Abstract: The preparation and colloidal gold nanoparticles deposited using a wet-chemical, three-phase ligand-exchange procedure carried out at room temperature on anodic alumina oxide to enhance detection of materials using Surface-enhanced Raman Scattering (SERS) is disclosed.

Abstract: A meter reading system comprises a sensor unit (2) containing a first camera (10) and at least a second camera (10?), the first camera focussed on a first area of a meter display (32) and the said second camera focussed on a second area of the meter display (32), the cameras arranged so that the area consisting of said first and second areas can be captured.

Abstract: Described is a process for producing a mutant bacterium which exhibits improved survival and/or growth under a selected growth condition, the process comprising the steps of: (a) generating a pool of mutant bacteria by transposon mutagenesis with an activating transposon (TnA), wherein the TnA comprises a promoter capable of increasing transcription of a gene at or near its insertion site; (b) growing bacteria from the mutant pool under the selected growth condition and under one or more reference conditions to produce two or more test cultures; and (c) comparing the distribution of TnA insertions between test cultures to identify a first class of genes which are disadvantageous for growth and/or survival under the selected growth condition and a second class of genes which are advantageous for growth and/or survival under the selected growth condition.

Abstract: A transparent substrate that encodes data therein having optically readable identification indicia corresponding to identifying information regarding the substrate. The optically readable identification indicia may be readable from the transparent substrate by altering the reflectivity of the transparent substrate in indicia portions that may be read by a scanner or reader (e.g., a barcode reader). The optically readable identification indicia may be provided on a common surface with a data zone in which data is encoded in the transparent substrate. Alternatively or additionally, the optically readable identification indicia may be provided on another, different surface than the surface on which the data is encoded in a data zone.

Abstract: A transparent substrate that encodes data therein having optically readable identification indicia corresponding to identifying information regarding the substrate. The optically readable identification indicia may be readable from the transparent substrate by altering the reflectivity of the transparent substrate in indicia portions that may be read by a scanner or reader (e.g., a barcode reader). The optically readable identification indicia may be provided on a common surface with a data zone in which data is encoded in the transparent substrate. Alternatively or additionally, the optically readable identification indicia may be provided on another, different surface than the surface on which the data is encoded in a data zone.

Abstract: Disclosed are methods related to identifying an essential gene which serves as an antibiotic target in a bacterium.

Abstract: Disclosed are methods related to identifying an essential gene which serves as an antibiotic target in a bacterium.

Abstract: Described is a method for screening an encoded chemical library, which library comprises a plurality of different chemical structures each releasably linked to an encoding tag, the method comprising the steps of: (a) providing said library of tagged chemical structures; (b) releasing each chemical structure from its tag to produce a plurality of free, tagless chemical structures (TCSs); (c) screening the TCSs by contacting them with a assay system under conditions whereby a spatial association between each TCS and its tag is maintained, to produce a plurality of different screened TCSs each spatially associated with its tag; and (d) identifying a screened TCS by decoding a tag that is spatially associated therewith.

Abstract: A server system comprising storage devices, processing devices and a storage fabric all operating according to a storage fabric protocol. The storage fabric comprises a plurality of individual switches having a modular design from which an overall switch is built, and the individual switches have individual respective configuration settings which determine which processing devices are allocated to use which of the storage devices. The system comprises an API enabling a software control function to configure the overall switch. The API is operable to receive from the control function an overall mapping of the storage devices to the processing devices instead of requiring the individual configuration settings of each of the individual switches to be specified by the control function, the API being configured to convert the overall mapping into the individual configuration settings of the individual switches to produce the overall mapping.

Abstract: Disclosed is an encoded chemical library microbead, which microbead has immobilized thereon and/or therein: (i) an encoding tag; and (ii) a target assay system reporter moiety, wherein the reporter moiety exists in a first state in the absence of activity against the target and in a second state in the presence of said activity, and wherein said microbead further comprises a clonal population of one or more chemical structure(s) releasably linked thereto and encoded by said tag.

Abstract: Methods and apparatus to align and couple aircraft are disclosed. An example apparatus for securing a first aircraft to a second aircraft includes a guide to direct movement of a first wing of the first aircraft relative to a second wing of the second aircraft to align the first wing with the second wing, and a lock configured to couple the first wing to the second wing after the guide aligns the first wing to the second wing.

Abstract: The present invention provides an apparatus for conducting an assay in a microfluidic system comprising magnetic beads, said apparatus comprising: a platform upon which a microfluidic system can be mounted, one or more actuators having a magnet, configured to directly influence movement of magnetic beads housed within a microfluidic system when a microfluidic system is mounted on said platform, and a control means configured to control relative movement of the one or more magnets, and a microfluidic system when mounted, to enable the magnet to trace a desired path across a mounted microfluidic system, said magnet being positionable at any x- and y-coordinates of a mounted microfluidic system, wherein said apparatus further comprises: a) at least one rotary actuator configured to enable magnet movement in an x-axis, and/or b) a means for moving a mounted microfluidic system in a stepwise fashion.

Abstract: A transparent substrate that encodes data therein having optically readable identification indicia corresponding to identifying information regarding the substrate. The optically readable identification indicia may be readable from the transparent substrate by altering the reflectivity of the transparent substrate in indicia portions that may be read by a scanner or reader (e.g., a barcode reader). The optically readable identification indicia may be provided on a common surface with a data zone in which data is encoded in the transparent substrate. Alternatively or additionally, the optically readable identification indicia may be provided on another, different surface than the surface on which the data is encoded in a data zone.

Abstract: A server system comprising storage devices, processing devices and a storage fabric all operating according to a storage fabric protocol. The storage fabric comprises a plurality of individual switches having a modular design from which an overall switch is built, and the individual switches have individual respective configuration settings which determine which processing devices are allocated to use which of the storage devices. The system comprises an API enabling a software control function to configure the overall switch. The API is operable to receive from the control function an overall mapping of the storage devices to the processing devices instead of requiring the individual configuration settings of each of the individual switches to be specified by the control function, the API being configured to convert the overall mapping into the individual configuration settings of the individual switches to produce the overall mapping.

Abstract: A system for conducting an assay comprises a power source (16), a controller (13) for controlling the assay and a plurality of assay units (14) operatively connected to one another such that the controller can communicate with the assay units and the system is capable of conducting the assay. An assay device comprises a substantially circular body (24) having a plurality of chambers in fluid connection such that fluid can pass between said chambers and a central hub (200) having a sample inlet (202) disposed therein for receiving a sample.

Abstract: A meter reading system comprises a sensor unit (2) containing a first camera (10) and at least a second camera (10?), the first camera focussed on a first area of a meter display (32) and the said second camera focussed on a second area of the meter display (32), the cameras arranged so that the area consisting of said first and second areas can be captured.

Abstract: A wavelength switchable laser is described which has a multi-wavelength laser source configured to generate signals at different wavelengths. The wavelength switchable laser has a wavelength selector with a plurality of electro-optical switches, each electro-optical switch being configurable to transmit or block output of one of the signals from the multi-wavelength source according to the wavelength of the signal.

Abstract: A server system comprising storage devices, processing devices and a storage fabric all operating according to a storage fabric protocol. The storage fabric comprises a plurality of individual switches having a modular design from which an overall switch is built, and the individual switches have individual respective configuration settings which determine which processing devices are allocated to use which of the storage devices. The system comprises an API enabling a software control function to configure the overall switch. The API is operable to receive from the control function an overall mapping of the storage devices to the processing devices instead of requiring the individual configuration settings of each of the individual switches to be specified by the control function, the API being configured to convert the overall mapping into the individual configuration settings of the individual switches to produce the overall mapping.

Abstract: A pannier mount assembly for attachment to a motorcycle frame comprises a first member attachable to the frame, the first member comprising a first pannier fixture point. The pannier mount assembly also comprises a second member comprising an elongate arm pivotably attached to the first member and comprising a second pannier fixture point. The second member has a free end. The second member is configured to pivot from a stored position where the free end is substantially adjacent to the first member to a deployed position where the free end is rotated away from the first member thereby increasing the separation between the first and second pannier fixture points.

Abstract: A modular system for building underwater robotic vehicles (URVs), including a pressure vessel system, modular chassis elements, a propulsion system and compatible buoyancy modules. The pressure vessel system uses standardized, interchangeable modules to allow for ease of modification of the URV and accommodation of different internal and external components such as sensors 4800 and computer systems. The system also includes standard, reconfigurable connections of the pressure vessel to the modular chassis system. A standardized, modular propulsion system includes a magnetic clutch, and a magnetic sleeve used to power the URV on or off.