Patents by Inventor Hyuk Soo EUN

Hyuk Soo EUN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PROVIDING THE INFORMATION FOR DIAGNOSING OF NONALCOHOLIC STEATOHEPATITIS
    Publication number: 20240341708
    Abstract: Provided is a method for providing the information for diagnosing nonalcoholic steatohepatitis.
    Type: Application
    Filed: March 25, 2024
    Publication date: October 17, 2024
    Applicant: CHUNGNAM NATIONAL UNIVERSITY HOSPITAL
    Inventors: Hyuk Soo EUN, Hong Jae JEON, Ha Neul KIM
  • METHOD FOR IMPROVEMENT OF DRUG METABOLISM OF HUMAN STEM CELL-DERIVED HEPATOCYTES
    Publication number: 20180163179
    Abstract: The present invention relates to a method for improving drug metabolism function of human stem cell-derived hepatocytes. More precisely, the human stem cell-derived hepatocytes are similar in cell morphology to human hepatocytes but display reduced expressions of drug or alcohol metabolism associated enzymes and antioxidant enzymes. So, the inventors co-cultured the hepatocytes differentiated from human stem cells with mouse hepatic stellate cells. As a result, it was confirmed that alcohol mediated toxicity was reduced so that liver cell damage or apoptosis level was reduced. In the meantime, the expressions of drug and alcohol metabolism associated enzymes and antioxidant enzymes were increased.
    Type: Application
    Filed: March 17, 2015
    Publication date: June 14, 2018
    Inventors: Won-il JEONG, Yong-Mahn HAN, Mi Young KIM, Hyuk Soo EUN, Mi-Jin JANG