Patents by Inventor Isaac John Khan
Isaac John Khan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10945716Abstract: The present invention relates to devices for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart, and related methods of using such closure devices for closing the passageway. The method includes introducing a mechanical closure device into an atrium of the heart and transeptally deploying the closure device across the interatrial septum to provide proximation of the septum secundum and septum primum.Type: GrantFiled: December 18, 2017Date of Patent: March 16, 2021Assignee: CORDIS CORPORATIONInventors: Chao-Chin Chen, Randy David B Grishaber, Gene W Kammerer, Isaac John Khan, Jin Park
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Publication number: 20180125470Abstract: The present invention relates to devices for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart, and related methods of using such closure devices for closing the passageway. The method includes introducing a mechanical closure device into an atrium of the heart and transeptally deploying the closure device across the interatrial septum to provide proximation of the septum secundum and septum primum.Type: ApplicationFiled: December 18, 2017Publication date: May 10, 2018Applicant: CORDIS CORPORATIONInventors: CHAO-CHIN CHEN, RANDY DAVID B. GRISHABER, GENE W. KAMMERER, ISAAC JOHN KHAN, JIN PARK
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Patent number: 9861347Abstract: The present invention relates to devices for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart, and related methods of using such closure devices for closing the passageway. The method includes introducing a mechanical closure device into an atrium of the heart and transeptally deploying the closure device across the interatrial septum to provide proximation of the septum secundum and septum primum.Type: GrantFiled: March 29, 2012Date of Patent: January 9, 2018Assignee: CORDIS CORPORATIONInventors: Chao Chin-Chen, Randy David B. Grishaber, Gene W. Kammerer, Isaac John Khan, Jin Park
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Patent number: 8777984Abstract: A device and method for deploying a mechanical closure device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart. The deployment device has a first tubular structure having proximal and distal ends. A second tubular structure is substantially coaxial to and slideably engaged within the first tubular structure. The second tubular structure has a first substantially linear shape when constrained within the first tubular structure, and a second curvilinear shape when telescopically extended from the distal end of the first tubular structure. A third tubular structure is substantially coaxial to and slideably engaged within the second tubular structure. The third tubular structure is configured to provide sufficient rigidity to push the mechanical closure device from the distal end of the second tubular structure, and provide sufficient flexibility to assume a curvilinear shape when deflected by the second tubular structure.Type: GrantFiled: March 12, 2013Date of Patent: July 15, 2014Assignee: Cordis CorporationInventors: Chao-Chin Chen, Randy David B. Grishaber, Gene W. Kammerer, Isaac John Khan, Jin Park, Daniel Olsen
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Patent number: 8721707Abstract: An endoprosthetic device for treating abdominal aortic aneurysms using suprarenal fixation. A stent ring is anchored in an area above the renal arties using self-flaring barbs that project during the nitinol expansion process. Sutures extend from the stent ring to an area below the renal arties to a bifurcated trunk portion comprising a nitinol fabric on a non-kinking frame. The bifurcated trunk is sealed proximal the iliac arteries and includes iliac leg holders having self-flaring retention struts for non-traumatic holding of iliac leg prosthetics. Suprarenal fixation and collapsible cells having retention projections and barbs that only flare during the nitinol expansion process assist in lowering the devices profile and sheathability for percutaneous delivery and may provide for recapturing the anchored device.Type: GrantFiled: November 14, 2011Date of Patent: May 13, 2014Inventors: Donald D. Boucher, Michael Dugery, Kirk L. Johnson, Isaac John Khan, David C. Majercak, Scott Lyle Rush
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Patent number: 8702785Abstract: A prosthetic stent graft for the treatment of AAA includes a plurality of graft legs, each secured in a deployed position by a sealing gasket within a stent segment of the sealing gasket and to one side of a framing bracket. The framing bracket traverses the diameter of the stent segment and extends axially away, dividing the first stent segment into two portions, each portion for receiving a graft leg of the stent graft. The sealing gasket can include a stabilizer having a second generally cylindrical stent segment, and an extension bracket traversing the diameter of the second stent segment and extending away from the second stent segment. The extension bracket and the first bracket are connected with one another at a mutual generally central position.Type: GrantFiled: December 30, 2005Date of Patent: April 22, 2014Inventors: Isaac John Khan, David C. Majercak, Jin S. Park, Diana M. Sanchez
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Publication number: 20130296924Abstract: A device and method for deploying a mechanical closure device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart. The deployment device has a first tubular structure having proximal and distal ends. A second tubular structure is substantially coaxial to and slideably engaged within the first tubular structure. The second tubular structure has a first substantially linear shape when constrained within the first tubular structure, and a second curvilinear shape when telescopically extended from the distal end of the first tubular structure. A third tubular structure is substantially coaxial to and slideably engaged within the second tubular structure. The third tubular structure is configured to provide sufficient rigidity to push the mechanical closure device from the distal end of the second tubular structure, and provide sufficient flexibility to assume a curvilinear shape when deflected by the second tubular structure.Type: ApplicationFiled: March 12, 2013Publication date: November 7, 2013Inventors: Chao-Chin CHEN, Randy David B. Grishaber, Gene W. Kammerer, Isaac John Khan, Jin Park, Daniel Olsen
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Patent number: 8367110Abstract: Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with biocompatible diphenol compound monomer units with pendant carboxylic acid ester groups and poly(alkylene oxide) blocks, wherein the molar fraction in the copolymer of biocompatible diphenol compound monomer units with pendant carboxylic acid groups and poly(alkylene oxide) blocks relative to the weight percentage of the drug in the composition is effective to provide pseudo-zero order release of the drug from the composition during the sustained-release phase of drug delivery under physiological conditions. Ocular treatment methods and manufacturing methods are also disclosed.Type: GrantFiled: April 5, 2012Date of Patent: February 5, 2013Assignee: Rutgers, The State University of New JerseyInventors: Joachim B. Kohn, Isaac John Khan, Carmine P. Iovine
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Publication number: 20120207796Abstract: Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with biocompatible diphenol compound monomer units with pendant carboxylic acid ester groups and poly(alkylene oxide) blocks, wherein the molar fraction in the copolymer of biocompatible diphenol compound monomer units with pendant carboxylic acid groups and poly(alkylene oxide) blocks relative to the weight percentage of the drug in the composition is effective to provide pseudo-zero order release of the drug from the composition during the sustained-release phase of drug delivery under physiological conditions. Ocular treatment methods and manufacturing methods are also disclosed.Type: ApplicationFiled: April 5, 2012Publication date: August 16, 2012Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEYInventors: Joachim B. Kohn, Isaac John Khan, Carmine P. Iovine
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Publication number: 20120197292Abstract: The present invention relates to devices for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart, and related methods of using such closure devices for closing the passageway. The method includes introducing a mechanical closure device into an atrium of the heart and transeptally deploying the closure device across the interatrial septum to provide proximation of the septum secundum and septum primum.Type: ApplicationFiled: March 29, 2012Publication date: August 2, 2012Applicant: CORDIS CORPORATIONInventors: Chao Chin-Chen, Randy David B. Grishaber, Gene W. Kammerer, Isaac John Khan, Jin Park
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Patent number: 8173163Abstract: Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with biocompatible diphenol com-pound monomer units with pendant carboxylic acid ester groups and poly(alkylene oxide) blocks, wherein the molar fraction in the copolymer of biocompatible diphenol compound monomer units with pendant carboxylic acid groups and poly(alkylene oxide) blocks relative to the weight percentage of the drug in the composition is effective to provide pseudo-zero order release of the drug from the composition during the sustained-release phase of drug delivery under physiological conditions. Ocular treatment methods and manufacturing methods are also disclosed.Type: GrantFiled: February 20, 2009Date of Patent: May 8, 2012Assignee: Rutgers, The State University of New JerseyInventors: Joachim B. Kohn, Isaac John Khan, Carmine P. Lovine
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Patent number: 8083792Abstract: An endoprosthetic device for treating abdominal aortic aneurysms using suprarenal fixation. A stent ring is anchored in an area above the renal arteries using self-flaring barbs that project during the nitinol expansion process. Sutures extend from the stent ring to an area below the renal arteries to a bifurcated trunk portion comprising a nitinol fabric on a non-kinking frame. The bifurcated trunk is sealed proximal the iliac arteries and includes iliac leg holders having self-flaring retention struts for non-traumatic holding of iliac leg prosthetics. Suprarenal fixation and collapsible cells having retention projections and barbs that only flare during the nitinol expansion process assist in lowering the devices profile and sheathability for percutaneous delivery and may provide for recapturing the anchored device.Type: GrantFiled: January 24, 2006Date of Patent: December 27, 2011Assignee: Cordis CorporationInventors: Donald D. Boucher, Michael Dugery, Kirk L. Johnson, Isaac John Khan, David C. Majercak, Scott Lyle Rush
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Publication number: 20090238858Abstract: Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with biocompatible diphenol com-pound monomer units with pendant carboxylic acid ester groups and poly(alkylene oxide) blocks, wherein the molar fraction in the copolymer of biocompatible diphenol compound monomer units with pendant carboxylic acid groups and poly(alkylene oxide) blocks relative to the weight percentage of the drug in the composition is effective to provide pseudo-zero order release of the drug from the composition during the sustained-release phase of drug delivery under physiological conditions. Ocular treatment methods and manufacturing methods are also disclosed.Type: ApplicationFiled: February 20, 2009Publication date: September 24, 2009Applicant: Rutgers, The State University of New JerseyInventors: Joachim B. Kohn, Isaac John Khan, Carmine P. Iovine
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Publication number: 20070173929Abstract: An endoprosthetic device for treating abdominal aortic aneurysms using suprarenal fixation. A stent ring is anchored in an area above the renal arties using self-flaring barbs that project during the nitinol expansion process. Sutures extend from the stent ring to an area below the renal arties to a bifurcated trunk portion comprising a nitinol fabric on a non-kinking frame. The bifurcated trunk is sealed proximal the iliac arteries and includes iliac leg holders having self-flaring retention struts for non-traumatic holding of iliac leg prosthetics. Suprarenal fixation and collapsible cells having retention projections and barbs that only flare during the nitinol expansion process assist in lowering the devices profile and sheathability for percutaneous delivery and may provide for recapturing the anchored device.Type: ApplicationFiled: January 24, 2006Publication date: July 26, 2007Inventors: Donald D. Boucher, Michael Dugery, Kirk L. Johnson, Isaac John Khan, David C. Majercak, Scott Lyle Rush