Patents by Inventor Ikunoshin Kato

Ikunoshin Kato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of Producing Extract Derived From Lyophyllum Ulmarium
    Publication number: 20100150955
    Abstract: A method of producing an extract derived from Lyophyllum ulmarium from fruiting body or mycelium of Lyophyllum ulmarium, wherein the method of producing an extract derived from Lyophyllum ulmarium uses an aqueous alkaline solvent as an extraction solvent; an extract derived from Lyophyllum ulmarium, obtainable by the method as defined above; and a food and a medicament each containing the extract.
    Type: Application
    Filed: August 2, 2006
    Publication date: June 17, 2010
    Inventors: Hiroshi Endo, Hitoshi Sakakibara, Yasushi Hattori, Kumi Sasaki, Ikunoshin Kato
  • Method of Producing Lymphocytes
    Publication number: 20100150886
    Abstract: A method for preparing lymphocytes characterized in that the method comprises the step of carrying out expansion in the presence of (a) fibronectin, a fragment thereof or a mixture thereof, (b) a CD3 ligand, and (c) a CD28 ligand.
    Type: Application
    Filed: August 10, 2006
    Publication date: June 17, 2010
    Applicant: TAKARA BIO INC.
    Inventors: Takahiro Marui, Kinuko Magamine, Nobuke Muraki, Akiko Kato, Tatsuji Enoki, Hiroaki Sagawa, Ikunoshin Kato
  • POLYPEPTIDES HAVING DNA POLYMERASE ACTIVITY
    Publication number: 20100143979
    Abstract: A polypeptide having a high fidelity DNA polymerase activity and thus being useful as a genetic engineering reagent; a gene encoding this polypeptide; a method of producing the polypeptide; and a method of amplifying a nucleic acid by using the polypeptide.
    Type: Application
    Filed: February 18, 2010
    Publication date: June 10, 2010
    Applicant: Takara Bio Inc.
    Inventors: Yoshimi SATO, Kazue Nishiwaki, Nana Shimada, Shigekazu Hokazono, Takashi Uemori, Hiroyuki Mukai, Ikunoshin Kato
  • FUNGAL BED CULTIVATION METHOD OF HON-SHIMEJI MUSHROOM
    Publication number: 20100139157
    Abstract: A fungal bed cultivation method of a hon-shimeji mushroom, in which the sprouting step and/or fruit body growing step is carried out under an environmental condition of high CO2 concentration, is provided. Examples of the environmental condition of high CO2 concentration include a CO2 concentration of 2,500 ppm or more in the sprouting step and a CO2 concentration of 5,000 ppm or more in the fruit body growing step. Since the formation ratio of a budlet in the fungal bed cultivation of a hon-shimeji mushroom is improved by embodiments of the present invention, stable production of a hon-shimeji mushroom by its large scale commercial cultivation becomes possible.
    Type: Application
    Filed: November 30, 2009
    Publication date: June 10, 2010
    Applicant: TAKARA BIO INC.
    Inventors: Takashi Kawai, Mayu Hashimoto, Takeshi Sugimori, Katsuhiko Kusakabe, Akihiko Kita, Ikunoshin Kato
  • DRUGS, FOODS OR DRINKS WITH THE USE OF ALGAE-DERIVED PHYSIOLOGICALLY ACTIVE SUBSTANCES
    Publication number: 20100137228
    Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.
    Type: Application
    Filed: August 11, 2008
    Publication date: June 3, 2010
    Applicant: TAKARA BIO INC.
    Inventors: Tatsuji ENOKI, Hiroaki SAGAWA, Takanari TOMINAGA, Eiji NISHIYAMA, Nobuto KOYAMA, Takeshi SAKAI, Fu-Gong YU, Katsushige IKAI, Ikunoshin KATO
  • VECTOR FOR GENE THERAPY
    Publication number: 20100137415
    Abstract: The present invention provides a retroviral vector containing a transcription unit comprising a transcription regulatory sequence and a gene encoding a polypeptide having single-stranded RNA-specific endoribonuclease activity which is placed so that its expression can be controlled by the regulatory sequence, wherein the unit is placed so that the direction of the transcription of mRNA from the unit is opposite to the direction of transcription of the RNA genome of the retroviral vector. By using the vector constructed as described above, viral supernatant showing high gene transfer efficiency can be prepared. The retroviral vector of the present invention is useful for the treatment and/or prevention of cancers and virus infections.
    Type: Application
    Filed: April 16, 2008
    Publication date: June 3, 2010
    Applicant: TAKARA BIO INC.
    Inventors: Hideto Chono, Kazuya Matsumoto, Hajima Matsumura, Junichi Mineno, Ikunoshin Kato
  • NUCLEIC ACID FOR TREATMENT OR PREVENTION OF IMMUNODEFICIENCY VIRUS INFECTION
    Publication number: 20100113566
    Abstract: A nucleic acid comprising a transcription regulation sequence whose transcription is induced by a trans-acting factor of a human immunodeficiency virus and a gene encoding a polypeptide having an endoribonuclease activity specific to single-stranded RNA, wherein the gene is located in such a position that the expression of the gene can be regulated by the transcription regulation sequence; a method for production of a cell showing an inhibited replication of a human immunodeficiency virus therein, the method comprising the step of introducing the nucleic acid into a cell; and a method for treatment or prevention of a human immunodeficiency virus infection.
    Type: Application
    Filed: August 10, 2006
    Publication date: May 6, 2010
    Inventors: Hideto Chono, Kazuya Matsumoto, Junichi Mineno, Ikunoshin Kato
  • PROCESS FOR PRODUCING OSTEOCALCIN-CONTAINING EXTRACT
    Publication number: 20100105867
    Abstract: A process for producing an extract containing activated osteocalcin; an extract which can be obtained by this production process; a food, a drink, a drug, an oral cavity-care composition and a feed containing this extract; and a growth enhancer containing osteocalcin originating in a bone.
    Type: Application
    Filed: March 5, 2008
    Publication date: April 29, 2010
    Applicant: TAKARA BIO INC.
    Inventors: Hiromu Ohnogi, Shinichi Adachi, Kazuo Nakagawa, Hiroki Iwamoto, Ikunoshin Kato
  • Polypeptides having DNA polymerase activity
    Patent number: 7704713
    Abstract: A polypeptide having a high fidelity DNA polymerase activity and thus being useful as a genetic engineering reagent; a gene encoding this polypeptide; a method of producing the polypeptide; and a method of amplifying a nucleic acid by using the polypeptide.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: April 27, 2010
    Assignee: Takara Bio Inc.
    Inventors: Yoshimi Sato, Kazue Nishiwaki, Nana Shimada, Shigekazu Hokazono, Takashi Uemori, Hiroyuki Mukai, Ikunoshin Kato
  • NOVEL ENDORIBONUCLEASE
    Publication number: 20100093026
    Abstract: A polypeptide having a novel endoribonuclease activity; a nucleic acid encoding the polypeptide; recombinant DNA having the nucleic acid therein; a transformant transformed with the recombinant DNA; a process for producing the polypeptide comprising the steps of cultivating the transformant and collecting the polypeptide from the culture; a process for producing a digest of single-stranded RNA comprising the step of reacting the polypeptide with the single-stranded RNA; and a method for the digestion of single-stranded RNA.
    Type: Application
    Filed: July 4, 2006
    Publication date: April 15, 2010
    Inventors: Masamitsu Shimada, Masanori Takayama, Kiyozo Asada, Ikunoshin Kato
  • Method for Production of T Cell Population
    Publication number: 20100068192
    Abstract: A method for preparing a T cell population, wherein the T cell population expresses CD45RA and expresses at least one selected from the group consisting of CD62L, CCR7, CD27, and CD28, characterized in that the method comprises the step of culturing a cell population comprising a T cell, in the presence of fibronectin, a fragment thereof or a mixture thereof.
    Type: Application
    Filed: September 27, 2006
    Publication date: March 18, 2010
    Applicant: TAKARA BIO INC.
    Inventors: Tatsuji Enoki, Akiko Kato, Mitsuko Ideno, Hiroaki Sagawa, Ikunoshin Kato
  • Fucoidan-containing cosmetics
    Patent number: 7678368
    Abstract: To find a substance which has a skin cosmeticizing effect such as prevention of skin aging, amelioriation of sensitive skin, or antipruritic action, and can serve as an effective ingredient for a hair-care product, thereby providing cosmetics comprising the effective ingredient. Concretely, there are provided cosmetics characterized in that the cosmetics comprise as an effective ingredient a compound selected from a fucoidan, a degradation product thereof, a sulfated monosaccharide or a salt thereof.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: March 16, 2010
    Assignee: Takara Bio Inc.
    Inventors: Shigetoshi Mizutani, Suzu Deguchi, Eiji Kobayashi, Eiji Nishiyama, Hiroaki Sagawa, Ikunoshin Kato
  • DRUGS, FOODS OR DRINKS WITH THE USE OF ALGAE-DERIVED PHYSIOLOGICALLY ACTIVE SUBSTANCES
    Publication number: 20100048491
    Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.
    Type: Application
    Filed: August 11, 2008
    Publication date: February 25, 2010
    Applicant: TAKARA BIO INC.
    Inventors: Tatsuji ENOKI, Hiroaki SAGAWA, Takanari TOMINAGA, Eiji NISHIYAMA, Nobuto KOYAMA, Takeshi SAKAI, Fu-Gong YU, Katsushige IKAI, Ikunoshin KATO
  • Therapeutic Agent
    Publication number: 20090292012
    Abstract: A therapeutic agent or prophylactic agent for a disease requiring an anti-foaming action for a cell and/or an inhibitory action for acyl-CoA cholesterol acyltransferase in treatment or prevention, characterized in that the therapeutic agent or prophylactic agent comprises as an effective ingredient a processed product derived from Peucedanum japonicum.
    Type: Application
    Filed: January 26, 2006
    Publication date: November 26, 2009
    Inventors: Tatsuji Enoki, Yoko Kudo, Katsumi Sugiyama, Hiromu Ohnogi, Hiroaki Sagawa, Ikunoshin Kato
  • Agarase and gene thereof
    Patent number: 7622291
    Abstract: Production of efficiently producing agaro-oligosaccharide; a polypeptide having an agarase activity which is usable in, for example, efficiently extracting a substance such as a nucleic acid from an agarose gel; the amino acid sequence of the polypeptide; a gene encoding the polypeptide; a process for producing the polypeptide; a process for producing agaro-oligosaccharide; and a process for extracting a substance such as a nucleic acid from an agarose gel.
    Type: Grant
    Filed: November 30, 2007
    Date of Patent: November 24, 2009
    Assignee: Takara Bio Inc.
    Inventors: Jun Tomono, Hiroaki Sagawa, Ikunoshin Kato
  • THERMOSTABLE RIBONUCLEASE H
    Publication number: 20090269809
    Abstract: A polypeptide having an RNaseH activity and being highly useful in gene engineering; a gene encoding this polypeptide; and a genetic engineering process for producing the polypeptide.
    Type: Application
    Filed: June 29, 2009
    Publication date: October 29, 2009
    Applicant: Takara Bio. Inc.
    Inventors: Shigekazu Hokazono, Takashi Uemori, Tetsuki Tanaka, Ikunoshin Kato
  • ?-agarase and process for producing the same
    Patent number: 7604962
    Abstract: A polypeptide having an ?-agarase activity, a gene encoding the polypeptide, a method for producing the polypeptide by genetic engineering and a method for producing an agarooligosaccharide using the polypeptide.
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: October 20, 2009
    Assignee: Takara Bio Inc.
    Inventors: Jun Tomono, Yoshiko Nomura, Hiroaki Sagawa, Takeshi Sakai, Ikunoshin Kato
  • Process for producing cytotoxic lymphocytes
    Publication number: 20090221077
    Abstract: The present invention provides a method for preparing a cytotoxic lymphocyte characterized in that the method comprises the step of carrying out at least one step selected from induction, maintenance and expansion of a cytotoxic lymphocyte using a medium containing serum and plasma at a total concentration of 0% by volume or more and less than 5% by volume, in the presence of fibronectin, a fragment thereof or a mixture thereof.
    Type: Application
    Filed: August 19, 2004
    Publication date: September 3, 2009
    Inventors: Mitsuko Ideno, Nobuko Muraki, Kinuko Ogawa, Masayuki Kishimoto, Tatsuji Enoki, Hiroaki Sagawa, Ikunoshin Kato
  • COMPOSITION FOR SUPPRESSING THE EXPRESSION OF FUCOSYLTRANSFERASE
    Publication number: 20090221065
    Abstract: Disclosed is a means for reducing the expression amount of a FUT8 gene, reducing the expression amount of a FUT8 protein, and/or reducing the expression amount of a product produced by the action of FUT8.
    Type: Application
    Filed: March 2, 2007
    Publication date: September 3, 2009
    Applicants: OSAKA UNIVERSITY, TAKARA BIO INC.
    Inventors: Akihiro Kondo, Wenzhe Li, Takatoshi Nakagawa, Nobuto Koyama, Naoyuki Taniguchi, Ikunoshin Kato
  • METHOD FOR GENE TRANSFER INTO TARGET CELLS WITH RETROVIRUS
    Publication number: 20090209730
    Abstract: A polypeptide represented by SEQ. ID No. 13 and a gene encoding the polypeptide. A gene is also represented by SEQ. ID No. 17, or a gene hybridizable thereto under stringent conditions and encoding a polypeptide which improves the efficiency of gene transfer into target cells with a retrovirus.
    Type: Application
    Filed: September 30, 2008
    Publication date: August 20, 2009
    Inventors: Kiyozo Asada, Takashi Uemori, Takashi Ueno, Nobuto Koyama, Kimikazu Hashino, Ikunoshin Kato