Patents by Inventor Hyoung-Joon Jin

Hyoung-Joon Jin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170296696
    Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
    Type: Application
    Filed: February 16, 2017
    Publication date: October 19, 2017
    Inventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
  • Patent number: 9623147
    Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
    Type: Grant
    Filed: June 2, 2014
    Date of Patent: April 18, 2017
    Assignee: Trustees of Tufts College
    Inventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
  • Patent number: 9370579
    Abstract: One aspect of the present invention relates to a method of preparing a fibrous protein smectic hydrogel by way of a solvent templating process, comprising the steps of pouring an aqueous fibrous protein solution into a container comprising a solvent that is not miscible with water; sealing the container and allowing it to age at about room temperature; and collecting the resulting fibrous protein smectic hydrogel and allowing it to dry.
    Type: Grant
    Filed: November 12, 2013
    Date of Patent: June 21, 2016
    Assignee: Trustees of Tufts College
    Inventors: Hyoung-Joon Jin, Jae-Hyung Park, Regina Valluzzi
  • Patent number: 9084840
    Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
    Type: Grant
    Filed: April 17, 2009
    Date of Patent: July 21, 2015
    Assignee: Trustees of Tufts College
    Inventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
  • Publication number: 20150038043
    Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
    Type: Application
    Filed: June 2, 2014
    Publication date: February 5, 2015
    Applicant: TRUSTEES OF TUFTS COLLEGE
    Inventors: David L. KAPLAN, Ung-Jin KIM, Jaehyung PARK, Hyoung-Joon JIN
  • Publication number: 20140155496
    Abstract: One aspect of the present invention relates to a method of preparing a fibrous protein smectic hydrogel by way of a solvent templating process, comprising the steps of pouring an aqueous fibrous protein solution into a container comprising a solvent that is not miscible with water; sealing the container and allowing it to age at about room temperature; and collecting the resulting fibrous protein smectic hydrogel and allowing it to dry.
    Type: Application
    Filed: November 12, 2013
    Publication date: June 5, 2014
    Applicant: Trustees of Tufts College
    Inventors: Hyoung-Joon Jin, Jae-Hyung Park, Regina Valluzzi
  • Patent number: 8742069
    Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: June 3, 2014
    Assignee: Trustees of Tufts College
    Inventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
  • Patent number: 8614293
    Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
    Type: Grant
    Filed: November 3, 2009
    Date of Patent: December 24, 2013
    Assignee: Trustees of Tufts College
    Inventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
  • Patent number: 8580924
    Abstract: One aspect of the present invention relates to a method of preparing a fibrous protein smectic hydrogel by way of a solvent templating process, comprising the steps of pouring an aqueous fibrous protein solution into a container comprising a solvent that is not miscible with water; sealing the container and allowing it to age at about room temperature; and collecting the resulting fibrous protein smectic hydrogel and allowing it to dry.
    Type: Grant
    Filed: August 6, 2009
    Date of Patent: November 12, 2013
    Assignee: Trustees of Tufts College
    Inventors: Hyoung-Joon Jin, Jae-Hyung Park, Regina Valluzzi
  • Publication number: 20130165004
    Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
    Type: Application
    Filed: February 27, 2013
    Publication date: June 27, 2013
    Applicant: TRUSTEES OF TUFTS COLLEGE
    Inventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
  • Patent number: 8071722
    Abstract: The present invention provides an all-aqueous process and composition for production of silk biomaterials, e.g., fibers, films, foams and mats. In the process, at least one biocompatible polymer, such as poly(ethylene oxide) (PEO) (a well-documented biocompatible material), was blended with the silk protein prior to processing e.g., electrospinning. We discovered that this step avoids problems associated with conformational transitions of fibroin during solubilization and reprocessing from aqueous solution which lead to embrittled materials. Moreover, the process avoids the use of organic solvents that can pose problems when the processed biomaterials are exposed to cells in vitro or in vivo.
    Type: Grant
    Filed: January 15, 2010
    Date of Patent: December 6, 2011
    Assignees: Trustees of Tufts College, Massachusetts Institute of Technology
    Inventors: David L. Kaplan, Hyoung-Joon Jin, Gregory Rutledge, Sergey Fridrikh
  • Publication number: 20100294716
    Abstract: One aspect of the present invention relates to a method of preparing a fibrous protein smectic hydrogel by way of a solvent templating process, comprising the steps of pouring an aqueous fibrous protein solution into a container comprising a solvent that is not miscible with water; sealing the container and allowing it to age at about room temperature; and collecting the resulting fibrous protein smectic hydrogel and allowing it to dry.
    Type: Application
    Filed: August 6, 2009
    Publication date: November 25, 2010
    Applicant: Trustees of Tufts College
    Inventors: Hyoung-Joon Jin, Jae-Hyung Park, Regina Valluzzi
  • Publication number: 20100196447
    Abstract: The present invention provides an all-aqueous process and composition for production of silk biomaterials, e.g., fibers, films, foams and mats. In the process, at least one biocompatible polymer, such as poly(ethylene oxide) (PEO) (a well-documented biocompatible material), was blended with the silk protein prior to processing e.g., electrospinning. We discovered that this step avoids problems associated with conformational transitions of fibroin during solubilization and reprocessing from aqueous solution which lead to embrittled materials. Moreover, the process avoids the use of organic solvents that can pose problems when the processed biomaterials are exposed to cells in vitro or in vivo.
    Type: Application
    Filed: January 15, 2010
    Publication date: August 5, 2010
    Applicants: TRUSTEES OF TUFTS COLLEGE, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: David L. Kaplan, Hyoung-Joon Jin, Gregory Rutledge, Sergey Fridrikh
  • Patent number: 7674882
    Abstract: The present invention provides an all-aqueous process and composition for production of silk biomaterials, e.g., fibers, films, foams and mats. In the process, at least one biocompatible polymer, such as poly(ethylene oxide) (PEO) (a well-documented biocompatible material), was blended with the silk protein prior to processing e.g., electrospinning. We discovered that this step avoids problems associated with conformational transitions of fibroin during solubilization and reprocessing from aqueous solution which lead to embrittled materials. Moreover, the process avoids the use of organic solvents that can pose problems when the processed biomaterials are exposed to cells in vitro or in vivo.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: March 9, 2010
    Assignees: Trustees of Tufts College, Massachusetts Institute of Technology
    Inventors: David L. Kaplan, Hyoung-Joon Jin, Gregory Rutledge, Sergey Fridrikh
  • Publication number: 20100055438
    Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
    Type: Application
    Filed: November 3, 2009
    Publication date: March 4, 2010
    Applicant: TRUSTEES OF TUFTS COLLEGE
    Inventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
  • Patent number: 7635755
    Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
    Type: Grant
    Filed: October 11, 2005
    Date of Patent: December 22, 2009
    Assignee: Trustees of Tufts College
    Inventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
  • Publication number: 20090234026
    Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
    Type: Application
    Filed: April 17, 2009
    Publication date: September 17, 2009
    Applicant: TRUSTEES OF TUFTS COLLEGE
    Inventors: David L. Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
  • Patent number: 7572894
    Abstract: One aspect of the present invention relates to a method of preparing a fibrous protein smectic hydrogel by way of a solvent templating process, comprising the steps of pouring an aqueous fibrous protein solution into a container comprising a solvent that is not miscible with water; sealing the container and allowing it to age at about room temperature; and collecting the resulting fibrous protein smectic hydrogel and allowing it to dry.
    Type: Grant
    Filed: October 31, 2003
    Date of Patent: August 11, 2009
    Assignee: Trustees of Tufts College
    Inventors: Hyoung-Joon Jin, Jae-Hyung Park, Regina Valluzzi
  • Publication number: 20070187862
    Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
    Type: Application
    Filed: October 11, 2005
    Publication date: August 16, 2007
    Applicant: Trustees of Tufts College
    Inventors: David Kaplan, Ung-Jin Kim, Jaehyung Park, Hyoung-Joon Jin
  • Publication number: 20060205927
    Abstract: One aspect of the present invention relates to a method of preparing a fibrous protein smectic hydrogel by way of a solvent templating process, comprising the steps of pouring an aqueous fibrous protein solution into a container comprising a solvent that is not miscible with water; sealing the container and allowing it to age at about room temperature; and collecting the resulting fibrous protein smectic hydrogel and allowing it to dry.
    Type: Application
    Filed: October 31, 2003
    Publication date: September 14, 2006
    Applicant: Tufts University
    Inventors: Hyoung-Joon Jin, Jae-Hyung Park, Regina Valluzzi