Abstract: Inactivated protein derivatives of the hIFN-? that preserve affinity to the hIFN-? receptor are useful in the treatment of autoimmune diseases, especially multiple sclerosis.

Abstract: A magnetic element and a method for making a magnetic element. The method includes patterning a first electrode material to form a first electrode on a substrate and depositing filler material on the substrate around the first electrode. The method further includes polishing to form a planar surface of filler and the first electrode. A magnetic cell is formed on the planar surface and a second electrode is formed on the magnetic cell. In some embodiments, the first electrode has an area that is at least 2:1 to the area of the magnetic cell.

Abstract: The invention relates to an inhibitor of endogenous human interferon-gamma (hIFN-ϝ) in autoimmune diseases, especially in multiple sclerosis. More precisely, the invention relates to inactivated protein derivatives of the hIFN-ϝ with preserved affinity to the hIFN-ϝ receptor. The derivatives represent genetically modified variants of hIFN-ϝ where the C-terminal part of the molecule is either deleted or replaced with a polypeptide sequence of another human protein and a recombinant hIFN-ϝ inactivated by physical or chemical methods.

Abstract: The invention relates to suppressor of the endogenous human interferon-gamma (hlFN-?) applicable in treatment of diseases associated with impaired activity of endogenous hlFN-?, especially autoimmune diseases and for prevention of graft arteriosclerosis and rejection of organs in allograft transplanted patients. It is based on inactive analogues of the hlFN-? with pre-served affinity to the hlFN-? receptor, genetically modified in the domain responsible for triggering the signal transduction pathway.

Abstract: Tracking system for flat mobile antenna, which includes: sensors for angular velocity (1), which sense the rotation of the antenna around their axes; sensors, sensing the orientation of the antenna according to vertical axis (2); control block (3), which calculates necessary corrections of the direction of antenna beam and which is connected to outputs of sensors (1, 2) and with inputs of driving block (4) and beam control block (5); at least one motor (7), which changes the orientation of the antenna and which is connected to the output of driving block (4) and which drives the antenna panel (8); block for electronic beam steering (5), which is connected to antenna panel (8); power supply block, which converts the voltage from the electrical network of the vehicle into suitable values for providing of power supply of all blocks of the system.

Abstract: The invention relates to an inhibitor of endogenous human interferon-gamma (hIFN-ϝ) in autoimmune diseases, especially in multiple sclerosis. More precisely, the invention relates to inactivated protein derivatives of the hIFN-ϝ with preserved affinity to the hIFN-ϝ receptor. The derivatives represent genetically modified variants of hIFN-ϝ, where the C-terminal part of the molecule is either deleted or replaced with a polypeptide sequence of another human protein and a recombinant hIFN-ϝ, inactivated by physical or chemical methods.

Abstract: A magnetic element and a method for making a magnetic element. The method includes patterning a first electrode material to form a first electrode on a substrate and depositing filler material on the substrate around the first electrode. The method further includes polishing to form a planar surface of filler and the first electrode. A magnetic cell is formed on the planar surface and a second electrode is formed on the magnetic cell. In some embodiments, the first electrode has an area that is at least 2:1 to the area of the magnetic cell.

Abstract: The invention relates to an inhibitor of endogenous human interferon-gamma (hIFN-ϝ) in autoimmune diseases, especially in multiple sclerosis. More precisely, the invention relates to inactivated protein derivatives of the hIFN-ϝ with preserved affinity to the hIFN-ϝ receptor. The derivatives represent genetically modified variants of hIFN-ϝ where the C-terminal part of the molecule is either deleted or replaced with a polypeptide sequence of another human protein and a recombinant hIFN-ϝ inactivated by physical or chemical methods.

Abstract: A method, system and article of manufacture for upgrade of a software module executed in a distributed software computer system using shadow installations of software modules for minimum downtime. A first software module is executed on a first host and a second software module is executed on a second host, the two software modules in communication with each other. Target release of the first software module and a local release of the second software module are installed and deployed on the first host during the execution of the first software module. The first software module is switched to the target release in communication with the local release of the second software module. The communication with the second software module is reestablished after the upgrade.

Abstract: A system and method are provided for an application server configuration tool. In an embodiment the configuration tool includes a data layer to store a configuration for an application server or a cluster of application servers. The data layer may include a database and a file system. The configuration tool may also include a logic layer having one or more logical tasks to implement the functions of the configuration tool. The configuration tool may also include a front-end layer which may have a graphical user interface; a markup language generator, and/or a console.

Abstract: A cable (1) comprises a conductor (3), an insulating layer (2) which forms a self-supporting ceramic layer when exposed to elevated temperatures experienced in a fire, and an additional heat transformable layer (4). The additional layer (4) can be another layer which forms a self-supporting ceramic layer when exposed to fire, or it can act as a sacrificial layer which decomposes at or below the temperature that the insulating layer forms a ceramic. The addition layer can enhance the strength of the layers before, during or after the fire, the structural integrity of the insulting layer (2) after the fire, the resistance of the layers to the ingress of water after the fire, or the electrical or thermal resistance of the layers during and after the fire.

Abstract: A cable (1) having a conductor (3), an insulating layer (2) which forms a self-supporting ceramic layer when exposed to elevated temperatures experienced in a fire, and an additional heat transformable layer (4). The additional layer (4) can be another layer which forms a self-supporting ceramic layer when exposed to fire, or it can act as a sacrificial layer which decomposes at or below the temperature that the insulating layer forms a ceramic. The addition layer can enhance the strength of the layers before, during or after the fire, the structural integrity of the insulating layer (2) after the fire, the resistance of the layers to the ingress of water after the fire, or the electrical or thermal resistance of the layers during and after the fire.

Abstract: Improved integrated circuits, memory devices, circuitry, and data methods are described that facilitate the adjustment and reconstruction of signal timing of devices by providing for an interface having inputs and/or outputs that are adjustably delayed. This allows embodiments of the present invention to sense the signal delay and utilize adjustable input or output delays to correct the signal timing relationships such that correctly timed communication signals are received by the internal circuitry of the device. In one embodiment of the present invention, a register is utilized to adjust the timing delay of individual input and/or output signals for the device. This increases the robustness of the device and its resistance to communication or data corruption, allowing larger ranges of environmental conditions and input capacitances of systems or communication busses to be tolerated.

Abstract: Improved integrated circuits, memory devices, circuitry, and data methods are described that facilitate the adjustment and reconstruction of signal timing of devices by providing for an interface having inputs and/or outputs that are adjustably delayed. This allows embodiments of the present invention to sense the signal delay and utilize adjustable input or output delays to correct the signal timing relationships such that correctly timed communication signals are received by the internal circuitry of the device. In one embodiment of the present invention, a register is utilized to adjust the timing delay of individual input and/or output signals for the device. This increases the robustness of the device and its resistance to communication or data corruption, allowing larger ranges of environmental conditions and input capacitances of systems or communication busses to be tolerated.

Abstract: Tracking system for flat mobile antenna, which includes: sensors for angular velocity (1), which sense the rotation of the antenna around their axes; sensors, sensing the orientation of the antenna according to vertical axis (2); control block (3), which calculates necessary corrections of the direction of antenna beam and which is connected to outputs of sensors (1, 2) and with inputs of driving block (4) and beam control block (5); at least one motor (7), which changes the orientation of the antenna and which is connected to the output of driving block (4) and which drives the antenna panel (8); block for electronic beam steering (5), which is connected to antenna panel (8); power supply block, which converts the voltage from the electrical network of the vehicle into suitable values for providing of power supply of all blocks of the system.

Abstract: A cable (1) comprises a conductor (3), an insulating layer (2) which forms a self-supporting ceramic layer when exposed to elevated temperatures experienced in a fire, and an additional heat transformable layer (4). The additional layer (4) can be another layer which forms a self-supporting ceramic layer when exposed to fire, or it can act as a sacrificial layer which decomposes at or below the temperature that the insulating layer forms a ceramic. The addition layer can enhance the strength of the layers before, during or after the fire, the structural integrity of the insulting layer (2) after the fire, the resistance of the layers to the ingress of water after the fire, or the electrical or thermal resistance of the layers during and after the fire.

Abstract: A fire resistant composition for forming a fire resistant ceramic at elevated temperatures, the composition comprising: at least 15% by weight based on the total weight of the composition of a polymer base composition comprising at least 50% by weight of an organic polymer; and at least 20% by weight based on the total weight of the composition of a silicate mineral filler; wherein upon exposure to an elevated temperature (experienced under fire conditions), the fire resistant composition is useful for passive fire protection applications, particularly cables, the fluxing oxide is present in an amount of from 1 to 15% by weight of the residue.

Abstract: A system and method are provided to configure a server node using a configuration tool. In an embodiment, a local node identifier is generated to identify a server node. One or more local properties of the server node may also be generated. In an embodiment, a cluster definition that is persistently stored on a database is updated with the one or more local properties.

Abstract: A system and method are provided for an application server configuration tool. In an embodiment the configuration tool includes a data layer to store a configuration for an application server or a cluster of application servers. The data layer may include a database and a file system. The configuration tool may also include a logic layer having one or more logical tasks to implement the functions of the configuration tool. The configuration tool may also include a front-end layer which may have a graphical user interface; a markup language generator, and/or a console.

Abstract: Improved integrated circuits, memory devices, circuitry, and data methods are described that facilitate the adjustment and reconstruction of signal timing of devices by providing for an interface having inputs and/or outputs that are adjustably delayed. This allows embodiments of the present invention to sense the signal delay and utilize adjustable input or output delays to correct the signal timing relationships such that correctly timed communication signals are received by the internal circuitry of the device. In one embodiment of the present invention, a register is utilized to adjust the timing delay of individual input and/or output signals for the device. This increases the robustness of the device and its resistance to communication or data corruption, allowing larger ranges of environmental conditions and input capacitances of systems or communication busses to be tolerated.