Abstract: The present application relates to an orally administered pharmaceutical composition or kit for eradicating Helicobacter pylori, including a complex of a non-absorbable antibiotic and a clay mineral. The pharmaceutical composition and kit of the present invention may further include a ?-lactam antibiotic and/or a gastric acid inhibitor.

Abstract: A pharmaceutical composition for treating Clostridioides difficile Infection (CDI), and a method for producing same. The pharmaceutical composition includes a complex of clay minerals, such as bentonite, and antibiotics, such as vancomycin. Accordingly, the pharmaceutical composition has an excellent treatment effect on CDI even with a significantly smaller amount of each of the existing antibiotics and clay minerals than the maximum recommended daily intake thereof, and has the effect of reducing side effects that can be caused by the massive intake of the antibiotics and clay minerals.

Abstract: According to one embodiment of the present invention, provided is a drug-clay mineral complex, in which the complex comprises a phospholipid, and the drug has an amine group.

Abstract: A drug and layered silicate composite is provided. The drug and layered silicate contains layered silicate powders and a drug compound bound to between layers of the silicate powders, wherein the drug compound is present in an amorphous state in the composite. Using such a composite may significantly improve absorption and bioavailability of a sorafenib compound.

Abstract: Disclosed are a controlled-release composition for oral administration comprising a complex of a hydrophilic alpha adrenergic blocker compound or its salt; and a clay mineral, and a method for preparing the same. The composition of the present disclosure has an in vivo release rate controlled further than that of conventional alpha adrenergic blocker compounds, thereby preventing side effects caused by a rapid increase in plasma drug concentration.

Abstract: Provided is a cosmetic composition comprising bentonite as an active ingredient. The cosmetic composition according to the present disclosure reduces the expression of inflammatory mechanism proteins and inflammatory mechanism genes in keratinocytes and hypodermal cells, exhibits an anti-inflammatory function, increases the moisture content of the skin, reduces redness in the skin, and increases the brightness of the skin, thereby being effective in skin whitening and skin moisturizing.

Abstract: Disclosed is an orally-administered pharmaceutical composition or kit for eradicating Helicobacter pylori comprising a complex of a non-absorbable antibiotic and a clay mineral. The pharmaceutical composition or kit of the present disclosure may further comprise a ?-lactam antibiotic and/or a gastric acid-suppressive agent.

Abstract: Provided is a pharmaceutical composition for preventing or treating metabolic bone diseases, containing bentonite as an active ingredient. The present disclosure relates to a composition for inhibiting bone resorption of osteoclasts and simultaneously, promoting bone formation of osteoblasts to be usable in the prevention or treatment of metabolic bone diseases such as osteoporosis, osteomalacia, osteopenia and bone atrophy.

Abstract: The present invention relates to a pharmaceutical composition for prevention, alleviation, and treatment of inflammatory bowel disease, the composition comprising a complex of a compound of Chemical Formula 1 or a pharmaceutically acceptable salt thereof and a clay mineral; a method for prevention, alleviation, and treatment of inflammatory bowel disease by using same; and a preparation method of the pharmaceutical composition.

Abstract: The present invention relates to a composition for oral administration with controlled release properties, comprising a complex of a compound of Chemical Formula 1 or a pharmaceutically acceptable salt thereof; and a clay mineral, and a method for preparing same.

Abstract: A composition for dyeing a bentonite, which includes a plant-derived polyphenol, and a method for dyeing a bentonite using the composition are provided. A composition for dyeing a bentonite, which includes a polyphenol such as lignin, pectin, tannin, and catechin, as a plant-derived material, and a method for dyeing a bentonite using the composition are provided.

Abstract: The present application relates to an orally administered pharmaceutical composition or kit for eradicating Helicobacter pylori, including a complex of a non-absorbable antibiotic and a clay mineral. The pharmaceutical composition and kit of the present invention may further include a ?-lactam antibiotic and/or a gastric acid inhibitor.

Abstract: A method for synthesizing high purity montmorillonite is disclosed. According to this synthesis method, bentonite is dissolved in aqua regia to produce a solution and then sodium hydroxide (NaOH) is added to the solution to produce a mixed solution. Then, the mixed solution is kept in a sealed state at a temperature of 90° C. inclusive to 100° C. exclusive to synthesize montmorillonite crystals.

Abstract: A drug and layered silicate composite is provided. The drug and layered silicate contains layered silicate powders; and a drug compound bound to between layers of the silicate powders, wherein the drug compound is present in an amorphous state in the composite. Using such a composite may significantly improve absorption and bioavailability of a sorafenib compound.

Abstract: A method of removing hydrous silica from bentonite includes irradiating an ultrasonic wave after preparing slurry by putting the bentonite and a sodium compound into distilled water or deionized water, adding the distilled water or the deionized water to the slurry, into which the ultrasonic wave is irradiated, to dilute and centrifugate the slurry, and drying a supernatant obtained through the centrifugation.

Abstract: A method of removing hydrous silica from bentonite includes irradiating an ultrasonic wave after preparing slurry by putting the bentonite and a sodium compound into distilled water or deionized water, adding the distilled water or the deionized water to the slurry, into which the ultrasonic wave is irradiated, to dilute and centrifugate the slurry, and drying a supernatant obtained through the centrifugation.

Abstract: An apparatus of producing a carbonate mineral includes a first reaction device including a fluid path along which an ion exchange solution moves; a cation exchange medium disposed in the fluid path, the cation exchange medium containing an alkaline earth metal; a second reaction device accommodating a sodium hydroxide aqueous solution and receiving the ion exchange solution containing an alkaline earth metal ion from the first reaction device; and a carbon dioxide supplying device supplying a carbon dioxide to the second aqueous solution.

Abstract: Provided is a portable ultraviolet device for exploring a mineral resource. The portable ultraviolet device for exploring the mineral resource may include a body, a visible component, an ultraviolet lamp assembly, and a darkroom component. The visible component is coupled to the body to pass through the body so that a mineral resource disposed at a lower portion of the body is observed from an upper side of the body. The ultraviolet lamp assembly part is coupled to the body to emit ultraviolet rays onto the mineral resource. The darkroom component is coupled to a bottom surface of the body to surround the visible component and the ultraviolet lamp assembly and defines an external light blocking space having an openable inlet in a lower portion of the body.

Abstract: Provided are embodiments of a section marking apparatus and method for dividing a geological survey site into one or more sections. In some embodiments, the section marking apparatus includes a case part, a fixing shaft part, a section marking part, and a driving pin part. The fixing shaft part is accommodated in the case part. The section marking part is coupled to the fixing shaft part, received in the case part, and has a marker string configured to be extracted to the outside of the case part. The driving pin part is coupled to the fixing shaft part and configured to be driven into a ground surface to secure the section marking apparatus to the ground surface. Accordingly, the section marking apparatus can be used to divide a site when the ground is flat or when the ground is uneven and/or has a slope.

Abstract: An apparatus of producing a carbonate mineral includes a first reaction device including a fluid path along which an ion exchange solution moves; a cation exchange medium disposed in the fluid path, the cation exchange medium containing an alkaline earth metal; a second reaction device accommodating a sodium hydroxide aqueous solution and receiving the ion exchange solution containing an alkaline earth metal ion from the first reaction device; and a carbon dioxide supplying device supplying a carbon dioxide to the second aqueous solution.