Patents by Inventor Huaping Hu

Huaping Hu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridines and pyridine N-oxides as modulators of thrombin
    Patent number: 7829584
    Abstract: The present invention describes compounds of Formula I: wherein W, X, Y, Z, and Q are defined herein, or a pharmaceutically acceptable salt thereof, for the prophylaxis, or treatment of diseases and conditions related to thrombin activity in a mammal.
    Type: Grant
    Filed: March 13, 2007
    Date of Patent: November 9, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mark R. Player, Tianbao Lu, Huaping Hu, Xizhen Zhu, Christopher Teleha, Kevin Kreutter
  • Imidazo[4,5-]pyrazinone inhibitors of protein kinases
    Patent number: 7608622
    Abstract: The invention is directed to compounds of Formula I: wherein Q, Y, A are set forth in the specification, as well as solvates, hydrates, tautomers or pharmaceutically acceptable salts thereof, that inhibit protein kinases, especially Aurora-1, Aurora-2 and Aurora-3 kinases.
    Type: Grant
    Filed: September 23, 2005
    Date of Patent: October 27, 2009
    Assignee: Janssen Pharmaceutica NV
    Inventors: Jian Liu, Raymond J. Patch, Mark R. Player, Huaping Hu
  • 5-OXO-5,8-DIHYDRO-PYRIDO-PYRIMIDINES AS INHIBITORS OF C-FMS KINASE
    Publication number: 20080114007
    Abstract: The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I: or a salt, stereoisomer, tautomer, crystalline, polymorph, amorphous, solvate, hydrate, ester, prodrug or metabolite form thereof, wherein A, Y, Z, R101 and R200 are described in the specification.
    Type: Application
    Filed: October 19, 2007
    Publication date: May 15, 2008
    Inventors: Mark Player, William Parsons, Hui Huang, Daniel Hutta, Huaping Hu, James Rinker
  • PYRIDINES AND PYRIDINE N-OXIDES AS MODULATORS OF THROMBIN
    Publication number: 20070225282
    Abstract: The present invention describes compounds of Formula I: wherein W, X, Y, Z, and Q are defined herein, or a pharmaceutically acceptable salt thereof, for the prophylaxis, or treatment of diseases and conditions related to thrombin activity in a mammal.
    Type: Application
    Filed: March 13, 2007
    Publication date: September 27, 2007
    Inventors: Mark Player, Tianbao Lu, Huaping Hu, Xizhen Zhu, Christopher Teleha, Kevin Kreutter