Abstract: A knife assembly for cutting a substrate during relative motion between the knife and the substrate, the assembly including a knife having a distal knife blade and a proximal knife shaft attached to a holder rotatable about a first axis perpendicular to the substrate to define a cut direction angle. The holder is also configured to rotate the knife blade about a second axis perpendicular to the first axis to form a notch angle relative to the first axis. The notch angle is preferably automatically infinitely adjustable within a range of angles. The holder may also, optionally, be configured to rotate the knife blade about a third axis perpendicular to a plane defined by the knife blade to adjust an angle of attack of the knife blade relative to the substrate.

Abstract: Systems and methods for processing a sheet having a printed underside. A gap between a feeder and a processing machine provides visibility to the printed underside, cameras capture images of the printed graphics through the gap, and a processor stitches the captured images together into a continuous image of the printed underside, including registration marks, corners or edges, and a sheet identifier. Processing instructions are retrieved from storage using the detected sheet identifier and are executed along processing paths calculated from detected information regarding locations of the registration marks and the corners or edges. A material guide positioned above the material path may be configured to constrain the sheet vertically as it passes over the gap and to reduce overhead light from interfering with the image capture.

Abstract: A cutting and stripping apparatus has a controller and causes a strip die to be prepared with cutouts according to a pre-determined pattern, e.g., on a cutting table and positioned on a stripping station that has a removal tool to remove waste material. After a sheet of material is cut on the same or another cutting table, the sheet is positioned in the stripping station over the female strip die. The removal tool moves to programmed positions in the stripping station and removes pieces of waste material. The final stripped cut sheet is the brought to the out-stack.

Abstract: A cutting and stripping apparatus has a controller and causes a strip die to be prepared with cutouts according to a pre-determined pattern, e.g., on a cutting table and positioned on a stripping station that has a removal tool to remove waste material. After a sheet of material is cut on the same or another cutting table, the sheet is positioned in the stripping station over the female strip die. The removal tool moves to programmed positions in the stripping station and removes pieces of waste material. The final stripped cut sheet is the brought to the out-stack.

Abstract: A strip die is prepared with cutouts according to a pre-determined pattern, e.g., on a cutting table and positioned on a stripping station that has a removal tool to remove waste material. After a sheet of material is cut on the same or another cutting table, the sheet is positioned in the stripping station over the female strip die. The removal tool moves to programmed positions in the stripping station and removes pieces of waste material. The final stripped cut sheet is the brought to the out-stack.

Abstract: A strip die is prepared with cutouts according to a pre-determined pattern, e.g., on a cutting table and positioned on a stripping station that has a removal tool to remove waste material. After a sheet of material is cut on the same or another cutting table, the sheet is positioned in the stripping station over the female strip die. The removal tool moves to programmed positions in the stripping station and removes pieces of waste material. The final stripped cut sheet is the brought to the out-stack.

Abstract: The present invention relates to association of one or more polymorphisms located in the human CEL gene to the occurrence of exocrine pancreatic dysfunction and a endocrine pancreatic dysfunction in the form of diabetes. The invention relates both to methods for diagnosing a predisposition to said diseases, classifying said diseases and to methods and compositions for treating subjects with said diseases. Furthermore the invention relates to screens for identifying compounds effective in treating said diseases. The invention describes specific single nucleotide polymorphisms the presence of which in the genome of an individual is strongly associated with the predisposition of said individual to exocrine pancreatic dysfunction and diabetes.