Abstract: A diffuser, an airflow generating apparatus, and an electrical device are provided. The airflow generating apparatus includes a motor; an impeller including blades with air passages formed therebetween; and a diffuser including diffusing vanes with diffusing channels formed therebetween. In a flow region defined between a terminating end of one diffusing vane and a starting end of another adjacent diffusing vane, an intersection line between a bottom of the diffusing channel between the two diffusing vanes and its circumferential section includes a front arcuate line segment and a subsequent straight line segment, the arcuate line segment extends curvedly, outwardly and downwardly from or from adjacent an inlet end of the diffusing channel, the straight line segment connects to the arcuate line segment and extends to an outlet end of the diffusing channel. The diffusing channel is designed to improve the operating efficiency of the airflow generating apparatus.

Abstract: A fan of a vacuum cleaner includes a motor, an impeller, and a diffuser. The diffuser includes a bottom plate and guide vanes disposed on the bottom plate. The guide vanes are evenly spaced and arranged along a circumferential direction of the bottom plate. Each guide vane extends obliquely from an inner edge to an outer edge of the bottom plate. An outer end of each guide vane extends beyond the outer edge of the bottom plate. Each guide vane is deflected an angle of 30 to 70 degrees with respect to a tangential direction of the bottom plate at the inner end of the guide vane. The outer end of each guide vane is deflected an angle of 35 to 120 degrees along a circumferential direction with respect to the inner end of the guide vane.

Abstract: A data visualization metrics explorer can be provided using JSON and hypertext. When an element of a grid row is selected, a new metrics explorer blade can be opened. A filter can be applied so that only information associated with the selected element is presented. Additional filters may also be applied to the data that is displayed. Progressive, iterative filtering can occur. The links between blades can be specified using JSON and hypertext. Multi-linking and re-use of individual JSON files can be performed by linking the JSON files together into a web. The web of visualization can be used to construct a web of visualization actions enabling data visualization exploration.

Abstract: A diffuser, an airflow generating apparatus, and an electrical device are provided. The airflow generating apparatus includes a motor; an impeller including blades with air passages formed therebetween; and a diffuser including diffusing vanes with diffusing channels formed therebetween. In a flow region defined between a terminating end of one diffusing vane and a starting end of another adjacent diffusing vane, an intersection line between a bottom of the diffusing channel between the two diffusing vanes and its circumferential section includes a front arcuate line segment and a subsequent straight line segment, the arcuate line segment extends curvedly, outwardly and downwardly from or from adjacent an inlet end of the diffusing channel, the straight line segment connects to the arcuate line segment and extends to an outlet end of the diffusing channel. The diffusing channel is designed to improve the operating efficiency of the airflow generating apparatus.

Abstract: A fan of a vacuum cleaner includes a motor, an impeller, and a diffuser. The diffuser includes a bottom plate and guide vanes disposed on the bottom plate. The guide vanes are evenly spaced and arranged along a circumferential direction of the bottom plate. Each guide vane extends obliquely from an inner edge to an outer edge of the bottom plate. An outer end of each guide vane extends beyond the outer edge of the bottom plate. Each guide vane is deflected an angle of 30 to 70 degrees with respect to a tangential direction of the bottom plate at the inner end of the guide vane. The outer end of each guide vane is deflected an angle of 35 to 120 degrees along a circumferential direction with respect to the inner end of the guide vane.

Abstract: The present invention provides a method and apparatus of managing a storage array. The method comprises: striping the storage array to form a plurality of stripes; selecting F storage chunks from each stripe as local parity chunks, and selecting another L storage chunks from the storage array as global parity chunks; performing (F+L) fault tolerant erasure coding on all data chunks in a stripe to generate (F+L) groups of parity data, and storing F groups of parity data therein into the F local parity chunks; performing cross-stripe operation on another L groups of parity data to generate L groups of global parity data, and storing them into the L global parity chunks, respectively. The apparatus corresponds to the method. With the invention, a plurality of errors in the storage array can be detected and/or recovered to improve fault tolerance and space utilization of the storage array.

Abstract: The present invention provides a method and apparatus of managing a storage array. The method comprises: striping the storage array to form a plurality of stripes; selecting F storage chunks from each stripe as local parity chunks, and selecting another L storage chunks from the storage array as global parity chunks; performing (F+L) fault tolerant erasure coding on all data chunks in a stripe to generate (F+L) groups of parity data, and storing F groups of parity data therein into the F local parity chunks; performing cross-stripe operation on another L groups of parity data to generate L groups of global parity data, and storing them into the L global parity chunks, respectively. The apparatus corresponds to the method. With the invention, a plurality of errors in the storage array can be detected and/or recovered to improve fault tolerance and space utilization of the storage array.

Abstract: The present invention provides a method and apparatus of managing a storage array. The method comprises: striping the storage array to form a plurality of stripes; selecting F storage chunks from each stripe as local parity chunks, and selecting another L storage chunks from the storage array as global parity chunks; performing (F+L) fault tolerant erasure coding on all data chunks in a stripe to generate (F+L) groups of parity data, and storing F groups of parity data therein into the F local parity chunks; performing cross-stripe operation on another L groups of parity data to generate L groups of global parity data, and storing them into the L global parity chunks, respectively. The apparatus corresponds to the method. With the invention, a plurality of errors in the storage array can be detected and/or recovered to improve fault tolerance and space utilization of the storage array.

Abstract: The present invention provides a method and apparatus of managing a storage array. The method comprises: striping the storage array to form a plurality of stripes; selecting F storage chunks from each stripe as local parity chunks, and selecting another L storage chunks from the storage array as global parity chunks; performing (F+L) fault tolerant erasure coding on all data chunks in a stripe to generate (F+L) groups of parity data, and storing F groups of parity data therein into the F local parity chunks; performing cross-stripe operation on another L groups of parity data to generate L groups of global parity data, and storing them into the L global parity chunks, respectively. The apparatus corresponds to the method. With the invention, a plurality of errors in the storage array can be detected and/or recovered to improve fault tolerance and space utilization of the storage array.

Abstract: A method is provided for quantifying endogenous sphingolipids in a biological system. The method includes preparing one or more isotope labeled amino acids; introducing the isotope labeled amino acids into a biological system; extracting and separating a sphingolipid-containing fraction from the biological system; and quantifying the amount of endogenous sphingolipids in the biological system. The isotope-labeled amino acid may include a non-essential amino acid, and the method may further include adding an amino acid synthesis inhibitor into the biological system. Systems and kits for quantifying endogenous sphingolipids also are disclosed.

Abstract: The present disclosure relates to chemical compounds and their use in human therapy. A specific embodiment relates to compounds of Formula (I) or an isomer, a pharmaceutically acceptable salt or solvate thereof and pharmaceutically acceptable formulations comprising said compounds useful for the treatment or prevention of conditions mediated by tachykinins and/or selective inhibition of serotonin reuptake transporter protein. The compounds act as dual NK-1 antagonists and selective serotonin reuptake inhibitors.

Abstract: The present disclosure relates to chemical compounds and their use in human therapy. A specific embodiment of the disclosure relates to compounds of Formula (I); or an isomer, a pharmaceutically acceptable salt or solvate thereof or a pharmaceutically acceptable formulation comprising said compounds are useful for the useful for the treatment or prevention of conditions mediated by tachykinins and/or selective inhibition of serotonin reuptake transporter protein. The compounds act as dual NK-1 antagonists and selective serotonin reuptake inhibitors.

Abstract: The present disclosure relates to chemical compounds and their use in treatment of human diseases. A particular embodiment relates to compounds of Formula (I) or an isomer, a pharmaceutically acceptable salts or solvates thereof or a pharmaceutically acceptable formulation comprising said compounds are useful for the treatment or prevention of conditions mediated by tachykinins and/or selective inhibition of serotonin reuptake transporter protein. The compounds act as dual NK-1 antagonists and selective serotonin reuptake inhibitors.

Abstract: The present invention provides novel 3-heterocyclic benzylamides and related derivatives having the general Formula I wherein R1, R2, R3, R4, R5, R6, A and Het are as defined in the specification, or a nontoxic pharmaceutically acceptable salt, solvate or hydrate thereof which are openers or activators of KCNQ potassium channels. The present invention also provides pharmaceutical compositions comprising said novel 3-heterocyclic benzylamides and to the method of treatment of disorders sensitive to KCNQ potassium channel opening activity such as migraine or a migraine attack, bipolar disorders, epilepsy, acute and chronic pain and anxiety.

Abstract: The present disclosure relates to chemical compounds and their use in human therapy. In a specific embodiment, compounds of Formula (I) or an isomer, a pharmaceutically acceptable salt or solvate thereof or a pharmaceutically acceptable formulation comprising said compounds useful for the treatment or prevention of conditions mediated by tachykinins and/or selective inhibition of serotonin reuptake transporter protein. The compounds act as dual NK-1 antagonists and selective serotonin reuptake inhibitors.

Abstract: The present invention provides novel aryl hydroxyethyl amides and related derivatives having the general Formula I wherein R1, R2, R3, R4, R5, R6, R7 and A are as defined in the specification, or a nontoxic pharmaceutically acceptable salt, solvate or hydrate thereof which are openers or activators of KCNQ potassium channels. The present invention also provides pharmaceutical compositions comprising said aryl hydroxyethyl amides and to the method of treatment of disorders sensitive to KCNQ potassium channel opening activity such as migraine or a migraine attack, bipolar disorders, epilepsy, acute and chronic pain and anxiety.

Abstract: The present disclosure relates to chemical compounds and their use in human therapy. A specific embodiment of the disclosure relates to compounds of Formula (I); or an isomer, a pharmaceutically acceptable salt or solvate thereof or a pharmaceutically acceptable formulation comprising said compounds are useful for the useful for the treatment or prevention of conditions mediated by tachykinins and/or selective inhibition of serotonin reuptake transporter protein. The compounds act as dual NK-1 antagonists and selective serotonin reuptake inhibitors.

Abstract: The present disclosure relates to chemical compounds and their use in human therapy. A specific embodiment relates to compounds of Formula (I) or an isomer, a pharmaceutically acceptable salt or solvate thereof and pharmaceutically acceptable formulations comprising said compounds useful for the treatment or prevention of conditions mediated by tachykinins and/or selective inhibition of serotonin reuptake transporter protein. The compounds act as dual NK-1 antagonists and selective serotonin reuptake inhibitors.

Abstract: The present disclosure relates to chemical compounds and their use in treatment of human diseases. A particular embodiment relates to compounds of Formula (I) or an isomer, a pharmaceutically acceptable salts or solvates thereof or a pharmaceutically acceptable formulation comprising said compounds are useful for the treatment or prevention of conditions mediated by tachykinins and/or selective inhibition of serotonin reuptake transporter protein. The compounds act as dual NK-1 antagonists and selective serotonin reuptake inhibitors.

Abstract: The present disclosure relates to chemical compounds and their use in human therapy. In a specific embodiment, compounds of Formula (I) or an isomer, a pharmaceutically acceptable salt or solvate thereof or a pharmaceutically acceptable formulation comprising said compounds useful for the treatment or prevention of conditions mediated by tachykinins and/or selective inhibition of serotonin reuptake transporter protein. The compounds act as dual NK-1 antagonists and selective serotonin reuptake inhibitors.