Patents by Inventor Ibolya Horváth

Ibolya Horváth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190192336
    Abstract: The invention provides 1,4-dihydropyridine derivatives of formula (I) wherein R1 is optionally substituted C6-24aryl group or 5 to 6 membered heteroaryl group comprising 1 to 3 nitrogen atoms or other heteroatoms like oxygen and sulphur, and combinations thereof; R2 and R3 are independently hydrogen or C1-6alkyl group; R4 and R5 are independently hydrogen, C1-6alkyl group optionally substituted with amino, mono- or di(C1-6alkyl)amino, or with 5 to 24 membered optionally fused heterocyclic ring attached by nitrogen and optionally comprising additional 1 to 3 N, O, S heteroatoms and optionally substituted with C1-6alkyl group or C1-6 alkoxy group; R6 is C1-6alkyl, C3-7cycloalkyl, C3-7cycloalkylC1-6alkyl or arylC1-6alkyl group; and stereoisomers including enantiomers, diastereomers, racemic mixtures, mixture of enantiomers and combination thereof, as well as polymorphs, pharmaceutically acceptable salts, solvates, esters and prodrugs thereof for use in the therapeutic or prophylactic treatment of a disorder medi
    Type: Application
    Filed: February 28, 2019
    Publication date: June 27, 2019
    Inventors: Ferenc FÜLÖP, László VÍGH, Zsolt TÖRÖK, Botond PENKE, Ibolya HORVÁTH, Gábor BALOGH, Sándor BERNÁTH, Ákos HUNYA
  • Patent number: 10258498
    Abstract: The invention provides 1,4-dihydropyridine derivatives of formula (I) wherein R1 is optionally substituted C6-24aryl group or 5 to 6 membered heteroaryl group comprising 1 to 3 nitrogen atoms or other heteroatoms like oxygen and sulphur, and combinations thereof; R2 and R3 are independently hydrogen or C1-6alkyl group; R4 and R5 are independently hydrogen, C1-6alkyl group optionally substituted with amino, mono- or di(C1-6alkyl)amino, or with 5 to 24 membered optionally fused heterocyclic ring attached by nitrogen and optionally comprising additional 1 to 3 N, O, S heteroatoms and optionally substituted with C1-6alkyl group or C1-6 alkoxy group; R6 is C1-6alkyl, C3-7cycloalkyl, C3-7cycloalkylC1-6alkyl or arylC1-6alkyl group; and stereoisomers including enantiomers, diastereomers, racemic mixtures, mixture of enantiomers and combination thereof, as well as polymorphs, pharmaceutically acceptable salts, solvates, esters and prodrugs thereof for use in the therapeutic or prophylactic treatment of a disorder medi
    Type: Grant
    Filed: November 22, 2012
    Date of Patent: April 16, 2019
    Assignee: Richter Gedeon NYRT.
    Inventors: Ferenc Fülöp, László Vigh, Zsolt Török, Botond Penke, Ibolya Horváth, Gábor Balogh, Sándor Bernáth, Ákos Hunya
  • Patent number: 9475639
    Abstract: An inventory system can receive a receipt receptacle from a shipping vehicle. The receipt receptacle can be moved to a case shuttle without separating or sorting inventory items in the receipt receptacle. A mobile drive unit can move the case shuttle to a receiving station, where the receipt receptacle can be removed and where the inventory items can be stowed in a pickable inventory holder. A mobile drive unit can move the pickable inventory holder to an order-compiling station, where inventory items can be picked from the inventory holder into order receptacles. A mobile drive unit can move an order shuttle carrying order receptacles with completed orders to a shipping station, where the completed order receptacles can be transferred to a shipping vehicle.
    Type: Grant
    Filed: November 24, 2014
    Date of Patent: October 25, 2016
    Assignee: Amazon Technologies, Inc.
    Inventors: Michael Cordell Mountz, Jonathan Harris Schechter, John Joseph Enright, Joseph W. Durham, Ibolya Horvath, Eryk Brian Nice, Michael Harrison Decker, Peter R. Wurman, Robert Raymond Ambrogi, Timothy Aaron Bragg
  • Publication number: 20160145044
    Abstract: An inventory system can receive a receipt receptacle from a shipping vehicle. The receipt receptacle can be moved to a case shuttle without separating or sorting inventory items in the receipt receptacle. A mobile drive unit can move the case shuttle to a receiving station, where the receipt receptacle can be removed and where the inventory items can be stowed in a pickable inventory holder. A mobile drive unit can move the pickable inventory holder to an order-compiling station, where inventory items can be picked from the inventory holder into order receptacles. A mobile drive unit can move an order shuttle carrying order receptacles with completed orders to a shipping station, where the completed order receptacles can be transferred to a shipping vehicle.
    Type: Application
    Filed: November 24, 2014
    Publication date: May 26, 2016
    Inventors: Michael Cordell Mountz, Jonathan Harris Schechter, John Joseph Enright, Joseph W. Durham, Ibolya Horvath, Eryk Brian Nice, Michael Harrison Decker, Peter R. Wurman, Robert Raymond Ambrogi, Timothy Aaron Bragg
  • Publication number: 20140315893
    Abstract: The invention provides 1,4-dihydropyridine derivatives of formula (I) wherein R1 is optionally substituted C6-24aryl group or 5 to 6 membered heteroaryl group comprising 1 to 3 nitrogen atoms or other heteroatoms like oxygen and sulphur, and combinations thereof; R2 and R3 are independently hydrogen or C1-6alkyl group; R4 and R5 are independently hydrogen, C1-6alkyl group optionally substituted with amino, mono- or di(C1-6alkyl)amino, or with 5 to 24 membered optionally fused heterocyclic ring attached by nitrogen and optionally comprising additional 1 to 3 N, O, S heteroatoms and optionally substituted with C1-6alkyl group or C1-6 alkoxy group; R6 is C1-6alkyl, C3-7cycloalkyl, C3-7cycloalkylC1-6alkyl or arylC1-6alkyl group; and stereoisomers including enantiomers, diastereomers, racemic mixtures, mixture of enantiomers and combination thereof, as well as polymorphs, pharmaceutically acceptable salts, solvates, esters and prodrugs thereof for use in the therapeutic or prophylactic treatment of a disorder medi
    Type: Application
    Filed: November 22, 2012
    Publication date: October 23, 2014
    Inventors: Ferenc Fülöp, László Vígh, Zsolt Török, Botond Penke, Ibolya Horváth, Gábor Balogh, Sándor Bernáth, Ákos Hunya
  • Publication number: 20100267711
    Abstract: A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). The invention also provides novel hydroxylamine derivatives falling within the scope of the formulae (I) and (II) as well as pharmaceutical and/or cosmetical compositions comprising the said compounds.
    Type: Application
    Filed: June 25, 2010
    Publication date: October 21, 2010
    Applicant: CytRx Corporation
    Inventors: László Vígh, Péter Literáti Nagy, Jenó Szilbereky, László Ürögdi, Andrea Jednákovits, László Jaszlits, Katalin Bíró, Ede Màrvànyos, Mihály Barabás, Erzsébet Hegedüs, László Korányi, Mária Kürthy, Gábor Balogh, Ibolya Horváth, Zsolt Török, Éva Udvardy, György Dormán, Dénes Medzihradszky, Bea Mézes, Eszter Kovács, Ernó Duda, Beatrix Farkas, Attila Glatz
  • Patent number: 7745465
    Abstract: A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). The invention also provides novel hydroxylamine derivatives falling within the scope of the formulae (I) and (II) as well as pharmaceutical and/or cosmetical compositions comprising the said compounds.
    Type: Grant
    Filed: July 10, 2003
    Date of Patent: June 29, 2010
    Assignee: CytRx Corporation
    Inventors: László Vígh, Péter Literáti Nagy, Jenö Szilbereky, László Ürögdi, Andrea Jednákovits, László Jaszlits, Katalin Bíró, Ede Márványos, Mihály Barabás, Erzsébet Hegedüs, László Korányi, Mária Kürthy, Gábor Balogh, Ibolya Horváth, Zsolt Török, Éva Udvardy, György Dormán, Dénes Medzihradszky, Bea Mézes, Eszter Kovács, Ernö Duda, Beatrix Farkas, Attila Glatz
  • Patent number: 7148239
    Abstract: A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). The invention also provides novel hydroxylamine derivatives falling within the scope of the formulae (I) and (II) as well as pharmaceutical and/or cosmetical compositions comprising the said compounds.
    Type: Grant
    Filed: July 10, 2003
    Date of Patent: December 12, 2006
    Assignee: CytRx Corporation
    Inventors: László Vígh, Péter Literáti Nagy, Jenó Szilbereky, László Ürögdi, Andrea Jednákovits, László Jaszlits, Katalin Bíró, Ede Márványos, Mihály Barabás, Erzsébet Hegedüs, László Korányi, Mária Kürthy, Gábor Balogh, Ibolya Horváth, Zsolt Török, Éva Udvardy, György Dormán, Dénes Medzihradszky, Bea Mézes, Eszter Kovács, Ernó Duda, Beatrix Farkas, Attila Glatz
  • Publication number: 20040067940
    Abstract: A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). The invention also provides novel hydroxylamine derivatives falling within the scope of the formulae (I) and (II) as well as pharmaceutical and/or cosmetical compositions comprising the said compounds.
    Type: Application
    Filed: July 10, 2003
    Publication date: April 8, 2004
    Applicant: Biorex Research & Development Co.
    Inventors: Laszlo Vigh, Peter Literati Nagy, Jeno Szilbereky, Laszlo Urogdi, Andrea Jednakovits, Laszlo Jaszlits, Katalin Biro, Ede Marvanyos, Mihaly Barabas, Erzsebet Hegedus, Laszlo Koranyi, Maria Kurthy, Gabor Balogh, Ibolya Horvath, Zsolt Torok, Eva Udvardy, Gyorgy Dorman, Denes Medzihradszky, Bea Mezes, Eszter Kovacs, Erno Duda, Beatrix Farkas, Attila Glatz
  • Publication number: 20040019103
    Abstract: A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II).
    Type: Application
    Filed: July 10, 2003
    Publication date: January 29, 2004
    Applicant: Biorex Research & Development Co.
    Inventors: Laszlo Vigh, Peter Literati Nagy, Jeno Szilbereky, Laszlo Urogdi, Andrea Jednakovits, Laszlo Jaszlits, Katalin Biro, Ede Marvanyos, Mihaly Barabas, Erzsebet Hegedus, Laszlo Koranyi, Maria Kurthy, Gabor Balogh, Ibolya Horvath, Zsolt Torok, Eva Udvardy, Gyorgy Dorman, Denes Medzihradszky, Bea Mezes, Eszter Kovacs, Erno Duda, Beatrix Farkas, Attila Glatz
  • Patent number: 6653326
    Abstract: A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively; an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). The invention also provides novel hydroxyl amine derivatives falling within the scope of the formulae (I) and (II) as well as pharmaceutical and/or cosmetical compositions comprising the said compounds.
    Type: Grant
    Filed: December 7, 1999
    Date of Patent: November 25, 2003
    Assignee: Biorex Research & Development Co.
    Inventors: László Vígh, Péter Literáti Nagy, Jenó Szilbereky, László Ürögdi, Andrea Jednákovits, László Jaszlits, Katalin Bíró, Ede Màrvànyos, Mihály Barabás, Erzsébet Hegedüs, László Korányi, Mária Kürthy, Gábor Balogh, Ibolya Horváth, Zsolt Török, Éva Udvardy, György Dormán, Dénes Medzihradszky, Bea Mézes, Eszter Kovács, Ernö Duda, Beatrix Farkas, Attila Glatz
  • Patent number: 4554252
    Abstract: Disclosed is a process for improving the efficiency of in vitro propagation and tissue cultivating by tissue culture of cultivated of plants which comprises treating the plants during micropropagation and/or subsequent planting with an aqueous solution of one or a mixture of substituted amides or one or a mixture of substituted diamides.
    Type: Grant
    Filed: December 13, 1982
    Date of Patent: November 19, 1985
    Assignee: Eszakmagyarorszagi Vegyimuvek
    Inventors: Tibor Farkas, Laszlo Vigh, Ibolya Horvath, Aniko Nagy nee Vanicsek, Ferenc Foglein, Annamaria Meszaros, Istvan Toth
  • Patent number: 4493727
    Abstract: The invention relates to a plant growth regulating composition which contains as active agent a compound of general formula (I) ##STR1## wherein R.sub.1 and R.sub.2 can be identical or different and can stand for hydrogen, a C.sub.1-4 straight or branched alkyl group, cyclohexyl, phenyl, chlorophenyl, alkylphenyl, benzyl or alkylbenzyl group, or R.sub.1 and R.sub.2 can together with the N atoms form a heterocyclic ring.The growing of plants can be stimulated and the green weight can be increased to a significant degree by the treatment carried out with the composition of the invention.
    Type: Grant
    Filed: November 3, 1982
    Date of Patent: January 15, 1985
    Assignee: Eszakmagyarorszagi Vegyimuvek
    Inventors: Istvan Toth, Jozsef Nagy, Zsolt Dombay, Erzsebet Grega nee Toth, Ibolya Horvath, Laszlo Vigh, Tibor Farkas
  • Patent number: 4488901
    Abstract: The invention relates to new compositions for increasing the cold resistance of cultivated plants. These compositions contain as active ingredient at least one compound of the general formula (I), ##STR1## wherein n is an integer of 2 to 5 and R.sub.1, R.sub.2 and R.sub.3 each stand for hydrogen or C.sub.1-5 alkyl, or an acid addition salt thereof in an amount of 0.01 to 70% by weight, together with a conventional diluent and/or additive.The plants treated with the compositions according to the invention are more resistant to cold and frost.
    Type: Grant
    Filed: December 17, 1981
    Date of Patent: December 18, 1984
    Assignee: Eszakmagyarorszagi Vegyimuvek
    Inventors: Tibor Farkas, Ibolya Horvath, Laszlo I. Horvath, Laszlo Vigh, Zsolt Dombay, Jozsef Nagy, Emilia Nagy nee Gera, Csaba Pavliscsak, Gyula Tarpai