Patents by Inventor Hye-Jeong Shin

Hye-Jeong Shin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210078987
    Abstract: The present disclosure relates to a novel compound and a pharmaceutical composition comprising the same. The compound according to the present disclosure has effects for activating autophagy, and thus can be valuably used for preventing or treating diseases associated with autophagy regulation.
    Type: Application
    Filed: May 31, 2019
    Publication date: March 18, 2021
    Applicant: AUTOPHAGYSCIENCES INC.
    Inventors: Jung Ju KIM, Seong-Won SONG, Hye Jeong SHIN, Hyongwan CHOI
  • Publication number: 20190343718
    Abstract: The pillow of the present disclosure comprises: a first unit body and a second unit body which are arranged side by side in the left and right directions and are connected to each other with a variable gap therebetween; a third unit body which is coupled to the first unit body so as to move relative thereto in the forward and backward directions; a fourth unit body which is coupled to the second unit body so as to move relative thereto in the forward and backward directions, disposed in parallel to the third unit body in the left and right directions and coupled thereto with a variable gap therebetween; a first gap adjusting unit for allowing the third unit body and the fourth unit body to get further apart from or closer to each other in the forward and backward directions with respect to the first unit body and the second unit body; and a second gap adjusting unit for allowing the first unit body and the third unit body to get further apart from or closer to each other in the left and right directions with
    Type: Application
    Filed: January 4, 2018
    Publication date: November 14, 2019
    Inventors: Hye Jeong SHIN, Ji Woong PARK
  • Patent number: 8883134
    Abstract: The present disclosure provides a fusion protein comprising IL-1 receptor antagonist fused to a hybrid Fc. Particularly the present disclosure relates to a fusion protein comprising IL-1 receptor antagonist fused to a human immunoglobulin hybrid Fc fragment. In one embodiment, the hybrid Fc fragment comprises IgD and IgG4. Also provided is a pharmaceutical composition comprising the present fusion protein, which are useful for treating autoimmune disease including rheumatoid arthritis, inflammatory bowel disease (Crohn's disease, ulcerative colitis), psoriasis and diabetes and the like. The present fusion protein with excellent efficacy and reduced side effects is qualified for clinical development as therapeutic antibodies to treat autoimmune disease.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: November 11, 2014
    Assignees: Handok Pharmaceuticals, Inc., Genexine, Inc.
    Inventors: Young Gyu Cho, Hye Jeong Shin, Woon Young Lee, Woo Ick Jang
  • Publication number: 20130217864
    Abstract: The present disclosure provides a fusion protein comprising IL-1 receptor antagonist fused to a hybrid Fc. Particularly the present disclosure relates to a fusion protein comprising IL-1 receptor antagonist fused to a human immunoglobulin hybrid Fc fragment. In one embodiment, the hybrid Fc fragment comprises IgD and IgG4. Also provided is a pharmaceutical composition comprising the present fusion protein, which are useful for treating autoimmune disease including rheumatoid arthritis, inflammatory bowel disease (Crohn's disease, ulcerative colitis), psoriasis and diabetes and the like. The present fusion protein with excellent efficacy and reduced side effects is qualified for clinical development as therapeutic antibodies to treat autoimmune disease.
    Type: Application
    Filed: October 19, 2011
    Publication date: August 22, 2013
    Applicant: HANDOK PHARMACEUTICALS CO., LTD.
    Inventors: Young Gyu Cho, Hye Jeong Shin, Woon Young Lee, Woo Ick Jang
  • Publication number: 20120021044
    Abstract: The present invention provides a novel cationic lipid, a preparation method of the same and a delivery system comprising the same. The cationic lipid of the present invention is used for the preparation of delivery systems of nucleic acids or physiologically active anionic proteins. The cationic lipid of the present invention can be conveniently prepared and purified by a simple process and is therefore economically highly advantageous for industrial-scale production thereof. Further, a nucleic acid or protein delivery system comprising the cationic lipid of the present invention not only significantly improves the intracellular delivery efficiency of desired nucleic acid drugs (such as DNAs, RNAs, siRNAs, antisense oligonucleotides, and nucleic acid aptamers) or anionic proteins having physiological activity, but also is usefully used to augment therapeutic efficacy of nucleic acid or protein drugs due to attenuated cytotoxicity of the delivery system.
    Type: Application
    Filed: August 20, 2008
    Publication date: January 26, 2012
    Applicants: SNU R&DB FOUNDATION, KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Yu-Kyoung Oh, Min-Sung Suh, Hye-Jeong Shin, Ga Yong Shim
  • Publication number: 20100203112
    Abstract: The present invention provides a cationic phospholipid liposome composition comprising 1,2-dioleoyl-sn-glycero-S-ethylphosphocholine (EDOPC), 3?-[N—(N?,N?-dimethylaminoethane)-carbamoyl] cholesterol (DC-cholesterol) and 1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine (DPhPE), a liposome-nucleic acid complex which is capable of forming a complex therewith, and a pharmaceutical composition comprising the same. The cationic phospholipid liposome of the present invention is highly effective for intracellular delivery of nucleic acids and reduction of cytotoxicity, as compared to conventional liposome products. Therefore, the present invention can be useful for gene therapy via intracellular delivery of a desired material to target cells.
    Type: Application
    Filed: March 28, 2008
    Publication date: August 12, 2010
    Applicant: SNU R&DB FOUNDATION
    Inventors: Yu-Kyoung Oh, Hye-Jeong Shin, Min-Sung Suh, Ga Yong Shim