Patents by Inventor Huazhe LIU

Huazhe LIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250073716
    Abstract: The present disclosure provides a digital microfluidic nucleic acid detection chip, detection method, and detection apparatus. The digital microfluidic nucleic acid detection chip includes: a first substrate and a second substrate assembled with the first substrate, and a cavity formed between the first substrate and the second substrate includes a functional region (AC), which is configured to perform a nucleic acid detection processing on a droplet to be detected and obtain a hybridization color development signal for indicating whether a target gene exists in the droplet to be detected; the first substrate at least includes a plurality of drive units, which are configured to drive the droplet to be detected to move, a volume of the droplet to be detected is 10 ?l to 200 ?l, and a dimension of a drive unit is 2 mm to 100 mm in a moving direction of the droplet to be detected.
    Type: Application
    Filed: November 24, 2022
    Publication date: March 6, 2025
    Inventors: Le GU, Yingying ZHAO, Bolin FAN, Yongjia GAO, Li YANG, Huazhe LIU
  • Publication number: 20240424496
    Abstract: Provided in the present disclosure are a digital micro-fluidic apparatus, a driving method therefor, and the use thereof. The digital micro-fluidic apparatus comprises a digital micro-fluidic chip, the digital micro-fluidic chip at least comprising a drive electrode and a reference electrode, and the reference electrode being configured to write in a first reference voltage. The drive electrode is configured to alternately write in a first scanning voltage and a second scanning voltage so as to be alternately in an actuated state and a non-actuated state. In the actuated state, the drive electrode is configured to actuate composite liquid drops present therein; and in the non-actuated state, the drive electrode is configured to not actuate the composite liquid drops present therein.
    Type: Application
    Filed: September 25, 2023
    Publication date: December 26, 2024
    Inventors: Yingying ZHAO, Le GU, Bolin FAN, Yongjia GAO, Huazhe LIU, Li YANG
  • Publication number: 20240316561
    Abstract: Provided are a microfluidic substrate, a microfluidic chip, and an assay device. The microfluidic substrate includes: a base substrate; a conductive layer arranged on the base substrate, patterns of the conductive layer includes one or more electrode patterns and one or more trace patterns, an orthogonal projection of at least a portion of each trace pattern onto the base substrate is on one side of an orthogonal projection of a corresponding electrode pattern onto the base substrate with a minimum spacing of greater than or equal to 4 micrometers from an outer contour of the electrode pattern.
    Type: Application
    Filed: July 29, 2022
    Publication date: September 26, 2024
    Applicants: Beijing BOE Sensor Technology Co., Ltd., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Bolin Fan, Le Gu, Yongjia Gao, Yingying Zhao, Li Yang, Huazhe Liu
  • Patent number: 11155866
    Abstract: The present disclosure relates to a gene sequencing structure, chip, system, and method. The gene sequencing structure includes: a first electrode and a second electrode spaced apart from each other, a semiconductor layer, a sensing electrode, an insulating layer, and a sensitive film layer. The first electrode is connected to the second electrode via the semiconductor layer, the sensing electrode is in contact with the sensitive film layer, and the insulating layer isolates each of the sensitive film layer and the sensing electrode from each of the first electrode, the second electrode, and the semiconductor layer, wherein the sensitive film layer generates charges in response to receiving ions generated by base pairing during gene sequencing.
    Type: Grant
    Filed: February 11, 2018
    Date of Patent: October 26, 2021
    Assignees: BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Peizhi Cai, Fengchun Pang, Huazhe Liu
  • Publication number: 20200299765
    Abstract: The present disclosure relates to a gene sequencing structure, chip, system, and method. The gene sequencing structure includes: a first electrode and a second electrode spaced apart from each other, a semiconductor layer, a sensing electrode, an insulating layer, and a sensitive film layer. The first electrode is connected to the second electrode via the semiconductor layer, the sensing electrode is in contact with the sensitive film layer, and the insulating layer isolates each of the sensitive film layer and the sensing electrode from each of the first electrode, the second electrode, and the semiconductor layer, wherein the sensitive film layer generates charges in response to receiving ions generated by base pairing during gene sequencing.
    Type: Application
    Filed: February 11, 2018
    Publication date: September 24, 2020
    Inventors: Peizhi CAI, Fengchun PANG, Huazhe LIU
  • Publication number: 20170225997
    Abstract: The invention discloses a liquid crystal screen glass cutting method and apparatus to solve the unhealthy problem of being broken or serrated to be produced for the liquid crystal screen glass at intersections of cutting marks in different directions in the cutting procedure.
    Type: Application
    Filed: March 13, 2015
    Publication date: August 10, 2017
    Applicants: Beijing BOE Optoelectronics Technology Co., Ltd., BOE Technology Group Co., Ltd.
    Inventors: Xiangde MENG, Jun HU, Huazhe LIU, Guohua LV, Jinbo MA