Patents by Inventor Isaac John Khan

Isaac John Khan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180125470
    Abstract: The present invention relates to devices for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart, and related methods of using such closure devices for closing the passageway. The method includes introducing a mechanical closure device into an atrium of the heart and transeptally deploying the closure device across the interatrial septum to provide proximation of the septum secundum and septum primum.
    Type: Application
    Filed: December 18, 2017
    Publication date: May 10, 2018
    Applicant: CORDIS CORPORATION
    Inventors: CHAO-CHIN CHEN, RANDY DAVID B. GRISHABER, GENE W. KAMMERER, ISAAC JOHN KHAN, JIN PARK
  • Patent number: 9861347
    Abstract: The present invention relates to devices for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart, and related methods of using such closure devices for closing the passageway. The method includes introducing a mechanical closure device into an atrium of the heart and transeptally deploying the closure device across the interatrial septum to provide proximation of the septum secundum and septum primum.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: January 9, 2018
    Assignee: CORDIS CORPORATION
    Inventors: Chao Chin-Chen, Randy David B. Grishaber, Gene W. Kammerer, Isaac John Khan, Jin Park
  • Patent number: 8777984
    Abstract: A device and method for deploying a mechanical closure device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart. The deployment device has a first tubular structure having proximal and distal ends. A second tubular structure is substantially coaxial to and slideably engaged within the first tubular structure. The second tubular structure has a first substantially linear shape when constrained within the first tubular structure, and a second curvilinear shape when telescopically extended from the distal end of the first tubular structure. A third tubular structure is substantially coaxial to and slideably engaged within the second tubular structure. The third tubular structure is configured to provide sufficient rigidity to push the mechanical closure device from the distal end of the second tubular structure, and provide sufficient flexibility to assume a curvilinear shape when deflected by the second tubular structure.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: July 15, 2014
    Assignee: Cordis Corporation
    Inventors: Chao-Chin Chen, Randy David B. Grishaber, Gene W. Kammerer, Isaac John Khan, Jin Park, Daniel Olsen
  • Patent number: 8721707
    Abstract: An endoprosthetic device for treating abdominal aortic aneurysms using suprarenal fixation. A stent ring is anchored in an area above the renal arties using self-flaring barbs that project during the nitinol expansion process. Sutures extend from the stent ring to an area below the renal arties to a bifurcated trunk portion comprising a nitinol fabric on a non-kinking frame. The bifurcated trunk is sealed proximal the iliac arteries and includes iliac leg holders having self-flaring retention struts for non-traumatic holding of iliac leg prosthetics. Suprarenal fixation and collapsible cells having retention projections and barbs that only flare during the nitinol expansion process assist in lowering the devices profile and sheathability for percutaneous delivery and may provide for recapturing the anchored device.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: May 13, 2014
    Inventors: Donald D. Boucher, Michael Dugery, Kirk L. Johnson, Isaac John Khan, David C. Majercak, Scott Lyle Rush
  • Patent number: 8702785
    Abstract: A prosthetic stent graft for the treatment of AAA includes a plurality of graft legs, each secured in a deployed position by a sealing gasket within a stent segment of the sealing gasket and to one side of a framing bracket. The framing bracket traverses the diameter of the stent segment and extends axially away, dividing the first stent segment into two portions, each portion for receiving a graft leg of the stent graft. The sealing gasket can include a stabilizer having a second generally cylindrical stent segment, and an extension bracket traversing the diameter of the second stent segment and extending away from the second stent segment. The extension bracket and the first bracket are connected with one another at a mutual generally central position.
    Type: Grant
    Filed: December 30, 2005
    Date of Patent: April 22, 2014
    Inventors: Isaac John Khan, David C. Majercak, Jin S. Park, Diana M. Sanchez
  • Publication number: 20130296924
    Abstract: A device and method for deploying a mechanical closure device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart. The deployment device has a first tubular structure having proximal and distal ends. A second tubular structure is substantially coaxial to and slideably engaged within the first tubular structure. The second tubular structure has a first substantially linear shape when constrained within the first tubular structure, and a second curvilinear shape when telescopically extended from the distal end of the first tubular structure. A third tubular structure is substantially coaxial to and slideably engaged within the second tubular structure. The third tubular structure is configured to provide sufficient rigidity to push the mechanical closure device from the distal end of the second tubular structure, and provide sufficient flexibility to assume a curvilinear shape when deflected by the second tubular structure.
    Type: Application
    Filed: March 12, 2013
    Publication date: November 7, 2013
    Inventors: Chao-Chin CHEN, Randy David B. Grishaber, Gene W. Kammerer, Isaac John Khan, Jin Park, Daniel Olsen
  • Patent number: 8367110
    Abstract: Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with biocompatible diphenol compound monomer units with pendant carboxylic acid ester groups and poly(alkylene oxide) blocks, wherein the molar fraction in the copolymer of biocompatible diphenol compound monomer units with pendant carboxylic acid groups and poly(alkylene oxide) blocks relative to the weight percentage of the drug in the composition is effective to provide pseudo-zero order release of the drug from the composition during the sustained-release phase of drug delivery under physiological conditions. Ocular treatment methods and manufacturing methods are also disclosed.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: February 5, 2013
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Joachim B. Kohn, Isaac John Khan, Carmine P. Iovine
  • Publication number: 20120207796
    Abstract: Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with biocompatible diphenol compound monomer units with pendant carboxylic acid ester groups and poly(alkylene oxide) blocks, wherein the molar fraction in the copolymer of biocompatible diphenol compound monomer units with pendant carboxylic acid groups and poly(alkylene oxide) blocks relative to the weight percentage of the drug in the composition is effective to provide pseudo-zero order release of the drug from the composition during the sustained-release phase of drug delivery under physiological conditions. Ocular treatment methods and manufacturing methods are also disclosed.
    Type: Application
    Filed: April 5, 2012
    Publication date: August 16, 2012
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Joachim B. Kohn, Isaac John Khan, Carmine P. Iovine
  • Publication number: 20120197292
    Abstract: The present invention relates to devices for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart, and related methods of using such closure devices for closing the passageway. The method includes introducing a mechanical closure device into an atrium of the heart and transeptally deploying the closure device across the interatrial septum to provide proximation of the septum secundum and septum primum.
    Type: Application
    Filed: March 29, 2012
    Publication date: August 2, 2012
    Applicant: CORDIS CORPORATION
    Inventors: Chao Chin-Chen, Randy David B. Grishaber, Gene W. Kammerer, Isaac John Khan, Jin Park
  • Patent number: 8173163
    Abstract: Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with biocompatible diphenol com-pound monomer units with pendant carboxylic acid ester groups and poly(alkylene oxide) blocks, wherein the molar fraction in the copolymer of biocompatible diphenol compound monomer units with pendant carboxylic acid groups and poly(alkylene oxide) blocks relative to the weight percentage of the drug in the composition is effective to provide pseudo-zero order release of the drug from the composition during the sustained-release phase of drug delivery under physiological conditions. Ocular treatment methods and manufacturing methods are also disclosed.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: May 8, 2012
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Joachim B. Kohn, Isaac John Khan, Carmine P. Lovine
  • Patent number: 8083792
    Abstract: An endoprosthetic device for treating abdominal aortic aneurysms using suprarenal fixation. A stent ring is anchored in an area above the renal arteries using self-flaring barbs that project during the nitinol expansion process. Sutures extend from the stent ring to an area below the renal arteries to a bifurcated trunk portion comprising a nitinol fabric on a non-kinking frame. The bifurcated trunk is sealed proximal the iliac arteries and includes iliac leg holders having self-flaring retention struts for non-traumatic holding of iliac leg prosthetics. Suprarenal fixation and collapsible cells having retention projections and barbs that only flare during the nitinol expansion process assist in lowering the devices profile and sheathability for percutaneous delivery and may provide for recapturing the anchored device.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: December 27, 2011
    Assignee: Cordis Corporation
    Inventors: Donald D. Boucher, Michael Dugery, Kirk L. Johnson, Isaac John Khan, David C. Majercak, Scott Lyle Rush
  • Publication number: 20090238858
    Abstract: Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with biocompatible diphenol com-pound monomer units with pendant carboxylic acid ester groups and poly(alkylene oxide) blocks, wherein the molar fraction in the copolymer of biocompatible diphenol compound monomer units with pendant carboxylic acid groups and poly(alkylene oxide) blocks relative to the weight percentage of the drug in the composition is effective to provide pseudo-zero order release of the drug from the composition during the sustained-release phase of drug delivery under physiological conditions. Ocular treatment methods and manufacturing methods are also disclosed.
    Type: Application
    Filed: February 20, 2009
    Publication date: September 24, 2009
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Joachim B. Kohn, Isaac John Khan, Carmine P. Iovine
  • Publication number: 20070173929
    Abstract: An endoprosthetic device for treating abdominal aortic aneurysms using suprarenal fixation. A stent ring is anchored in an area above the renal arties using self-flaring barbs that project during the nitinol expansion process. Sutures extend from the stent ring to an area below the renal arties to a bifurcated trunk portion comprising a nitinol fabric on a non-kinking frame. The bifurcated trunk is sealed proximal the iliac arteries and includes iliac leg holders having self-flaring retention struts for non-traumatic holding of iliac leg prosthetics. Suprarenal fixation and collapsible cells having retention projections and barbs that only flare during the nitinol expansion process assist in lowering the devices profile and sheathability for percutaneous delivery and may provide for recapturing the anchored device.
    Type: Application
    Filed: January 24, 2006
    Publication date: July 26, 2007
    Inventors: Donald D. Boucher, Michael Dugery, Kirk L. Johnson, Isaac John Khan, David C. Majercak, Scott Lyle Rush