Patents by Inventor Hyoung-Joon Jin
Hyoung-Joon Jin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220054704Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.Type: ApplicationFiled: September 3, 2021Publication date: February 24, 2022Inventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
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Patent number: 11129921Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.Type: GrantFiled: May 8, 2019Date of Patent: September 28, 2021Assignee: Trustees of Tufts CollegeInventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
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Publication number: 20200282106Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.Type: ApplicationFiled: May 8, 2019Publication date: September 10, 2020Inventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
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Patent number: 10314938Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.Type: GrantFiled: February 16, 2017Date of Patent: June 11, 2019Assignee: TRUSTEES OF TUFTS COLLEGEInventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
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Publication number: 20170296696Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.Type: ApplicationFiled: February 16, 2017Publication date: October 19, 2017Inventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
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Patent number: 9623147Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.Type: GrantFiled: June 2, 2014Date of Patent: April 18, 2017Assignee: Trustees of Tufts CollegeInventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
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Patent number: 9370579Abstract: One aspect of the present invention relates to a method of preparing a fibrous protein smectic hydrogel by way of a solvent templating process, comprising the steps of pouring an aqueous fibrous protein solution into a container comprising a solvent that is not miscible with water; sealing the container and allowing it to age at about room temperature; and collecting the resulting fibrous protein smectic hydrogel and allowing it to dry.Type: GrantFiled: November 12, 2013Date of Patent: June 21, 2016Assignee: Trustees of Tufts CollegeInventors: Hyoung-Joon Jin, Jae-Hyung Park, Regina Valluzzi
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Patent number: 9084840Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.Type: GrantFiled: April 17, 2009Date of Patent: July 21, 2015Assignee: Trustees of Tufts CollegeInventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
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Publication number: 20150038043Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.Type: ApplicationFiled: June 2, 2014Publication date: February 5, 2015Applicant: TRUSTEES OF TUFTS COLLEGEInventors: David L. KAPLAN, Ung-Jin KIM, Jaehyung PARK, Hyoung-Joon JIN
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Publication number: 20140155496Abstract: One aspect of the present invention relates to a method of preparing a fibrous protein smectic hydrogel by way of a solvent templating process, comprising the steps of pouring an aqueous fibrous protein solution into a container comprising a solvent that is not miscible with water; sealing the container and allowing it to age at about room temperature; and collecting the resulting fibrous protein smectic hydrogel and allowing it to dry.Type: ApplicationFiled: November 12, 2013Publication date: June 5, 2014Applicant: Trustees of Tufts CollegeInventors: Hyoung-Joon Jin, Jae-Hyung Park, Regina Valluzzi
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Patent number: 8742069Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.Type: GrantFiled: March 14, 2013Date of Patent: June 3, 2014Assignee: Trustees of Tufts CollegeInventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
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Patent number: 8614293Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.Type: GrantFiled: November 3, 2009Date of Patent: December 24, 2013Assignee: Trustees of Tufts CollegeInventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
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Patent number: 8580924Abstract: One aspect of the present invention relates to a method of preparing a fibrous protein smectic hydrogel by way of a solvent templating process, comprising the steps of pouring an aqueous fibrous protein solution into a container comprising a solvent that is not miscible with water; sealing the container and allowing it to age at about room temperature; and collecting the resulting fibrous protein smectic hydrogel and allowing it to dry.Type: GrantFiled: August 6, 2009Date of Patent: November 12, 2013Assignee: Trustees of Tufts CollegeInventors: Hyoung-Joon Jin, Jae-Hyung Park, Regina Valluzzi
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Publication number: 20130165004Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.Type: ApplicationFiled: February 27, 2013Publication date: June 27, 2013Applicant: TRUSTEES OF TUFTS COLLEGEInventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
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Patent number: 8071722Abstract: The present invention provides an all-aqueous process and composition for production of silk biomaterials, e.g., fibers, films, foams and mats. In the process, at least one biocompatible polymer, such as poly(ethylene oxide) (PEO) (a well-documented biocompatible material), was blended with the silk protein prior to processing e.g., electrospinning. We discovered that this step avoids problems associated with conformational transitions of fibroin during solubilization and reprocessing from aqueous solution which lead to embrittled materials. Moreover, the process avoids the use of organic solvents that can pose problems when the processed biomaterials are exposed to cells in vitro or in vivo.Type: GrantFiled: January 15, 2010Date of Patent: December 6, 2011Assignees: Trustees of Tufts College, Massachusetts Institute of TechnologyInventors: David L. Kaplan, Hyoung-Joon Jin, Gregory Rutledge, Sergey Fridrikh
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Publication number: 20100294716Abstract: One aspect of the present invention relates to a method of preparing a fibrous protein smectic hydrogel by way of a solvent templating process, comprising the steps of pouring an aqueous fibrous protein solution into a container comprising a solvent that is not miscible with water; sealing the container and allowing it to age at about room temperature; and collecting the resulting fibrous protein smectic hydrogel and allowing it to dry.Type: ApplicationFiled: August 6, 2009Publication date: November 25, 2010Applicant: Trustees of Tufts CollegeInventors: Hyoung-Joon Jin, Jae-Hyung Park, Regina Valluzzi
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Publication number: 20100196447Abstract: The present invention provides an all-aqueous process and composition for production of silk biomaterials, e.g., fibers, films, foams and mats. In the process, at least one biocompatible polymer, such as poly(ethylene oxide) (PEO) (a well-documented biocompatible material), was blended with the silk protein prior to processing e.g., electrospinning. We discovered that this step avoids problems associated with conformational transitions of fibroin during solubilization and reprocessing from aqueous solution which lead to embrittled materials. Moreover, the process avoids the use of organic solvents that can pose problems when the processed biomaterials are exposed to cells in vitro or in vivo.Type: ApplicationFiled: January 15, 2010Publication date: August 5, 2010Applicants: TRUSTEES OF TUFTS COLLEGE, MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: David L. Kaplan, Hyoung-Joon Jin, Gregory Rutledge, Sergey Fridrikh
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Patent number: 7674882Abstract: The present invention provides an all-aqueous process and composition for production of silk biomaterials, e.g., fibers, films, foams and mats. In the process, at least one biocompatible polymer, such as poly(ethylene oxide) (PEO) (a well-documented biocompatible material), was blended with the silk protein prior to processing e.g., electrospinning. We discovered that this step avoids problems associated with conformational transitions of fibroin during solubilization and reprocessing from aqueous solution which lead to embrittled materials. Moreover, the process avoids the use of organic solvents that can pose problems when the processed biomaterials are exposed to cells in vitro or in vivo.Type: GrantFiled: December 23, 2004Date of Patent: March 9, 2010Assignees: Trustees of Tufts College, Massachusetts Institute of TechnologyInventors: David L. Kaplan, Hyoung-Joon Jin, Gregory Rutledge, Sergey Fridrikh
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Publication number: 20100055438Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.Type: ApplicationFiled: November 3, 2009Publication date: March 4, 2010Applicant: TRUSTEES OF TUFTS COLLEGEInventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
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Patent number: 7635755Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.Type: GrantFiled: October 11, 2005Date of Patent: December 22, 2009Assignee: Trustees of Tufts CollegeInventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin