Patents by Inventor Ilya Chumakov

Ilya Chumakov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10874644
    Abstract: Compositions and methods for the treatment of Alzheimer's disease and related disorders. More particularly, disclosed are combined therapies that modulate synapse function for treating the disease.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: December 29, 2020
    Assignee: Pharnext
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Oxana Guerassimenko, Nathalie Cholet
  • Patent number: 10849851
    Abstract: The present invention relates to a homogeneous, stable, and palatable pharmaceutical solution comprising baclofen, sorbitol and naltrexone.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: December 1, 2020
    Assignee: Pharnext
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Viviane Bertrand
  • Publication number: 20200306211
    Abstract: The present invention relates to methods for improving dose finding process for combinations of several drugs and/or adapting the dosage of combinatorial treatment. More particularly the invention relates to methods for identifying more efficient dose of active pharmaceutical ingredients (APIs) within combination therapies. This invention also relates to methods for optimizing a therapeutic efficiency of combined therapies.
    Type: Application
    Filed: November 30, 2015
    Publication date: October 1, 2020
    Inventors: Daniel Cohen, Ilya Chumakov, Mickael Guedj, Rodolphe Hajj
  • Publication number: 20200237750
    Abstract: The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.
    Type: Application
    Filed: February 10, 2020
    Publication date: July 30, 2020
    Inventors: Daniel COHEN, Ilya CHUMAKOV, Serguei NABIROCHKIN
  • Publication number: 20200222409
    Abstract: The present invention relates to compositions and methods for controlling glycaemia in a mammalian in need thereof. The present invention relates to compositions and methods for the treatment of diabetes disease and related disorders. More specifically, the present invention relates to novel therapies or combinatorial therapies of diabetes and related disorders, based on compositions controlling the blood glucose level.
    Type: Application
    Filed: March 26, 2020
    Publication date: July 16, 2020
    Inventors: DANIEL COHEN, ILYA CHUMAKOV, SERGUEI NABIROCHKIN, RODOLPHE HAJJ
  • Patent number: 10682342
    Abstract: The present invention relates to compositions and methods for the treatment of amyotrophic lateral sclerosis. More specifically, the present invention relates to novel combinatorial therapies for treating amyotrophic lateral sclerosis or a related disorder.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: June 16, 2020
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Serguei Nabirochkin, Ilya Chumakov, Rodolphe Hajj
  • Publication number: 20200155491
    Abstract: Compositions and methods for the treatment of Charcot-Marie-Tooth disease and related disorders. Also provided are combination therapies for treating this disease by decreasing PMP22 expression in a subject.
    Type: Application
    Filed: September 27, 2019
    Publication date: May 21, 2020
    Inventors: Daniel COHEN, Ilya CHUMAKOV, Oxana GUERASSIMENKO, Serguei NABIROCHKIN
  • Patent number: 10617689
    Abstract: The present invention relates to compositions and methods for controlling glycaemia in a mammalian in need thereof. The present invention relates to compositions and methods for the treatment of diabetes disease and related disorders. More specifically, the present invention relates to novel therapies or combinatorial therapies of diabetes and related disorders, based on compositions controlling the blood glucose level.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: April 14, 2020
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Rodolphe Hajj
  • Patent number: 10596160
    Abstract: The present invention relates to compositions and methods for controlling glycemia in a mammalian in need thereof. The present invention relates to compositions and methods for the treatment of diabetes and related disorders. More specifically, the present invention relates to novel therapies or combinatorial therapies for diabetes and related disorders, based on compositions controlling the blood glucose level.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: March 24, 2020
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Rodolphe Hajj
  • Publication number: 20200085790
    Abstract: The present invention relates to combinations and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid ? toxicity. More specifically, the present invention relates to novel combinatorial therapies of Alzheimer's disease, Alzheimer's disease related disorders, amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury, based on baclofen and acamprosate combination.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 19, 2020
    Inventors: DANIEL COHEN, ILYA CHUMAKOV, SERGUEI NABIROCHKIN, EMMANUEL VIAL, MICKAEL GUEDJ
  • Patent number: 10583135
    Abstract: The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.
    Type: Grant
    Filed: December 27, 2016
    Date of Patent: March 10, 2020
    Assignee: Pharnext
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin
  • Publication number: 20200030314
    Abstract: The present invention provides methods for treating, preventing, or delaying the onset of Charcot-Marie-Tooth Disease type 1A (CMT1A), by administering to a subject in need thereof a combination comprising baclofen, sorbitol and naltrexone, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: July 8, 2019
    Publication date: January 30, 2020
    Inventors: Daniel Cohen, Ilya Chumakov, Rodolphe Hajj, Aude Milet, Serguei Nabirochkin, Klaus-Armin Nave, Thomas Prukop, Michael Sereda
  • Patent number: 10463640
    Abstract: Compositions and methods for the treatment of Charcot-Marie-Tooth disease and related disorders. Also provided are combination therapies for treating this disease by decreasing PMP22 expression in a subject.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: November 5, 2019
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Ilya Chumakov, Oxana Guerassimenko, Serguei Nabirochkin
  • Patent number: 10441558
    Abstract: Compositions and methods for the treatment of Charcot-Marie-Tooth disease and related disorders. Also provided are combination therapies for treating this disease by decreasing PMP22 expression in a subject.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: October 15, 2019
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Ilya Chumakov, Oxana Guerassimenko, Serguei Nabirochkin
  • Patent number: 10434109
    Abstract: The present invention relates to compositions and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid ? toxicity. More specifically, the present invention relates to novel combinatorial therapies of Multiple Sclerosis, Alzheimer's disease, Alzheimer's disease related disorders, Amyotrophic Lateral Sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: October 8, 2019
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Emmanuel Vial, Mickael Guedj
  • Publication number: 20190298698
    Abstract: Compositions and methods for the treatment of Alzheimer's disease and related disorders. More particularly, disclosed are combined therapies that modulate synapse function for treating the disease.
    Type: Application
    Filed: June 6, 2019
    Publication date: October 3, 2019
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Oxana Guerassimenko, Nathalie Cholet
  • Publication number: 20190290578
    Abstract: The present invention relates to a homogeneous, stable, and palatable pharmaceutical solution comprising baclofen, sorbitol and naltrexone.
    Type: Application
    Filed: April 3, 2019
    Publication date: September 26, 2019
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Viviane Bertrand
  • Patent number: 10383870
    Abstract: The present invention provides methods for treating, preventing, or delaying the onset of Charcot-Marie-Tooth Disease type 1A (CMT1A), by administering to a subject in need thereof a combination comprising baclofen, sorbitol and naltrexone, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: August 20, 2019
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Ilya Chumakov, Rodolphe Hajj, Aude Milet, Serguei Nabirochkin, Klaus-Armin Nave, Thomas Prukop, Michael Sereda
  • Patent number: 10350195
    Abstract: Compositions and methods for the treatment of Alzheimer's disease and related disorders. More particularly, disclosed are combined therapies that modulate synapse function for treating the disease.
    Type: Grant
    Filed: November 30, 2015
    Date of Patent: July 16, 2019
    Assignee: Pharnext
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Oxana Guerassimenko, Nathalie Cholet
  • Patent number: 10342768
    Abstract: The present invention relates to compositions and methods for the treatment of Parkinson's disease and related disorders. More specifically, the present invention relates to novel combinatorial therapies of Parkinson's disease and related disorders targeting the alpha-synuclein aggregation network. In particular, the invention relates to compounds which, alone or in combination(s), can effectively protect neuronal cells from alpha-synuclein aggregates. The invention also relates to methods of producing a drug or a drug combination for treating Parkinson's disease and to methods of treating Parkinson's disease or a related disorder.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: July 9, 2019
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Serguei Nabirochkin, Ilya Chumakov, Rodolphe Hajj