Abstract: An apparatus for electrically contacting biological cells suspended in a liquid has a substrate having at least one opening and an electrode for electrically contacting a cell immobilized above the opening. A contact unit with a contact tip is arranged below said opening. A top end of the contact tip projects into the opening in such a way that it comes to bear against a cell membrane of the immobilized cell. The contact tip has a contact channel which ends at its top end. A hydrodynamic low pressure can be exerted upon the cell membrane via the contact channel, and the electrode is electrically connected to the contact channel. In a method for electrically contacting biological cells suspended in a liquid, a cell is immobilized above an opening provided in a substrate, and the immobilized cell is contacted via at least one electrode. For contacting the immobilized cell, a hydrodynamic low pressure is generated acting on a cell membrane through a contact tip projecting into the opening.

Abstract: An apparatus for electrically contacting biological cells suspended in a liquid has a substrate having at least one opening and an electrode for electrically contacting a cell immobilized above the opening. A contact unit with a contact tip is arranged below said opening. A top end of the contact tip projects into the opening in such a way that it comes to bear against a cell membrane of the immobilized cell. The contact tip has a contact channel which ends at its top end. A hydrodynamic low pressure can be exerted upon the cell membrane via the contact channel, and the electrode is electrically connected to the contact channel. In a method for electrically contacting biological cells suspended in a liquid, a cell is immobilized above an opening provided in a substrate, and the immobilized cell is contacted via at least one electrode. For contacting the immobilized cell, a hydrodynamic low pressure is generated acting on a cell membrane through a contact tip projecting into the opening.

Abstract: A retina implant including a chip adapted to be implanted into the interior of eye in subretinal contact with the retina. The chip has a plurality of pixel elements on a side thereof facing the lens for receiving an image projected into the retina and a plurality of electrodes for stimulating retina cells. The implants further includes a receiver coil for inductively coupling thereinto electromagnetic energy. The receiver coil coupled to a means for converting an alternating voltage induced into the receiver coil in a direct voltage suited for supplying the chip. The receiver coil is configured as a component separate from the chip, and for being positioned on the eye ball outside the sclera. The chip is connected to the receiver coil via a connecting lead which, in the implanted condition interconnects the interior and the exterior of the eye ball.

Abstract: A retina implant, comprises a surface and a plurality of pixel elements disposed on the surface for receiving and converting incoming light energy into electric energy. At least one amplifier is provided in the implant, and a plurality of stimulation electrodes supplied via the at least one amplifier as a function of signals received by the pixel elements. At least one light-sensitive reference element is coupled with the at least one amplifier for controlling amplification thereof as a function of light energy impinging on the at least one reference element.

Abstract: A support plate for carrying out functional tests on biological cells possesses raised sections which are spatially separated from each other and on which at least one measuring point, from an array of measuring points, is in each case arranged, with the cells being able to interact and bind at the measuring points. Trapping molecules, to which the cells are able to bind by means of their cell surface molecules, are immobilized at the measuring points, with the measuring points being separated from each other by regions of the support plate at which the cells cannot be immobilized (FIG. 4).

Abstract: An apparatus for electrically contacting biological cells suspended in a liquid has a substrate having at least one opening and an electrode for electrically contacting a cell immobilized above the opening. A contact unit with a contact tip is arranged below said opening. A top end of the contact tip projects into the opening in such a way that it comes to bear against a cell membrane of the immobilized cell. The contact tip has a contact channel which ends at its top end. A hydrodynamic low pressure can be exerted upon the cell membrane via the contact channel, and the electrode is electrically connected to the contact channel. In a method for electrically contacting biological cells suspended in a liquid, a cell is immobilized above an opening provided in a substrate, and the immobilized cell is contacted via at least one electrode. For contacting the immobilized cell, a hydrodynamic low pressure is generated acting on a cell membrane through a contact tip projecting into the opening.

Abstract: A device is disclosed for electrophysiological studies on biological material. The device comprises a support on which an array of measurement electrodes is arranged. A vessel is provided having a cavity for the biological material and an appropriate culture medium. The vessel is arranged on the support around the measurement electrodes in such a way that the latter are in electrical contact with the cavity. By means of a counter electrode, which is permanently arranged in the cavity, electrical signals can be measured between the measurement electrodes and the counter electrode.

Abstract: A retina implant to be implanted into an eye having an eye ball with an exterior and an interior, a sclera, a lens, and a retina is disclosed. The implant comprises a chip adapted to be implanted into the interior of the eye in contact with the retina. The chip, when in an implanted condition, has a plurality of pixel elements on a side thereof facing the lens for receiving an image projected onto the retina. The chip, further, comprises a plurality of electrodes for stimulating retina cells. The electrodes are located on the side of the chip having the pixel elements thereon, such that the chip is adapted to be implanted into a subretinal space of the eye. The implant, further, comprises a receiver coil for inductively coupling thereinto electromagnetic energy. The receiver coil is coupled to a means for converting an alternating voltage induced into the receiver coil in a direct voltage suited for supplying the chip.

Abstract: A retina implant, comprises a surface and a plurality of pixel elements disposed on the surface for receiving and converting incoming light energy into electric energy. At least one amplifier is provided in the implant, and a plurality of stimulation electrodes supplied via the at least one amplifier as a function of signals received by the pixel elements. At least one light-sensitive reference element is coupled with the at least one amplifier for controlling amplification thereof as a function of light energy impinging on the at least one reference element.