Patents by Inventor Ian S. YOUNG

Ian S. YOUNG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11020490
    Abstract: In antibody-drug conjugates having tubulysin analog as the warhead, according to formula (III) the acetate group in the Tuv subunit (dotted box) demonstrates improved stability against hydrolytic cleavage.
    Type: Grant
    Filed: June 11, 2019
    Date of Patent: June 1, 2021
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ian S. Young, Sha Lou, Sanjeev Gangwar
  • Patent number: 10981914
    Abstract: Compounds having a structure according to formula (I), (II), or (III) where R1, R2, R3, R5 X1, X2, and X3 are as defined herein, are agonists for the Toll-like receptor 7 (TLR7) and can be used as adjuvants for stimulating the immune system. Some such compounds can be used in conjugates for targeted delivery to the organ or tissue of intended action.
    Type: Grant
    Filed: September 23, 2019
    Date of Patent: April 20, 2021
    Assignee: Bristol-Myers Squibb Companay
    Inventors: Ian S. Young, Sanjeev Gangwar, Shoshana L. Posy, Yam B. Poudel, Prasanna Sivaprakasam
  • Publication number: 20200017501
    Abstract: Compounds having a structure according to formula (I), (II), or (III) where R1, R2, R3, R5 X1, X2, and X3 are as defined herein, are agonists for the Toll-like receptor 7 (TLR7) and can be used as adjuvants for stimulating the immune system. Some such compounds can be used in conjugates for targeted delivery to the organ or tissue of intended action.
    Type: Application
    Filed: September 23, 2019
    Publication date: January 16, 2020
    Inventors: Ian S. YOUNG, Sanjeev Gangwar, Shoshana L. Posy, Yam B. Poudel, Prasanna Sivaprakasam
  • Publication number: 20190388553
    Abstract: In antibody-drug conjugates having tubulysin analog as the warhead, according to formula (III) the acetate group in the Tuv subunit (dotted box) demonstrates improved stability against hydrolytic cleavage.
    Type: Application
    Filed: June 11, 2019
    Publication date: December 26, 2019
    Inventors: Ian S. Young, Sha Lou, Sanjeev Gangwar
  • Patent number: 10457681
    Abstract: Compounds having a structure according to formula (I), (II), or (III) where R1, R2, R3, R5X1, X2, and X3 are as defined herein, are agonists for the Toll-like receptor 7 (TLR7) and can be used as adjuvants for stimulating the immune system. Some such compounds can be used in conjugates for targeted delivery to the organ or tissue of intended action.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: October 29, 2019
    Assignee: Bristol_Myers Squibb Company
    Inventors: Ian S. Young, Sanjeev Gangwar, Shoshana L. Posy, Yam B. Poudel, Prasanna Sivaprakasam
  • Publication number: 20190055244
    Abstract: Compounds having a structure according to formula (I), (II), or (III) where R1, R2, R3, R5X1, X2, and X3 are as defined herein, are agonists for the Toll-like receptor 7 (TLR7) and can be used as adjuvants for stimulating the immune system. Some such compounds can be used in conjugates for targeted delivery to the organ or tissue of intended action.
    Type: Application
    Filed: August 14, 2018
    Publication date: February 21, 2019
    Inventors: Ian S. YOUNG, Sanjeev GANGWAR, Shoshana L. POSY, Yam B. POUDEL, Prasanna SIVAPRAKASAM