Abstract: The present disclosure provides an internal ring gear, a driving assembly having the internal ring gear, and an application device employing the driving assembly. The internal ring gear includes at least two ring gears integrally arranged in parallel at an inner surface of a single housing.

Abstract: A switch mode power supply includes an error amplifier, an oscillator, a pulse width modulation logic circuit, and an output stage. The oscillator includes a current generator that receives a clock signal and provides a current proportional to a frequency of the clock signal, a current mirror having an input coupled to the output of the current generator, and a first capacitor having a first terminal coupled to an output of the current mirror and providing a ramp signal, and a second terminal coupled to power supply voltage terminal. The pulse width modulation logic circuit compares the output of the error amplifier with the ramp signal, and generates a high- and low-side drive signals respectively to first and second outputs in response to the comparing. The output stage is responsive to the high- and low-side drive signals for alternatively coupling a switch terminal between an input voltage terminal and ground.

Abstract: A ramp generator includes a current generator, a current mirror, and a first capacitor. The current generator has an input for receiving a clock signal, and an output for providing a current proportional to a frequency of the clock signal using a first transistor having first and second current electrodes and a control electrode, an amplifier that establishes a reference voltage on the second current electrode of the first transistor, and a variable resistor coupled between the second current electrode of the second transistor and ground whose resistance is set according to the frequency of the clock signal. The current mirror has an input coupled to the first terminal of the first transistor, and a second terminal. The first capacitor has a first terminal coupled to the output of the current mirror and providing a ramp signal, and a second terminal coupled to the first power supply voltage terminal.

Abstract: The present disclosure relates to compositions, methods and devices for treating, reducing or preventing one or more eye disorders, particularly dry eye disorders, in a subject by administering an amount of one or more fatty acids and/or fatty acid esters therapeutically effective to inhibit lipase activity while permitting bacterial growth or without substantially altering the dynamic microbial community of the eye. Typically, the fatty acids and/or fatty acid esters are C8 to C16 fatty acids and/or fatty acid esters.

Abstract: An optical fiber connector device includes an optical fiber connector and an insert unit. The insert unit hash a housing and a connecting mechanism. The housing surrounds an axis, and has an outer wall, a surrounding wall, and a cover member. The outer wall defines a first insert opening on the axis, and has a main opening spaced apart from the axis. The outer wall and the surrounding wall are molded as one piece. The cover member covers removably the main opening. The connecting mechanism has a first connecting member surrounded by the outer wall and connected to the optical fiber connector, and a second connecting member surrounded by the surrounding wall, coupled to the first connecting member, and adapted to be connected to another optical fiber connector.

Abstract: Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.

Abstract: The present disclosure relates to compositions, methods and devices for treating, reducing or preventing one or more eye disorders, particularly dry eye disorders, in a subject by administering an amount of one or more fatty acids and/or fatty acid esters therapeutically effective to inhibit lipase activity while permitting bacterial growth or without substantially altering the dynamic microbial community of the eye. Typically, the fatty acids and/or fatty acid esters are C8 to C16 fatty acids and/or fatty acid esters.

Abstract: The invention provides a method of treating alveolar bone loss involving administration of a sclerostin inhibitor to a subject in need thereof.

Abstract: A computer identifies a first participant and a one or more additional participants associated with a collaboration through an electronic communication application that includes messaging content, identifies a first set of one or more keywords within the messaging content between the first participant and the one or more additional participants, retrieves a first set of historical information based at least in part on the first set of one or more keywords, the first participant and the one or more additional participants, generates a first instance of historical results that includes a multi-dimensional cube that graphs the first set of historical information with respect to the first set of one or more keywords, the first participant and the one or more additional participants, and a time frame, and provides the first instance of historical results to the first participant.

Abstract: An optical fiber connector is for linking a standard connector head member and a lucent connector tail member, and includes a first connecting member and a second connecting member. The first connecting member is adapted to be detachably connected to the standard connector head member, and has a first hollow body that defines a first passage. The second connecting member is adapted to be detachably coupled to the lucent connector tail member, is connected to the first connecting member, and has a second hollow body that defines a second passage. The second passage is in spatial communication with the first passage and has a diameter that is 1.3 millimeters. The first connecting member and the second connecting member are molded as one piece.

Abstract: The present invention provides antibodies and immunologically functional fragments thereof that specifically bind DKK1 polypeptides. Methods for preparing such antibodies or fragments thereof as well as physiologically acceptable compositions containing the antibodies or fragments are also provided. Use of the antibodies and fragments to treat various diseases are also disclosed.

Abstract: The invention relates to the treatment of bone disorders. In particular, the invention provides an approach involving administration of a high initial dose or doses of an sclerostin antibody to bring about a rapid increase in bone formation, followed by administration of lowers doses of the antibody to give a sustained lower rate of bone formation after the initial burst of bone formation. The invention also provides an approach involving decreasing dosing frequency with such an antibody to control bone formation. The approaches may be used in particular in those subjects who would benefit most from such an initial rapid burst of bone formation. Examples of such subjects include subjects who have been recently diagnosed or are experiencing severe symptoms of the disorder, as well as those subjects who have been administered a different treatment for the bone disorder which is proving ineffective. The approaches may be used in combination with each other.

Abstract: The invention provides a method of treating alveolar bone loss involving administration of a sclerostin inhibitor to a subject in need thereof.

Abstract: The present disclosure provides an internal ring gear, a driving assembly having the internal ring gear, and an application device employing the driving assembly. The internal ring gear includes at least two ring gears integrally arranged in parallel at an inner surface of a single housing.

Abstract: Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.

Abstract: The present invention provides antibodies and immunologically functional fragments thereof that specifically bind DKK1 polypeptides. Methods for preparing such antibodies or fragments thereof as well as physiologically acceptable compositions containing the antibodies or fragments are also provided. Use of the antibodies and fragments to treat various diseases are also disclosed.

Abstract: An optical fiber connector for connecting to an optical fiber cable includes a shell, a hollow guiding device, and a socket device. The hollow guiding device is connected to the shell. The socket device includes a hollow socket unit and a ferrule. The socket unit is formed as one piece and is detachably connected to an end of the guiding device opposite to the shell such that the optical fiber cable extends through the guiding device and the shell into the socket unit. The ferrule is disposed in the socket unit and is for connecting to one end of the optical fiber cable.

Abstract: A ramp generator includes a current generator, a current mirror, and a first capacitor. The current generator has an input for receiving a clock signal, and an output for providing a current proportional to a frequency of the clock signal using a first transistor having first and second current electrodes and a control electrode, an amplifier that establishes a reference voltage on the second current electrode of the first transistor, and a variable resistor coupled between the second current electrode of the second transistor and ground whose resistance is set according to the frequency of the clock signal. The current mirror has an input coupled to the first terminal of the first transistor, and a second terminal. The first capacitor has a first terminal coupled to the output of the current mirror and providing a ramp signal, and a second terminal coupled to the first power supply voltage terminal.

Abstract: Disclosed are an apparatus for cooling a server cabinet, a server cabinet apparatus, and an Internet data center. The apparatus includes: a bracket and a cooling device; where the bracket is positioned below one or a plurality of server cabinets, and the cooling device is positioned in the bracket, and cools the server cabinet on the bracket. The apparatus for cooling a server is positioned below one or a plurality of server cabinets, such that all the server cabinets in a large-scale Internet data center are effectively cooled, and in addition, resources are saved.

Abstract: A data center micro-module includes: an enclosure, and a cabinet system, a power supply system, and a cooling system that are inside the enclosure. The cabinet system installs a computing server, the power supply system supplies power for the computing server and the cooling system, and the cooling system cools the computing server; and the enclosure is further externally provided with an interface configured to connect to another data center micro-module or connection apparatus. The foregoing data center micro-module integrates the power supply system, the cooling system and the computing server into a same module, and therefore can be directly manufactured in a factory. When a data center is built, the data center micro-modules only need to be combined and assembled, which greatly reduces a construction cycle of the data center, and the hardware architecture may be flexibly changed according to a specific deployment requirement.