple block copolymer (BCP) domains on isolated regions of a substrate are described. The methods involve epitaxially directing the assembly of BCP domains using spatial boundaries between regions with different surface composition, formed at the edges of isolated chemical regions on a background chemistry. Multiple vertical domains of BCP order on the isolated region, self-aligned in a direction parallel to edges of the isolated region. In some embodiments, vertical domains order on multiple isolated regions of a first chemistry of a chemical contrast pattern with horizontal domains on the regions of a second (background) chemistry of the chemical contrast pattern. Also provided herein are compositions resulting from the methods.

Abstract: A semiconductor structure is provided, and the semiconductor structure includes a substrate, and an active area is defined thereon, a gate structure spanning the active area, wherein the overlapping range of the gate structure and the active area is defined as an overlapping region, and the overlapping region includes four corners, and at least one salicide block covering the four corners of the overlapping region.

Abstract: The present invention relates to an automatic injection training device comprising an elongated housing having a distal end and an opposite proximal end and extending along a longitudinally axis (L); a tubular demo container axially and rotationally fixed relative to the elongated housing and having a tubular wall extending along the longitudinally axis (L); a reloadable plunger assembly comprising a plunger rod which is movable in the demo container between a first and a second position and a first energy accumulating element configured to move the plunger rod from the first to the second position; an actuation assembly configured to hold the plunger rod in the first position and to release the plunger rod from the first position.

Abstract: A semiconductor structure is provided, and the semiconductor structure includes a substrate, and an active area is defined thereon, a gate structure spanning the active area, wherein the overlapping range of the gate structure and the active area is defined as an overlapping region, and the overlapping region includes four corners, and at least one salicide block covering the four corners of the overlapping region.

Abstract: A semiconductor device includes a substrate, a first isolation structure, a second isolation structure and a dummy pattern. The substrate includes a first part surrounding a second part at a top view. The first isolation structure is disposed between the first part and the second part, to isolate the first part from the second part. The second isolation structure is disposed at at least one corner of the first part. The dummy pattern is disposed on the second isolation structure. The present invention also provides a method of forming said semiconductor device.

Abstract: The present invention relates to PIKFYVE antisense oligonucleotides (ASOs), pharmaceutical compositions containing them, and methods for treating, inhibiting, suppressing, and preventing neurological diseases with them.

Abstract: Disclosed herein are humanized antibodies, antigen-binding fragments thereof, and antibody conjugates, that are capable of specifically binding to certain biantennary Lewis antigens, which antigens are expressed in a variety of cancers. The presently disclosed antibodies are useful to target antigen-expressing cells for treatment or detection of disease, including various cancers. Also provided are polynucleotides, vectors, and host cells for producing the disclosed antibodies and antigen-binding fragments thereof. Pharmaceutical compositions, methods of treatment and detection, and uses of the antibodies, antigen-binding fragments, antibody conjugates, and compositions are also provided.

Abstract: Disclosed are a channel estimation method and system, a device, and a storage medium. The method includes: acquiring a channel type and a channel expression under a multi-user environment first, and then according to the channel type, determining a training sequence set, training sequences in the training sequence set being zero circular convolution sequences; and according to the channel type, the channel expression and the training sequence set, determining an output sequence.

Abstract: A fabricating method of reducing photoresist footing includes providing a silicon nitride layer. Later, a fluorination process is performed to graft fluoride ions onto a top surface of the silicon nitride layer. After the fluorination process, a photoresist is formed to contact the top surface of the silicon nitride layer. Finally, the photoresist is patterned to remove at least part of the photoresist contacting the silicon nitride layer.

Abstract: An electronic device includes a first conductive layer including a first metal mesh including a first metal line segment, a second metal line segment and a first compensating line segment. The first metal line segment extends along a first direction and has a first end, and the second metal line segment extends along the first direction and has a second end, wherein a first breakpoint exists between the first end and the second end. The first compensating line segment is separated from and electrically insulated from the first metal line segment and the second metal line segment, the first compensating line segment does not completely overlap the first breakpoint, and a minimum distance between the first breakpoint and each first segment end of the first compensating line segment is less than or equal to 50 ?m.