Patents by Inventor Igor V. Kutyavin

Igor V. Kutyavin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Covalently linked oligonucleotide minor grove binder conjugates
    Patent number: 5801155
    Abstract: Minor groove binding molecules are covalently bound to oligonucleotides which in their base sequence are complementary to a target sequence of single stranded or double stranded DNA, RNA or hybrids thereof. The covalently bound oligonucleotide minor groove binder conjugates strongly bind to the target sequence of the complementary strand.
    Type: Grant
    Filed: April 3, 1995
    Date of Patent: September 1, 1998
    Assignee: Epoch Pharmaceuticals, Inc.
    Inventors: Igor V. Kutyavin, Eugeny A. Lukhtanov, Howard B. Gamper, Rich B. Meyer, Jr.
  • Oligonucleotide-cyclopropapyrroloindole conjugates as sequence specific hybridization and crosslinking agents for nucleic acids
    Patent number: 5659022
    Abstract: Covalently linked conjugates of oligonucleotides (ODNs) with a cyclopropapyrroloindole moiety or an analog thereof, selectively and efficiently alkylate and crosslink with nucleic acid sequences that are complementary to the base sequence of the ODN.
    Type: Grant
    Filed: January 5, 1996
    Date of Patent: August 19, 1997
    Assignee: Epoch Pharmaceuticals, Inc.
    Inventors: Igor V. Kutyavin, Eugeny A. Lukhtanov, Howard B. Gamper, Rich B. Meyer, Jr., Alexander Gall