Abstract: The present disclosure relates to methods of inhibiting replication of a respiratory virus, and methods of treating or preventing a respiratory virus infection in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a N-glycosylation pathway inhibitor.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed for leak detection from a thief hatch. An example thief hatch includes a vent control stem coupled to first and second sealing plates, the first and second sealing plates to control fluid flow through the thief hatch based on translation of the vent control stem, and an indicator extending from the vent control stem to provide a visual indication of a condition of the fluid flow.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed for leak detection from a thief hatch. An example thief hatch includes a vent control stem coupled to first and second sealing plates, the first and second sealing plates to control fluid flow through the thief hatch based on translation of the vent control stem, and an indicator extending from the vent control stem to provide a visual indication of a condition of the fluid flow.

Abstract: Apparatus to protect sealing surfaces of thief hatches are disclosed. An example apparatus includes a first portion that is attachable to a tank, wherein the first portion includes a first opening, and a second portion that is pivotably coupled to the first portion. The example apparatus is structured to provide access to an aperture in the tank via the first opening when the second portion is in an open state and maintain a pressure of the tank within a specified range by selectively separating one or more seals from one or more corresponding sealing surfaces when the second portion is in a closed state, wherein the second portion includes the one or more seals and the one or more corresponding sealing surfaces.

Abstract: Disclosed herein are methods and systems for determining regions, domains, or amino acid residues of proteins that are intolerant to mutation. Also disclosed are applications for visualizing intolerant proteins regions, domains, and amino acid residues.

Abstract: Thief hatches with diaphragm assisted sealing are disclosed. An example apparatus includes a base attachable to a tank, and a cover attachable to the base via a hinge. The example apparatus further includes a vacuum seal assembly couplable to the cover, and a diaphragm coupled to a stem of the vacuum seal assembly. The diaphragm is moveable in response to a pressure differential between a first pressure within the tank and a second pressure exterior to the tank.

Abstract: Apparatus to protect sealing surfaces of thief hatches are disclosed. An example apparatus includes a first portion that is attachable to a tank, wherein the first portion includes a first opening, and a second portion that is pivotably coupled to the first portion. The example apparatus is structured to provide access to an aperture in the tank via the first opening when the second portion is in an open state and maintain a pressure of the tank within a specified range by selectively separating one or more seals from one or more corresponding sealing surfaces when the second portion is in a closed state, wherein the second portion includes the one or more seals and the one or more corresponding sealing surfaces.

Abstract: Apparatus to protect sealing surfaces of thief hatches are disclosed. An example apparatus includes a base attachable to a tank around an aperture in the tank. The example apparatus further includes a spacer supported by a support surface of the base. The example apparatus also includes a cover selectively moveable between a closed position covering the aperture and an open position providing access to the aperture, the spacer separating the cover from the base.

Abstract: Apparatus to protect sealing surfaces of thief hatches are disclosed. An example apparatus includes a base attachable to a tank around an aperture in the tank. The example apparatus further includes a spacer supported by a support surface of the base. The example apparatus also includes a cover selectively moveable between a closed position covering the aperture and an open position providing access to the aperture, the spacer separating the cover from the base.

Abstract: Thief hatches with diaphragm assisted sealing are disclosed. An example apparatus includes a base attachable to a tank, and a cover attachable to the base via a hinge. The example apparatus further includes a vacuum seal assembly couplable to the cover, and a diaphragm coupled to a stem of the vacuum seal assembly. The diaphragm is moveable in response to a pressure differential between a first pressure within the tank and a second pressure exterior to the tank.

Abstract: The present invention relates to a dual polarized dipole antenna (10) comprising a first dipole (21) and a second dipole (22); said first (21) and second (22) dipoles being substantially planar and being joined to each other to form a dual polarized dipole antenna (10); said dual polarized dipole antenna (10) including a separate parasitic cap element (50) attached to said first (21) and second (22) dipoles so as to secure said first (21) and second (22) dipoles to each other. The invention also includes an antenna system including a plurality of the dual polarized dipole antennas.

Abstract: A double port regulator assembly includes a first fluid port and a second fluid port. A fixed valve seat assembly is disposed proximate the first fluid port and a floating valve seat assembly is disposed proximate the second fluid port. A first valve plug cooperates with the fixed valve seat assembly to open and close the first fluid port and a second valve lug cooperates with the floating valve seat assembly to open and close the second fluid port. The floating valve seat assembly includes a floating valve seat that is movable with respect to the fixed valve seat.

Abstract: A double port regulator assembly includes a first fluid port and a second fluid port. A fixed valve seat assembly is disposed proximate the first fluid port and a floating valve seat assembly is disposed proximate the second fluid port. A first valve plug cooperates with the fixed valve seat assembly to open and close the first fluid port and a second valve lug cooperates with the floating valve seat assembly to open and close the second fluid port. The floating valve seat assembly includes a floating valve seat that is movable with respect to the fixed valve seat.

Abstract: A pressure control assembly is provided that is coupled to a fluid regulator having a regulator body, an actuator, and an exhaust vent. The actuator includes an actuator housing, a diaphragm disposed within the actuator housing, a first chamber defined adjacent a first side of the diaphragm, and second chamber defined adjacent a second side of the diaphragm. The exhaust vent is formed in the actuator housing to fluidly couple the first chamber to the atmosphere. The pressure control assembly includes a flexible element positioned within an orifice of the exhaust vent. The flexible element is movable within the orifice in response to changes in the pressure in the second chamber.

Abstract: A sliding gate regulator includes a valve body having a fluid inlet and a fluid outlet connected by a flow corridor. An opening is disposed in the valve body, the opening being oriented substantially perpendicularly to the flow corridor. A stationary plate and a slidable gate are disposed within the flow corridor, the slidable gate and the stationary plate cooperating to control fluid flow through the flow corridor. A removable plug is disposed within the opening in the valve body, the removable plug providing access to the stationary plate and to the slidable gate.

Abstract: A double port regulator assembly includes a first fluid port and a second fluid port. A fixed valve seat assembly is disposed proximate the first fluid port and a floating valve seat assembly is disposed proximate the second fluid port. A first valve plug cooperates with the fixed valve seat assembly to open and close the first fluid port and a second valve lug cooperates with the floating valve seat assembly to open and close the second fluid port. The floating valve seat assembly includes a floating valve seat that is movable with respect to the fixed valve seat.

Abstract: A sliding gate regulator includes a valve body having a fluid inlet and a fluid outlet connected by a flow corridor. An opening is disposed in the valve body, the opening being oriented substantially perpendicularly to the flow corridor. A stationary plate and a slidable gate are disposed within the flow corridor, the slidable gate and the stationary plate cooperating to control fluid flow through the flow corridor. A removable plug is disposed within the opening in the valve body, the removable plug providing access to the stationary plate and to the slidable gate.

Abstract: A double port regulator assembly includes a first fluid port and a second fluid port. A fixed valve seat assembly is disposed proximate the first fluid port and a floating valve seat assembly is disposed proximate the second fluid port. A first valve plug cooperates with the fixed valve seat assembly to open and close the first fluid port and a second valve lug cooperates with the floating valve seat assembly to open and close the second fluid port. The floating valve seat assembly includes a floating valve seat that is movable with respect to the fixed valve seat.

Abstract: The present invention relates to a dual polarized dipole antenna (10) comprising a first dipole (21) and a second dipole (22); said first (21) and second (22) dipoles being substantially planar and being joined to each other to form a dual polarized dipole antenna (10); said dual polarized dipole antenna (10) including a separate parasitic cap element (50) attached to said first (21) and second (22) dipoles so as to secure said first (21) and second (22) dipoles to each other. The invention also includes an antenna system including a plurality of the dual polarized dipole antennas.

Abstract: A pressure control assembly is provided that is coupled to a fluid regulator having a regulator body, an actuator, and an exhaust vent. The actuator includes an actuator housing, a diaphragm disposed within the actuator housing, a first chamber defined adjacent a first side of the diaphragm, and second chamber defined adjacent a second side of the diaphragm. The exhaust vent is formed in the actuator housing to fluidly couple the first chamber to the atmosphere. The pressure control assembly includes a flexible element positioned within an orifice of the exhaust vent. The flexible element is movable within the orifice in response to changes in the pressure in the second chamber.