Patents by Inventor Itai Adin

Itai Adin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10280173
    Abstract: Provided are ibrutinib polymorphs, e.g., crystalline ibrutinib Forms III, IV, V, VI, VII, VIII and Form IX and processes for producing these crystalline forms, stable amorphous ibrutinib and processes for preparing stable amorphous ibrutinib, pharmaceutical compositions comprising these forms and methods of using these crystalline and amorphous forms.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: May 7, 2019
    Assignee: WAVELENGTH ENTERPRISES LTD
    Inventors: Itai Adin, Sonia Krivonos, Yevgeny Rozenblat, Alex Weisman, Ana Fernandez Casares, Gloria Ten Figas, Revital Ben-Daniel
  • Publication number: 20180251463
    Abstract: Provided are ibrutinib polymorphs, e.g., crystalline ibrutinib Forms III, IV, V, VI, VII, VIII and Form IX and processes for producing these crystalline forms, stable amorphous ibrutinib and processes for preparing stable amorphous ibrutinib, pharmaceutical compositions comprising these forms and methods of using these crystalline and amorphous forms.
    Type: Application
    Filed: December 22, 2017
    Publication date: September 6, 2018
    Applicant: WAVELENGTH ENTERPRISES LTD.
    Inventors: Itai ADIN, Sonia KRIVONOS, Yevgeny ROZENBLAT, Alex WEISMAN, Ana FERNANDEZ CASARES, Gloria TEN FIGAS, Revital BEN-DANIEL
  • Patent number: 9884869
    Abstract: Provided are ibrutinib polymorphs, e.g., crystalline ibrutinib Forms III, IV, V, VI, VII, VIII and Form IX and processes for producing these crystalline forms, stable amorphous ibrutinib and processes for preparing stable amorphous ibrutinib, pharmaceutical compositions comprising these forms and methods of using these crystalline and amorphous forms.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: February 6, 2018
    Assignee: PERRIGO API LTD.
    Inventors: Itai Adin, Sonia Krivonos, Yevgeny Rozenblat, Alex Weisman, Ana Fernadez Casares, Gloria Ten Figas, Revital Ben-Daniel
  • Publication number: 20180002310
    Abstract: The present invention provides crystalline forms of efinaconazole, including crystalline efinaconazole forms designated herein as Form A, Form B and Form C, crystalline efinaconazole p-toluenesulfonate salt designated herein as Form I, and processes for their preparation.
    Type: Application
    Filed: December 2, 2015
    Publication date: January 4, 2018
    Applicant: Perrigo API Ltd.
    Inventors: Itai ADIN, Hila ELAZARI-SHALOM, Ori RORILK, Yana SERY
  • Publication number: 20170226108
    Abstract: Provided are ibrutinib polymorphs, e.g., crystalline ibrutinib Forms III, IV, V, VI, VII, VIII and Form IX and processes for producing these crystalline forms, stable amorphous ibrutinib and processes for preparing stable amorphous ibrutinib, pharmaceutical compositions comprising these forms and methods of using these crystalline and amorphous forms.
    Type: Application
    Filed: March 23, 2015
    Publication date: August 10, 2017
    Applicant: PERRIGO API LTD.
    Inventors: Itai ADIN, Sonia KERIVONOS, Yevgeny ROZENBLAT, Alex WEISMAN, Ana FERNADEZ CASARES, Gloria TEN FIGAS, Revital BEN-DANIEL
  • Publication number: 20100022609
    Abstract: Disclosed are novel crystalline forms of Temozolomide, methods of preparation thereof, medicaments including the novel crystalline forms of Temozolomide, and uses thereof in the treatment of medical conditions.
    Type: Application
    Filed: August 12, 2009
    Publication date: January 28, 2010
    Applicant: CHEMAGIS LTD.
    Inventors: Itai Adin, Carmen Iustain
  • Patent number: 7615632
    Abstract: Disclosed are novel crystalline forms of Temozolomide, methods of preparation thereof, medicaments including the novel crystalline forms of Temozolomide, and uses thereof in the treatment of medical conditions.
    Type: Grant
    Filed: December 30, 2004
    Date of Patent: November 10, 2009
    Assignee: Chemagis Ltd.
    Inventors: Itai Adin, Carmen Iustain
  • Patent number: 7544805
    Abstract: An amorphous form of montelukast sodium and a montelukast sodium lactose co-precipitate, processes for producing same, pharmaceutical compositions containing same and methods of treatment utilizing same are disclosed.
    Type: Grant
    Filed: February 3, 2005
    Date of Patent: June 9, 2009
    Assignee: Chemagis Ltd.
    Inventors: Mohammed Alnabari, Yana Sery, Itai Adin, Oded Arad, Joseph Kaspi
  • Publication number: 20080242696
    Abstract: Provided is crystalline granisetron base form I and processes for producing crystalline granisetron base form I, which is suitable for preparing, e.g., granisetron salts such as, e.g., the hydrochloride salt. Also provided is a process for producing a salt of granisetron from crystalline granisetron base form I.
    Type: Application
    Filed: March 27, 2007
    Publication date: October 2, 2008
    Applicant: CHEMAGIS LTD.
    Inventors: Yael Gafni, Alex Weisman, Itai Adin
  • Publication number: 20080234286
    Abstract: Provided herein is a spray dried stable amorphous imatinib mesylate as a free-flowing solid and process for producing the amorphous imatinib mesylate in highly pure form.
    Type: Application
    Filed: March 19, 2008
    Publication date: September 25, 2008
    Applicant: CHEMAGIS Ltd.
    Inventors: Alex Weisman, Sonia Krivonos, Edna Danon, Itai Adin, Carmen Iustain
  • Publication number: 20080194827
    Abstract: Novel crystalline forms of Donepezil base, processes for producing same, pharmaceutical compositions containing same and methods of treatment utilizing same are disclosed.
    Type: Application
    Filed: January 31, 2008
    Publication date: August 14, 2008
    Applicant: Chemagis Ltd.
    Inventors: Itai Adin, Carmen Iustain, Oded Arad, Joseph Kaspi
  • Publication number: 20070213365
    Abstract: Novel crystalline forms I, II, III, IV, V, VI, VII, VIII, IX, and X of montelukast ammonium salts are provided, and novel methods of making these forms are disclosed.
    Type: Application
    Filed: February 21, 2007
    Publication date: September 13, 2007
    Applicant: Chemagis Ltd.
    Inventors: Itai Adin, Zvicka Deutsch, Michael Brand, Moty Shookrun, Oded Arad, Joseph Kaspi
  • Publication number: 20070149782
    Abstract: The present invention relates to methods of preparing a highly pure crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone, which is a chemical intermediate useful in the preparation of Aripiprazole thereof in high quality and yield, and provides data that characterizes the crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-(1H)-quinolinone.
    Type: Application
    Filed: December 23, 2005
    Publication date: June 28, 2007
    Inventors: Michael Brand, Moty Shookrun, Irina Gribun, Itai Adin, Carmen Iustain, Oleg Braverman, Natalia Udis, Oded Arad, Joseph Kaspi
  • Patent number: 7208485
    Abstract: The present invention provides a crystalline halobetasol propionate selected from the group consisting of halobetasol propionate having crystalline Form I characterized by power X-ray diffraction peak positions and intensities as set forth in Table 1 herein, halobetasol propionate having crystalline Form II characterized by power X-ray diffraction peak positions and intensities as set forth in Table 2 herein, halobetasol propionate having crystalline Form III characterized by power X-ray diffraction peak positions and intensities as set forth in Table 3 herein, halobetasol propionate having crystalline Form IV characterized by power X-ray diffraction peak positions and intensities as set forth in Table 4 herein, halobetasol propionate having crystalline Form V characterized by power X-ray diffraction peak positions and intensities as set forth in Table 5 herein, and halobetasol propionate having crystalline Form VI characterized by power X-ray diffraction peak positions and intensities as set forth in Table 6
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: April 24, 2007
    Assignee: Chemagis Ltd.
    Inventors: Itai Adin, Yuri Futerman, Ori Lerman, Alexander Weisman, Chaim Ashkenazi, Joseph Kaspi
  • Publication number: 20060276525
    Abstract: Processes are disclosed for preparing Telmisartan form A, which is free-flowing and which does not contain electrostatic charge and is thus industrially process-able. The free-flowing Telmisartan form A is prepared by crystallization from a polar organic solvent e.g., DMSO, DMF, DMA, NMP, or water and is suitable for use in pharmaceutical compositions. A process is also disclosed for preparing highly-pure Telmisartan form A by precipitation from aqueous solutions.
    Type: Application
    Filed: May 17, 2006
    Publication date: December 7, 2006
    Inventors: Itai Adin, Carmen Iustain, Michael Brand, Ada Salman, Alexander Weisman
  • Publication number: 20060234996
    Abstract: A novel crystalline form of Ezetimibe and processes for the preparation thereof are disclosed.
    Type: Application
    Filed: April 13, 2006
    Publication date: October 19, 2006
    Inventors: Itai Adin, Carmen Iustain
  • Publication number: 20060223816
    Abstract: Provided is a process for preparing crystalline imatinib mesylate in substantially pure ?-form, which preferably includes crystallizing imatinib mesylate from an organic solvent containing imatinib and methanesulfonic acid, and seed crystals of imatinib mesylate ?-form, wherein the seed crystals are added before imatinib mesylate begins to precipitate from the mixture. Also provided are stable, free-flowing imatinib mesylate crystals in substantially pure ?-form, and a pharmaceutical composition containing the stable, free-flowing imatinib mesylate crystals.
    Type: Application
    Filed: May 8, 2006
    Publication date: October 5, 2006
    Applicant: CHEMAGIS LTD.
    Inventors: Itai Adin, Carmen Iustain, Guy Davidi, Alex Weisman, Moshe Bentolila, Elazar Meyer, Joseph Kaspi
  • Publication number: 20060223817
    Abstract: Provided is crystalline imatinib base form I and processes for producing crystalline imatinib base form I, which is suitable for preparing imatinib salts such as, e.g., the mesylate salt. Also provided is a process for producing a salt of imatinib from crystalline imatinib base form I.
    Type: Application
    Filed: May 15, 2006
    Publication date: October 5, 2006
    Applicant: CHEMAGIS LTD.
    Inventors: Itai Adin, Yuri Futerman, Carmen Iustain
  • Publication number: 20060223820
    Abstract: Provided are novel crystalline carboxylic acid salts of aripiprazole, methods of using such salts, and processes for producing such salts.
    Type: Application
    Filed: March 21, 2006
    Publication date: October 5, 2006
    Applicant: CHEMAGIS LTD.
    Inventors: Michael Brand, Moti Shookrun, Irina Gribun, Itai Adin, Carmen Iustain, Oded Arad, Joseph Kaspi
  • Publication number: 20060122226
    Abstract: Novel crystalline forms of Donepezil base, processes for producing same, pharmaceutical compositions containing same and methods of treatment utilizing same are disclosed.
    Type: Application
    Filed: December 8, 2004
    Publication date: June 8, 2006
    Inventors: Itai Adin, Carmen Iustain, Oded Arad, Joseph Kaspi