Patents by Inventor Ivo Fridolin

Ivo Fridolin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multiparametric Optical Method and Device for determining Uremic Solutes, including Uremix Toxins, in Biological Fluids
    Publication number: 20240102930
    Abstract: This invention relates to a novel method and a device for quantitative concentration measurements of protein bound and middle sized uremic toxins and advanced glycation end-products in the biological fluids, preferably in the spent dialysate. Invention combines unique spectral ranges of fluorescence and absorption to determine concentration of uremic toxins, such as indoxyl sulphate, beta-2-microglobulin and 4-pyridoxic acid in a way that provides significantly higher precision than previously known solutions.
    Type: Application
    Filed: March 31, 2022
    Publication date: March 28, 2024
    Applicant: TALLINN UNIVERSITY OF TECHNOLOGY
    Inventors: Jurgen ARUND, Risto TANNER, Ivo FRIDOLIN, Joosep PAATS
  • Method and device for determining content of the middle and protein bound uremic toxins in a biological fluid
    Patent number: 9103789
    Abstract: This invention relates to a novel method and a device for determining middle and protein bound uremic toxins in the biological fluids. More specifically, the present invention relates to an optical method utilizing fluorescence, preferable fluorescence of the spent dialysate, and a specific model, including a unique set of optical spectral components at certain wavelengths, to determine, preferable on-line, the concentration of the middle and protein bound uremic toxins such as beta2-microglobulin (B2M), and indoxyl sulfate (IS).
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: August 11, 2015
    Assignee: TALLINN UNIVERSITY OF TECHNOLOGY
    Inventors: Ivo Fridolin, Fredrik Uhlin, Jana Holmar, Risto Tanner, Jurgen Arund
  • METHOD AND DEVICE FOR DETERMINING CONTENT OF THE MIDDLE AND PROTEIN BOUND UREMIC TOXINS IN A BIOLOGICAL FLUID
    Publication number: 20130193347
    Abstract: This invention relates to a novel method and a device for determining middle and protein bound uremic toxins in the biological fluids. More specifically, the present invention relates to an optical method utilizing fluorescence, preferable fluorescence of the spent dialysate, and a specific model, including a unique set of optical spectral components at certain wavelengths, to determine, preferable on-line, the concentration of the middle and protein bound uremic toxins such as beta2-microglobulin (B2M), and indoxyl sulfate (IS).
    Type: Application
    Filed: June 28, 2011
    Publication date: August 1, 2013
    Applicant: Tallinn University of Technology
    Inventors: Ivo Fridolin, Fredrik Uhlin, Risto Tanner, Jurgen Arund
  • Method for determining waste products in the dialysis liquid in dialysis treatment
    Patent number: 6666840
    Abstract: Method and device for determining in dialysis treatment the content of waste products in the outgoing dialysis liquid from the dialyzer. Measurement of the concentration of a certain substance or a combination of substances included in the waste products is effected spectrophotometrically directly on the outgoing dialysis liquid from the dialyzer. For that purpose there is provided after the dialyzer in or after the dialysing machine a measuring cell for spectrophotometric measurement. The measurement value obtained is multiplied by the flow of dialysis liquid for determining the content of said substance or said combination of substances in the outgoing dialysis liquid from the dialyzer.
    Type: Grant
    Filed: April 30, 2001
    Date of Patent: December 23, 2003
    Assignee: Althin Medical AB
    Inventors: Thore Falkvall, Lars-Olof Sandberg, Ivo Fridolin, Lars-Goran Lindberg